Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(147 products)
- Cell wall(5 products)
- IL Receptor(113 products)
- IκB/IKK(61 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(445 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
Show 11 more subcategories
Found 3035 products of "Immunology and Inflammation"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Olendalizumab
CAS:<p>Olendalizumab (ALXN1007) is a humanized antibody targeting C5a for research on COVID-19-related inflammation.</p>Color and Shape:LiquidSuc-Tyr-Val-Ala-Asp-pNA
CAS:<p>Suc-YVAD-pNA, a chromogenic caspase-1 substrate.</p>Formula:C31H38N6O12Color and Shape:SolidMolecular weight:686.675M0324
<p>M0324 is a MUC-1 conditional CD40 agonist composed of an anti-MUC-1 IgG and two identical CD40-targeting camelid VHH domains, selectively activate immune cells.</p>Color and Shape:Odour LiquidDibenzothiophene
CAS:<p>Dibenzothiophene, a sulfur PAH in petroleum, has 3 rings and keratolytic properties.</p>Formula:C12H8SPurity:99.82%Color and Shape:Yellow To Green SolidMolecular weight:184.265(S),15(S)-DiHETE
CAS:<p>5(S),15(S)-DiHETE, made by 15-LO from 5(S)-HETE, boosts human PMNL degranulation via PAF, not fMLP/A23187/LTB4, and lures eosinophils at ED50 of 0.3μM.</p>Formula:C20H32O4Color and Shape:SolidMolecular weight:336.472Rabelomycin
CAS:<p>Rabelomycin is an angucycline group antibiotic.</p>Formula:C19H14O6Color and Shape:SolidMolecular weight:338.31BMP-4
CAS:<p>BMP-4, a heparin-binding peptide, exhibits anti-inflammatory and anti-chondrogenic properties. In murine chondrocytes and macrophages, it effectively mitigates inflammation and alleviates symptoms of various arthritides by dose-dependently suppressing the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6 through modulation of the iNOS-IFN-IL6 signaling pathway.</p>Formula:C52H93N25O13SColor and Shape:SolidMolecular weight:1308.52C6 L-threo Ceramide (d18:1/6:0)
CAS:<p>C6 L-threo Ceramide: bioactive sphingolipid, cytotoxic to U937 cells (IC50=18μM), non-metabolic, boosts IL-4 in T cells at 10μM.</p>Formula:C24H47NO3Color and Shape:SolidMolecular weight:397.63Anti-inflammatory agent 64
<p>Anti-inflammatory agent 64 (compound 4b) exhibits antioxidant and anti-inflammatory activities, effectively inhibiting the secretion of IL-6 and TNF-α while</p>Purity:98%Color and Shape:Odour SolidGinger extract
CAS:<p>Ginger extract demonstrates (exhibits) anti-cancer, anti-inflammatory, and chemotherapeutic properties in living organisms (in vivo).</p>Color and Shape:SolidNOX4-IN-1
<p>NOX4-IN-1 (Compound 14m) is an inhibitor of NADPH oxidase 4 (NOX4) that reduces the production of reactive oxygen species (ROS). It also inhibits the TGF-β1/Smad signaling pathway, leading to decreased expression of fibrosis-related proteins. Additionally, NOX4-IN-1 impedes the migration of NRK-49F cells.</p>Formula:C26H16ClN3O3Color and Shape:SolidMolecular weight:453.877DEPMPO-biotin
CAS:<p>DEPMPO is a stable nitrone for trapping O, N, S, C radicals, used in vivo/vitro with ESR. DEPMPO-biotin tags proteins' S-nitroso groups for analysis.</p>Formula:C24H42N5O8PSColor and Shape:SolidMolecular weight:591.66Croconazole
CAS:<p>Croconazole exhibited dose-dependent inhibitory activity on the 5-lipoxygenase (5-LOX) of neutrophils.</p>Formula:C18H15ClN2OPurity:99.71%Color and Shape:SolidMolecular weight:310.78Perfluorohexane
CAS:<p>Perfluorohexane (AF-0150) is a perfluorocarbon (PFC)-based microbubble formulation for ultrasound contrast and is developmentally toxic.</p>Formula:C6F14Purity:98%Color and Shape:Colourless LiquidMolecular weight:338.04Diplacol
CAS:<p>Diplacol, a geranylated flavanone isolated from Paulownia trees (Paulownia coreana UYEKI), exhibits anti-inflammatory properties by inhibiting NO production in LPS-stimulated Raw264.7 cells with an IC50 value of 4.53 μM [1].</p>Formula:C25H28O7Color and Shape:SolidMolecular weight:440.49Cartap hydrochloride
CAS:<p>Cartap hydrochloride is an insecticidal derivative. It is used to control chewing and sucking insects on many crops.</p>Formula:C18H33Cl2CuN3O3Color and Shape:Colorless Crystalline Slightly Hygroscopic Solid CoaMolecular weight:473.93CD19 CAR mRNA
<p>CD19 CAR mRNA expresses a protein for use in CAR-CD19 T cell therapy, targeting B cell antigen for cancer treatment.</p>Color and Shape:SolidCanakinumab
CAS:<p>Canakinumab: Human IL-1β antibody, anti-inflammatory, treats gout & coronary disease, IC50 of 43.6 pM (human), 40.8 pM (monkey).</p>Purity:98.8%Color and Shape:LiquidMolecular weight:145.18 kDaReltecimod TFA
<p>Reltecimod TFA (AB-103 TFA) is a CD28 antagonist and mimetic, inhibiting the stimulation of t-cells thereby attenuating acute inflammation NSTI.</p>Formula:C48H73F3N10O17SPurity:99.24% - 99.78%Color and Shape:SolidMolecular weight:1151.21CD19 CAR circRNA
<p>CD19 CAR circRNA expresses a CD19 car protein for CAR-T immunotherapy targeting B-cell antigens.</p>Color and Shape:SolidIM-250
CAS:<p>IM-250 possesses antiviral activity with IC values of 25 nM - 100 nM.</p>Formula:C20H19F2N3O2S2Purity:99.59%Color and Shape:SoildMolecular weight:435.51CD22 ligand-1
CAS:<p>CD22 ligand-1 is a potent, selective hCD22 binder (K D 0.335 µM) with potential for B-cell disease research.</p>Formula:C33H34N5NaO10Color and Shape:SolidMolecular weight:683.64Anti-inflammatory agent 58
<p>Anti-inflammatory agent 58 exhibits IL-1β inhibition with an IC50 value of 1.08 μM and suppresses pro-inflammatory gene expression, protein secretion, and NF-κB</p>Color and Shape:Odour SolidEblasakimab
CAS:<p>Eblasakimab (ASLAN004) is a humanized monoclonal antibody targeting IL-13α, which blocks IL-4 and IL-13 signaling through the type II receptor.</p>Purity:＞95%Color and Shape:LiquidPF-06342674
<p>PF-06342674 is a humanized monoclonal antibody targeting the IL-7 receptor-α, with immunoregulatory activity, used in Type 1 diabetes research.</p>Color and Shape:LiquidMolecular weight:145.5kDa3-(2-Hydroxyethyl) thio withaferin A
<p>3-(2-Hydroxyethyl) thio withaferin A, a steroidal lactone, blocks NF-kB, targets vimentin, and inhibits EPCR shedding.</p>Formula:C30H44O7SColor and Shape:SolidMolecular weight:548.73R1-ICR-5
CAS:<p>R1-ICR-5 is a selective PROTAC degrader targeting serine/threonine-protein kinase 1 (RIPK1). Mediated by VHL, R1-ICR-5 promotes the degradation of RIPK1, disrupting the TNFR1 and TLR3/4 signaling hubs, enhancing NF-κB, MAPK, and IFN signal output, and facilitating RIPK3 activation and necroptosis induction. R1-ICR-5 holds potential for research in cancer and inflammatory diseases.</p>Formula:C54H70N8O7S2Color and Shape:SolidMolecular weight:1007.314-Chlorochalcone
CAS:<p>4-Chlorochalcone is achalcone inhibit human MAO-B and ROS/RNS production and is able to inhibit the growth of CAL51 cells.</p>Formula:C15H11ClOPurity:98.08%Color and Shape:SolidMolecular weight:242.7Camstatin
CAS:<p>An analog of PEP-19 with enhanced binding to and antagonism of calmodulin.</p>Formula:C122H203N39O34Purity:98%Color and Shape:SolidMolecular weight:2760.19MUC1, mucin core
CAS:<p>MUC1: Type I transmembrane glycoprotein, overexpressed and abnormally glycosylated in cancer, binds ICAM-1 domain 1.</p>Formula:C61H101N19O24Color and Shape:SolidMolecular weight:1484.588Septeremophilane E
<p>Septeremophilane E, from Septoria rudbeckiae fungus, inhibits NO production.</p>Formula:C21H26O5Color and Shape:SolidMolecular weight:358.43Anticonvulsant agent 10
<p>Anticonvulsant agent 10 (Compound 6d) is an inhibitor targeting the Keap1-Nrf2 interaction, with a strong activity showing an ED50 of 0.04 mmol/kg. By inhibiting the Keap1-Nrf2 binding, it activates the Nrf2/ARE pathway, providing anticonvulsant and neuroprotective effects, making it useful for research in epilepsy and neuroprotection.</p>Color and Shape:Odour SolidCOX-2/15-LOX-IN-4
<p>COX-2/15-LOX-IN-4 (compound 5i) is a dual inhibitor with IC50 values of 0.075 μM for COX-2 and 1.97 μM for 15-LOX.</p>Formula:C23H20FN3OSPurity:98%Color and Shape:SolidMolecular weight:405.49NLRP3-IN-12
<p>NLRP3-IN-12 inhibits NLRP3 inflammasome, curbing IL-1β release with 0.45 μM IC50, for inflammatory bowel disease research.</p>Formula:C27H32ClNO7Color and Shape:SolidMolecular weight:518DC 07090
CAS:<p>DC 07090 is a human enterovirus 71 3C protease inhibitor with antiviral activity for the study of nucleic acid virus infections.</p>Formula:C18H14N4OPurity:97.34%Color and Shape:SolidMolecular weight:302.33CRX-526
CAS:<p>CRX-526, a TLR4 antagonist, protects against advanced diabetic nephropathy.</p>Formula:C69H127N2O19PPurity:98%Color and Shape:SolidMolecular weight:1319.72Amaroswerin
CAS:<p>Amaroswerin, a secoiridoid glucoside, has anti-inflammatory, antidiabetic, and other medicinal properties; it inhibits NO release at IC50 of 5.42 μg/mL.</p>Formula:C29H30O14Color and Shape:SolidMolecular weight:602.54AM-103 Free Acid
CAS:<p>AM-103 Free Acid is a bio-active chemical.</p>Formula:C36H39N3O4SColor and Shape:SolidMolecular weight:609.78NLRP3-IN-15
CAS:<p>NLRP3-IN-15: potent, selective NLRP3 inflammasome inhibitor; IC50 0.114 μM for IL-1β; for inflammation research.</p>Formula:C22H19NO4Color and Shape:SolidMolecular weight:361.39QX006N
<p>QX006N is a humanized monoclonal antibody inhibitor targeting the human interferon α/β receptor 1 (IFNAR1). It is promising for research in systemic lupus erythematosus (SLE) and other IFNAR1-related autoimmune diseases.</p>Color and Shape:Odour LiquidBCL6 PROTAC 1
CAS:<p>BCL6 PROTAC 1: Selective BCL6 degrader, IC50 8.8 µM, used in DLBCL research.</p>Formula:C45H52ClN9O12Color and Shape:SolidMolecular weight:946.41-Hydroxy-ibuprofen
CAS:<p>1-Hydroxy Ibuprofen, a metabolite in P. australis, targets COX-1/COX-2 with IC50s: 13 μM/370 μM.</p>Formula:C13H18O3Color and Shape:SolidMolecular weight:222.2802Crocin-4
CAS:<p>Crocin-4, a saffron carotenoid, is an antioxidant that inhibits Aβ deposits in the brain and may aid Alzheimer's research with anti-tumor effects.</p>Formula:C27H36O9Color and Shape:SolidMolecular weight:504.576KTX-612
CAS:<p>KTX-612 is a compound that serves as an orally active IRAK4 degrader, exhibiting a DC50 value of 7 nM. It is primarily utilized in oncology research [1].</p>Formula:C46H51F3N8O6Color and Shape:SolidMolecular weight:868.947-epi Maresin 1
CAS:<p>7-epi Maresin 1 is the inactive 7(S) epimer of Maresin 1 , which contains a 7(R) hydroxyl group. It can be used as an experimental negative control.</p>Formula:C22H32O4Color and Shape:SolidMolecular weight:360.494E7766 disodium
CAS:<p>E7766 disodium, a macrocycle-bridged STING agonist, exhibits a binding affinity (Kd) of 40 nM, demonstrating potent pan-genotypic and antitumor effects.</p>Formula:C24H26F2N10Na2O8P2S2Color and Shape:SolidMolecular weight:792.58Maritimetin
CAS:<p>Maritimein, an aurone from Coreopsis tinctoria, has potent antioxidant activity (IC50: 4.12 μM) and is used in cardiovascular research.</p>Formula:C15H10O6Color and Shape:SolidMolecular weight:286.24Dihydrorhodamine 6G
CAS:<p>DHR 6G, nonfluorescent reduced Rhodamine 6G, permeates cells, indicating ROS by oxidizing to fluorescent form in mitochondria.</p>Formula:C28H32N2O3Color and Shape:SolidMolecular weight:444.57UT-11
<p>UT-11: potent, brain-permeable mPGES-1 inhibitor. IC50: 0.10μM (human SK-N-AS), 2.00μM (murine BV2). Stops PGE2 production.</p>Formula:C17H19Cl2N3O2SColor and Shape:SolidMolecular weight:400.32EB-TCIP
<p>EB-TCIP (BAK-04-212) is a bivalent molecule composed of AP1867 and BI-3812. It facilitates the reversible formation of a ternary complex between FKBPF36V and BCL6BTB, thereby recruiting FKBP12F36V-tagged EWS/FLI1 to DNA sites bound by the transcriptional regulator BCL6, rapidly inducing expression of BCL6 target genes such as SOCS2 and CXCL11. EWS/FLI1 is a fusion transcription factor found in Ewing sarcoma. EB-TCIP is applicable for studying transcriptional dysregulation in cancer.</p>Color and Shape:Odour Solid
