Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(79 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
Show 11 more subcategories
Found 3045 products of "Immunology and Inflammation"
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Nepafenac-d5
CAS:<p>Nepafenac D5 is the deuterium labeled Nepafenac, which is a selective inhibitor of COX-2 .</p>Formula:C15H14N2O2Purity:98%Color and Shape:SolidMolecular weight:259.31Maresin 1
CAS:<p>Maresin 1 is biosynthesized by macrophages (MΦ) and possesses significant anti-inflammatory activity that attenuates LPS-induced lung injury in mice.</p>Formula:C22H32O4Color and Shape:SolidMolecular weight:360.49Etokimab
CAS:<p>Etokimab (ANB-020) is a humanised monoclonal antibody targeting IL-33, neutrophil migration, atopic dermatitis, asthma, and sinusitis.</p>Purity:95%Color and Shape:LiquidAHR-10037
CAS:<p>AHR-10037, a NSAID, offers pain relief, fever reduction, safety, and low stomach risk, acting as a prodrug for COX inhibitors.</p>Formula:C15H13ClN2O2Purity:98%Color and Shape:SolidMolecular weight:288.73(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one
CAS:(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one is a major mechanism of Sinomenine.Formula:C18H21NO4Purity:97.85%Color and Shape:SoildMolecular weight:315.36TMV-IN-9
CAS:<p>TMV-IN-9 (compound A6) is an antiviral agent that exhibits exceptional inactivation effects against Tobacco Mosaic Virus (TMV), with an EC50 of 62.8 μg/mL. It demonstrates strong binding capabilities to the TMV capsid protein, with a binding affinity of 1.862 μM. Moreover, TMV-IN-9 significantly disrupts the integrity of TMV particles, thereby preventing the virus from infecting the host.</p>Formula:C20H20O8Color and Shape:SolidMolecular weight:388.37D228
CAS:<p>D228 is an oral anti-inflammatory,inhibi B and T lymphocytes, down-regulation of MyD88/TRAF6/p38 and up-regulation of IL-10,inflammatory bowel disease (IBD).</p>Formula:C22H28O12Purity:99.91%Color and Shape:SolidMolecular weight:484.45FAPI-2
CAS:<p>FAPI-2 is a specific inhibitor of fibroblast-activated protein based on the radiotracer FAP labeling, and has anticancer activity.</p>Formula:C40H56N10O10Purity:98.76%Color and Shape:SolidMolecular weight:836.933,4-DAA
CAS:<p>3,4-DAA has anti-inflammatory activity and inhibits EOC20 cell-induced nitric oxide synthase (iNOS) induced by IFN-γ and lipopolysaccharide.</p>Formula:C18H17NO6Purity:98%Color and Shape:SolidMolecular weight:343.33Amfenac
CAS:<p>Amfenac promotes apoptosis in ARPE-19 cell culture.</p>Formula:C15H13NO3Color and Shape:SolidMolecular weight:255.27AZD4144
CAS:<p>AZD4144 is a potent and selective NLRP3 inhibitor (IC50 = 54 nM) that reducs IL-1β and IL-18 production for immune disorders.</p>Formula:C18H16F3N3O3Purity:99.02%Color and Shape:SoildMolecular weight:379.33Azacyclonol hydrochloride
CAS:<p>Azacyclonol hydrochloride can be used in the treatment of chronic schizophrenia.</p>Formula:C18H22ClNOColor and Shape:Off White Crystalline PowderMolecular weight:303.83Vopikitug
CAS:<p>Vopikitug is a humanized monoclonal antibody targeting IL-2RA with antitumor activity. It can be used to study cancer.</p>Purity:99.1% (SDS-PAGE); 96.5% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.5% (SEC-HPLC)Color and Shape:LiquidKamebakaurin
CAS:<p>Kamebakaurin combats liver toxicity, cancer, inflammation, and neuroinflammation by blocking NF-κB, HIF-1α, and key signaling pathways.</p>Formula:C20H30O5Purity:98.05%Color and Shape:SolidMolecular weight:350.45Avasopasem manganese
CAS:<p>Avasopasem manganese is a drug candidate of superoxide dismutase mimetic.</p>Formula:C21H35Cl2MnN5Purity:98%Color and Shape:SolidMolecular weight:483.38BMS-378806
CAS:BMS-378806 (BMS-806) selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.Formula:C22H22N4O4Purity:99.93%Color and Shape:SolidMolecular weight:406.43E3330
CAS:<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Formula:C21H30O6Purity:99.52%Color and Shape:SolidMolecular weight:378.46Pelubiprofen
CAS:<p>Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.</p>Formula:C16H18O3Purity:99.69%Color and Shape:SolidMolecular weight:258.31Catalase
CAS:<p>Catalase, an enzyme, metabolizes H2O2 and ROS; its expression and localization change significantly in tumors.</p>Purity:≥98%Color and Shape:Small Colorless Crystals Or Powder At Room Temperature Almost Odourless Small Colourless Crystals Or A White Crystalline PowderAllopurinol Sodium
CAS:<p>Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.</p>Formula:C5H4N4NaOPurity:99.93%Color and Shape:SolidMolecular weight:159.1TLR7 agonist 1
CAS:<p>TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).</p>Formula:C21H25N5OPurity:98%Color and Shape:SolidMolecular weight:363.46M62812 free base
CAS:<p>M62812 (free base), a Toll-like receptor 4 (TLR4) signal transduction inhibitor, suppresses activation of endothelial cells and leukocytes and prevents lethal</p>Formula:C13H11N3OSColor and Shape:SolidMolecular weight:257.31BAY32-5915
CAS:<p>BAY32-5915 is a selective inhibitor of IKKalpha.</p>Formula:C10H7NO3Purity:96.48% - 97%Color and Shape:Yellow Crystalline PowderMolecular weight:189.17OXSI-2
CAS:<p>OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.</p>Formula:C18H15N3O3SPurity:98%Color and Shape:Dark Orange SolidMolecular weight:353.39UC-781
CAS:<p>UC-781, a potent NNRTI, inhibits HIV-1 with a C50 of 5 nM and is stable across pH and temperatures.</p>Formula:C17H18ClNO2SPurity:92.17%Color and Shape:SolidMolecular weight:335.85MIF-IN-2
CAS:<p>MIF-IN-2 is a MIF inhibitor with anticancer activity for the study of cancer and autoimmune diseases.</p>Formula:C14H10ClN3O4Purity:98.55%Color and Shape:SolidMolecular weight:319.7TRAF-STOP inhibitor 6877002
CAS:<p>TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.</p>Formula:C17H17NOPurity:99.76%Color and Shape:SolidMolecular weight:251.32DDX3-IN-2
CAS:<p>DDX3-IN-2 is a potent DDX3 inhibitor with an IC50 of 0.3 μM and shows broad antiviral effects, including against HIV resistance.</p>Formula:C20H23N5OColor and Shape:SolidMolecular weight:349.43ARV-393
CAS:<p>ARV-393 is a PROTAC degrader targeting BCL6 orally available. ubiquitin proteasome for diffuse large b-cell lymphoma (DLBCL) and non-Hodgkin's lymphoma (NHL)</p>Formula:C46H53ClFN9O7Purity:99.96%Color and Shape:SoildMolecular weight:898.42KIN1400
CAS:<p>KIN1400 activates IRF3, boosts antiviral immunity, stimulates IFNbeta, and inhibits WNV, DV, and HCV.</p>Formula:C24H17F2N3O2SPurity:98%Color and Shape:SolidMolecular weight:449.47SNAP 398299
CAS:<p>SNAP 398299 is a Glycopeptide Receptor Type 3 (Gal3) antagonist with anxiolytic and antidepressant-like effects and is used in the study of mood disorders.</p>Formula:C27H24F3N3O2Purity:97.16%Color and Shape:SolidMolecular weight:479.49GCPII-IN-1 TFA
CAS:<p>GCPII-IN-1 TFA (compound 2) is an inhibitor scaffold for glutamate carboxypeptidase II (GCPII, PSMA) with a Ki of 44.3±2.4 nM for use in prostate cancer.</p>Formula:C14H22F3N3O9Color and Shape:SoildMolecular weight:433.34NLRP3-IN-13
CAS:<p>NLRP3-IN-13 is an NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study of neurological disorders and inflammation.</p>Formula:C19H15N3O3SPurity:99.16%Color and Shape:SolidMolecular weight:365.41MitoTEMPOL
CAS:<p>MitoTEMPOL is a mitochondria-targeted antioxidant that prevents septal dysfunction by reversing sepsis-induced decreases in mitochondrial function.</p>Formula:C32H42BrNO2PColor and Shape:SolidMolecular weight:583.56ADU-S100 ammonium salt
CAS:<p>ADU-S100 ammonium salt is an activator of stimulator of interferon genes (STING).Cost-effective and quality-assured.</p>Formula:C20H30N12O10P2S2Purity:98%Color and Shape:SolidMolecular weight:724.6LY 178002
CAS:<p>LY 178002 inhibits 5-LPO (IC50: 0.6 μM), PLA2, and LTB4 production; weak on cyclooxygenase.</p>Formula:C18H25NO2SPurity:98%Color and Shape:SolidMolecular weight:319.46Oxyphenbutazone monohydrate
CAS:<p>Oxyphenbutazone monohydrate: Phenylbutazone derivative, anti-inflammatory, non-selective COX inhibitor, kills dormant M. tuberculosis.</p>Formula:C19H22N2O4Color and Shape:SolidMolecular weight:342.39CU-76
CAS:<p>CU-76 inhibits cGAS (IC50 = 0.24 μM) affecting DNA-induced IFN-β production, not RIG-I-MAVS pathway, in THP-1 cells.</p>Formula:C11H8F2IN5O2Color and Shape:SolidMolecular weight:407.11MSU38225
CAS:<p>MSU38225, an Nrf-2 inhibitor, elevates reactive oxygen species (ROS) levels and suppresses the proliferation of human lung cancer cells.</p>Formula:C21H19N3Color and Shape:SolidMolecular weight:313.4Isofezolac
CAS:<p>Isofezolac (LM 22070), a NSAID, inhibits prostaglandin-synthetase, offering powerful anti-inflammatory and antipyretic effects.</p>Formula:C23H18N2O2Color and Shape:SolidMolecular weight:354.4MIF-IN-1
CAS:<p>MIF-IN-1 (compound 14) inhibits MIF, a cytokine linked to diseases, with pIC50 of 6.87.</p>Formula:C15H13N3O5Color and Shape:SolidMolecular weight:315.28Asperbisabolane L
<p>Asperbisabolane L, a sesquiterpenoid, combats inflammation by blocking NF-κB signaling and NO in BV-2 cells.</p>Formula:C12H14O3Color and Shape:SolidMolecular weight:206.24NF-κB/PON1-IN-1
CAS:<p>NF-κB/PON1-IN-1 (Compound 16) is an NF-κB/PON1 pathway inhibitor with antioxidant activity (IC50: 45.76 μM) and hepatoprotective activity.</p>Formula:C20H16N6O4S2Color and Shape:SolidMolecular weight:468.51TLR7/8 agonist 4
CAS:<p>TLR7/8 agonist 4 (compound 41) is a potent agonist of TLR7/8 with anti-cancer activity [1].</p>Formula:C18H24N6Color and Shape:SolidMolecular weight:324.42RI-962
CAS:<p>RI-962 is a potent and selective inhibitor of RIPK1 that protects cells from necrotic apoptosis by inhibiting RIPK1, RIPK3, and MLKL phosphorylation.</p>Formula:C28H28N6O2Purity:99.39%Color and Shape:SoildMolecular weight:480.56S-Isopropylisothiourea hydrobromide
CAS:<p>S-Isopropylisothiourea hydrobromide is an iNOS inhibitor.</p>Formula:C4H11BrN2SPurity:98%Color and Shape:SolidMolecular weight:199.11Antiviral agent 14
CAS:<p>Antiviral agent 14 is an antiviral agent that inhibits tobacco mosaic virus (TMV) (EC50: 135.5 μg/mL), and cucumber mosaic virus (CMV) (EC50: 178.6 μg/mL).</p>Formula:C24H26O7Color and Shape:SolidMolecular weight:426.46Ophthalmic acid
CAS:<p>Ophthalmic acid is a glutathione analog in which cysteine is substituted by L-aminobutyrate.</p>Formula:C11H19N3O6Color and Shape:SolidMolecular weight:289.29Ferric citrate
CAS:<p>Ferric citrate as a source of iron used in cell culture applications can provide iron with a less toxic form compared to free iron salts.</p>Formula:C6H8FeO7Color and Shape:Limit Its Spread To The Environment It Is Used In Medicine In Making Blueprints And As A FeedMolecular weight:247.968Ro 106-9920
CAS:<p>Inhibitor of NF-κB activation</p>Formula:C10H7N5OSPurity:98%Color and Shape:SolidMolecular weight:245.26
