Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(79 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3045 products of "Immunology and Inflammation"
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Galectin-3-IN-1
CAS:<p>Galectin-3-IN-1 is a potent Gal-3 inhibitor, key in cancer-related metabolic processes.</p>Formula:C18H26O10SColor and Shape:SolidMolecular weight:434.46Imupedone
CAS:<p>Imupedone (LF 1695) is a synthetic immunomodulator that increases the proliferative response of lymphocytes to mitogens, antigens and allogeneic cells.</p>Formula:C19H21ClN2OPurity:99.53%Color and Shape:SolidMolecular weight:328.84DPP-4 inhibitor 3
CAS:<p>DPP-4 inhibitor 3 is a powerful DPP-IV blocker with 0.75 nM IC50, boasting antioxidant and insulinotropic effects.</p>Formula:C19H22N6O2Color and Shape:SolidMolecular weight:366.42NIC-0102
CAS:<p>NIC-0102 is an orally active proteasome inhibitor (pIC50:7.55) that exhibits specific inhibition of NLRP3 inflammatory vesicle activation. Inhibitory effect.</p>Formula:C21H25BF2N2O4Color and Shape:SolidMolecular weight:418.24Naproxcinod
CAS:<p>Naproxcinod is a derivative of naproxen, analgesic and anti-inflammatory, a COX-inhibitory nitric oxide donor (CINOD), osteoarthritis and inflammatory.</p>Formula:C18H21NO6Color and Shape:SolidMolecular weight:347.36MIP-1095
CAS:<p>MIP-1095 is the prostate-specific membrane antigen inhibitor.</p>Formula:C19H25IN4O8Purity:98%Color and Shape:SolidMolecular weight:564.33COX-2-IN-28
CAS:<p>COX-2-IN-28 is a potent and selective COX-2 inhibitor capable of acting on COX-2 (IC50: 0.054 μM), 15-LOX (IC50: 2.14 μM) and COX-1 (IC50: 13.21 μM).</p>Formula:C30H27N7S3Color and Shape:SolidMolecular weight:581.78AP-1/NF-κB activation inhibitor 1
CAS:<p>AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basal</p>Formula:C13H11F3N4O4Purity:99.52% - 99.91%Color and Shape:SolidMolecular weight:344.25BCX 1470
CAS:<p>BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.</p>Formula:C14H10N2O2S2Purity:98%Color and Shape:SolidMolecular weight:302.37STING Agonist C11
CAS:<p>STING agonist C11 activates STING, induces type I IFN in cells, phosphorylates IRF3, and lowers various viral titers via STING/IFNAR pathway.</p>Formula:C19H18N4O3SColor and Shape:SolidMolecular weight:382.44CD73-IN-9
CAS:<p>CD73-IN-9, a potent inhibitor of CD73, may treat cancer by blocking adenosine production that aids tumor growth and spread.</p>Formula:C14H11F2N5O2Color and Shape:SolidMolecular weight:319.27Heme Oxygenase-1-IN-1 hydrochloride
CAS:<p>HO-1-IN-1 hydrochloride is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM).</p>Formula:C13H16BrClN2Color and Shape:SolidMolecular weight:315.64IACS-8803
CAS:<p>IACS-8803 is a potent cyclic dinucleotide STING agonist that exhibits strong systemic antitumor efficacy.</p>Formula:C20H23FN10O9P2S2Purity:98%Color and Shape:SolidMolecular weight:692.53L-Nabe
CAS:<p>L-Nabe (H-Arg(NO2)-Obzl) is a effective irreversible endothelium dependent relaxation inhibitor.</p>Formula:C13H19N5O4Purity:98.03%Color and Shape:SolidMolecular weight:309.32ML388
CAS:<p>ML388 is an inhibitor of human NAD(+)- dependent 15- hydroxyprostaglandin dehydrogenase.</p>Formula:C20H24N4Purity:98%Color and Shape:SolidMolecular weight:320.43BSP16
CAS:<p>BSP16: potent, oral STING agonist; boosts interferon genes; promising for cancer research.</p>Formula:C16H18O5SeColor and Shape:SolidMolecular weight:369.27TL8-506
CAS:<p>TL8-506 is a selective and potent TLR8 agonist that induces cytokine and chemokine production.TL8-506 alleviates inflammatory and autoimmune diseases.</p>Formula:C20H17N3O2Purity:95% - 99.97%Color and Shape:SolidMolecular weight:331.37Naproxen etemesil
CAS:<p>Naproxen, a COX-1/2 inhibitor, has IC50s of 8.72/5.15 μM. Its prodrug, naproxen etemesil, is lipophilic and converts to active form upon absorption.</p>Formula:C17H20O5SPurity:98%Color and Shape:SolidMolecular weight:336.4IL-17A modulator-3
CAS:<p>IL-17A modulator-3 inhibits IL-17A/A, IC50 <10 μM, for inflammation, cancer, autoimmune research.</p>Formula:C34H50FN7O4Color and Shape:SolidMolecular weight:639.86,2',4'-Trimethoxyflavone
CAS:<p>The compound is an Aryl hydrocarbon receptor antagonist (EC50 = 0.9 μM). It also has no short term agonist activity and no species or promoter dependence.</p>Formula:C18H16O5Purity:98%Color and Shape:SolidMolecular weight:312.32MIF degrader MD13
CAS:<p>MD13, a MIF-degrading PROTAC, disrupts vital protein interactions in cancer and inflammation, showing promise as a therapeutic research tool.</p>Formula:C35H35N5O8Color and Shape:SolidMolecular weight:653.68TFC-007
CAS:<p>TFC-007 is an H-PGDS inhibitor, reducing inflammation, useful for studying guinea pig allergic rhinitis induced by cedar pollen.</p>Formula:C27H29N5O4Purity:98.07%Color and Shape:SolidMolecular weight:487.55PD 127443
CAS:<p>PD 127443 is a Leukotriene B4 antagonist, it is also a dual inhibitor of cyclooxygenase and 5-lipoxygenase.</p>Formula:C20H28N2OColor and Shape:SolidMolecular weight:312.45CU-32
CAS:<p>CU-32 is a cGAS inhibitor with IC50=0.45 μM, blocks DNA-stimulated IFN-β production, and is selective over RIG-I-MAVS and TLRs pathways.</p>Formula:C11H10IN5O2Color and Shape:SolidMolecular weight:371.13ASP-6537
CAS:<p>ASP-6537 is a selective and reversible inhibitor of cyclooxygenase-1.</p>Formula:C17H17N3O3Purity:98%Color and Shape:SolidMolecular weight:311.34Carpro-AM1
CAS:<p>Carpro-AM1, dual FAAH/COX inhibitor, IC50: 94 nM.</p>Formula:C21H18ClN3OColor and Shape:SolidMolecular weight:363.84COX-2-IN-11
CAS:<p>COX-2-IN-11 (compound 7b2) is a potent and selective COX-2 inhibitor. COX-2-IN-11 has the potential in inflammation disease research[1].</p>Formula:C12H12OS3Color and Shape:SolidMolecular weight:268.42MLT-747
CAS:MLT-747 is an effective and allosteric inhibitor of MALT1. It binds MALT1 in the allosteric Trp580 pocket (IC50: 14 nM).Formula:C20H21Cl2N7O3Color and Shape:SolidMolecular weight:478.33Xanthine oxidase-IN-6
<p>Xanthine oxidase-IN-6: potent oral mixed-type XOD inhibitor, IC50 1.37 µM, anti-hyperuricemia, renal protection.</p>Formula:C29H34N2O15Color and Shape:SolidMolecular weight:650.58NED-3238
CAS:<p>NED-3238 is a highly potent inhibitor of arginase I and II (IC50 of 1.3 nM and 8.1 nM, respectively).</p>Formula:C17H28BN3O4Purity:98%Color and Shape:SolidMolecular weight:349.23AR-C102222 hydrochloride
CAS:AR-C102222 hydrochloride: oral iNOS inhibitor, selective, IC50=37 nM, with anti-inflammatory and pain relief effects.Formula:C19H17ClF2N6OPurity:98%Color and Shape:SolidMolecular weight:418.83Mivotilate
CAS:<p>Mivotilate, a potent, non-toxic aryl hydrocarbon receptor (AhR) activator, functions as a hepatoprotective agent.</p>Formula:C12H14N2O3S3Purity:98%Color and Shape:SolidMolecular weight:330.45AMT hydrochloride
CAS:<p>AMT hydrochloride is an iNOS inhibitor.</p>Formula:C5H11ClN2SPurity:98%Color and Shape:SolidMolecular weight:166.67Cyclic-di-GMP
CAS:<p>Cyclic-di-GMP is a STING agonist and ubiquitous second messenger, which regulates the formation, motility and virulence of biofilms in various bacterial species</p>Formula:C20H24N10O14P2Purity:98%Color and Shape:SolidMolecular weight:690.41STING Agonist 12b
CAS:<p>STING agonist 12b activates human/mouse STING, binds with Kd 26.4 μM, prompts interferon, and induces TNF-a, IL-6, IP-10, IL-1b in THP-1 cells.</p>Formula:C16H15NO2Color and Shape:SolidMolecular weight:253.3CD73-IN-8
CAS:<p>CD73-IN-8 blocks CD73, hindering adenosine production that supports tumor growth, flagged as compound 57 in WO2022052886A1.</p>Formula:C17H13ClN4O2Color and Shape:SolidMolecular weight:340.76IRAK4-IN-16
CAS:<p>IRAK4-IN-16 inhibits IRAK4 at 2.5nM; cytotoxic to OCI-LY10, TMD8, Ramos, HT cells with IC50s of 0.2, 0.2, 0.6, 2.7μM.</p>Formula:C17H20F2N8OColor and Shape:SolidMolecular weight:390.39L-NIL hydrochloride
CAS:<p>selective inhibitor of inducible nitric oxide synthase</p>Formula:C8H18ClN3O2Purity:98%Color and Shape:White To Off-White SolidMolecular weight:223.7IRAK inhibitor 4
CAS:<p>IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4 inhibitor.</p>Formula:C33H35F3N6O3Purity:98%Color and Shape:SolidMolecular weight:620.66AL-8417
CAS:<p>AL-8417 is an enzyme inhibitor with antioxidant, anti-inflammatory, and cytostatic properties; prevents vitrectomy-induced lens alterations.</p>Formula:C29H34O5Purity:98%Color and Shape:SolidMolecular weight:462.58Mercaptoethylguanidine (MEG) (dihydrobromide)
CAS:<p>MEG dihydrobromide inhibits inducible nitric oxide synthase and scavenges peroxynitrite, potentially aiding in inflammatory bowel disease studies.</p>Formula:C3H11Br2N3SColor and Shape:SolidMolecular weight:281.01Sulfo-ara-F-NMN
CAS:<p>Sulfo-ara-F-NMN: cell-permeable, NMN analogue, activates SARM1, inhibits CD38 (IC50 ~10μM), induces cADPR, NAD loss, non-apoptotic death.</p>Formula:C11H14FN2O6PSPurity:98%Color and Shape:SolidMolecular weight:352.28MD13
<p>MD13 is a macrophage migration inhibitor (MIF) oriented PROTAC (Ki value: 71 nM). MD13 can be used to study cancer.</p>Color and Shape:LiquidCOX-2-IN-18
CAS:<p>COX-2-IN-18 is a potent COX-2 inhibitor similar to Celecoxib, showing promise in cancer research. IC50=0.775μM.</p>Formula:C18H19N3O3S2Color and Shape:SolidMolecular weight:389.49(R)-MLT-985
CAS:<p>(R)-MLT-985 (compound 11) is a MALT1 protease inhibitor with IC50 of 3 nM, also blocking IL-2 in Jurkat cells and ABC-DLBCL cell growth.</p>Formula:C17H15Cl2N9O2Color and Shape:SolidMolecular weight:448.27TPO agonist 1
CAS:<p>TPO agonist 1 is a thrombopoietin agonist. It would be useful as promoters of thrombopoiesis and megakaryocytopoiesis to treat thrombocytopenia.</p>Formula:C25H22N8O2Purity:98%Color and Shape:SolidMolecular weight:466.49Dihydrolipoic acid
CAS:<p>Dihydrolipoic acid (USAF XR-12), a dithiol carboxylic acid, is a potent antioxidant active against various reactive oxygen species at 0.01-0.5 mM.</p>Formula:C8H16O2S2Purity:97.51%Color and Shape:Yellow To Orange LiquidMolecular weight:208.34Methyl aminolevulinate
CAS:<p>Methyl aminolevulinate, a prodrug for protoporphyrin IX, sensitizes in PDT.</p>Formula:C6H11NO3Purity:98%Color and Shape:SolidMolecular weight:145.16NF-κB-IN-2
CAS:<p>NF-κB-IN-2 inhibits canonical NF-κB signaling induced by TNF-α in PC-3 cells.</p>Formula:C15H18O3Color and Shape:SolidMolecular weight:246.3Clopirac
CAS:<p>Clopirac is a potent and orally active prostaglandin synthetase inhibitor that is an anti-inflammatory agent [1].</p>Formula:C14H14ClNO2Color and Shape:SolidMolecular weight:263.72
