Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(79 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
Show 11 more subcategories
Found 3045 products of "Immunology and Inflammation"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
IRAK4-IN-17
CAS:<p>IRAK4-IN-17 is a potent IRAK4 inhibitor with a 1.3 nM IC50, key for DLBCL research.</p>Formula:C17H20F2N8OColor and Shape:SolidMolecular weight:390.39HPGDS inhibitor 3
CAS:<p>HPGDS inhibitor 3: oral, potent (IC50=9.4 nM; EC50=42 nM), selective, no CNS toxicity, good pharmacokinetics, anti-inflammatory.</p>Formula:C21H27N3O2Color and Shape:SolidMolecular weight:353.46OPC-163493
CAS:<p>OPC-163493 is an orally active, liver-targeted mitochondrial uncoupling agent that diminishes Δψ (delta psi) and mitochondrial ROS (reactive oxygen species)</p>Formula:C14H8F3N5SPurity:98%Color and Shape:SolidMolecular weight:335.31L-Kynurenine sulfate
CAS:<p>L-Kynurenine sulfate activates AHR, leading naive T cells to anti-inflammatory Treg phenotype.</p>Formula:C10H14N2O7SColor and Shape:SolidMolecular weight:306.29STING modulator-4
CAS:STING modulator-4: competitive, Ki=0.0933 μM (R232H STING), EC50 >10 μM (p-IRF3, THP-1 cells).Formula:C17H18N8OColor and Shape:SolidMolecular weight:350.38BC12-4
CAS:<p>BC12-4 is a novel potent inhibitor of IL-2 secretion, it has potent immunomodulatory activity.</p>Formula:C19H14N2O3Color and Shape:SolidMolecular weight:318.33c-di-AMP
CAS:<p>c-di-AMP (Cyclic diadenylate) is a STING agonist. It binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway.</p>Formula:C20H24N10O12P2Purity:98%Color and Shape:SolidMolecular weight:658.41Keap1-Nrf2-IN-13
CAS:<p>Keap1-Nrf2-IN-13 is a PPI inhibitor (IC50: 0.15 μM) that binds Keap1 strongly, useful for oxidative stress and inflammation research.</p>Formula:C28H32N2O10S2Color and Shape:SolidMolecular weight:620.69C5aR-IN-2
CAS:<p>C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.</p>Formula:C36H40FN5O2Color and Shape:SolidMolecular weight:593.73COX-2-IN-20
CAS:<p>COX-2-IN-20 (Compound 5d) is a selective and orally active inhibitor of COX-2 (IC 50 = 17.9 nM) with anti-inflammatory activity [1].</p>Formula:C11H9ClFN3O2Color and Shape:SolidMolecular weight:269.66APC-0576
CAS:<p>APC-0576, an (S,S)-isomer, blocks NF-kappaB gene activation and may reduce inflammation in human cells.</p>Formula:C23H27N3O3Color and Shape:SolidMolecular weight:393.48TLR7/8 agonist 6
CAS:<p>Compound 4: Imidazoquinoline, potent TLR7/8 agonist, IC50: 0.18μM (TLR7), 5.34μM (TLR8).</p>Formula:C24H27N5O2Color and Shape:SolidMolecular weight:417.5TMV-IN-1
CAS:<p>TMV-IN-1: a chalcone inhibits TMV with EC50s of 70.7 and 60.8 μg/mL, applicable in infection and tumor studies.</p>Formula:C28H26O4Color and Shape:SolidMolecular weight:426.5PNRI-299
CAS:<p>PNRI-299 is a selective inhibitor of AP-1 transcription(IC50 of 20 uM ).</p>Formula:C21H15N5O4Purity:98%Color and Shape:SolidMolecular weight:401.37Veledimex (S enantiomer)
CAS:Veledimex S is the oral S enantiomer of a gene therapy promoter activator and CYP3A4/5 inhibitor.Formula:C27H38N2O3Purity:98%Color and Shape:SolidMolecular weight:438.6COX-2/sEH-IN-1
CAS:<p>COX-2/sEH-IN-1, oral dual inhibitor: COX-2 (IC50=1.24 μM), sEH (IC50=0.40 μM); boosts anti-inflammatory action, cuts heart risk.</p>Formula:C23H18F3N5O3SColor and Shape:SolidMolecular weight:501.48Keap1-Nrf2-IN-14
CAS:<p>Keap1-Nrf2-IN-14, a KEAP1-NRF2 inhibitor (IC50: 75 nM, Kd: 24 nM), boosts NRF2 gene expression, antioxidative and anti-inflammatory response.</p>Formula:C30H29NO8SColor and Shape:SolidMolecular weight:563.62β-Nor-lapachone
CAS:β-Nor-lapachone is an antibiofilm agent of Candida glabrata.Formula:C14H12O3Color and Shape:SolidMolecular weight:228.24COX-1/2-IN-1
CAS:<p>"COX-1/2-IN-2: Strong dual inhibitor of COX-1 (IC50 = 13.9 μM) and COX-2 (IC50 = 6.4 μM)."</p>Formula:C15H10BrClN2OColor and Shape:SolidMolecular weight:349.61Z-VRPR-FMK
CAS:<p>Z-VRPR-FMK: irreversible MALT1 inhibitor, halts growth/invasion of diffused B-cell lymphoma by blocking NF-κB activation and MMP expression.</p>Formula:C31H49FN10O6Color and Shape:SolidMolecular weight:676.78COX-1/2-IN-3
CAS:<p>COX-1/2-IN-3 (Compound 7a) is a dual inhibitor of COX-1 and COX-2. COX-1/2-IN-3 has anti-inflammatory activity with low toxicity [1].</p>Formula:C14H8N2O8Color and Shape:SolidMolecular weight:332.22IFN α-IFNAR-IN-1
CAS:<p>Nonpeptidic IFN-α/IFNAR blocker, halts MVA-triggered BM-pDC IFN-α response; IC50: 2-8 μM.</p>Formula:C18H17NSPurity:98%Color and Shape:SolidMolecular weight:279.4COX-2-IN-23
CAS:<p>COX-2-IN-23 selectively inhibits COX-2 (IC50=0.28μM), weakly affects COX-1 (IC50=20.14μM), and has anti-inflammatory and low ulcerogenic properties.</p>Formula:C24H25N5O3S2Color and Shape:SolidMolecular weight:495.62IRAK4-IN-13
CAS:<p>IRAK4-IN-13 (compound 21) is a potent IRAK4 inhibitor, IC50 0.6 nM, with high HLM clearance at 96 μL/min/mg.</p>Formula:C24H27N9OColor and Shape:SolidMolecular weight:457.53PPM-18
CAS:<p>PPM-18 (NSC 73233), a potent anti-inflammatory, inhibits iNOS and NF-κB binding; also suppresses bladder cancer cell growth.</p>Formula:C17H11NO3Color and Shape:SolidMolecular weight:277.27COX-2-IN-24
CAS:<p>COX-2-IN-24 is an orally active COX-2 inhibitor (IC50: 0.17 μM) with anti-inflammatory and hypo-ulcerogenic effects.</p>Formula:C24H24BrN5O3S2Color and Shape:SolidMolecular weight:574.51COX-2-IN-19
CAS:<p>COX-2-IN-19, a potent COX-2 inhibitor, IC50 of 1.76 μM, has strong anti-inflammatory effects in vivo.</p>Formula:C18H18N4O2SColor and Shape:SolidMolecular weight:354.43CAY10589
CAS:<p>CAY10589 is an mPGES-1 inhibitor.</p>Formula:C25H28ClN3O2SColor and Shape:SolidMolecular weight:470.03DMX-129
CAS:<p>DMX-129 is a chemical compound acting as an inhibitor for both ΙΚΚε and TBK-1, demonstrating efficacy with IC50 values of below 30 nM for each [1].</p>Formula:C19H17FN8Color and Shape:SolidMolecular weight:376.39COX-2/5-LOX-IN-2
CAS:<p>COX-2/5-LOX-IN-2, a benzothiophen derivative, inhibits COX-1, COX-2, 5-LOX with IC50s of 5.40, 0.01, 1.78 μM. More effective than Celecoxib, Indomethacin.</p>Formula:C18H13N3O4S2Color and Shape:SolidMolecular weight:399.44PT4
CAS:<p>PT4: treats CL, disrupts parasite mitochondria, kills Leishmania spp., IC50- L. amazonensis 125.18 μM, L. braziliensis 233.18 μM, anti-inflammatory.</p>Formula:C18H14N4O2Color and Shape:SolidMolecular weight:318.33P2X7-IN-2
CAS:<p>P2X7-IN-2 is a P2X7 receptor blocker, halts IL-Iβ release (IC50: 0.01 nM), researched for autoimmunity and heart issues.</p>Formula:C22H21F4N3O2Color and Shape:SolidMolecular weight:435.41IT-901
CAS:<p>IT-901: Oral NF-κB c-Rel inhibitor, IC50 0.1 µM. Blocks c-Rel/DNA binding, IC50 3 µM. Antitumor naphthalene derivative for lymphoma/myeloma therapy.</p>Formula:C17H14N2O4SPurity:98.06%Color and Shape:SolidMolecular weight:342.37Piroxicam cinnamate
CAS:<p>Cinnoxicam is a COX inhibitor used for bone/joint inflammation, rheumatic issues, and varicocele-related oligospermia.</p>Formula:C24H19N3O5SColor and Shape:SolidMolecular weight:461.49Keap1-Nrf2-IN-12
CAS:<p>eap1-Nrf2-IN-12 is a potent inhibitor of Keap1-Nrf2 (IC50: 2.30 μM). eap1-Nrf2-IN-12 is metabolically stable in human liver microsomes.</p>Formula:C26H28N2O10S2Color and Shape:SolidMolecular weight:592.64APHS
CAS:<p>APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1.</p>Formula:C15H18O2SColor and Shape:SolidMolecular weight:262.37NXPZ-2
CAS:<p>NXPZ-2, an oral Keap1-Nrf2 PPI inhibitor (Ki: 95 nM, EC50: 120-170 nM), may improve cognition and neuron health in AD.</p>Formula:C27H27N5O7S2Color and Shape:SolidMolecular weight:597.6610-Cl-BBQ
CAS:<p>10-Cl-BBQ is a ligand of aryl hydrocarbon receptor (AhR).</p>Formula:C18H9ClN2OColor and Shape:SolidMolecular weight:304.73Keap1-Nrf2-IN-11
CAS:<p>Keap1-Nrf2-IN-11 (6k) inhibits Keap1-Nrf2, KD 0.21 nM; reduces ROS, NO, TNF-α; aids anti-inflammatory research.</p>Formula:C36H43N7O8S2Color and Shape:SolidMolecular weight:765.9iNOs-IN-3
CAS:<p>iNOs-IN-3: oral iNOS inhibitor, IC50 = 3.342 μM, anti-inflammatory, for LPS-induced ALI study.</p>Formula:C27H24N2O5SColor and Shape:SolidMolecular weight:488.55Antimicrobial agent-2
CAS:<p>Compound V-a: broad-spectrum, low-toxicity antimicrobial with no resistance, high bioavailability, damages membranes, targets MRSA (MIC 1μg/mL).</p>Formula:C16H14N2O4SColor and Shape:SolidMolecular weight:330.36Nrf2 activator-5
CAS:<p>Nrf2 activator-5 combats oxidative stress and inflammation in microglia, with potent antioxidant effects.</p>Formula:C25H30Cl2O6Color and Shape:SolidMolecular weight:497.41AChE/Nrf2 modulator 1
CAS:<p>AChE/Nrf2 modulator 1: oral, targets AChE/Nrf2, IC50s: 0.07 μM (eeAChE), 0.38 μM (hAChE); for Alzheimer's research.</p>Formula:C27H27FN4O2Color and Shape:SolidMolecular weight:458.53NF-κB-IN-3
CAS:<p>NF-κB-IN-3 (Compound 2) is an NF-κB inhibitor (IC50: 0.70 μM) and can be used as an anti-tumour agent.</p>Formula:C24H18ClF3N2O2Color and Shape:SolidMolecular weight:458.86COX-2-IN-21
CAS:<p>COX-2-IN-21 (Compound 5c) is an orally active, selective COX-2 inhibitor (IC50: 0.039 μM). COX-2-IN-21 has good anti-inflammatory potential.</p>Formula:C21H22N6O4Color and Shape:SolidMolecular weight:422.44HE 3286
CAS:<p>Triolex, an NF-kB inhibitor, is used potentially for the treatment of rheumatoid arthritis, ulcerative colitis.</p>Formula:C21H30O3Color and Shape:SolidMolecular weight:330.46Tilarginine citrate
CAS:<p>Tilarginine citrate is a competitive nitric oxide synthetase inhibitor.</p>Formula:C13H24N4O9Purity:98%Color and Shape:SolidMolecular weight:380.354Enflicoxib
CAS:<p>Enflicoxib is an effective treatment for canine osteoarthritis pain and inflammation, with faster onset than mavacoxib, improving veterinary outcomes.</p>Formula:C16H12F5N3O2SPurity:99.88%Color and Shape:SolidMolecular weight:405.34IRAK4-IN-22
CAS:<p>IRAK4-IN-22: oral IRAK4 inhibitor, IC50: IRAK4-3nM, TAK1-17nM, disrupts IL-23, targets autoimmune diseases.</p>Formula:C28H28FN7O2Color and Shape:SolidMolecular weight:513.57CHD-5
CAS:<p>CHD-5 is a selective antagonist of the aryl hydrocarbon receptor (AhR).</p>Formula:C19H17N3O2Color and Shape:SolidMolecular weight:319.36
