Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(79 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3045 products of "Immunology and Inflammation"
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Naproxen glucuronide
CAS:<p>Naproxen glucuronide: NSAID, propionic class, eases pain, fever, inflammation. Nonselective COX blocker.</p>Formula:C20H22O9Color and Shape:SolidMolecular weight:406.3812(R)-HETE
CAS:<p>12(R)-HETE made in invertebrates by lipoxygenation, in mammals by 12(R)-LOs/CYP450. Mainly proinflammatory, attracts leukocytes, reduces rabbit eye pressure.</p>Formula:C20H32O3Color and Shape:SolidMolecular weight:320.47Feprazone
CAS:<p>Feprazone (DA-2370) possesses anti-inflammatory and antiadipogenic properties. Feprazone can be used in studies about the treatment of joint and muscular pain.</p>Formula:C20H20N2O2Purity:99.6% - 99.89%Color and Shape:SolidMolecular weight:320.39Nexinhib20
CAS:<p>Nexinhib20 is an inhibitor of exosome synthesis and transport with anti-inflammatory activity, inhibits RAB27A and neutral sphingomyelinase 2 (nSMase2) nsMase2.</p>Formula:C15H16N4O3Purity:99.89%Color and Shape:SolidMolecular weight:300.31Leptospermone
CAS:<p>Leptospermone is an essential oil from Leptospermum scoparium (manuka oil).</p>Formula:C15H22O4Color and Shape:SolidMolecular weight:266.33Dibenzo(a,i)pyrene
CAS:<p>Dibenzo(a, i)pyrene is a polycyclic aromatic hydrocarbon with potent carcinogenic activity.</p>Formula:C24H14Color and Shape:Greenish-Yellow Needles Prisms Or Lamellae Dibenz[A I]Pyrene Is A Colorless Solid Water InsolubleMolecular weight:302.37Stigmane B
<p>Stigmane B activates Nrf2, decreases apoptosis and ROS, boosts antioxidants, and is neuroprotective.</p>Formula:C21H30O4Color and Shape:SolidMolecular weight:346.46NBC 19
CAS:<p>Potent NLRP3 inflammasome inhibitor (IC50 = 60-80 nM). Inhibits nigericin- and ATP-induced IL-1β release.</p>Formula:C24H26BCl3N2O2Color and Shape:SolidMolecular weight:491.65BBS-4
CAS:<p>BBS-4 inhibits NOS2 dimerization (IC50: 0.49 nM), guarding mice against sepsis-related heart issues.</p>Formula:C22H24N6O3Color and Shape:SolidMolecular weight:420.46MIF-IN-3
CAS:<p>MIF-IN-3 inhibits MIF; useful in immunoinflammation research. (WO2021258272A1, compound 31)</p>Formula:C20H20N4O5SColor and Shape:SolidMolecular weight:428.46CK-119
CAS:<p>CK-119 inhibits IL-1, blocking corneal/conjunctival cell growth by halting DNA/RNA synthesis.</p>Formula:C21H23ClN4O5Color and Shape:SolidMolecular weight:446.88HSR1304
CAS:<p>HSR1304 (5d) inhibits NFκB, key in diseases like cancer, offering research potential.</p>Formula:C24H21ClN2O3Color and Shape:SolidMolecular weight:420.89Anti-inflammatory agent 21
CAS:<p>Compound 9o: orally active, low-toxicity anti-inflammatory; inhibits NO (IC50: 0.76 μM), blocks NF-κB/MAPK, reduces arthritis symptoms.</p>Formula:C24H21FO6Color and Shape:SolidMolecular weight:424.42Fc 11a-2
CAS:<p>Fc 11a-2, an oral benzimidazole, potently inhibits NLRP3 inflammasome and caspase-1 to prevent colitis.</p>Formula:C16H16N2Color and Shape:SolidMolecular weight:236.31COX-2-IN-22
CAS:<p>COX-2-IN-22 inhibits COX-2 (IC50: 8.6μM) and crosses the blood-brain barrier, also affects AChE, BChE, β-Secretase, LOX-5, DPPH.</p>Formula:C29H24O7Color and Shape:SolidMolecular weight:484.5TNF-α-IN-18
CAS:<p>TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.</p>Formula:C16H7ClF2O4Purity:99.77%Color and Shape:SolidMolecular weight:336.67Simvastatin acid calcium hydrate
CAS:<p>Simvastatin (Tenivastatin) calcium hydrate is an oral HMG-CoA reductase inhibitor that reduces ROS by blocking indoxyl sulfate.</p>Formula:C25H40O6Color and Shape:SolidMolecular weight:436.28249AR-C 102222
CAS:<p>AR-C 102222 is an iNOS inhibitor.</p>Formula:C19H16F2N6OPurity:98%Color and Shape:SolidMolecular weight:382.37Indolokine A5
CAS:<p>Indolokine A5, a catabolite of L-cysteine, is a potent AhR agonist .</p>Formula:C13H8N2O3SColor and Shape:SolidMolecular weight:272.28COX-2/5-LOX-IN-3
CAS:<p>COX-2/5-LOX-IN-3 inhibits COX-2/5-LOX with IC50s: COX-1 45.73μM, COX-2 5.45μM, 5-LOX 4.33μM; promising for inflammation research.</p>Formula:C17H16ClN3O2SColor and Shape:SolidMolecular weight:361.85Pifoxime
CAS:<p>Pifoxime: a NSAID with COX-1/2 inhibition, used in anti-inflammatory treatment and neuropsychiatric studies.</p>Formula:C15H20N2O3Color and Shape:SolidMolecular weight:276.33NOD2 antagonist 1
CAS:<p>NOD2 antagonist 1 (compound 32): Selective, effective (IC50: 5.23μM), blocks MDP-induced IL-8 in THP-1, IL-6/IL-10/TNF-α in PBMCs.</p>Formula:C26H26N4O3SColor and Shape:SolidMolecular weight:474.57COX/5-LOX-IN-1
CAS:<p>Compound 6b is a potent dual inhibitor of COX/5-LOX with IC50s: 1.07μM (COX-1), 0.55μM (COX-2), 0.28μM (5-LOX) for inflammation research.</p>Formula:C18H30O3Color and Shape:SolidMolecular weight:294.43MIF-IN-6
CAS:<p>MIF-IN-6 is a potent MIF inhibitor with IC50 1.4 μM, Ki 0.96 μM, and hinders A549 cell growth.</p>Formula:C18H13ClFN5O2Color and Shape:SolidMolecular weight:385.78Interleukin 1β
CAS:<p>Interleukin 1beta is a bioactive chemical.</p>Formula:C15H28N4O5Purity:98%Color and Shape:SolidMolecular weight:344.41CYPMPO
CAS:<p>CYPMPO traps hydroxyl/superoxide radicals; decays in UV/H2O2 (15min) & hypoxanthine/xanthine (51min); outperforms DEPMPO in stability & shelf-life.</p>Formula:C10H18NO4PColor and Shape:SolidMolecular weight:247.23AZD5718
CAS:<p>AZD5718: potent FLAP inhibitor (IC50=2.0 nM), treats Coronary Artery Disease, >90% leukotriene suppression, safe in animal studies, in phase 2a trial.</p>Formula:C29H34N6O4Color and Shape:SolidMolecular weight:530.62COX-2-IN-26
CAS:<p>COX-2-IN-26: Oral, selective COX-2 inhibitor, low IC50s; anti-inflammatory with GI safety.</p>Formula:C23H21N7OS3Color and Shape:SolidMolecular weight:507.65MIF-IN-5
CAS:<p>MIF-IN-5: reversible MIF inhibitor, IC50 4.8 μM, Ki 3.3 μM.</p>Formula:C18H14FN5O2Color and Shape:SolidMolecular weight:351.33IMD-ferulic
<p>IMD-ferulic, a compound that forms covalent bonds, acts as an NF-κB modulator, enhancing the adjuvanticity of small molecule immune potentiators.</p>Formula:C36H41N7O4Color and Shape:SolidMolecular weight:635.76K-80001
CAS:<p>K-80001 is a selective RXRα ligand and a COX-1/2 inhibitor, exhibiting IC50 values of 82.9μM for RXRα, 3.4μM for COX-1, and 1.2μM for COX-2, respectively [1].</p>Formula:C20H17FO2Color and Shape:SolidMolecular weight:308.35Avanafil dibesylate
CAS:<p>Avanafil dibesylate is a PDE5 inhibitor.</p>Formula:C35H38ClN7O9S2Color and Shape:SolidMolecular weight:800.3(R)-MALT1-IN-3
CAS:<p>(R)-MALT1-IN-3 (121) inhibits MALT1 protease (IC50: 20 nM) and IL6/IL10 in OCI-LY3 (IC50: 60/40 nM).</p>Formula:C21H19F3N8O2Color and Shape:SolidMolecular weight:472.42COX-2-IN-17
CAS:<p>COX-2-IN-17 is a potent, blood-brain barrier permeable COX-2 (cyclooxygenase-2) inhibitor (IC50: 0.02 μM) with anti-inflammatory and analgesic activity.</p>Formula:C20H23ClN6O2Color and Shape:SolidMolecular weight:414.89AXC-715 trihydrochloride
CAS:<p>AXC-715 trihydrochloride is a TLR7/8 agonist used to make PD-L1 adjuvanted antibody immunocouplings.</p>Formula:C18H28Cl3N5Purity:99.74%Color and Shape:SolidMolecular weight:420.81MIF-IN-4 hydrochloride
CAS:<p>MIF-IN-4 hydrochloride inhibits MIF, a cytokine; has pIC50 of 5.01-6, affecting macrophage movement.</p>Formula:C26H29ClN6O2Color and Shape:SolidMolecular weight:493.01TML-6
CAS:<p>TML-6, an oral derivative of curcumin, may help in Alzheimer's research by targeting amyloid production and various molecular pathways.</p>Formula:C30H37NO7Purity:99.71%Color and Shape:SolidMolecular weight:523.62NPD926
CAS:<p>NPD926 is an inducer of cancel cell death.</p>Formula:C29H35ClN2O2Color and Shape:SolidMolecular weight:479.05Avenanthramide-C methyl ester
CAS:<p>Avenanthramide-C methyl ester blocks IKK/IκB phosphorylation, inhibits NF-κB, and reduces IL-6, IL-8, MCP-1 in endothelial cells (IC50 ~40 μM).</p>Formula:C17H15NO6Color and Shape:SolidMolecular weight:329.3Loxoprofenol-SRS tromethamine
CAS:<p>Loxoprofenol-SRS tromethamine (HR1405-01), a metabolite of Loxoprofen, is a safe IV NSAID with strong anti-inflammatory and pain relief properties.</p>Formula:C19H31NO6Color and Shape:SolidMolecular weight:369.453-OH-Kynurenamine dihydroiodide
CAS:<p>3-OH-Kynurenamine dihydroiodide, the dihydroiodide form of 3-OH-Kynurenamine, functions as an activator of the aryl hydrocarbon receptor (AhR), thereby modulating the immune response. It enhances the expression of Ido1 and Tgfb1, reducing skin inflammation in psoriasis mouse models and kidney damage in nephrotoxic lupus mouse models .</p>Formula:C9H14I2N2O2Color and Shape:SolidMolecular weight:436.03NLRP3-IN-25
CAS:<p>NLRP3-IN-25 (compound 32), an orally available NLRP3 inhibitor, exhibits anti-inflammatory properties by attenuating renal injury in a mouse model of doxorubicin-induced glomerulonephritis and inhibiting IL-1β secretion in THP-1 cells, with an IC 50 value of 21 nM [1].</p>Formula:C17H19F3N4O5SColor and Shape:SolidMolecular weight:448.42IKK2-IN-4
CAS:<p>IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.</p>Formula:C12H11N3O2SPurity:>99.99%Color and Shape:SolidMolecular weight:261.3L-NMMA acetate
CAS:<p>L-NMMA acetate inhibits all NOS types (nNOS, eNOS, iNOS); Ki: 0.18, 0.4, 6 µM respectively.</p>Formula:C9H20N4O4Purity:99.72% - 99.8%Color and Shape:White To Off-White SolidMolecular weight:248.281-Dehydro-[10]-gingerdione
CAS:<p>1-Dehydro-[10]-gingerdione blocks IKKβ, curbs IκBα phosphorylation, halts NF-κB activity, and aids inflammation research.</p>Formula:C21H30O4Color and Shape:SolidMolecular weight:346.46Naphazoline
CAS:<p>Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity.</p>Formula:C14H14N2Purity:99.79%Color and Shape:White Crystalline Powder SolidMolecular weight:210.27Safrole oxide
CAS:<p>Safrole oxide inhibits neuronal growth, induces apoptosis, elevates COX-2, IL-8, ROS, promoting endothelial-to-neuron-like cell transdifferentiation.</p>Formula:C10H10O3Purity:100%Color and Shape:SolidMolecular weight:178.18Vidarabine phosphate
CAS:<p>Vidarabine phosphate is an adenosine monophosphate analog.</p>Formula:C10H14N5O7PPurity:99.75%Color and Shape:White Crystalline PowderMolecular weight:347.22APY0201
CAS:<p>APY0201: potent, specific ATP-competitive PIKfyve inhibitor; IC50=5.2 nM; blocks PtdIns3P to PtdIns(3,5)P2 conversion.</p>Formula:C23H23N7OPurity:98% - 99.74%Color and Shape:SolidMolecular weight:413.48TYT-1
CAS:<p>TYT-1 is a West Nile virus (WNV) inhibitor, antiviral (IC₅₀ = 0.7 mM) by blocking the pre-assembly replication step following viral entry into cells.</p>Formula:C21H17N3O2S3Purity:98.49%Color and Shape:SolidMolecular weight:439.57
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