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Immunology and Inflammation

Immunology and Inflammation

Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.

Subcategories of "Immunology and Inflammation"

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Found 3055 products of "Immunology and Inflammation"

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  • 6,2′,4′-Trimethoxyflavone
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    6,2′,4′-Trimethoxyflavone

    CAS:
    <p>6,2′,4′-Trimethoxyflavone is an AhR antagonist that does not demonstrate effective protection against ischemia-reperfusion injury in the brain of Sprague-Dawley rats.</p>
    Formula:C18H18O5
    Color and Shape:Solid
    Molecular weight:314.332

    Ref: TM-T206907

  • Indeno[1,2,3-cd]pyrene
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    Indeno[1,2,3-cd]pyrene

    CAS:
    <p>Indeno[1,2,3-cd]pyrene, a polycyclic aromatic hydrocarbon, exhibits moderate cytotoxicity to human alveolar epithelial cells (HPAEpiC). Additionally, it enhances allergic pulmonary inflammation responses through the activation of the aryl hydrocarbon receptor.</p>
    Formula:C22H12
    Color and Shape:Solid
    Molecular weight:276.33

    Ref: TM-T201817

  • NLRP3-IN-57
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    NLRP3-IN-57

    <p>NLRP3-IN-57 (compound 5) inhibits the NLRP3 inflammasome, consequently downregulating IL-1β levels in THP-1 macrophages induced by LPS+Nigericin.</p>
    Formula:C44H60O7
    Color and Shape:Solid
    Molecular weight:700.94

    Ref: TM-T201467

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    COX-2/NO-IN-1

    <p>COX-2/NO-IN-1: oral iNOS &amp; NO blocker (IC50=3.52μM), COX-2 supressor, anti-inflammatory, protects kidneys.</p>
    Formula:C15H15NO3
    Color and Shape:Solid
    Molecular weight:257.28

    Ref: TM-T60403

  • NIK-IN-2
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    NIK-IN-2

    CAS:
    <p>NIK-IN-2 (compound 1) is an effective inhibitor of NF-κB inducing kinase (NIK), exhibiting a pIC50 of 7.4. It plays a crucial role in cancer research.</p>
    Formula:C20H22N4O3
    Color and Shape:Solid
    Molecular weight:366.41

    Ref: TM-T201462

  • Methoxyurea
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    Methoxyurea

    CAS:
    <p>Methoxyurea (Compound 3) is a potential modulator of nitric oxide (NO) donors, interacting with hemoglobin forms such as oxyhemoglobin (OxyHb) and methemoglobin (MetHb). It holds promise for use in research on sickle cell disease (SCD).</p>
    Formula:C2H6N2O2
    Color and Shape:Solid
    Molecular weight:90.081

    Ref: TM-T206073

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    Anti-inflammatory agent 10

    <p>Tilomisole-derived benzimidazole-thiazole, orally active, favors COX-2 inhibition over COX-1.</p>
    Formula:C17H13BrN4O3S2
    Color and Shape:Solid
    Molecular weight:465.34

    Ref: TM-T62967

  • DPP4-In hydrochloride
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    DPP4-In hydrochloride

    CAS:
    <p>DPP4-In (hydrochloride) is an inhibitor of dipeptidyl peptidase 4 (DPP4) that effectively reduces the expression of DPP4.</p>
    Formula:C14H21ClN4O2
    Color and Shape:Solid
    Molecular weight:312.8

    Ref: TM-T201441

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    XO/COX/LOX-IN-1

    <p>XO/COX/LOX-IN-1 targets XO/COX/LOX, used in research of inflammation, cancer, and metabolic disorders.</p>
    Formula:C24H20N4O2S
    Color and Shape:Solid
    Molecular weight:428.51

    Ref: TM-T62350

  • meso-Zeaxanthin
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    meso-Zeaxanthin

    CAS:
    <p>meso-Zeaxanthin accumulates in the central retina and, together with lutein and zeaxanthin, forms the macular pigment, which functions as a light filter. meso-Zeaxanthin can quench reactive oxygen species (ROS), thereby exhibiting antioxidant properties.</p>
    Formula:C40H56O2
    Color and Shape:Solid
    Molecular weight:568.871

    Ref: TM-T204572

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    CD73-IN-12

    <p>CD73-IN-12, a compound from CN114437038A, shows strong anti-tumor activity by effectively inhibiting CD73 enzyme.</p>
    Formula:C17H14F2N4O2
    Color and Shape:Solid
    Molecular weight:344.32

    Ref: TM-T61118

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    COX-2-IN-7

    <p>COX-2-IN-7: potent, orally active COX-2 inhibitor with higher selectivity than Celecoxib, IC50 6.585 uM, anti-inflammatory, low ulcer risk.</p>
    Formula:C15H13N3O2S2
    Color and Shape:Solid
    Molecular weight:331.41

    Ref: TM-T60978

  • Numidargistat
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    Numidargistat

    CAS:
    <p>CB-1158 is a potent and orally bioavailable inhibitor of arginase (IC50s: 86 and 296 nM for recombinant human arginase 1 and 2).</p>
    Formula:C11H22BN3O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:287.12

    Ref: TM-T10692L

  • RGT-068A
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    RGT-068A

    CAS:
    <p>RGT-068A is a potent, selective and oral bioavailable MALT1 inhibitor .</p>
    Formula:C17H16ClN9O2
    Color and Shape:Solid
    Molecular weight:413.82

    Ref: TM-T73389

  • NOTA-FAPI
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    NOTA-FAPI

    CAS:
    <p>NOTA-FAPI is a FAP inhibitor and FAPI-4 analogue used in PET imaging and targeted therapy for FAP-overexpressing pathological conditions.</p>
    Formula:C36H47F2N9O8
    Purity:99.748%
    Color and Shape:Solid
    Molecular weight:771.81

    Ref: TM-T69660

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    ABZI

    CAS:
    <p>(S)-2-(1-Ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1-(2-hydroxy-2-phenylethyl)-1H-benzo[d]imidazole-5-carboxamide (compound 4) is a STING agonist containing the crucial amide benzimidazole (ABZI) component. It consistently inhibits the binding of 3 H-cGAMP to STING, with an apparent inhibition constant (IC50) of 14 μM. This compound is applicable in tumor research.</p>
    Formula:C23H24N6O3
    Molecular weight:432.48

    Ref: TM-T207188

  • AMC-04
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    AMC-04

    CAS:
    AMC-04 is a protein response (UPR) activator that initiates the UPR pathway via ROS and p38 MAPK signaling, leading to apoptotic cell death. It is used in cancer research [1].
    Formula:C26H28N2O3
    Color and Shape:Solid
    Molecular weight:416.51

    Ref: TM-T85643

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    MAO-B-IN-7

    <p>MAO-B-IN-7 inhibits MAO-B/AChE, crossing the blood-brain barrier; IC50: 41/87 nM (h/eel AChE), 0.3 μM (MAO-B). Reduces oxidative stress and neuroinflammation.</p>
    Formula:C25H31NO4
    Color and Shape:Solid
    Molecular weight:409.52

    Ref: TM-T62062

  • C5aR-IN-3
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    C5aR-IN-3

    CAS:
    <p>C5aR-IN-3, a potent C5aR inhibitor, may treat autoimmune and inflammatory diseases.</p>
    Formula:C36H40FN5O3
    Color and Shape:Solid
    Molecular weight:609.73

    Ref: TM-T73262

  • (Rel)-Factor B-IN-5
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    (Rel)-Factor B-IN-5

    CAS:
    <p>(Rel)-Factor B-IN-5 is a complement factor B inhibitor that can be used to study diseases associated with activation of the alternative complement pathway.</p>
    Formula:C27H32N2O4
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:448.55

    Ref: TM-T62689