Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(140 products)
- CXCR(153 products)
- Cell wall(5 products)
- IL Receptor(109 products)
- IκB/IKK(59 products)
- LTR(3 products)
- MALT(25 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(446 products)
- NOD(17 products)
- NOS(62 products)
- Nrf2(82 products)
- PGE Synthase(31 products)
- ROS(70 products)
- TGF-beta/Smad(59 products)
- TLR(76 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3304 products of "Immunology and Inflammation"
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NLRP3 modulators 1
CAS:<p>Compound 107 (WO2017184746A1) is a potent NLRP3 modulator, useful for studying diseases linked to NLRP3 activity.</p>Formula:C17H18N6OColor and Shape:SolidMolecular weight:322.372PROTAC IRAK4 degrader-6
CAS:PROTAC IRAK4 degrader-6, potent, targets Cereblon to degrade IRAK4, detailed in US20190192668A1.Formula:C42H41F3N12O8Color and Shape:SolidMolecular weight:898.861Coltuximab
Coltuximab is a humanized anti-CD19 antibody that can be used to synthesize ADC compounds (Coltuximab Ravtansine).Purity:95.3% (SDS-PAGE); 98.6% (SEC-HPLC) - 95.3% (SDS-PAGE); 98.6% (SEC-HPLC)Color and Shape:Odour LiquidSjDX5-271
CAS:<p>SjDX5-271 is a 3 kDa peptide that inhibits the TLR4/MyD88/NF-κB signaling pathway. It induces cell polarization, alleviates liver inflammation, and protects mice from liver ischemia-reperfusion injury.</p>Formula:C137H215N47O49SColor and Shape:SolidMolecular weight:3336.52ABTIM3-hum03
<p>ABTIM3-hum03 is a humanized anti-TIM3 blood-brain barrier shuttling monoclonal antibody.</p>Purity:97.6% (SDS-PAGE); 98.6% (SEC-HPLC) - 97.6% (SDS-PAGE); 98.6% (SEC-HPLC)Color and Shape:Odour LiquidPROTAC IRAK4 degrader-2
CAS:PROTAC IRAK4 degrader-2 reduces IRAK4 in PBMCs with a DC50 of 36 nM and inhibits cytokines.Formula:C57H68FN11O8SColor and Shape:SolidMolecular weight:1086.28Nemvaleukin alfa
CAS:<p>Nemvaleukin alfa (ALKS 4230) is an interleukin 2 fusion protein that is a selective agonist of the medium-affinity IL-2 receptor.</p>Purity:98.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 98.4% (SDS-PAGE); 98.3% (SEC-HPLC)Color and Shape:LiquidNBD peptide
CAS:<p>NBD peptide inhibits the NF-κB signaling pathway by preventing the binding of the NEMO-IKK complex. It exhibits anti-inflammatory activity by blocking the production of pro-inflammatory cytokines. Additionally, NBD peptide demonstrates immunosuppressive effects through the regulation of immune cells. It enhances transmembrane capacity by conjugating with the cell-penetrating peptide HIV-TAT.</p>Formula:C62H88N14O20Color and Shape:SolidMolecular weight:1349.44(R)-Zadavotide guraxetan
CAS:<p>Zadavotide guraxetan (PSMAI&T; PNT-2002) is an inhibitor of prostate-specific membrane antigen (PSMA) with potential antitumor activity, and it is useful for research targeting prostate cancer.</p>Formula:C63H92IN11O23Color and Shape:SolidMolecular weight:1498.37Dihydrorhodamine 6G
CAS:DHR 6G, nonfluorescent reduced Rhodamine 6G, permeates cells, indicating ROS by oxidizing to fluorescent form in mitochondria.Formula:C28H32N2O3Color and Shape:SolidMolecular weight:444.57Clazakizumab
CAS:<p>Clazakizumab: monoclonal antibody targeting IL-6, may inhibit COVID-19 cytokine response, researched for PsA and renal rejection.</p>Color and Shape:LiquidC2 Ceramide (d14:1/2:0)
CAS:<p>C2 Ceramide (d14:1/2:0), a bioactive sphingolipid, causes lipotoxic cardiomyopathy when fed to Drosophila at 100 μM.</p>Formula:C16H31NO3Color and Shape:SolidMolecular weight:285.42Simlukafusp alfa
CAS:<p>Simlukafusp alfa (FAP-IL2v) is a tumor-targeting immune cytokine, a human IgG1 antibody with antitumor activity and immunostimulatory properties.</p>Purity:97.3% (SDS-PAGE); 94.3% (SEC-HPLC) - 97.3% (SDS-PAGE); 94.3% (SEC-HPLC)Color and Shape:LiquidDithianon
CAS:Dithianon: broad-spectrum anthraquinone fungicide; sticks to leaves/fruits; controls various fungi in some produce.Formula:C14H4N2O2S2Purity:98%Color and Shape:SolidMolecular weight:296.32TPNA10168
CAS:<p>Compound Fr13590, with CAS No. 957942-34-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13590 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C9H9ClO2S2Color and Shape:SolidMolecular weight:248.75AM-103 Free Acid
CAS:AM-103 Free Acid is a bio-active chemical.Formula:C36H39N3O4SColor and Shape:SolidMolecular weight:609.78Biotin-labeled ODN 1018 sodium
Biotin-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, serves as a tool for assessing cellular uptake and localization of CpG ODNs throughColor and Shape:Odour SolidPF-06426779
CAS:<p>PF-06426779 is a potent and selective inhibitor of interleukin 1 receptor associated kinase 4 (IRAK4) , with an IC 50 of 0.3 nM.</p>Formula:C17H18FN3O4Color and Shape:SolidMolecular weight:347.346iNOs-IN-6
<p>iNOs-IN-6 is an anti-inflammatory agent known for inhibiting the expression of NF-κB, iNOS, and MAPK with an IC50 ranging from 0.2 to 0.62 μM. Additionally, it decreases the levels of pro-inflammatory mediators, such as IL-6, TNF-α, and IL-1β, with an IC50 ranging from 0.4 to 0.69 μM.</p>Color and Shape:Odour SolidAmaroswerin
CAS:<p>Amaroswerin, a secoiridoid glucoside, has anti-inflammatory, antidiabetic, and other medicinal properties; it inhibits NO release at IC50 of 5.42 μg/mL.</p>Formula:C29H30O14Color and Shape:SolidMolecular weight:602.54
