Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(140 products)
- CXCR(153 products)
- Cell wall(5 products)
- IL Receptor(108 products)
- IκB/IKK(59 products)
- LTR(3 products)
- MALT(24 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(445 products)
- NOD(17 products)
- NOS(62 products)
- Nrf2(82 products)
- PGE Synthase(31 products)
- ROS(70 products)
- TGF-beta/Smad(59 products)
- TLR(74 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3269 products of "Immunology and Inflammation"
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BAY-069
CAS:<p>BAY-069 blocks BCAT1 (IC50:31 nM) & BCAT2 (IC50:153 nM), useful for cancer research.</p>Formula:C22H14ClF3N2O3Purity:99.58%Color and Shape:SoildMolecular weight:446.81Inflexuside A
CAS:Inflexuside A, an abietane diterpenoid from Isodon inflexus, and Inflexuside B inhibit NO in LPS-stimulated RAW264.7 cells.Formula:C26H42O9Color and Shape:SolidMolecular weight:498.61Lemnalol
CAS:<p>Lemnalol, from Lemnalia cervicorni, has anti-inflammatory and analgesic properties.</p>Formula:C15H24OPurity:98%Color and Shape:SolidMolecular weight:220.35FGT-4
FGT-4 is a chimeric molecule targeting folate receptor β (FR-β) and functions as a TLR7 agonist. It enhances the secretion of iNOS and the pro-inflammatory cytokine IL-6 associated with M1 macrophages and promotes the proliferation of cytotoxic CD8+ T cells. FGT-4 demonstrates antitumor activity in the 4T1 breast cancer mouse model and is applicable for cancer immunotherapy research.Formula:C50H57N11O9S2Color and Shape:SolidMolecular weight:1019.37821PSB-24000
<p>PSB-24000 (Compound 27) is a selective ecto-5'-nucleotidase (CD73) inhibitor with a Ki value of 563 nM for inhibiting human CD73, and a Ki of 481 nM in membrane-bound CD73 in triple-negative breast cancer cells. It disrupts CD73’s recognition and action on substrate AMP, preventing AMP-induced immunosuppressive and pro-cancer adenosine production. PSB-24000 is promising for cancer research.</p>Color and Shape:Odour SolidJPE-1375
CAS:JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.Formula:C49H63FN10O9Color and Shape:SolidMolecular weight:955.08G3-C12
CAS:G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.Formula:C74H115N23O23S2Purity:98%Color and Shape:SolidMolecular weight:1758.99PROTAC IRAK4 degrader-3
CAS:PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader based on von Hippel-Lindau.Formula:C57H68FN11O8SColor and Shape:SolidMolecular weight:1086.3CD73-IN-17
<p>CD73-IN-17 (compound 19) is an inhibitor of CD73 with an IC50 of 0.1 μM against hCD73. It is applicable in cancer research.</p>Color and Shape:Odour SolidLintuzumab
CAS:Lintuzumab (HuM-195) is an uncoupled humanized mouse monoclonal antibody against CD33 with anti-leukemic activity.Purity:98% (SDS-PAGE); 98.6% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.2% (SEC-HPLC)Color and Shape:Liquid2-Aminoquinoline
CAS:<p>Compound Fr16621, with CAS No. 580-22-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr16621 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C9H8N2Color and Shape:Light Yellow CrystalsMolecular weight:144.18Biotin-labeled ODN 2088 sodium
Biotin-labeled ODN 2088 (sodium) acts as a potent inhibitor of TLR3, TLR7, and TLR9.Color and Shape:Odour SolidSTING-IN-13
<p>STING-IN-13 is a selective STING inhibitor that effectively suppresses downstream signaling of the STING pathway and STING-mediated inflammation. It exhibits low toxicity and is suitable for research related to STING-associated inflammatory and autoimmune diseases.</p>Color and Shape:Odour SolidPROTAC STING degrader-3
<p>PROTACSTING degrader-3 (Compound ST9) is a STINGPROTAC-type degrader with a DC50 of 0.62 μM. It induces STING degradation via the ubiquitin-proteasome pathway. This compound exerts anti-inflammatory effects by inhibiting the STING/TBK1/NF-κB signaling. Additionally, it offers renal protection and can be used in research on acute kidney injury.</p>Color and Shape:Odour SolidSartorypyrone D
CAS:Sartorypyrone D, from N. fischeri, inhibits NFRD (1.7 μM) and NADH oxidase (3 μM), and fights Gram-positive bacteria.Formula:C26H38O4Color and Shape:SolidMolecular weight:414.586Septeremophilane E
Septeremophilane E, from Septoria rudbeckiae fungus, inhibits NO production.Formula:C21H26O5Color and Shape:SolidMolecular weight:358.43STING-IN-12
<p>STING-IN-12 (compound Y2) acts as an inhibitor of STING. It suppresses IFNβ gene expression induced by SR717 with an IC50 of 0.75 μM. Additionally, STING-IN-12 inhibits STING pathway activation induced by the STING agonist SR717 in THP1 cells and by MSA-2 in mice.</p>Color and Shape:Odour Solid2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside
CAS:<p>2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside is a chlorophenyl glycoside that is commonly found in the bulbs of</p>Formula:C20H27Cl3O12Color and Shape:SolidMolecular weight:565.78Paneolilludinic acid
CAS:Paneolilludinic acid from Cryptomarasmius aucubae fungus inhibits NO production.Formula:C15H22O3Color and Shape:SolidMolecular weight:250.33Nasunin
CAS:<p>Delphanin, also known as Nasunin, is an anthocyanin isolated as purple colored crystals from eggplant peels.</p>Formula:C42H47ClO23Color and Shape:SolidMolecular weight:955.26
