Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(140 products)
- CXCR(153 products)
- Cell wall(5 products)
- IL Receptor(109 products)
- IκB/IKK(58 products)
- LTR(2 products)
- MALT(24 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(446 products)
- NOD(17 products)
- NOS(62 products)
- Nrf2(82 products)
- PGE Synthase(31 products)
- ROS(70 products)
- TGF-beta/Smad(59 products)
- TLR(74 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3244 products of "Immunology and Inflammation"
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Sacituzumab MMAE
<p>Sacituzumab-MMAE (CHB295) Anti-TROP2 Reference Antibody is produced in CHO cells and consists of a huIgG1 heavy chain and a hukappa light chain. This compound has a predicted molecular weight (MW) of 146.06 kDa.</p>Color and Shape:LiquidMolecular weight:150 kDaIFN-α Receptor Recognition Peptide 1
CAS:<p>IFN-α Receptor Recognition Peptide 1, associated with receptor interactions, is a peptide of IFN-α.</p>Formula:C35H59N13O12SPurity:98%Color and Shape:SolidMolecular weight:885.99MTvkPABC-P5 TFA
<p>MTvkPABC-P5d TFA, a TLR7 agonist, functions as an immune stimulant. It is applicable in the synthesis of immune-stimulating antibody conjugates (ISAC).</p>Color and Shape:Odour SolidPSMA-DA1
CAS:PSMA–DA1 may be a useful PSMA-targeting radiotheranostic agent.Formula:C50H76IN9O20Color and Shape:SolidMolecular weight:1250.1058-Nitroguanine
CAS:<p>8-Nitroguanine is a product of DNA nitration damage caused by reactive nitrogen species and may be a potential biomarker for the progression of malignant</p>Formula:C5H4N6O3Color and Shape:SolidMolecular weight:196.12Bectumomab
CAS:<p>Bectumomab (IMMU-LL2) is a humanized IgG2a mAb targeting CD22, used in imaging and staging non-Hodgkin's lymphoma.</p>Color and Shape:LiquidUbletamig
CAS:<p>Ubletamig is a humanized IgG4κ monoclonal antibody that targets MUC16.</p>Color and Shape:LiquidRucosopasem manganese
CAS:<p>Rucosopasem manganese (GC4711), a selective SOD mimetic, converts superoxide to peroxide for cancer research.</p>Formula:C27H45MnN5O4Color and Shape:SolidMolecular weight:558.626TBK1/IKKε-IN-6
CAS:TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.Formula:C31H36F2N8O4Color and Shape:SolidMolecular weight:622.678Efmarodocokin alfa
CAS:Efmarodocokin alfa, IL-22/IgG4 fusion protein, activates IL-22 pathways, researched for severe COVID-19 pneumonia.Color and Shape:LiquidHydroxychloroquine Impurity E
CAS:Hydroxychloroquine Impurity E, a byproduct, can block TLR7/9 and inhibit SARS-CoV-2 in vitro.Formula:C14H17ClN2OColor and Shape:SolidMolecular weight:264.75NHEJ inhibitor-1
NHEJ inhibitor-1 (C2) is a Pt(II) complex that targets DSB repair to combat Cisplatin-resistant NSCLC by hindering Ku70/Rad51 and inducing ROS.Formula:C30H35N7O8PtSColor and Shape:SolidMolecular weight:848.79BTH1704
<p>BTH1704 is a human monoclonal antibody targeting MUC1. It facilitates the killing of iC3b-opsonized tumor cells by leukocytes triggered by PGG. BTH1704 is applicable in studies on pancreatic cancer and breast cancer.</p>Color and Shape:Odour LiquidNLRP3-IN-46
<p>NLRP3-IN-46 (Compound 3k) activates the cholinergic anti-inflammatory pathway involved in neuro-immune modulation, thereby inhibiting the activation of the NLRP3 inflammasome. Furthermore, NLRP3-IN-46 suppresses the production of IL-1β in THP-1 cells induced by Uric acid sodium, making it relevant for research in gouty arthritis.</p>Color and Shape:Odour SolidCD73-IN-16
<p>CD73-IN-16 (compound 18) acts as an inhibitor of hCD73, exhibiting an IC50 value of 0.28 μM.</p>Color and Shape:Odour SolidSU1261
<p>SU1261, an IKK inhibitor, exhibits Ki values of 10 nM for IKKα and 680 nM for IKKβ. It effectively inhibits non-canonical NF-κB signaling in U2OS osteosarcoma cells.</p>Color and Shape:Odour SolidVemircopan
CAS:Vemircopan is a complement factor D inhibitor.Formula:C29H28BrN7O3Color and Shape:SolidMolecular weight:602.493COX-2-IN-48
<p>COX-2-IN-48 (5-25) serves as an inhibitor of COX-2, exhibiting an IC50 of 51.7 nM against human COX-2. It displays anti-inflammatory and analgesic effects in various rodent models through inhibition of the NF-κB pathway. COX-2-IN-48 (5-25) inhibits the degradation of IκB, phosphorylation and nuclear translocation of NF-κB p65, and the expression of COX-2 and iNOS.</p>Color and Shape:Odour SolidEnglumafusp alfa
Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion protein combining a CD19-specific antibody domain with trimerized extracellular domains of human 4-1BBL,Color and Shape:Odour LiquidIL-1β-IN-1
CAS:<p>IL-1β-IN-1, a cannabidiol derivative, acts as a potent inhibitor of IL-1β, exhibiting significant anti-inflammatory and pain relief properties [1].</p>Formula:C22H34O2Color and Shape:SolidMolecular weight:330.5
