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NOS

NOS

Nitric oxide synthase (NOS) is an enzyme responsible for the production of nitric oxide (NO), a signaling molecule involved in vasodilation, neurotransmission, and immune responses. There are three isoforms of NOS: neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), each playing distinct roles in physiological and pathological processes. Dysregulation of NOS activity is implicated in cardiovascular diseases, neurodegeneration, and inflammatory conditions. At CymitQuimica, we offer a selection of NOS modulators to support your research in vascular biology, neurobiology, and immunology.

Found 63 products of "NOS"

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  • Chondroitin sulfate

    CAS:
    <p>Chondroitin sulfate (Chonsurid) is extracted from shark bone;Store the product in sealed, cool and dry condition</p>
    Formula:(C14H21NO14S)n
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:30,000-50,000
  • 2-Thiouracil

    CAS:
    <p>2-Thiouracil (Deracil) is a thiolated uracil derivative that is a known anti-hyperthyroid agent.</p>
    Formula:C4H4N2OS
    Purity:99.89%
    Color and Shape:Minute Crystals Prisms Or White Or Pale Cream-Colored Powder White To Pale Yellow Crystalline Powder
    Molecular weight:128.15
  • Carboxyebselen

    CAS:
    <p>Carboxyebselen (HOOC-Ebs) is an endothelial nitric oxide synthase (eNOS) inhibitor that is potent and selective.</p>
    Formula:C14H9NO3Se
    Purity:98%
    Color and Shape:Solid
    Molecular weight:318.19
  • Mifepristone

    CAS:
    <p>Mifepristone (C-1073) is a progesterone-receptor (IC50=0.2 nM) and glucocorticoid-receptor antagonist (IC50=2.6 nM). High-Quality, Low-Cost!</p>
    Formula:C29H35NO2
    Purity:98.9% - ≥95%
    Color and Shape:Pale Yellow Solid
    Molecular weight:429.59
  • Aminoguanidine hydrochloride

    CAS:
    <p>Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy.</p>
    Formula:CH6N4·HCl
    Purity:99.80%
    Color and Shape:White To Off-White Solid
    Molecular weight:110.55
  • L-Arginine hydrochloride

    CAS:
    <p>L-Arginine hydrochloride is a nitrogen donor for synthesis of nitric oxide.</p>
    Formula:C6H15ClN4O2
    Purity:99.51%
    Color and Shape:White Solid Crystalline
    Molecular weight:210.66
  • S-Nitroso-N-acetyl-DL-penicillamine

    CAS:
    <p>S-Nitroso-N-acetyl-DL-penicillamine (SNAP) acts as a stable inhibitor of platelet aggregation, is a nitric oxide donor and .</p>
    Formula:C7H12N2O4S
    Purity:97.42% - >99.99%
    Color and Shape:Green Crystalline Solid
    Molecular weight:220.25
  • Bendazol

    CAS:
    <p>Bendazol (Dibazol) is always used as the drug for hypertension and cerebral Angiospasm.</p>
    Formula:C14H12N2
    Purity:98.7% - 99.87%
    Color and Shape:White Or Almost White Crystalline Powder
    Molecular weight:208.26
  • Isosorbide dinitrate

    CAS:
    <p>Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris.</p>
    Formula:C6H8N2O8
    Purity:99.87%
    Color and Shape:Hard Colorless Crystals Solid
    Molecular weight:236.14
  • NOS-IN-1 

    CAS:
    <p>NOS-IN-1: a potent oral NO synthase blocker, with IC50 of 0.1μM (iNOS), 0.2μM (nNOS), 1.1μM (eNOS).</p>
    Formula:C8H16N2O2
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:172.22
  • Epibetulinic acid

    CAS:
    <p>Epibetulinic acid reduces inflammation, suppressing NO and prostaglandin E2 in endotoxin-stimulated mouse macrophages.</p>
    Formula:C30H48O3
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:456.7
  • 3-O-Acetyl-16α-hydroxydehydrotrametenolic acid

    CAS:
    <p>3-O-Acetyl-16α-hydroxydehydrotrametenolic acid (3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid) shows anti-inflammatory activity, it can inhibit NO</p>
    Formula:C32H48O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:512.72
  • 2-Iminobiotin

    CAS:
    <p>2-Iminobiotin inhibits iNOS/nNOS; Ki: 21.8 μM (mouse iNOS), 37.5 μM (rat nNOS).</p>
    Formula:C10H17N3O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:243.33
  • Physalin L

    CAS:
    <p>Physalin L is a natural product,it shows a distinct fluorescence spot under UV 365 nm with good separation.</p>
    Formula:C28H32O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:528.55
  • Banoxantrone dihydrochloride

    CAS:
    <p>Banoxantrone dihydrochloride (AQ4N dihydrochloride) is a novel hypoxic cytotoxin that selectively kills hypoxic cells through an iNOS-dependent mechanism.</p>
    Formula:C22H30Cl2N4O6
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:517.4
  • Asperuloside

    CAS:
    <p>Asperuloside (Asperulosid) has anti-inflammatory activity.</p>
    Formula:C18H22O11
    Purity:98.03% - 99.42%
    Color and Shape:Solid
    Molecular weight:414.36
  • Asymmetric dimethylarginine

    CAS:
    <p>Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)</p>
    Formula:C8H18N4O2
    Purity:98% - 99.62%
    Color and Shape:Solid
    Molecular weight:202.25
  • 7-Nitroindazole

    CAS:
    <p>7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS.</p>
    Formula:C7H5N3O2
    Purity:96.15% - 99.05%
    Color and Shape:Orange-Yellow Solid
    Molecular weight:163.13
  • Tryptanthrin

    CAS:
    <p>Tryptanthrin is a natural DNA gyrase inhibitor.</p>
    Formula:C15H8N2O2
    Purity:99.64% - 99.94%
    Color and Shape:Solid
    Molecular weight:248.24
  • Ethyl 3,4-dihydroxybenzoate

    CAS:
    <p>Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.</p>
    Formula:C9H10O4
    Purity:99.88%
    Color and Shape:White Crystal Or Powder
    Molecular weight:182.17
  • α-Humulene

    CAS:
    <p>α-Humulene (Alpha-caryophyllene) is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory</p>
    Formula:C15H24
    Purity:97.18% - 97.18%
    Color and Shape:Liquid
    Molecular weight:204.35
  • Diphenyleneiodonium chloride

    CAS:
    <p>Diphenyleneiodonium chloride (DPI) inhibits iNOS &amp; eNOS (IC50: 50 nM &amp; 0.3 μM) and has wide-ranging bactericidal properties.</p>
    Formula:C12H8ClI
    Purity:99.71% - 99.86%
    Color and Shape:Solid
    Molecular weight:314.55
  • Piceatannol 3'-O-glucoside

    CAS:
    <p>Piceatannol 3'-O-glucoside (Piceatannol 3-glycoside) increases pulmonary blood oxygen tension and decreases pulmonary interstitial edema, so it can protect lung</p>
    Formula:C20H22O9
    Purity:99.47% - 99.97%
    Color and Shape:Solid
    Molecular weight:406.38
  • S-Methylisothiourea sulfate

    CAS:
    <p>S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) is a potent and selective inhibitor of iNOS and exerts beneficial effects in rodent models of septic</p>
    Formula:C2H6N2SH2O4S
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:139.18
  • Midostaurin

    CAS:
    <p>PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.</p>
    Formula:C35H30N4O4
    Purity:97.61% - >99.99%
    Color and Shape:Solid
    Molecular weight:570.64
  • Avanafil

    CAS:
    <p>Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction.</p>
    Formula:C23H26ClN7O3
    Purity:99.03% - >99.99%
    Color and Shape:White Solid
    Molecular weight:483.95
  • Ginsenoside Rb3

    CAS:
    <p>Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.</p>
    Formula:C53H90O22
    Purity:98% - 99.98%
    Color and Shape:Solid
    Molecular weight:1079.27
  • L-Canavanine sulfate

    CAS:
    <p>L-Canavanine sulfate is a selective inducible NO synthase inhibitor.</p>
    Formula:C5H14N4O7S
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:274.25
  • 6-Biopterin

    CAS:
    <p>6-Biopterin (L-Biopterin) is a natural product,is a NO synthase cofactor.</p>
    Formula:C9H11N5O3
    Purity:99.11%
    Color and Shape:Solid
    Molecular weight:237.22
  • Irisflorentin

    CAS:
    <p>Irisflorentin prevents cell death, boosts proteasomes via rpn-3, reduces egl-1, and lowers iNOS/NO in LPS-stimulated macrophages.</p>
    Formula:C20H18O8
    Purity:98.6% - 99.81%
    Color and Shape:Solid
    Molecular weight:386.35
  • Methylene Blue

    CAS:
    <p>Methylene Blue (Tetramethylthionine chloride) (IC50 of 1.9 μM) inhibits tau filament formation. And methylene Blue inhibits soluble guanylyl cyclase.</p>
    Formula:C16H18ClN3S
    Purity:95.80%
    Color and Shape:Dark Green Crystals Or Powder From Chloroform-Ethyl Ether Green Fine Crystalline Powder
    Molecular weight:319.85
  • Pectolinarin

    CAS:
    <p>Pectolinarin is a Cirsium isolate with anti-inflammatory activity.</p>
    Formula:C29H34O15
    Purity:98% - 99.79%
    Color and Shape:Solid
    Molecular weight:622.57
  • PRE-084 hydrochloride

    CAS:
    <p>PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).</p>
    Formula:C19H28ClNO3
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:353.88
  • Agmatine sulfate

    CAS:
    <p>Agmatine sulfate (Agmatine sulfate salt) is a bioactive metabolite of the arginine amino acid.</p>
    Formula:C5H16N4O4S
    Purity:99.56% - 99.86%
    Color and Shape:White To Off-White Powder
    Molecular weight:228.27
  • Regaloside B

    CAS:
    <p>Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression of iNOS (inducible nitric</p>
    Formula:C20H26O11
    Purity:99.4% - 99.57%
    Color and Shape:Solid
    Molecular weight:442.41
  • anemarsaponin B

    CAS:
    <p>Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity</p>
    Formula:C45H74O18
    Purity:99.06% - 99.81%
    Color and Shape:Solid
    Molecular weight:903.06
  • Dehydroevodiamine

    CAS:
    <p>Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant</p>
    Formula:C19H15N3O
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:301.34
  • 7-Ethoxyresorufin

    CAS:
    <p>7-Ethoxyresorufin (Resorufin ethyl ether) (7-ER) is a fluorometric substrate for and competitive inhibitor of cytochrome P450, especially CYP1A1.</p>
    Formula:C14H11NO3
    Purity:99.09% - 99.62%
    Color and Shape:Red Solid
    Molecular weight:241.24
  • L-Arginine

    CAS:
    <p>L-Arginine (L-Arg) is a substrate of endothelial nitric oxide synthase (eNOS). High-Quality, Low-Cost!</p>
    Formula:C6H14N4O2
    Purity:99.7% - 99.98%
    Color and Shape:Solid Crystalline
    Molecular weight:174.2
  • Prim-O-glucosylcimifugin

    CAS:
    <p>Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC stimulated by TNF-alpha, increase the proportion of G0/G1 phase.</p>
    Formula:C22H28O11
    Purity:98.57% - 99.92%
    Color and Shape:Solid
    Molecular weight:468.45
  • Methylene Blue trihydrate

    CAS:
    <p>Dark green, bronze-lustered Methylene Blue trihydrate is a deep blue dye in water/alcohol, used in staining, cyanide treatment, and methemoglobin reduction.</p>
    Formula:C16H24ClN3O3S
    Purity:95.42% - 99.6%
    Color and Shape:Dark Green Solid
    Molecular weight:373.9
  • 1400W dihydrochloride

    CAS:
    <p>1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).</p>
    Formula:C10H17Cl2N3
    Purity:98% - 99.94%
    Color and Shape:Solid
    Molecular weight:250.17
  • N'-Nitro-D-arginine

    CAS:
    <p>N'-Nitro-D-arginine (N'-Nitro-D-arginine) is a Building Block.</p>
    Formula:C6H13N5O4
    Purity:99.81%
    Color and Shape:White To Off White Powder
    Molecular weight:219.2
  • Dimaprit dihydrochloride

    CAS:
    <p>Dimaprit dihydrochloride: selective H2 agonist, inhibits nNOS (IC50: 49 μM), boosts gastric acid.</p>
    Formula:C6H15N3S·2HCl
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:234.19
  • ETHYL CAFFEATE

    CAS:
    <p>Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.</p>
    Formula:C11H12O4
    Purity:97.79%
    Color and Shape:Solid
    Molecular weight:208.21
  • Isoquercetin

    CAS:
    <p>1.</p>
    Formula:C21H20O12
    Purity:98.08% - 99.76%
    Color and Shape:Solid
    Molecular weight:464.38
  • Harpagoside

    CAS:
    <p>Harpagoside: anti-inflammatory; 3 mM inhibits seed germination; reduces COX-2, iNOS mRNA, and protein in HepG2.</p>
    Formula:C24H30O11
    Purity:99.71% - ≥95%
    Color and Shape:White To Off-White Powder
    Molecular weight:494.49
  • TRIM

    CAS:
    <p>TRIM (1-(2-Trifluoromethylphenyl)imidazole) is an inhibitor of nNOS.</p>
    Formula:C10H7F3N2
    Purity:98.98%
    Color and Shape:White Solid
    Molecular weight:212.17
  • 2-Iminobiotin hydrobromide

    CAS:
    <p>2-Iminobiotin hydrobromide (Guanidinobiotin) is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS</p>
    Formula:C10H18BrN3O2S
    Purity:98.13%
    Color and Shape:Solid
    Molecular weight:324.24
  • Ginsenoside C-K

    CAS:
    <p>Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.</p>
    Formula:C36H62O8
    Purity:99.65% - 99.97%
    Color and Shape:Solid
    Molecular weight:622.87
  • Crocin II

    CAS:
    <p>Crocin II combats gastric and liver injuries, reduces inflammation, apoptosis, oxidative stress, and may lower lipid levels and have antidepressant effects.</p>
    Formula:C38H54O19
    Purity:98% - 99.00%
    Color and Shape:Solid
    Molecular weight:814.82
  • 2,4-Diamino-6-hydroxypyrimidine

    CAS:
    <p>2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis</p>
    Formula:C4H6N4O
    Purity:99.82%
    Color and Shape:White Solid Crystals
    Molecular weight:126.12
  • L-NAME hydrochloride

    CAS:
    <p>L-NAME hydrochloride (L-NAME HCl), a cell-permeable NO synthase inhibitor, displays Ki values of 4.4 μM, 15 nM, and 39 nM, for iNOS (mouse) , nNOS (bovine) ,</p>
    Formula:C7H15N5O4·HCl
    Purity:98.71% - 99.93%
    Color and Shape:White To Off-White Powder
    Molecular weight:269.69
  • Madecassic acid

    CAS:
    <p>Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.</p>
    Formula:C30H48O6
    Purity:98.80% - 99.69%
    Color and Shape:Solid
    Molecular weight:504.7
  • Cistanoside A

    CAS:
    <p>Cistanoside A protects mice from CCl4-induced liver damage by enhancing radical clearance, reducing lipid peroxidation, and boosting mitochondrial function.</p>
    Formula:C36H48O20
    Purity:98.24% - 99.86%
    Color and Shape:Solid
    Molecular weight:800.75
  • EIT hydrobromide

    CAS:
    <p>EIT hydrobromide (S-Ethylisothiourea hydrobromide) is an iNOS inhibitor.</p>
    Formula:C3H9BrN2S
    Purity:99.81%
    Color and Shape:White Crystalline Solid
    Molecular weight:185.09
  • 3,4-DAA

    CAS:
    <p>3,4-DAA has anti-inflammatory activity and inhibits EOC20 cell-induced nitric oxide synthase (iNOS) induced by IFN-γ and lipopolysaccharide.</p>
    Formula:C18H17NO6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:343.33
  • L-NMMA acetate

    CAS:
    <p>L-NMMA acetate inhibits all NOS types (nNOS, eNOS, iNOS); Ki: 0.18, 0.4, 6 µM respectively.</p>
    Formula:C9H20N4O4
    Purity:99.72% - 99.8%
    Color and Shape:White To Off-White Solid
    Molecular weight:248.28
  • AVE-9488

    CAS:
    <p>AVE-9488 is a novel endothelial NO synthase (eNOS) enhancer that upregulates eNOS expression, induces NO production, and may ameliorate portal hypertension.</p>
    Formula:C16H14FNO
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:255.29
  • 3-Bromo-7-nitroindazole

    CAS:
    <p>3-Bromo-7-nitroindazole specifically inhibits nNOS, impacting NO synthesis in brain/body.</p>
    Formula:C7H4BrN3O2
    Purity:98.2%
    Color and Shape:Yellowish Solid
    Molecular weight:242.03
  • Kuwanon A

    CAS:
    <p>Kuwanon A inhibits nitric oxide production (IC50: 10.5 μM). Kuwanon A is a flavone derivative isolated from Morus alba L.</p>
    Formula:C25H24O6
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:420.45
  • Celiprolol hydrochloride

    CAS:
    <p>Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity.</p>
    Formula:C20H33N3O4·HCl
    Color and Shape:White Crystalline Solid
    Molecular weight:415.96
  • Dimethoxycurcumin

    CAS:
    <p>Dimethoxycurcumin is a stable curcumin analog causing epigenetic shifts in leukemia cells, affecting gene expression.</p>
    Formula:C23H24O6
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:396.43