JAK/STAT signaling
JAK/STAT signaling inhibitors are compounds that disrupt the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, which is involved in cytokine signaling, cell growth, and immune response. These inhibitors are important tools in studying the regulation of this pathway and its role in various diseases, including cancers, immune disorders, and inflammatory conditions. JAK/STAT inhibitors are also being developed as targeted therapies for these diseases. At CymitQuimica, we provide a wide selection of high-quality JAK/STAT signaling inhibitors to support your research in molecular biology, oncology, and immunology.
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Products of "JAK/STAT signaling"
JAK-IN-10
CAS:916741-98-5
JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye …
Formula:
C20H18FN5O3S
Purity:
98.88%
Color and Shape:
Solid
Molecular weight:
427.45
Ref: TM-T13571
| 1mg | 85.00 € | ||
| 5mg | 174.00 € | ||
| 10mg | 255.00 € | ||
| 25mg | 420.00 € | ||
| 50mg | 592.00 € | ||
| 100mg | 799.00 € | ||
| 500mg | 1,591.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
JAK-IN-28
CAS:2445500-22-9
JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of …
Formula:
C20H18ClN7O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
407.86
Ref: TM-T79116
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
K00135
CAS:869650-21-5
K00135 (IMIDAZOPYRIDAZIN 1) is a selective inhibitor of Pim kinases and can be used in …
Formula:
C18H18N4O
Purity:
97.88%
Color and Shape:
Solid
Molecular weight:
306.36
Ref: TM-T27704
| 1mg | 111.00 € | ||
| 2mg | 167.00 € | ||
| 5mg | 247.00 € | ||
| 10mg | 362.00 € | ||
| 25mg | 542.00 € | ||
| 50mg | 762.00 € | ||
| 100mg | 1,025.00 € | ||
| 200mg | 1,391.00 € | ||
| 1mL*10mM (DMSO) | 240.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
JAK3/BTK-IN-2
CAS:2674036-93-0
JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.
Formula:
C25H32N8O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
476.57
Ref: TM-T9813
| 25mg | 1,234.00 € | ||
| 50mg | 1,605.00 € | ||
| 100mg | 2,419.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
JAK3i
CAS:1918238-72-8
JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T …
Formula:
C18H15FN4O3
Purity:
99.72% - 99.81%
Color and Shape:
Solid
Molecular weight:
354.34
Ref: TM-T27650
| 1mg | 326.00 € | ||
| 5mg | 769.00 € | ||
| 10mg | 1,050.00 € | ||
| 25mg | 1,476.00 € | ||
| 50mg | 1,850.00 € | ||
| 1mL*10mM (DMSO) | 658.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
ABBV-712
CAS:2368945-27-9
ABBV-712 is a selective Tyrosine Kinase 2 (TYK2) inhibitor, demonstrating an IC50 value of 0.195 …
Formula:
C24H28N4O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
452.5
Ref: TM-T83218
| 5mg | 1,354.00 € | ||
| 10mg | 1,824.00 € | ||
| 25mg | 2,435.00 € | ||
| 50mg | 3,070.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
STAT3-IN-18
CAS:2668267-41-0
STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the …
Formula:
C18H24Cl2N2O6Pt
Purity:
98%
Color and Shape:
Solid
Molecular weight:
630.38
Ref: TM-T79609
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 2 Jan 2025
JAK2-IN-4
CAS:1438284-00-4
JAK2-IN-4 is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM …
Formula:
C23H27N5O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
469.56
Ref: TM-T11708
| 25mg | 1,827.00 € | ||
| 50mg | 2,413.00 € | ||
| 100mg | 3,180.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
JAK-IN-34
CAS:2068766-90-3
JAK-IN-34 (compound 11n) is a potent inhibitor of Janus kinases (JAKs), demonstrating IC50 values of …
Formula:
C27H26N6O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
450.53
Ref: TM-T82017
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 2 Jan 2025
FD1024
CAS:1422456-47-0
FD1024 is a potent PIM inhibitor, displaying inhibitory concentrations (IC50s) of 1.96 nM, 38.9 nM, …
Formula:
C21H20F2N4O2S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
430.47
Ref: TM-T79456
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 2 Jan 2025
Lepzacitinib
CAS:2321488-47-3
Lepzacitinib, a Janus kinase inhibitor, specifically targets JAK 1/3.
Formula:
C18H21N5O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
355.39
Ref: TM-T78207
| 2mg | 91.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
TCS 21311
CAS:1260181-14-3
TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective …
Formula:
C27H25F3N4O4
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
526.51
Ref: TM-T17019
| 1mg | 96.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
JAK1-IN-10
CAS:2416858-88-1
JAK1-IN-10 (compound 9), a cyano-substituted cyclic hydrazine derivative, functions as a potent and selective inhibitor …
Formula:
C15H17N7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
295.34
Ref: TM-T79078
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 2 Jan 2025
JAK-IN-26
CAS:2417134-93-9
JAK-IN-26 (compound 2) is an orally active inhibitor of the Janus kinase (JAK) enzyme with …
Formula:
C22H24N6O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
420.46
Ref: TM-T78189
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 2 Jan 2025
Pim-1 kinase inhibitor 5
CAS:2928606-67-9
Pim-1 kinase inhibitor 5 (Compound 4c), with an IC50 of 0.61 μM, exhibits cytotoxicity against …
Formula:
C22H13Cl2N3O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
406.26
Ref: TM-T78980
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 2 Jan 2025
GNE-955
CAS:1527523-39-2
GNE-955 is a potent and orally active inhibitor of pan Pim kinase (Kis: 0.018, 0.11, …
Formula:
C22H24N8O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
416.48
Ref: TM-T15406
| 25mg | 1,822.00 € | ||
| 50mg | 2,413.00 € | ||
| 100mg | 3,180.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
PIM1-IN-1
CAS:1417630-95-5
PIM1-IN-1 inhibits PIM1/3 with IC50s: PIM1 (7 nM), PIM2 (5530 nM), PIM3 (70 nM); it …
Formula:
C25H30N8O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
474.56
Ref: TM-T12474
| 25mg | 1,058.00 € | ||
| 50mg | 1,385.00 € | ||
| 100mg | 2,258.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Ginsenoside Rk1
CAS:494753-69-4
Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.
Formula:
C42H70O12
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
767
Ref: TM-T4S1499
| 5mg | 91.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
JAK-IN-31
CAS:2597016-88-9
JAK-IN-31 (Example 75), a JAK inhibitor, demonstrates IC50 values of ≤0.01 µM for JAK1, ≤0.01 …
Formula:
C21H19N7O2S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
465.55
Ref: TM-T79882
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 2 Jan 2025
JAK-IN-27
CAS:2673176-36-6
JAK-IN-27, also known as compound 1, is an orally active, potent inhibitor of the JAKS …
Formula:
C20H21F2N7O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
413.42
Ref: TM-T79110
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 2 Jan 2025
