JAK/STAT signaling
JAK/STAT signaling inhibitors are compounds that disrupt the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, which is involved in cytokine signaling, cell growth, and immune response. These inhibitors are important tools in studying the regulation of this pathway and its role in various diseases, including cancers, immune disorders, and inflammatory conditions. JAK/STAT inhibitors are also being developed as targeted therapies for these diseases. At CymitQuimica, we provide a wide selection of high-quality JAK/STAT signaling inhibitors to support your research in molecular biology, oncology, and immunology.
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Products of "JAK/STAT signaling"
SMI-16a
CAS:587852-28-6
SMI-16a (PIM1/2 Kinase Inhibitor VI) , a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive …
Formula:
C13H13NO3S
Purity:
99.99%
Color and Shape:
Solid
Molecular weight:
263.31
Ref: TM-T3989
| 1mg | 35.00 € | ||
| 2mg | 48.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 160.00 € | ||
| 50mg | 235.00 € | ||
| 100mg | 354.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
HJ-PI01
CAS:6192-43-4
HJ-PI01 (HJ-PI01) is a Pim-2 inhibitor. HJ-PI01 (HJ-PI01) induces apoptosis and autophagic cell death in …
Formula:
C14H11NO2
Purity:
99.55%
Color and Shape:
Solid
Molecular weight:
225.24
Ref: TM-T9583
| 1mg | 35.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 259.00 € | ||
| 50mg | 383.00 € | ||
| 100mg | 545.00 € | ||
| 200mg | 740.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
JAK-IN-5 hydrochloride
CAS:2751323-21-2
JAK-IN-5 hydrochloride is a JAK inhibitor [1].
Formula:
C27H32ClFN6O
Color and Shape:
Liquid
Molecular weight:
511.03
Ref: TM-T11710L
| 25mg | 1,539.00 € | ||
| 50mg | 2,005.00 € | ||
| 100mg | 2,992.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
WHI-P97 HCl
WHI-P97 HCl is a potent and selective JAK-3 inhibitor.
Formula:
C16H14Br2ClN3O3
Purity:
99.49%
Color and Shape:
Solid
Molecular weight:
491.56
Ref: TM-T4657L
| 1mg | 42.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 202.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 395.00 € | ||
| 200mg | 562.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Abrocitinib
CAS:1622902-68-4
Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for …
Formula:
C14H21N5O2S
Purity:
99.09% - 99.91%
Color and Shape:
Solid
Molecular weight:
323.41
Ref: TM-TQ0037
| 1mg | 85.00 € | ||
| 2mg | 107.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 284.00 € | ||
| 25mg | 467.00 € | ||
| 50mg | 692.00 € | ||
| 100mg | 938.00 € | ||
| 1mL*10mM (DMSO) | 188.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
AZD1208
CAS:1204144-28-4
AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency …
Formula:
C21H21N3O2S
Purity:
97.24% - 98.87%
Color and Shape:
Solid
Molecular weight:
379.48
Ref: TM-T2300
| 2mg | 38.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 118.00 € | ||
| 50mg | 213.00 € | ||
| 100mg | 378.00 € | ||
| 200mg | 495.00 € | ||
| 500mg | 792.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Atractylenolide I
CAS:73069-13-3
Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to …
Formula:
C15H18O2
Purity:
97.55% - 99.83%
Color and Shape:
Solid
Molecular weight:
230.3
Ref: TM-T5S0167
| 1mg | 43.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 131.00 € | ||
| 25mg | 240.00 € | ||
| 50mg | 424.00 € | ||
| 100mg | 592.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
XL019
CAS:945755-56-6
XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold …
Formula:
C25H28N6O2
Purity:
99.19%
Color and Shape:
Solid
Molecular weight:
444.53
Ref: TM-T3072
| 5mg | 74.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 522.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
NVP-BSK805
CAS:1092499-93-8
NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.
Formula:
C27H28F2N6O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
490.55
Ref: TM-T5049
| 1mg | 63.00 € | ||
| 5mg | 131.00 € | ||
| 10mg | 210.00 € | ||
| 25mg | 410.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
SD-1029
CAS:118372-34-2
SD-1029 is a JAK2 inhibitor and a novel Stat3 activation inhibitor that inhibits Stat3 phosphorylation …
Formula:
C25H32Br2Cl2N2O3
Color and Shape:
Solid
Molecular weight:
639.25
Ref: TM-T24774
| 1mg | 93.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
K00135
CAS:869650-21-5
K00135 (IMIDAZOPYRIDAZIN 1) is a selective inhibitor of Pim kinases and can be used in …
Formula:
C18H18N4O
Purity:
97.88%
Color and Shape:
Solid
Molecular weight:
306.36
Ref: TM-T27704
| 1mg | 185.00 € | ||
| 2mg | 279.00 € | ||
| 5mg | 426.00 € | ||
| 10mg | 627.00 € | ||
| 25mg | 938.00 € | ||
| 50mg | 1,320.00 € | ||
| 100mg | 1,786.00 € | ||
| 500mg | 3,591.00 € | ||
| 1mL*10mM (DMSO) | 415.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
JAK-IN-11
CAS:916742-11-5
JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the …
Formula:
C23H22FN5O4S
Purity:
99.57%
Color and Shape:
Solid
Molecular weight:
483.52
Ref: TM-T12549
| 1mg | 284.00 € | ||
| 5mg | 568.00 € | ||
| 10mg | 924.00 € | ||
| 25mg | 1,681.00 € | ||
| 50mg | 2,262.00 € | ||
| 1mL*10mM (DMSO) | 645.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
JBJ-04-125-02
CAS:2060610-53-7
JBJ-04-125-02: Oral EGFR inhibitor, targets EGFRL858R/T790M with 0.26 nM IC50, halts cancer growth, anti-tumor.
Formula:
C29H26FN5O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
543.61
Ref: TM-T11714
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
CX-6258
CAS:1202916-90-2
CX-6258 is an orally valid Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor. It has good …
Formula:
C26H24ClN3O3
Purity:
95.88%
Color and Shape:
Solid
Molecular weight:
461.94
Ref: TM-T1834
| 1mg | 37.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 106.00 € | ||
| 25mg | 208.00 € | ||
| 50mg | 311.00 € | ||
| 100mg | 472.00 € | ||
| 200mg | 658.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
JAK-IN-10
CAS:916741-98-5
JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye …
Formula:
C20H18FN5O3S
Purity:
98.88%
Color and Shape:
Solid
Molecular weight:
427.45
Ref: TM-T13571
| 1mg | 87.00 € | ||
| 5mg | 177.00 € | ||
| 10mg | 260.00 € | ||
| 25mg | 429.00 € | ||
| 50mg | 605.00 € | ||
| 100mg | 815.00 € | ||
| 500mg | 1,624.00 € | ||
| 1mL*10mM (DMSO) | 188.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
JAK3-IN-1
CAS:1805787-93-2
JAK3-IN-1 is an orally active, selective and potent JAK3 inhibitor for the study of immune …
Formula:
C26H30ClN7O2
Color and Shape:
Solid
Molecular weight:
508.02
Ref: TM-T15607
| 5mg | 216.00 € | ||
| 25mg | 727.00 € | ||
| 50mg | 947.00 € | ||
| 100mg | 1,320.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
JAK3/BTK-IN-1
CAS:2674036-91-8
JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 …
Formula:
C25H28N8O
Purity:
97.89%
Color and Shape:
Liquid
Molecular weight:
456.54
Ref: TM-T9814
| 1mg | 235.00 € | ||
| 5mg | 587.00 € | ||
| 10mg | 835.00 € | ||
| 25mg | 1,264.00 € | ||
| 50mg | 1,634.00 € | ||
| 100mg | 2,460.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
JAK-STAT-IN-1
CAS:1236666-76-4
JAK-STAT-IN-1 is a specific JAK-STAT inhibitor indicated for the study of autoimmune diseases.
Formula:
C21H21N5O2
Purity:
99.21%
Color and Shape:
Liquid
Molecular weight:
375.42
Ref: TM-T78607
| 1mg | 185.00 € | ||
| 5mg | 459.00 € | ||
| 10mg | 657.00 € | ||
| 25mg | 1,026.00 € | ||
| 50mg | 1,415.00 € | ||
| 100mg | 1,872.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
JAK-IN-30
CAS:2891469-99-9
JAK-IN-30 (compound 31) is a water-soluble inhibitor of Janus kinases (JAKs), demonstrating inhibitory potency with …
Formula:
C19H26N8S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
398.53
Ref: TM-T79235
| 1mg | 123.00 € | ||
| 5mg | 465.00 € | ||
| 10mg | 832.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
JAK2-IN-9
CAS:2568842-26-0
Compound A8, known as JAK2-IN-9, is a selective JAK2 inhibitor with an IC50 of 5 …
Formula:
C20H24N6O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
412.51
Ref: TM-T79581
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
