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JAK/STAT signaling

JAK/STAT signaling inhibitors are compounds that disrupt the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, which is involved in cytokine signaling, cell growth, and immune response. These inhibitors are important tools in studying the regulation of this pathway and its role in various diseases, including cancers, immune disorders, and inflammatory conditions. JAK/STAT inhibitors are also being developed as targeted therapies for these diseases. At CymitQuimica, we provide a wide selection of high-quality JAK/STAT signaling inhibitors to support your research in molecular biology, oncology, and immunology.

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Subcategories of "JAK/STAT signaling"

JAK

Pim

STAT

Products of "JAK/STAT signaling"

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BrandProduct dataPurityPrice rangeEstimated delivery
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Ruxolitinib
REF: TM-T1829CAS: 941678-49-5 		100% - 99.99%58.00 €~600.00 €Tue 11 Mar 25
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Solcitinib
REF: TM-T3620CAS: 1206163-45-2 		98.25% - 99.82%37.00 €~301.00 €Tue 11 Mar 25
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Fosifidancitinib
REF: TM-T38624CAS: 1237168-58-9 		99.55%87.00 €~1,159.00 €Tue 11 Mar 25
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Oclacitinib maleate
REF: TM-T6914CAS: 1640292-55-2 		99.17%39.00 €~457.00 €Tue 11 Mar 25
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(Z)-SMI-4a
REF: TM-T3058CAS: 438190-29-5 		97.66% - 99.44%51.00 €~489.00 €Tue 11 Mar 25
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Oclacitinib
REF: TM-T2012CAS: 1208319-26-9 		98% - 98.12%47.00 €~274.00 €Tue 11 Mar 25
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AZD-1480
REF: TM-T3069CAS: 935666-88-9 		97.5% - 98.55%To inquireTue 11 Mar 25
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JAK-IN-5 hydrochloride
REF: TM-T11710LCAS: 2751323-21-2 		- - -144.00 €~2,992.00 €Tue 11 Mar 25
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NVP-BSK805
REF: TM-T5049CAS: 1092499-93-8 		98%63.00 €~410.00 €Wed 19 Mar 25
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JAK-IN-11
REF: TM-T12549CAS: 916742-11-5 		99.57%284.00 €~4,994.00 €Tue 22 Apr 25
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JAK1-IN-4
REF: TM-T15606CAS: 2091134-35-7 		98%1,000.00 €~2,660.00 €Tue 22 Apr 25
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M-110
REF: TM-T15830CAS: 1395048-49-3 		98.30%To inquireTue 22 Apr 25
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SD-1029
REF: TM-T24774CAS: 118372-34-2 		- - -93.00 €~325.00 €Tue 22 Apr 25
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JAK3/BTK-IN-2
REF: TM-T9813CAS: 2674036-93-0 		99.64%235.00 €~2,419.00 €Tue 22 Apr 25
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Momelotinib Mesylate
REF: TM-T15037CAS: 1056636-07-7 		98%907.00 €~1,444.00 €Tue 22 Apr 25
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JAK-STAT-IN-1
REF: TM-T78607CAS: 1236666-76-4 		99.21%185.00 €~1,872.00 €Tue 22 Apr 25
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JAK-IN-30
REF: TM-T79235CAS: 2891469-99-9 		98%123.00 €~2,337.00 €Tue 22 Apr 25
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CX-6258
REF: TM-T1834CAS: 1202916-90-2 		95.88%37.00 €~658.00 €Tue 22 Apr 25
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JAK2-IN-9
REF: TM-T79581CAS: 2568842-26-0 		98%907.00 €~2,375.00 €Tue 22 Apr 25
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JAK-IN-28
REF: TM-T79116CAS: 2445500-22-9 		98%907.00 €~2,375.00 €Tue 22 Apr 25
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Ruxolitinib
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Ruxolitinib

CAS:941678-49-5
Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.
Formula:
C17H18N6
Purity:
100% - 99.99%
Color and Shape:
Solid
Molecular weight:
306.36

Ref: TM-T1829

5mg58.00 €
10mg74.00 €
25mg92.00 €
50mg116.00 €
100mg155.00 €
200mg245.00 €
500mg414.00 €
1mL*10mM (DMSO)65.00 €
Estimated delivery in United States, on Tuesday 11 Mar 2025
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Solcitinib
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Solcitinib

CAS:1206163-45-2
Solcitinib (GLPG-0778), a JAK1 inhibitor, may treat psoriasis, ulcerative colitis, and lupus.
Formula:
C22H23N5O2
Purity:
98.25% - 99.82%
Color and Shape:
Solid
Molecular weight:
389.45

Ref: TM-T3620

5mg50.00 €
10mg64.00 €
25mg90.00 €
50mg117.00 €
100mg187.00 €
200mg301.00 €
1mL*10mM (DMSO)51.00 €
Estimated delivery in United States, on Tuesday 11 Mar 2025
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Fosifidancitinib
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Fosifidancitinib

CAS:1237168-58-9
Fosifidancitinib is a potent inhibitor of JAK 1 and JAK 3.
Formula:
C21H21FN5O7P
Purity:
99.55%
Color and Shape:
Solid
Molecular weight:
505.39

Ref: TM-T38624

1mg87.00 €
2mg124.00 €
5mg187.00 €
10mg284.00 €
25mg452.00 €
50mg645.00 €
100mg867.00 €
200mg1,159.00 €
Estimated delivery in United States, on Tuesday 11 Mar 2025
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Oclacitinib maleate
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Oclacitinib maleate

CAS:1640292-55-2
Oclacitinib maleate is a selective JAK inhibitor (IC50: 10-99 nM; JAK1 cytokines: 36-249 nM), with …
Formula:
C15H23N5O2S·C4H4O4
Purity:
99.17%
Color and Shape:
Solid
Molecular weight:
453.51

Ref: TM-T6914

1mg39.00 €
2mg50.00 €
5mg79.00 €
10mg99.00 €
25mg170.00 €
50mg271.00 €
100mg457.00 €
1mL*10mM (DMSO)86.00 €
Estimated delivery in United States, on Tuesday 11 Mar 2025
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(Z)-SMI-4a
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(Z)-SMI-4a

CAS:438190-29-5
(Z)-SMI-4a (TCS PIM-1 4a) is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of …
Formula:
C11H6F3NO2S
Purity:
97.66% - 99.44%
Color and Shape:
Solid
Molecular weight:
273.23

Ref: TM-T3058

5mg51.00 €
10mg72.00 €
25mg144.00 €
50mg216.00 €
100mg324.00 €
200mg489.00 €
1mL*10mM (DMSO)51.00 €
Estimated delivery in United States, on Tuesday 11 Mar 2025
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Oclacitinib
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Oclacitinib

CAS:1208319-26-9
Oclacitinib (PF-03394197)(PF03394197) is a potent and selective JAKs inhibitor with IC50 of 10-99 nM; not …
Formula:
C15H23N5O2S
Purity:
98% - 98.12%
Color and Shape:
White To Off-White Solid
Molecular weight:
337.44

Ref: TM-T2012

5mg47.00 €
10mg60.00 €
25mg107.00 €
50mg169.00 €
100mg274.00 €
1mL*10mM (DMSO)50.00 €
Estimated delivery in United States, on Tuesday 11 Mar 2025
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AZD-1480
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AZD-1480

CAS:935666-88-9
AZD1480: JAK2 inhibitor, IC50 0.26 nM; selective vs Tyk2, JAK3; less on JAK1. Used in …
Formula:
C14H14ClFN8
Purity:
97.5% - 98.55%
Color and Shape:
Solid
Molecular weight:
348.77

Ref: TM-T3069

5mg57.00 €
10mg88.00 €
25mg140.00 €
50mgTo inquire
1mL*10mM (DMSO)59.00 €
Estimated delivery in United States, on Tuesday 11 Mar 2025
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JAK-IN-5 hydrochloride
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JAK-IN-5 hydrochloride

CAS:2751323-21-2
JAK-IN-5 hydrochloride is a JAK inhibitor [1].
Formula:
C27H32ClFN6O
Color and Shape:
Liquid
Molecular weight:
511.03

Ref: TM-T11710L

25mg1,539.00 €
50mg2,005.00 €
100mg2,992.00 €
Estimated delivery in United States, on Tuesday 11 Mar 2025
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NVP-BSK805
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NVP-BSK805

CAS:1092499-93-8
NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.
Formula:
C27H28F2N6O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
490.55

Ref: TM-T5049

1mg63.00 €
5mg131.00 €
10mg210.00 €
25mg410.00 €
Estimated delivery in United States, on Wednesday 19 Mar 2025
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JAK-IN-11
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JAK-IN-11

CAS:916742-11-5
JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the …
Formula:
C23H22FN5O4S
Purity:
99.57%
Color and Shape:
Solid
Molecular weight:
483.52

Ref: TM-T12549

1mg284.00 €
5mg568.00 €
10mg924.00 €
25mg1,681.00 €
50mg2,262.00 €
1mL*10mM (DMSO)645.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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discount label
JAK1-IN-4
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JAK1-IN-4

CAS:2091134-35-7
JAK1-IN-4 selectively blocks JAK1 (IC50 = 85 nM) over JAK2/JAK3 and halts STAT3 phosphorylation in …
Formula:
C26H32FN9O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
521.59

Ref: TM-T15606

25mg1,586.00 €
50mg2,072.00 €
100mg2,660.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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M-110
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M-110

CAS:1395048-49-3
M-110 selectively targets PIM kinases, best at PIM-3 (IC50=47nM), and inhibits prostate cancer cell growth …
Formula:
C22H28ClN5O3
Purity:
98.30%
Color and Shape:
Solid
Molecular weight:
445.94

Ref: TM-T15830

5mg64.00 €
10mg92.00 €
25mgTo inquire
50mgTo inquire
1mL*10mM (DMSO)64.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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SD-1029
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SD-1029

CAS:118372-34-2
SD-1029 is a JAK2 inhibitor and a novel Stat3 activation inhibitor that inhibits Stat3 phosphorylation …
Formula:
C25H32Br2Cl2N2O3
Color and Shape:
Solid
Molecular weight:
639.25

Ref: TM-T24774

1mg93.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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JAK3/BTK-IN-2
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JAK3/BTK-IN-2

CAS:2674036-93-0
JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.
Formula:
C25H32N8O2
Purity:
99.64%
Color and Shape:
Solid
Molecular weight:
476.57

Ref: TM-T9813

1mg235.00 €
5mg587.00 €
10mg835.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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Momelotinib Mesylate
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Momelotinib Mesylate

CAS:1056636-07-7
Momelotinib Mesylate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity …
Formula:
C24H26N6O5S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
510.57

Ref: TM-T15037

25mg1,444.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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JAK-STAT-IN-1
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JAK-STAT-IN-1

CAS:1236666-76-4
JAK-STAT-IN-1 is a specific JAK-STAT inhibitor indicated for the study of autoimmune diseases.
Formula:
C21H21N5O2
Purity:
99.21%
Color and Shape:
Liquid
Molecular weight:
375.42

Ref: TM-T78607

1mg185.00 €
5mg459.00 €
10mg657.00 €
25mg1,026.00 €
50mg1,415.00 €
100mg1,872.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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JAK-IN-30
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JAK-IN-30

CAS:2891469-99-9
JAK-IN-30 (compound 31) is a water-soluble inhibitor of Janus kinases (JAKs), demonstrating inhibitory potency with …
Formula:
C19H26N8S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
398.53

Ref: TM-T79235

1mg123.00 €
5mg465.00 €
10mg832.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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CX-6258
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CX-6258

CAS:1202916-90-2
CX-6258 is an orally valid Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor. It has good …
Formula:
C26H24ClN3O3
Purity:
95.88%
Color and Shape:
Solid
Molecular weight:
461.94

Ref: TM-T1834

1mg37.00 €
5mg80.00 €
10mg106.00 €
25mg208.00 €
50mg311.00 €
100mg472.00 €
200mg658.00 €
1mL*10mM (DMSO)81.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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JAK2-IN-9
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JAK2-IN-9

CAS:2568842-26-0
Compound A8, known as JAK2-IN-9, is a selective JAK2 inhibitor with an IC50 of 5 …
Formula:
C20H24N6O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
412.51

Ref: TM-T79581

25mg1,444.00 €
50mg1,882.00 €
100mg2,375.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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JAK-IN-28
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JAK-IN-28

CAS:2445500-22-9
JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of …
Formula:
C20H18ClN7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
407.86

Ref: TM-T79116

25mg1,444.00 €
50mg1,882.00 €
100mg2,375.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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