MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
Found 893 products of "MAPK"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
JIP-1 (153-163) acetate(438567-88-5 free base)
JNK peptide inhibitor. Mimics JIP-1 residues 153-163. Micromolar affinity, little effect on p38, ERK.Formula:C63H108N20O16Purity:92.89%Color and Shape:SolidMolecular weight:1401.65Maohuoside A
CAS:Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.Formula:C27H32O12Purity:98.91% - 99.57%Color and Shape:SolidMolecular weight:548.54Ref: TM-TN2081
1mg52.00€5mg116.00€10mg172.00€25mg266.00€50mg353.00€100mg803.00€200mg1,063.00€1mL*10mM (DMSO)142.00€Pluripotin
CAS:Pluripotin (SC1) (SC1), which keep embryonic stem cell (ESC) self-renewal, is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) andFormula:C27H25F3N8O2Purity:98.77% - 98.82%Color and Shape:SolidMolecular weight:550.53Ref: TM-T6948
1mg34.00€2mg48.00€5mg63.00€10mg88.00€25mg140.00€50mg207.00€100mg333.00€1mL*10mM (DMSO)74.00€ERK5-IN-1
CAS:ERK5-IN-1 is a potent ERK5 inhibitor (IC50: 87 nM). It also inhibits LRRK2[G2019S] (IC50: 26 nM).Formula:C25H29N7O2Purity:97.70%Color and Shape:SolidMolecular weight:459.54Plx-4032
CAS:Plx-4032 (Vemurafenib) is a small-molecule B-Raf inhibitor for the potential treatment of malignant melanoma.Formula:C23H18ClF2N3O3SPurity:98.53% - 99.36%Color and Shape:SolidMolecular weight:489.92PLX8394
CAS:Plixorafenib (PLX8394) is an orally active inhibitor of the serine/threonine protein kinase B-Raf (BRAF) protein.Cost-effective and quality-assured.Formula:C25H21F3N6O3SPurity:98.75% - >99.99%Color and Shape:SolidMolecular weight:542.53AS601245
CAS:AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.Formula:C20H16N6SPurity:98% - 99.02%Color and Shape:SolidMolecular weight:372.45Talmapimod
CAS:Talmapimod (SCIO-469): Oral ATP-competitive p38α inhibitor, IC50 = 9 nM (p38α), 90 nM (p38β), >2000-fold selectivity over 20 kinases.Formula:C27H30ClFN4O3Purity:98% - 99.9%Color and Shape:SolidMolecular weight:513Ref: TM-T12871
1mg50.00€2mg73.00€5mg109.00€10mg168.00€25mg358.00€50mg530.00€100mg758.00€1mL*10mM (DMSO)124.00€S6K-18
CAS:S6K-18, a highly selective S6K1 inhibitor, inhibits S6K1 with IC50 of 52nM.Formula:C17H18N4O3SPurity:98.99%Color and Shape:SolidMolecular weight:358.41Ref: TM-T22422
1mg39.00€5mg92.00€10mg138.00€25mg304.00€50mg424.00€100mg587.00€200mg792.00€1mL*10mM (DMSO)105.00€ML-098
CAS:ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).Formula:C19H19NO3Purity:99.06% - 99.23%Color and Shape:SolidMolecular weight:309.36Ref: TM-T4619
1mg37.00€2mg50.00€5mg66.00€10mg94.00€25mg190.00€50mg268.00€100mg374.00€500mg884.00€1mL*10mM (DMSO)84.00€APS-2-79 hydrochloride
CAS:APS-2-79 hydrochloride (APS-2-79 HCl) is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization.Formula:C23H21N3O3·HClPurity:98.64% - 99.55%Color and Shape:SolidMolecular weight:423.89K-Ras(G12C) inhibitor 9
CAS:K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).Formula:C16H21ClIN3O4SPurity:97.33% - 97.45%Color and Shape:SolidMolecular weight:513.78Ref: TM-T6556
1mg34.00€5mg78.00€10mg108.00€25mg215.00€50mg311.00€100mg425.00€200mg597.00€1mL*10mM (DMSO)108.00€Encorafenib
CAS:Encorafenib (LGX818) is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potential antineoplastic activity.Formula:C22H27ClFN7O4SPurity:99.51% - 99.83%Color and Shape:SolidMolecular weight:540.01Tizoxanide
CAS:Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.Formula:C10H7N3O4SPurity:98.89% - 99.28%Color and Shape:SolidMolecular weight:265.25(S)-AMG-510
CAS:(S)-AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C.Cost-effective and quality-assured.Formula:C30H30F2N6O3Purity:99.05% - 99.76%Color and Shape:SolidMolecular weight:560.594Ref: TM-T22258
2mg34.00€5mg50.00€10mg80.00€25mg147.00€50mg259.00€100mg404.00€500mg888.00€1mL*10mM (DMSO)73.00€PLX-4720
CAS:PLX-4720 is a potent and selective B-Raf (V600E) inhibitor designed to block the ATP-binding site of oncogenic B-Raf.Cost-effective and quality-assured.Formula:C17H14ClF2N3O3SPurity:97.78% - 99.83%Color and Shape:SolidMolecular weight:413.83APS6-45
CAS:APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.Formula:C23H16F8N4O3Purity:99.39%Color and Shape:SolidMolecular weight:548.39Ref: TM-T8843
2mg37.00€5mg84.00€10mg120.00€25mg236.00€50mg380.00€100mg583.00€200mg785.00€1mL*10mM (DMSO)92.00€XMD17-109
CAS:XMD17-109 (ERK5-IN-1) is a new selective ERK-5 inhibitor (EC50: 4.2 uM, HEK293 cells).
Formula:C36H46N8O3Purity:98.75% - 99.7%Color and Shape:SolidMolecular weight:638.8SHP389
CAS:SHP389 is a highly effective allosteric inhibitor of SHP2, inhibiting SHP2 and p-ERK, used in cancer research.Formula:C23H29ClN8O2Purity:98.24%Color and Shape:SolidMolecular weight:484.98ERK-IN-4
CAS:ERK-IN-4 is a cell-permeable ERK inhibitor with potential antiproliferative effects for the study of diseases caused by immune dysfunction.Formula:C14H17ClN2O3SPurity:98.92% - 99.84%Color and Shape:SolidMolecular weight:328.814Ref: TM-T36675
1mg46.00€2mg57.00€5mg93.00€10mg137.00€25mg219.00€50mg324.00€100mg484.00€1mL*10mM (DMSO)99.00€Raf inhibitor 1
CAS:B-Raf inhibitor 1 (B-Raf inhibitor 1) is a potent and selective B-Raf inhibitor.Formula:C26H19ClN8Purity:99.91%Color and Shape:SolidMolecular weight:478.94GW284543
CAS:GW284543 (UNC10225170) is a selective inhibitor of MEK5 .Formula:C23H20N2O3Purity:99.75%Color and Shape:SolidMolecular weight:372.42Ulixertinib hydrochloride
CAS:Ulixertinib hydrochloride (Ulixertinib HCl) is an ERK1/2 inhibitor with anticancer and antitumor activity that inhibits the NB cell cycle and promotes apoptosisFormula:C21H23Cl3N4O2Purity:99.85%Color and Shape:SolidMolecular weight:469.79TBAP-001
CAS:TBAP-001 is a RAF kinase inhibitor, with an IC50 of 62 nM in BRAF V600E kinase assay and an IC50 of 18 nM in Cell-Based Phosho-ERK Assay.Formula:C27H23F2N7O3Purity:99.58%Color and Shape:SolidMolecular weight:531.51Ref: TM-T9693
1mg46.00€5mg92.00€10mg147.00€25mg258.00€50mg386.00€100mg537.00€200mg710.00€1mL*10mM (DMSO)107.00€NCB-0846
CAS:NCB-0846 is an orally active TNIK inhibitor (IC50: 21 nM).Formula:C21H21N5O2Purity:97.04% - 99.89%Color and Shape:SolidMolecular weight:375.42AZD0022
CAS:AZD0022 is a selective, reversible, and orally active KRAS G12D inhibitor, exhibits tumour marker inhibition in PDAC and NSCLC models.Formula:C34H30F4N6OPurity:98.73%Color and Shape:SoildMolecular weight:614.64AMG410
CAS:AMG410 is a non-covalent, dual-modality KRAS inhibitor effective against both GDP (OFF) and GTP (ON) binding independently of the cell cycle and other mutants,Formula:C31H32ClF2N7O5Purity:98.01% - 99.84%Color and Shape:SoildMolecular weight:656.08Trametiglue
CAS:Trametiglue, a potent Trametinib derivative, selectively targets KSR-MEK and RAF-MEK through unique binding.Formula:C25H24FIN6O5SColor and Shape:SolidMolecular weight:666.46ASK1-IN-6
CAS:ASK1-IN-6 (Compound 32), a selective apoptosis signal-regulating kinase 1 (ASK1) inhibitor, exhibits an IC50 of 25 nM. This compound readily crosses the blood-brain barrier, as evidenced by rat pharmacokinetics showing a clearance/unchanged clearance rate of 1.6/56 L/h/kg and an unbound partition coefficient (Kp,uu) of 0.46. Additionally, ASK1-IN-6 demonstrates anti-inflammatory activity and effectively improves symptoms in the Alzheimer's Disease Tg4510 mouse model.Formula:C17H14F4N6O2Molecular weight:410.336H05
CAS:6H05 (K-Ras inhibitor) is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).Formula:C20H30ClN3O2S3Purity:98%Color and Shape:SolidMolecular weight:476.12Cephradine monohydrate
CAS:Cephradine monohydrate is a β-lactam cephalosporin antibiotic exhibiting broad-spectrum activity against Gram-positive and Gram-negative pathogens.Formula:C16H21N3O5SPurity:99.91%Color and Shape:SolidMolecular weight:367.42ETC-168
CAS:ETC-168 is a selective, orally active MNK inhibitor with IC50 values of 23 nM for MNK1 and 43 nM for MNK2. It demonstrates antiproliferative efficacy both in vivo and in vitro [1].Formula:C24H19N5O2Color and Shape:SolidMolecular weight:409.44FMK
CAS:FMK 是一种不可逆的 RSK2 抑制剂，能够共价修饰 RSK 的 C 末端区域。Formula:C18H19FN4O2Purity:99.71%Color and Shape:SolidMolecular weight:342.37Ref: TM-TQ0310
1mg74.00€2mg96.00€5mg168.00€10mg301.00€25mg512.00€50mg738.00€100mg1,035.00€500mg2,062.00€1mL*10mM (DMSO)187.00€SC-68376
CAS:SC-68376 is a potent, reversible, cell-permeable, ATP-competitive, and selective inhibitor of p38 MAP kinase.Formula:C15H12N2OPurity:98%Color and Shape:SolidMolecular weight:236.27Deltarasin
CAS:Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.Formula:C40H37N5OPurity:99.4%Color and Shape:SolidMolecular weight:603.75Cot inhibitor-2
CAS:Cot inhibitor-2: Potent, selective Tpl2/MAP3K8 blocker. IC50: 1.6 nM; hampers LPS-induced TNF-α, IC50: 0.3 μM. Orally active.Formula:C26H25Cl2FN8Purity:99.85%Color and Shape:SolidMolecular weight:539.43Ref: TM-T10866
1mg69.00€5mg149.00€10mg230.00€25mg485.00€50mg713.00€100mg1,018.00€200mg1,369.00€1mL*10mM (DMSO)172.00€PLX7904
CAS:PLX7904 (PB04), a selective RAF inhibitor, blocks ERK1/2 in mutant BRAF melanoma without activating it in RAS mutants.Formula:C24H22F2N6O3SPurity:99.51% - 99.66%Color and Shape:SolidMolecular weight:512.53Sulindac sulfide
CAS:Sulindac sulfide: NSAID targeting COX-1, inhibits Ras-Raf-1 and gamma-secretase (IC50: 20.2 μM), active sulinic acid metabolite.Formula:C20H17FO2SPurity:99.35%Color and Shape:SolidMolecular weight:340.41TAK1/MAP4K2 inhibitor 1
CAS:TAK1/MAP4K2 inhibitor 1 (compound 5) is a dual kinase inhibitor of TAK1 and MAP4K2 with IC50 values of 41.1 nM and 18.2 nM, respectively.Formula:C29H31F3N6O2Purity:98%Color and Shape:SolidMolecular weight:552.59GDC-0879
CAS:GDC-0879 (AR-00341677) is a novel, potent and selective B-Raf inhibitor with IC50 of 0.13 nM with activity against c-Raf as well.Formula:C19H18N4O2Purity:99.62%Color and Shape:SolidMolecular weight:334.37Ref: TM-T6320
1mg35.00€2mg50.00€5mg74.00€10mg105.00€25mg205.00€50mg334.00€100mg537.00€200mg765.00€1mL*10mM (DMSO)82.00€GGTI-286
CAS:GGTI-286: GGTase I inhibitor, cell-permeable, IC50=2μM. Strongly blocks Rap1A geranylation; less effective on H-Ras, Ras4B IC50=1μM.Formula:C23H31N3O3SColor and Shape:SolidMolecular weight:429.58RMM-46
CAS:RMM-46 is a reversible covalent inhibitor with high ligand efficiency and selectivity for MSK/RSK family kinases.Formula:C24H26N4O5Purity:98.89%Color and Shape:SolidMolecular weight:450.49KRas G12C inhibitor 3
CAS:KRas G12C inhibitor 3 is a compound that inhibits KRas G12C.Formula:C32H36ClN7O2Purity:98%Color and Shape:SolidMolecular weight:586.13Avutometinib potassium
CAS:Avutometinib potassium, a MEKi, blocks Delta and Omicron infection in airway cells, potentially lessening disease severity.Formula:C21H17FKN5O5SColor and Shape:SolidMolecular weight:509.55Tpl2-IN-I
CAS:Tpl2-IN-I is an inhibitor of tumour progression locus 2 (Tpl2) kinase.Formula:C21H14ClFN6Purity:98%Color and Shape:SolidMolecular weight:404.83NSC1011
CAS:NSC1011 is an inhibitor of ras converting enzyme 1 (Rce1).Formula:C23H18N2O3Purity:98%Color and Shape:SolidMolecular weight:370.4AZD6703 free base
CAS:AZD6703 is a potent, selective and reversible orally bioavailable inhibitor of p38 mitogen-activated protein kinase 14 (MAPK14).Formula:C24H27N5O2Color and Shape:SolidMolecular weight:417.5Kobe2601
CAS:Kobe2601 is a Kobe0065 and Kobe02602 water-soluble analog. It displays inhibitory activity towards Ras-Raf binding.Formula:C13H10FN5O4SPurity:98%Color and Shape:SolidMolecular weight:351.31GSK329
CAS:GSK329 selectively inhibits TNNI3K, showing cardioprotection in ischemic heart models.Formula:C19H14Cl2F3N5O2Purity:98%Color and Shape:SolidMolecular weight:472.25Ref: TM-T24109
1mg50.00€2mg72.00€5mg110.00€10mg173.00€25mg295.00€50mg424.00€100mg577.00€200mg778.00€1mL*10mM (DMSO)130.00€HCI-2184
CAS:HCI-2184 is an inhibitor of AXL kinase and Nek2 that acts by successfully mitigating drug resistance in bortezomib-resistant multiple myeloma.Formula:C23H28ClN7O2SPurity:98%Color and Shape:SolidMolecular weight:502.03GSK649A
CAS:GSK649A is a novel activator of Satellite Cell Proliferation, it could enhance repair of Damaged Muscle.Formula:C15H12ClFN6OSPurity:98%Color and Shape:SolidMolecular weight:378.81CP-281384
CAS:CP-281384 is a potent, p38alpha-selective inhibitor.Formula:C18H14F2N4OPurity:98%Color and Shape:SolidMolecular weight:340.33pan-KRAS-IN-16
CAS:3344 is an inhibitor of KRAS-effector interactions，with an affnity of 126nm.Formula:C24H26N2O3Purity:98%Color and Shape:SolidMolecular weight:390.47mSIRK
CAS:mSIRK (G-Protein βγ Binding Peptide) is an ERK1 and ERK2 dual activator that promotes alpha-subunit dissociation.Formula:C93H150N20O25Purity:99.26%Color and Shape:SolidMolecular weight:1948.31RBC6
CAS:RBC6 is an inhibitor of the binding of Ral to its effector RALBP1.Formula:C16H14Cl2N4O2Purity:98%Color and Shape:SolidMolecular weight:365.21MW108
CAS:MW108 is an active site targeted, CNS-active, p38αMAPK inhibitor.Formula:C21H19ClN4Color and Shape:SolidMolecular weight:362.86CP-944629
CAS:CP-944629 is a novel, potent, and selective inhibitor of p38alpha.Formula:C19H15F3N4OPurity:98%Color and Shape:SolidMolecular weight:372.34BNC-1
CAS:BNC-1 reduces amyloid in mice, enhances synapses by activating Elk-1.Formula:C16H14N2O3Purity:98%Color and Shape:SolidMolecular weight:282.29KRas G12C inhibitor 4
CAS:KRas G12C inhibitor 4 is a compound that inhibits KRas G12C.Formula:C33H38ClN7O2Purity:98%Color and Shape:SolidMolecular weight:600.15KRAS G12D inhibitor 10
CAS:KRAS G12D inhibitor 10 targets KRAS G12D in cancer research (WO2021108683A1, compound 34).Formula:C33H41ClN8O2Color and Shape:SolidMolecular weight:617.18ERK1/2 inhibitor 1
CAS:ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively.
Formula:C29H32ClN5O4Purity:98.81%Color and Shape:SolidMolecular weight:550.05PF-05381941
CAS:PF-05381941 is a selective and potent dual inhibitor of TAK1 and p38α that inhibits the kinase activity of TAK1 by binding to its active site.Formula:C27H26N6O2Purity:98.04%Color and Shape:SolidMolecular weight:466.53MEK-IN-1
CAS:MEK-IN-1 is a MEK inhibitor.Formula:C24H20N4O4Purity:98%Color and Shape:SolidMolecular weight:428.44KRAS G12C inhibitor 31
CAS:KRAS G12C inhibitor 31 is an inhibitor of KRAS G12C that can be used to study cancer.Formula:C25H22ClFN6O3Color and Shape:SolidMolecular weight:508.93PAF (C16)
CAS:PAF (C16) is a potent MAPK and MEK/ERK activator that induces increased vascular permeability.Formula:C26H54NO7PPurity:98%Color and Shape:SolidMolecular weight:523.68B-Raf IN 13
CAS:B-Raf IN 13 is a potent B-Raf inhibitor with anticancer activity.B-Raf IN 13 has an IC50 of 3.55 nM in the BRAF V600E enzyme assay.
Formula:C19H19ClFN3O4SPurity:99.41% - >99.99%Color and Shape:SoildMolecular weight:439.89(S)-CCG-1423
(S)-CCG-1423, a stereoisomer, inhibits Rho to block myocardin-related transcription factor A & serum response signaling.Formula:C18H13ClF6N2O3Purity:98%Color and Shape:SolidMolecular weight:454.8p38α inhibitor 2
CAS:P38α Inhibitor 2, a potent and selective inhibitor of p38α MAPK, exhibits a pIC50 value of 9.6.Formula:C27H33N5O3Color and Shape:SolidMolecular weight:475.58Cuspin-1
CAS:Cuspin-1, a small molecule, increases SMN levels by 50% in SMA by boosting ERK phosphorylation and Ras-Raf-MEK signaling.Formula:C13H10BrNOColor and Shape:SolidMolecular weight:276.13PD 334581
CAS:MEK1 inhibitorFormula:C20H19F3IN5O2Purity:98%Color and Shape:SolidMolecular weight:545.3EO 1428
CAS:p38α and p38β2 inhibitorFormula:C20H16BrClN2OPurity:98%Color and Shape:SolidMolecular weight:415.71L-167307
CAS:L-167307 is a p38 kinase inhibitor.Formula:C22H17FN2OSPurity:98%Color and Shape:SolidMolecular weight:376.45KRAS4b-IN-D14
CAS:KRAS4b-IN-D14 inhibits oncogenic KRAS4b, shrinks tumors, and induces cancer cell apoptosis.Formula:C24H24ClN5O4Color and Shape:SolidMolecular weight:481.93HPK1-IN-15
CAS:HPK1-IN-15 selectively inhibits HPK1, a MAP4K family kinase, potentially aiding in cancer treatment.Formula:C24H21ClF3N5Color and Shape:SolidMolecular weight:471.91KRAS G12D inhibitor 13
CAS:KRAS G12D inhibitor 13 targets KRAS G12D-mediated cancers with potency (WO2021108683A1, cmpd 142).Formula:C31H33F2N7O3Color and Shape:SolidMolecular weight:589.64KRAS G12C inhibitor 42
CAS:KRAS G12C inhibitor 42 targets KRAS G12C for potential cancer therapy. (Patent WO2020146613A1, compound 10)Formula:C33H34FN7O2Color and Shape:SolidMolecular weight:579.67p38-α MAPK-IN-4
CAS:p38-α MAPK-IN-4 (Compound 69) is a selective inhibitor of p38α MAPK, demonstrating potent inhibition with an IC50 of 1.5 μM.Formula:C17H13BrN2OColor and Shape:SolidMolecular weight:341.2LCRF-0004
CAS:LCRF-0004 inhibits RON kinase, key in KRAS-driven pancreatic cancer, reducing cell migration and enhancing chemo sensitivity.Formula:C28H18F4N6O2SColor and Shape:SolidMolecular weight:578.54SB-747651A
CAS:SB-747651A: ATP-competitive MSK1 inhibitor (IC50=11nM), affects N-terminal domain, also hinders MSK2, PKA, PKB, RSK, p70S6K.Formula:C16H22N8OPurity:98%Color and Shape:SolidMolecular weight:342.4KRAS G12C inhibitor 39
CAS:KRAS G12C inhibitor 39 effectively targets KRAS G12C, a key protein in cancer research.Formula:C37H43N9O2Color and Shape:SolidMolecular weight:645.8CBS-3595
CAS:CBS-3595: potent p38α MAPK/PDE-4 dual inhibitor, strong anti-inflammatory, low toxicity.Formula:C18H17FN4O2SPurity:98%Color and Shape:SolidMolecular weight:372.42SW-034538
CAS:SW-034538 is a TAO2 inhibitor (IC 50= 300 nM).Formula:C18H20N4O3S2Color and Shape:SolidMolecular weight:404.51MNK1/2-IN-5
CAS:MNK1/2-IN-5 is a potent and selective MNK1/2 inhibitor with anticancer activity and can be used to study solid tumors and hematological malignancies.Formula:C17H16N4O2Purity:98.04%Color and Shape:SolidMolecular weight:308.33Ref: TM-T60733
1mg60.00€2mg86.00€5mg130.00€10mg187.00€25mg338.00€50mg497.00€100mg708.00€200mg973.00€1mL*10mM (DMSO)138.00€GP17
CAS:GP17 is a type II kinase inhibitor of the IRE1α endoribonuclease that acts by targeting the ATP-binding pocket of IRE1α.Formula:C26H21F3N4OColor and Shape:SolidMolecular weight:462.47KB-5246
CAS:KB-5246, displays antibacterial activities.is a tetracyclic quinolone.Formula:C18H17ClFN3O4SPurity:98%Color and Shape:SolidMolecular weight:425.86SR-3306
CAS:SR-3306 is a brain-penetrant and selective pan-JNK (JNK1/2/3) inhibitor with IC50 values of 67 nM, 283 nM, 159 nM.Cost-effective and quality-assured.Formula:C28H26N8OPurity:99.38% - 99.71%Color and Shape:SolidMolecular weight:490.56Ref: TM-T16927
1mg49.00€5mg98.00€10mg152.00€25mg288.00€50mg520.00€100mg835.00€500mg1,674.00€1mL*10mM (DMSO)108.00€B-Raf IN 7
CAS:"B-Raf IN 7 inhibits B-Raf (IC50: 110.23 nM); fights colon, breast, liver, cervical, prostate cancers (IC50: 7.50-12.83 μM)."Formula:C15H16N6O3Color and Shape:SolidMolecular weight:328.33JNK-1-IN-1
CAS:JNK-1-IN-1 is an inhibitor specifically targeting JNK-1, also exhibiting inhibition of MKK7 with an IC50 value of 7.8μM.Formula:C24H22N6SColor and Shape:SolidMolecular weight:426.54Quazinone
CAS:Quazinone: PDE3 inhibitor, enhances heart muscle contractility, lowers blood pressure, and inhibits DNA synthesis in muscle cells. IC50 = 4.2 μM.Formula:C11H10ClN3OColor and Shape:SolidMolecular weight:235.67KRAS G12C inhibitor 22
CAS:KRAS G12C inhibitor 22 is a KRAS G12C inhibitor.Formula:C32H41N7O2Color and Shape:SolidMolecular weight:555.71GNE-1858
CAS:GNE-1858 inhibits HPK1; IC50: 1.9 nM for wild-type, 1.9 nM (HPK1-TSEE), 4.5 nM (HPK1-SA).Formula:C21H26F2N8Purity:99.36%Color and Shape:SolidMolecular weight:428.48Ref: TM-T11438
1mg163.00€5mg334.00€10mg500.00€25mg807.00€50mg1,099.00€100mg1,485.00€500mg2,962.00€1mL*10mM (DMSO)358.00€CAY10561
CAS:CAY10561: potent, selective ERK2 inhibitor (Ki=2nM); blocks cell proliferation; IC50 in COLO 205 cells: 0.54μM.Formula:C22H17Cl2FN4O2Color and Shape:SolidMolecular weight:459.3ADTL-EI1712
CAS:ADTL-EI1712: ERK1/2/5 inhibitor (ERK1 IC50=40.43nM, ERK5=64.5nM), blocks HL-60/MKN74 cell growth, not HeLa; effective in MKN74 mouse model.Formula:C22H18Cl2N4O2S2Color and Shape:SolidMolecular weight:505.44Angiogenesis inhibitor BT2
CAS:BT2 inhibits angiogenesis, vascular permeability by targeting ERK, FosB, VCAM-1, and related genes, affecting MEK1 and suppressing retinal markers.Formula:C18H18N2O4Color and Shape:SolidMolecular weight:326.35JX 401
CAS:JX 401 is a p38α inhibitor.Formula:C21H25NO2SPurity:98%Color and Shape:SolidMolecular weight:355.49K-Ras G12C-IN-3
CAS:K-Ras G12C-IN-3: novel, irreversible inhibitor of K-Ras G12C mutant protein for cancer treatment.Formula:C21H19Cl3N2O3Color and Shape:SolidMolecular weight:453.75SB 204900
CAS:SB 204900 inhibit the release of histamine and TNF-α from RBL-2H3 cells.Formula:C18H17NO2Color and Shape:SolidMolecular weight:279.33HPK1-IN-29
CAS:"HPK1-IN-29 suppresses HPK1, boosting anti-tumor immunity; potential for immune disease research."Formula:C26H18F3N5O2Color and Shape:SolidMolecular weight:489.45DDO3711
CAS:"DDO3711, a PHORC, links an ASK1 inhibitor to a PP5 activator, inhibiting ASK1 (IC50=164.1 nM), dephosphorylating p-ASK1, and showing anti-cancer potential."Formula:C42H41N9O6Color and Shape:SolidMolecular weight:767.83
