MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
Found 885 products of "MAPK"
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CAY10404
CAS:<p>CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.</p>Formula:C17H12F3NO3SPurity:99.02%Color and Shape:SolidMolecular weight:367.34N-tert-butyl-α-Phenylnitrone
CAS:<p>N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity.</p>Formula:C11H15NOPurity:99.46% - 99.84%Color and Shape:SolidMolecular weight:177.24Refametinib
CAS:<p>Refametinib (RDEA119) (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 (IC50: 19/47 nM).</p>Formula:C19H20F3IN2O5SPurity:99.53% - >99.99%Color and Shape:SolidMolecular weight:572.34UM-164
CAS:<p>UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.</p>Formula:C30H31F3N8O3SPurity:98.72% - 99.52%Color and Shape:SolidMolecular weight:640.68NG25 trihydrochloride
CAS:<p>NG25 trihydrochloride: kinase inhibitor for MAP4K2, TAK1, Src, LYN, Abl, CSK, FER, p38α; blocks TNF-α signals; impedes IFN secretion; anti-cancer properties.</p>Formula:C29H33Cl3F3N5O2Color and Shape:SolidMolecular weight:646.96JNK Inhibitor VIII
CAS:<p>JNK Inhibitor VIII (TCS JNK 6o) is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45 nM and 160 nM for JNK-1 and -2,</p>Formula:C18H20N4O4Purity:98.93%Color and Shape:SolidMolecular weight:356.38I-49 free base
<p>I-49 free base (Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-) is a novel</p>Formula:C23H26ClF3N4O2Purity:99.64% - 99.88%Color and Shape:SolidMolecular weight:482.92Ulixertinib
CAS:<p>Ulixertinib (VRT752271) (BVD-523, VRT752271) is an effective and reversible ERK1/ERK2 inhibitor. The IC50 of Ulixertinib is less than 0.3 nM for ERK2.</p>Formula:C21H22Cl2N4O2Purity:99.31% - 99.95%Color and Shape:SolidMolecular weight:433.33AD80
CAS:<p>AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.</p>Formula:C22H19F4N7OPurity:99.49% - 99.75%Color and Shape:SolidMolecular weight:473.43SB 239063
CAS:<p>SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.</p>Formula:C20H21FN4O2Purity:99.42% - 99.81%Color and Shape:SolidMolecular weight:368.4K-Ras(G12C) inhibitor 6
CAS:<p>Irreversible K-Ras(G12C) inhibitor 6 fully modifies the protein at 10 μM after 24h in vitro.</p>Formula:C17H22Cl2N2O3SPurity:89.07% - 97.09%Color and Shape:SolidMolecular weight:405.34VX-11e
CAS:<p>VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.</p>Formula:C24H20Cl2FN5O2Purity:98.92% - ≥98%Color and Shape:SolidMolecular weight:500.35AS601245
CAS:<p>AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.</p>Formula:C20H16N6SPurity:98% - 99.02%Color and Shape:SolidMolecular weight:372.45Butein
CAS:<p>Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.</p>Formula:C15H12O5Purity:98.76% - >99.99%Color and Shape:SolidMolecular weight:272.25D-JNKI-1 acetate
<p>D-JNKI-1 acetate (AM-111 acetate) is a highly potent and cell-permeable peptide inhibitor of JNK.</p>Formula:C166H290N66O42Purity:99.48%Color and Shape:SolidMolecular weight:3882.5Talmapimod
CAS:<p>Talmapimod (SCIO-469): Oral ATP-competitive p38α inhibitor, IC50 = 9 nM (p38α), 90 nM (p38β), >2000-fold selectivity over 20 kinases.</p>Formula:C27H30ClFN4O3Purity:98% - 99.9%Color and Shape:SolidMolecular weight:513Encorafenib
CAS:<p>Encorafenib (LGX818) is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potential antineoplastic activity.</p>Formula:C22H27ClFN7O4SPurity:99.51% - 99.83%Color and Shape:SolidMolecular weight:540.01CCT196969
CAS:<p>CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. It also inhibits SRC, LCK, and the p38 MAPKs.</p>Formula:C27H24FN7O3Purity:98.93% - 99.65%Color and Shape:SolidMolecular weight:513.52SD 0006
CAS:<p>SD 0006 (SD-06) is a MAPK p38 alpha inhibitor( IC50 : 110 nM) for the treatment of arthritis.</p>Formula:C20H20ClN5O2Purity:98.32%Color and Shape:SolidMolecular weight:397.86Cefotetan
CAS:<p>Cefotetan, a cephamycin antibiotic, fights various bacteria by disrupting cell wall synthesis.</p>Formula:C17H17N7O8S4Purity:95.72% - 99.38%Color and Shape:SolidMolecular weight:575.62ML-098
CAS:<p>ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).</p>Formula:C19H19NO3Purity:99.06% - 99.23%Color and Shape:SolidMolecular weight:309.36AZ7550
CAS:<p>AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).</p>Formula:C27H31N7O2Purity:97.07% - 99.75%Color and Shape:SolidMolecular weight:485.58Deltarasin HCl
CAS:<p>Deltarasin hinders KRAS-PDEδ, impairs cancer cell growth via a PDEδ pocket, disrupting RAS/RAF signaling and autophagy.</p>Formula:C40H37N5O·xHClColor and Shape:SolidMolecular weight:713.144GSK-114
CAS:<p>GSK-114, a TNNI3K inhibitor with a 25 nM IC50, is 40x more selective than B-Raf and good for in vivo studies.</p>Formula:C19H23N5O4SPurity:99.51%Color and Shape:SolidMolecular weight:417.48JNK-IN-7
CAS:<p>JNK-IN-7 (JNK inhibitor) is a selective JNK1/2/3 inhibitor (IC50: 1.54/1.99/0.75 nM).</p>Formula:C28H27N7O2Purity:98.02% - 99.53%Color and Shape:SolidMolecular weight:493.56K-Ras(G12C) inhibitor 9
CAS:<p>K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).</p>Formula:C16H21ClIN3O4SPurity:97.33% - 97.45%Color and Shape:SolidMolecular weight:513.78Pyridoxal 5'-phosphate hydrate
CAS:<p>Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,</p>Formula:C8H10NO6PPurity:97.52%Color and Shape:SolidMolecular weight:247.14PF-06260933
CAS:<p>PF-06260933 is a highly selective small-molecule MAP4K4 inhibitor with IC50s of 3.7 and 160 nM for kinase and cell, respectively.</p>Formula:C16H13ClN4Purity:99.63% - 99.97%Color and Shape:SolidMolecular weight:296.75APS-2-79
CAS:<p>APS-2-79: KSR-dependent MEK inhibitor, blocks ATP biotin at KSR2, IC50 of 120 nM, disrupts Ras-MAPK signaling.</p>Formula:C23H21N3O3Color and Shape:SolidMolecular weight:387.43Cerdulatinib hydrochloride
CAS:<p>Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.</p>Formula:C20H28ClN7O3SPurity:99.85%Color and Shape:SolidMolecular weight:482Raf inhibitor 1
CAS:<p>B-Raf inhibitor 1 (B-Raf inhibitor 1) is a potent and selective B-Raf inhibitor.</p>Formula:C26H19ClN8Purity:98.05%Color and Shape:SolidMolecular weight:478.94ERK-IN-4
CAS:<p>ERK-IN-4 is a cell-permeable ERK inhibitor with potential antiproliferative effects for the study of diseases caused by immune dysfunction.</p>Formula:C14H17ClN2O3SPurity:98.92% - 99.84%Color and Shape:SolidMolecular weight:328.814GW284543
CAS:<p>GW284543 (UNC10225170) is a selective inhibitor of MEK5 .</p>Formula:C23H20N2O3Purity:99.75%Color and Shape:SolidMolecular weight:372.42Ulixertinib hydrochloride
CAS:<p>Ulixertinib hydrochloride (Ulixertinib HCl) is an ERK1/2 inhibitor with anticancer and antitumor activity that inhibits the NB cell cycle and promotes apoptosis</p>Formula:C21H23Cl3N4O2Purity:99.85%Color and Shape:SolidMolecular weight:469.79TBAP-001
CAS:<p>TBAP-001 is a RAF kinase inhibitor, with an IC50 of 62 nM in BRAF V600E kinase assay and an IC50 of 18 nM in Cell-Based Phosho-ERK Assay.</p>Formula:C27H23F2N7O3Purity:99.58%Color and Shape:SolidMolecular weight:531.51NCB-0846
CAS:<p>NCB-0846 is an orally active TNIK inhibitor (IC50: 21 nM).</p>Formula:C21H21N5O2Purity:97.04% - 99.89%Color and Shape:SolidMolecular weight:375.42VX-702
CAS:<p>VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.</p>Formula:C19H12F4N4O2Purity:99% - >99.99%Color and Shape:SolidMolecular weight:404.32AMG410
CAS:<p>AMG410 is a non-covalent, dual-modality KRAS inhibitor effective against both GDP (OFF) and GTP (ON) binding independently of the cell cycle and other mutants,</p>Formula:C31H32ClF2N7O5Purity:98.01% - 99.84%Color and Shape:SoildMolecular weight:656.08Trametiglue
CAS:<p>Trametiglue, a potent Trametinib derivative, selectively targets KSR-MEK and RAF-MEK through unique binding.</p>Formula:C25H24FIN6O5SColor and Shape:SolidMolecular weight:666.46AZD0022
CAS:<p>AZD0022 is a selective, reversible, and orally active KRAS G12D inhibitor, exhibits tumour marker inhibition in PDAC and NSCLC models.</p>Formula:C34H30F4N6OPurity:98.73%Color and Shape:SoildMolecular weight:614.64Deltarasin
CAS:<p>Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.</p>Formula:C40H37N5OPurity:99.4%Color and Shape:SolidMolecular weight:603.75Cephradine monohydrate
CAS:<p>Cephradine monohydrate is a β-lactam cephalosporin antibiotic exhibiting broad-spectrum activity against Gram-positive and Gram-negative pathogens.</p>Formula:C16H21N3O5SPurity:99.91%Color and Shape:SolidMolecular weight:367.426H05
CAS:<p>6H05 (K-Ras inhibitor) is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).</p>Formula:C20H30ClN3O2S3Purity:98%Color and Shape:SolidMolecular weight:476.12ETC-168
CAS:<p>ETC-168 is a selective, orally active MNK inhibitor with IC50 values of 23 nM for MNK1 and 43 nM for MNK2. It demonstrates antiproliferative efficacy both in vivo and in vitro [1].</p>Formula:C24H19N5O2Color and Shape:SolidMolecular weight:409.44SC-68376
CAS:<p>SC-68376 is a potent, reversible, cell-permeable, ATP-competitive, and selective inhibitor of p38 MAP kinase.</p>Formula:C15H12N2OPurity:98%Color and Shape:SolidMolecular weight:236.27FMK
CAS:<p>FMK 是一种不可逆的 RSK2 抑制剂，能够共价修饰 RSK 的 C 末端区域。</p>Formula:C18H19FN4O2Purity:99.71%Color and Shape:SolidMolecular weight:342.37PLX7904
CAS:<p>PLX7904 (PB04), a selective RAF inhibitor, blocks ERK1/2 in mutant BRAF melanoma without activating it in RAS mutants.</p>Formula:C24H22F2N6O3SPurity:99.51% - 99.66%Color and Shape:SolidMolecular weight:512.53Sulindac sulfide
CAS:<p>Sulindac sulfide: NSAID targeting COX-1, inhibits Ras-Raf-1 and gamma-secretase (IC50: 20.2 μM), active sulinic acid metabolite.</p>Formula:C20H17FO2SPurity:99.35%Color and Shape:SolidMolecular weight:340.41ERK5-IN-4
CAS:<p>ERK5-IN-4 (34b) is a potent, specific ERK5 inhibitor; IC50: 77 nM full-length, 300 nM ΔTAD in HEK293 cells.</p>Formula:C16H11Cl2FN4O2Color and Shape:SolidMolecular weight:381.19BRAF inhibitor
CAS:<p>BRAF inhibitor is an inhibitor of B-Raf.</p>Formula:C22H18F2N4O3SPurity:98.2% - 98.41%Color and Shape:SolidMolecular weight:456.47ERK1/2 inhibitor 1
CAS:<p>ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively.</p>Formula:C29H32ClN5O4Purity:98.81%Color and Shape:SolidMolecular weight:550.05PF-05381941
CAS:<p>PF-05381941 is a selective and potent dual inhibitor of TAK1 and p38α that inhibits the kinase activity of TAK1 by binding to its active site.</p>Formula:C27H26N6O2Purity:98.04%Color and Shape:SolidMolecular weight:466.53MEK-IN-1
CAS:<p>MEK-IN-1 is a MEK inhibitor.</p>Formula:C24H20N4O4Purity:98%Color and Shape:SolidMolecular weight:428.44PAF (C16)
CAS:<p>PAF (C16) is a potent MAPK and MEK/ERK activator that induces increased vascular permeability.</p>Formula:C26H54NO7PPurity:98%Color and Shape:SolidMolecular weight:523.68B-Raf IN 13
CAS:<p>B-Raf IN 13 is a potent B-Raf inhibitor with anticancer activity.B-Raf IN 13 has an IC50 of 3.55 nM in the BRAF V600E enzyme assay.</p>Formula:C19H19ClFN3O4SPurity:99.41% - >99.99%Color and Shape:SoildMolecular weight:439.89KRAS G12D inhibitor 10
CAS:<p>KRAS G12D inhibitor 10 targets KRAS G12D in cancer research (WO2021108683A1, compound 34).</p>Formula:C33H41ClN8O2Color and Shape:SolidMolecular weight:617.18GGTI-286
CAS:<p>GGTI-286: GGTase I inhibitor, cell-permeable, IC50=2μM. Strongly blocks Rap1A geranylation; less effective on H-Ras, Ras4B IC50=1μM.</p>Formula:C23H31N3O3SColor and Shape:SolidMolecular weight:429.58MCP110
CAS:<p>MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.</p>Formula:C33H36N2O3Purity:97.23%Color and Shape:OilMolecular weight:508.65KYA1797
CAS:<p>KYA1797 inhibits Wnt/ß-catenin, targeting axin, and promotes ß-catenin/Ras decay, halting APC/KRAS mutant CRC growth.</p>Formula:C17H12N2O6S2Purity:98%Color and Shape:SolidMolecular weight:404.42RSK2-IN-2
CAS:<p>RSK2-IN-2 (Compound 25) is a reversible covalent inhibitor of the RPS6KA3 ( RSK2 ) kinase which also inhibits MSK1, MSK2, and RSK3 [1].</p>Formula:C16H11N5OColor and Shape:SolidMolecular weight:289.29GABAB receptor antagonist 1
CAS:<p>(E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.GABAB receptor antagonist 1 is a selective</p>Formula:C18H24O4Purity:98%Color and Shape:SolidMolecular weight:304.38B-Raf IN 8
CAS:<p>B-Raf IN 8: strong B-Raf inhibitor (70.65 nM IC50); combats liver, colon, breast & prostate cancer with IC50s from 9.78 to 29.85 μM.</p>Formula:C18H17N3O2Color and Shape:SolidMolecular weight:307.35HPK1-IN-24
CAS:<p>HPK1-IN-24 (example 51) has potential to be used in the cancer research which is an inhibitor of hematopoietic progenitor kinase 1 (HPK1) (Ki = 100 nM) [1].</p>Formula:C19H14FN5Color and Shape:SolidMolecular weight:331.35UC-857993
CAS:<p>UC-857993 is a selective SOS1-Ras inhibitor with a Kd of 14.7 μM that inhibits ERK, Ras, and reduces MEF growth.</p>Formula:C25H22ClNO2Color and Shape:SolidMolecular weight:403.9JNK3 inhibitor-2
CAS:<p>JNK3 inhibitor-2: selectively inhibits JNK3 (IC50 = 0.25 μM); less effective on JNK1/JNK2 (>100 μM); targets DDR1 and EGFR mutations.</p>Formula:C20H14N2O2Color and Shape:SolidMolecular weight:314.34Tpl2 Kinase Inhibitor 1
CAS:<p>Tpl2 Kinase Inhibitor 1 is an effective and selective Tpl2 inhibitor.</p>Formula:C21H14ClFN6Purity:98%Color and Shape:SolidMolecular weight:404.83SX 011
CAS:<p>SX 011 is a p38α inhibitor.</p>Formula:C26H27ClFN3O3Purity:98%Color and Shape:SolidMolecular weight:483.96KRAS inhibitor-7
CAS:<p>KRAS inhibitor-7 is a potent KRAS G12C inhibitor.</p>Formula:C26H27ClF2N6O2Purity:98%Color and Shape:SolidMolecular weight:528.98HPK1-IN-25
CAS:<p>HPK1-IN-25, an HPK1 inhibitor, IC50 129 nM, may aid cancer research.</p>Formula:C23H25N5OColor and Shape:SolidMolecular weight:387.48KRAS G12C inhibitor 43
CAS:<p>KRAS G12C inhibitor 43 strongly blocks KRAS G12C, H358 cell growth (IC50: 0.001-1μM), less effective on A549, HCC cells (IC50>1μM).</p>Formula:C33H35N7O3Color and Shape:SolidMolecular weight:577.68GGTI-286 hydrochloride
CAS:<p>GGTI-286 HCl strongly inhibits GGTase I (IC50: 2 μM) and K-Ras4B farnesylation (IC50: 1 μM).</p>Formula:C23H32ClN3O3SColor and Shape:SolidMolecular weight:466.04SMAP-2
CAS:<p>SMAP-2: oral PP2A activator, targets Aα subunit, halts KRAS-mutant lung cancer growth.</p>Formula:C27H27F3N2O4SPurity:98%Color and Shape:SolidMolecular weight:532.57HPK1-IN-26
CAS:<p>HPK1-IN-26, from WO2021254118A1, is a potent dual HPK1/GLK inhibitor for studying animal infections.</p>Formula:C19H21N5OSColor and Shape:SolidMolecular weight:367.47ZINC09659342
CAS:<p>ZINC09659342 (compound 13) is an inhibitor of Lbc-RhoA interaction (IC50: 3.6 μM).</p>Formula:C23H15F3N2O4Color and Shape:SolidMolecular weight:440.37NSC-658497
CAS:<p>NSC-658497 is a SOS1-Ras interaction inhibitor that acts by dose-dependently inhibiting SOS1 GEF activity.</p>Formula:C20H10N2O6S2Purity:98%Color and Shape:SolidMolecular weight:438.43SR 3576
CAS:<p>JNK3 inhibitor, potent and selective</p>Formula:C27H27N5O5Purity:98%Color and Shape:SolidMolecular weight:501.53CAY10561
CAS:<p>CAY10561: potent, selective ERK2 inhibitor (Ki=2nM); blocks cell proliferation; IC50 in COLO 205 cells: 0.54μM.</p>Formula:C22H17Cl2FN4O2Color and Shape:SolidMolecular weight:459.3KRAS G12C inhibitor 22
CAS:<p>KRAS G12C inhibitor 22 is a KRAS G12C inhibitor.</p>Formula:C32H41N7O2Color and Shape:SolidMolecular weight:555.71Quazinone
CAS:<p>Quazinone: PDE3 inhibitor, enhances heart muscle contractility, lowers blood pressure, and inhibits DNA synthesis in muscle cells. IC50 = 4.2 μM.</p>Formula:C11H10ClN3OColor and Shape:SolidMolecular weight:235.67SB-747651A
CAS:<p>SB-747651A: ATP-competitive MSK1 inhibitor (IC50=11nM), affects N-terminal domain, also hinders MSK2, PKA, PKB, RSK, p70S6K.</p>Formula:C16H22N8OPurity:98%Color and Shape:SolidMolecular weight:342.4EO 1428
CAS:<p>p38α and p38β2 inhibitor</p>Formula:C20H16BrClN2OPurity:98%Color and Shape:SolidMolecular weight:415.71PD 334581
CAS:<p>MEK1 inhibitor</p>Formula:C20H19F3IN5O2Purity:98%Color and Shape:SolidMolecular weight:545.3p38α inhibitor 2
CAS:<p>P38α Inhibitor 2, a potent and selective inhibitor of p38α MAPK, exhibits a pIC50 value of 9.6.</p>Formula:C27H33N5O3Color and Shape:SolidMolecular weight:475.58pan-KRAS-IN-16
CAS:<p>3344 is an inhibitor of KRAS-effector interactions，with an affnity of 126nm.</p>Formula:C24H26N2O3Purity:98%Color and Shape:SolidMolecular weight:390.47B-Raf IN 6
CAS:<p>B-Raf IN 6: potent B-Raf kinase inhibitor, IC50 of 1.7 nM, doesn't target PXR, metabolically stable, potential in cancer research.</p>Formula:C24H21F3N6O2S2Color and Shape:SolidMolecular weight:546.59(R)-CE3F4
CAS:<p>(R)-CE3F4 is a selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1)(IC50 of 4.2 μM),</p>Formula:C11H10Br2FNOColor and Shape:SolidMolecular weight:351.01SR-3737
CAS:<p>SR-3737 is potent both JNK3 and p38 inhibitor.</p>Formula:C29H25FN4O4Purity:98%Color and Shape:SolidMolecular weight:512.53TOPK-p38/JNK-IN-1
CAS:<p>TOPK-p38/JNK-IN-1 (Compound B12) is an orally active inhibitor of the TOPK-p38/JNK signaling pathway, with an IC50 value of 2.14 μM for the inhibition of NO</p>Formula:C17H15F3N2O4Color and Shape:SolidMolecular weight:368.31B-Raf IN 7
CAS:<p>"B-Raf IN 7 inhibits B-Raf (IC50: 110.23 nM); fights colon, breast, liver, cervical, prostate cancers (IC50: 7.50-12.83 μM)."</p>Formula:C15H16N6O3Color and Shape:SolidMolecular weight:328.33KB-5246
CAS:<p>KB-5246, displays antibacterial activities.is a tetracyclic quinolone.</p>Formula:C18H17ClFN3O4SPurity:98%Color and Shape:SolidMolecular weight:425.86KRas G12C inhibitor 4
CAS:<p>KRas G12C inhibitor 4 is a compound that inhibits KRas G12C.</p>Formula:C33H38ClN7O2Purity:98%Color and Shape:SolidMolecular weight:600.15Avutometinib potassium
CAS:<p>Avutometinib potassium, a MEKi, blocks Delta and Omicron infection in airway cells, potentially lessening disease severity.</p>Formula:C21H17FKN5O5SColor and Shape:SolidMolecular weight:509.553,4-Dephostatin
CAS:<p>3,4-Dephostatin is an inhibitor of the interactions of CFTR-associated ligand (CAL) and PSD-95/Dlg1/ZO-1 (PDZ) domain.</p>Formula:C7H8N2O3Color and Shape:SolidMolecular weight:168.15ERK5-IN-3
CAS:<p>ERK5-IN-3 inhibits ERK5 strongly (IC50: 6 nM) and hampers Hela cell growth (IC50: 31 nM).</p>Formula:C24H23Cl2FN4O2Color and Shape:SolidMolecular weight:489.37Ras modulator-1
CAS:<p>Ras modulator-1 is a modulator of Ras.</p>Formula:C29H21N5O4SColor and Shape:SolidMolecular weight:535.57KRas G12C inhibitor 3
CAS:<p>KRas G12C inhibitor 3 is a compound that inhibits KRas G12C.</p>Formula:C32H36ClN7O2Purity:98%Color and Shape:SolidMolecular weight:586.13MW108
CAS:<p>MW108 is an active site targeted, CNS-active, p38αMAPK inhibitor.</p>Formula:C21H19ClN4Color and Shape:SolidMolecular weight:362.86(S)-CCG-1423
<p>(S)-CCG-1423, a stereoisomer, inhibits Rho to block myocardin-related transcription factor A & serum response signaling.</p>Formula:C18H13ClF6N2O3Purity:98%Color and Shape:SolidMolecular weight:454.8K-Ras G12C-IN-3
CAS:<p>K-Ras G12C-IN-3: novel, irreversible inhibitor of K-Ras G12C mutant protein for cancer treatment.</p>Formula:C21H19Cl3N2O3Color and Shape:SolidMolecular weight:453.75ML 3403
CAS:<p>p38 MAPK inhibitor; IC50: 0.38μM. Reduces IL-1β & TNF-α release in PBMC assay; IC50: 0.039μM & 0.16μM.</p>Formula:C23H21FN4SColor and Shape:SolidMolecular weight:404.5
