p38 MAPK
p38 MAPKs are a subgroup of MAPKs that respond to stress signals and are involved in the regulation of inflammation, cell differentiation, apoptosis, and autophagy. p38 MAPK signaling is crucial in immune responses and is implicated in various diseases, including chronic inflammatory conditions, cancer, and neurodegenerative disorders. At CymitQuimica, we provide a comprehensive range of p38 MAPK inhibitors and modulators to support your research in inflammation, stress response, and therapeutic development.
Found 117 products of "p38 MAPK"
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MW-150
CAS:<p>MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.</p>Formula:C24H23N5Purity:97.35% - 99.27%Color and Shape:SolidMolecular weight:381.47Isoliquiritin apioside
CAS:<p>Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.</p>Formula:C26H30O13Purity:98.84% - 99.27%Color and Shape:SolidMolecular weight:550.51Esculin
CAS:<p>Esculin (Aesculin) is a glucoside found in horse chestnuts.</p>Formula:C15H16O9Purity:97.93% - 99.83%Color and Shape:Cream PowderMolecular weight:340.28Doramapimod
CAS:<p>Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.</p>Formula:C31H37N5O3Purity:97.14% - 98.80%Color and Shape:SolidMolecular weight:527.66Bakuchiol
CAS:<p>Bakuchiol: anti-tumor, anti-helminthic, DNA polymerase1 inhibitor, cytotoxic, and anti-bacterial, may prevent dental caries.</p>Formula:C18H24OPurity:98.04% - 99.05%Color and Shape:Brownish Yellow Liquid ViscousMolecular weight:256.38PH-797804
CAS:<p>PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2.</p>Formula:C22H19BrF2N2O3Purity:97.90% - 98.27%Color and Shape:SolidMolecular weight:477.3Dehydrocorydaline
CAS:<p>1.</p>Formula:C22H24NO4Purity:99.84%Color and Shape:SolidMolecular weight:366.43Bisabolangelone
CAS:<p>Bisabolangelone: anti-tumor, anti-inflammatory, anti-microbial, antioxidant, blocks MAPK/NF-κB in dendritic cells.</p>Formula:C15H20O3Purity:98.91%Color and Shape:SolidMolecular weight:248.32SM-7368
CAS:<p>The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.</p>Formula:C10H5ClN4O5SPurity:99.64%Color and Shape:SolidMolecular weight:328.69AMG 900
CAS:<p>AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.</p>Formula:C28H21N7OSPurity:98.4% - 99.51%Color and Shape:SolidMolecular weight:503.58SD-169
CAS:<p>SD-169 (SD 169) is a selective and ATP competitive the MAP kinases p38α and p38β inhibitor.</p>Formula:C9H8N2OPurity:98.6%Color and Shape:SolidMolecular weight:160.17Afatinib
CAS:<p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>Formula:C24H25ClFN5O3Purity:98.56% - 99.9%Color and Shape:Off-White SolidMolecular weight:485.94N-Feruloyloctopamine
CAS:<p>N-Feruloyloctopamine is a natural product.</p>Formula:C18H19NO5Purity:99.70%Color and Shape:SolidMolecular weight:329.35Sesamolin
CAS:<p>Sesamolin and sesamin guard nerves, reduce microglia damage by blocking p38 MAPK and caspase-3, and curb nitric oxide in stimulated cells.</p>Formula:C20H18O7Purity:98.77% - 99.04%Color and Shape:SolidMolecular weight:370.35Pamapimod
CAS:<p>Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.</p>Formula:C19H20F2N4O4Purity:99.52% - 99.99%Color and Shape:SolidMolecular weight:406.38Losmapimod
CAS:<p>Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).</p>Formula:C22H26FN3O2Purity:98.35% - 99.89%Color and Shape:SolidMolecular weight:383.46RWJ-67657
CAS:<p>RWJ-67657 is a selective oral p38α/β MAPK inhibitor with IC50s of 1/11μM; inactive on p38γ/δ with cardioprotection.</p>Formula:C27H24FN3OPurity:99.66%Color and Shape:SolidMolecular weight:425.5Sertaconazole
CAS:<p>Sertaconazole is a broad-spectrum antifungal.</p>Formula:C20H15Cl3N2OSPurity:99.483%Color and Shape:SolidMolecular weight:437.77Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Formula:C51H82O21Purity:99.51% - 99.63%Color and Shape:SolidMolecular weight:1031.18Talmapimod
CAS:<p>Talmapimod (SCIO-469): Oral ATP-competitive p38α inhibitor, IC50 = 9 nM (p38α), 90 nM (p38β), >2000-fold selectivity over 20 kinases.</p>Formula:C27H30ClFN4O3Purity:98% - 99.9%Color and Shape:SolidMolecular weight:513
