Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(93 products)
- Adiponectin receptor(5 products)
- CFTR(64 products)
- CGRP Receptor(52 products)
- Calcium Channel(496 products)
- Chloride channel(49 products)
- GABA Receptor(336 products)
- Monoamine Transporter(23 products)
- Monocarboxylate transporter(17 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(8 products)
- OAT(27 products)
- OCT(7 products)
- P-gp(53 products)
- Potassium Channel(277 products)
- Proton pump(39 products)
- SGLT(30 products)
- Sodium Channel(202 products)
- TRP/TRPV Channel(93 products)
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Found 2290 products of "Membrane Transporter/Ion Channel"
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P-gp modulator 3
<p>P-gp modulator 3 (Compound 37) is a potent, competitive, metabotropic P-glycoprotein (P-gp) modulator.</p>Formula:C31H37N3O5Color and Shape:SolidMolecular weight:531.64(R)-Duloxetine
CAS:<p>(R)-Duloxetine, an isomer of Duloxetine, induces tonic and use-dependent blockade of neuronal Na+ channels. This compound is utilized in pain research.</p>Formula:C18H19NOSColor and Shape:SolidMolecular weight:297.42Opakalim
CAS:<p>Opakalim is an activator of potassium channels (potassium channel) and exhibits anticonvulsant activity.</p>Formula:C18H22F2N4OColor and Shape:SolidMolecular weight:348.39P-gp modulator 1
CAS:<p>P-gp modulator 1 is a high affinity and orally available P-glycoprotein (Pgp) modulator</p>Formula:C41H72N2O6Purity:98%Color and Shape:SolidMolecular weight:689.02Cav 3.2 inhibitor 3
<p>Cav 3.2 inhibitor 3 is a potent inhibitor of the Cav3.2 T-type Ca2+channel (IC50: 0.1534 μM) and has a low binding affinity for D2 receptors.</p>Formula:C32H37N3O2Color and Shape:SolidMolecular weight:495.66KPH2f
CAS:<p>KPH2f: dual URAT1/GLUT9 inhibitor, orally active, IC50: 0.24μM (URAT1), 9.37μM (GLUT9), minimal OAT1/ABCG2 impact.</p>Formula:C24H16N3NaO2SColor and Shape:SolidMolecular weight:433.46DS88790512
CAS:<p>DS88790512, IC50 at 11 nM, is an effective, selective, oral bioeffective TRPC6 inhibitor.</p>Formula:C22H29N3O2Purity:98%Color and Shape:SolidMolecular weight:367.484α-PDD
CAS:<p>4alpha-PDD activates transient receptor potential vanilloid 4 (TRPV4) channels and is inactive for signaling through PKC.</p>Formula:C40H64O8Color and Shape:SolidMolecular weight:672.93Onfasprodil
CAS:<p>Onfasprodil, NR2B inhibitor & GABA regulator, potential for Alzheimer's research. (Patent CN111481543A)</p>Formula:C20H23FN2O3Color and Shape:SolidMolecular weight:358.41Valbenazine tosylate
CAS:<p>Valbenazine tosylate, the tosylate salt of valbenazine, is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no</p>Formula:C38H54N2O10S2Purity:98%Color and Shape:SolidMolecular weight:762.97WS-898
<p>WS-898 boosts paclitaxel efficacy in resistant cells by inhibiting ABCB1; IC50: SW620/Ad300 - 5.0 nM, KB-C2 - 3.67 nM, HEK293/ABCB1 - 3.68 nM.</p>Formula:C33H25N7OSColor and Shape:SolidMolecular weight:567.66(RS)-AMPA
CAS:<p>(RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid.</p>Formula:C7H10N2O4Purity:98%Color and Shape:SolidMolecular weight:186.17NYX-2925
CAS:<p>NYX-2925, an oral NMDAR modulator, enhances Src in mPFC. No CAMKII impact or addictive/sedative effects. Useful for CNS disorder studies.</p>Formula:C14H23N3O4Color and Shape:SolidMolecular weight:297.35Ro 0437626
CAS:<p>P2X1 purinergic receptor antagonist</p>Formula:C27H35N5O4SPurity:98%Color and Shape:SolidMolecular weight:525.66TRPV1 antagonist 3
<p>TRPV1 antagonist 3 (7q) strongly blocks TRPV1 at 2.66 nM IC50, is selective, 60% bioavailable, and crosses the blood-brain barrier.</p>Formula:C23H25N3OSColor and Shape:SolidMolecular weight:391.53KCa2 channel modulator 2
Compound 2q is a potent, subtype-selective K/Ca 2 modulator, effective on human K Ca 2.3 and rat K Ca 2.2a with EC50s of 0.60 μM and 0.64 μM.Formula:C16H15ClFN5Color and Shape:SolidMolecular weight:331.78DFBTA
<p>DFBTA inhibits ANO1 with IC50 of 24 nM, effectively treating inflammatory pain orally.</p>Formula:C18H10ClF2NO3SColor and Shape:SolidMolecular weight:393.79Blixeprodil
CAS:<p>Blixeprodil (GM-1020) is an orally active NMDA receptor antagonist with an affinity of Ki = 3.25 µM in rat cortical tissue. It inhibits NR1/2A-NMDAR-mediated currents in HEK293 cells with an IC50 of 1.192 µM. Blixeprodil demonstrates antidepressant effects in rat models and exhibits blood-brain barrier permeability.</p>Formula:C13H16FNOColor and Shape:SolidMolecular weight:221.271ABCG2-IN-4
CAS:<p>ABCG2-IN-4 (Compound K31) is an orally active ABCG2 inhibitor that reduces the release of Protoporphyrin IX (PPIX) from red blood cells into the plasma and prevents phototoxicity. In mouse models, ABCG2-IN-4 also demonstrates anti-inflammatory and antioxidant properties.</p>Formula:C24H32N4O4Color and Shape:SolidMolecular weight:440.535Coleon-U-quinone
CAS:<p>Coleon-U-quinone, a P-gp inhibitor, reduces cancer cell viability and enhances Doxorubicin sensitivity in resistant cells.</p>Formula:C20H24O5Color and Shape:SolidMolecular weight:344.4IAA65
CAS:<p>IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1].</p>Formula:C16H13F6NO2Color and Shape:SolidMolecular weight:365.27VU0463271 quarterhydrate
<p>VU0463271 quarterhydrate is a potent KCC2 antagonist, with an IC 50 of 61 nM [1].</p>Formula:C19H20N4O2S2Color and Shape:SolidMolecular weight:387BMS-986163
CAS:<p>BMS-986163, a prodrug, quickly becomes BMS-986169, a GluN2B inhibitor (Ki=4 nM, IC50=24 nM).</p>Formula:C23H28FN2O5PPurity:98%Color and Shape:SolidMolecular weight:462.45V-ATPase-IN-1
CAS:<p>V-ATPase-IN-1 (Compound 3b-03) is an inhibitor of Vacuolar-type H+-ATPases (V-ATPase), exhibiting an inhibition constant (IC50) of 194.80 μM and effectively targeting the V-ATPase subunit A with a dissociation constant (Kd) of 0.803 μM. This compound demonstrates insecticidal activity against M. separata (LC50 = 2.64 mM), aiding in the development of chemical insecticides.</p>Formula:C21H20ClNO2Color and Shape:SolidMolecular weight:353.84(S)-Albuterol
CAS:<p>(S)-Albuterol functions as a muscarinic receptor and phospholipase C activator, enhancing the intracellular free calcium concentration in airway smooth muscle cells.</p>Formula:C13H21NO3Color and Shape:SolidMolecular weight:239.311NMDA receptor antagonist-3
<p>NMDA antagonist-3: recovery rate 40% at 100 μM, low toxicity in SH-SY5Y, human stem cells.</p>Formula:C13H19N3O6Color and Shape:SolidMolecular weight:313.31P-gp inhibitor 2
CAS:<p>Potent P-gp inhibitor 2 reverses Doxorubicin resistance in colorectal carcinoma cells with IC50 of 0.22 µM.</p>Formula:C29H26N2O6Color and Shape:SolidMolecular weight:498.53Lorajmine
CAS:Lorajmine, a monochloroacetyl derivative of ajmaline, is a class Ia antiarrhythmic agent that is rapidly hydrolyzed to ajmaline by plasma and tissue esterases.Formula:C22H27ClN2O3Purity:98%Color and Shape:SolidMolecular weight:402.91Dehydelone
CAS:<p>Dehydelone(KOS-1584, R-1645, SK-10088) is a microtubule stabilizer that may be used in the treatment of non-small cell lung cancer.</p>Formula:C27H39NO5SColor and Shape:SolidMolecular weight:489.67GABAA receptor agonist 2
<p>Compound 4c, a potent GABAA agonist with anti-depressive effects in mouse FST/TST, shows promise in depression research.</p>Formula:C22H36O5Color and Shape:SolidMolecular weight:380.52P-gp modulator 2
<p>P-gp modulator 2 (Compound 27) is a potent competitive and metabotropic P-glycoprotein (P-gp) modulator.</p>Formula:C22H20BrN3O4Color and Shape:SolidMolecular weight:470.32hURAT1 inhibitor 2
CAS:<p>hURAT1 inhibitor 2 (Compound 5) is an inhibitor of hURAT1 (uric acid transporter 1, SLC22A12) with an IC50 of 18 nM. It also exhibits some inhibitory activity against OATP1B1, with an IC50 of 0.73 μM. hURAT1 inhibitor 2 can be used in research related to hyperuricemia, gout, and other diseases associated with abnormal uric acid metabolism.</p>Formula:C17H11Br2FO3Color and Shape:SolidMolecular weight:442.074LY 215490
CAS:<p>LY 215490 is a selective AMPA receptor antagonist with neuroprotective properties in rat ischemia.</p>Formula:C13H21N5O2Purity:98%Color and Shape:SolidMolecular weight:279.34TRPC4/5-IN-1
<p>TRPC4/5-IN-1, a TRPC5/4 inhibitor with IC50s 0.54 μM/2.06 μM, targets skin inflammation and proteinuric kidney diseases.</p>Formula:C21H21N3OColor and Shape:SolidMolecular weight:331.41Probenecid sodium
CAS:<p>Probenecid sodium is the sodium salt of Probenecid, a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Additionally, Probenecid acts as an inhibitor of pannexin 1 channels.</p>Formula:C13H18NNaO4SColor and Shape:SolidMolecular weight:307.341(RS)-AMPA monohydrate
CAS:<p>(RS)-AMPA monohydrate, potent glutamate analogue, selectively activates L-glutamic acid without affecting kainic acid or NMDA receptors.</p>Formula:C7H12N2O5Color and Shape:SolidMolecular weight:204.1828-Prenylchrysin
CAS:<p>8-Prenylchrysin is a C8-isopentenyl flavonoid compound. It acts as an inhibitor of P-glycoprotein (P-gp) and can be utilized in cancer research.</p>Formula:C20H18O4Color and Shape:SolidMolecular weight:322.354INCB-056868
CAS:<p>INCB-056868 is the metabolite M11 of Epacadostat. It serves as a substrate for BCRP and holds potential for use in the study of metabolic diseases.</p>Formula:C11H13BrFN7O3SColor and Shape:SolidMolecular weight:422.23Unoprostone isopropyl
CAS:<p>Unoprostone isopropyl, a prostanoid and synthetic docosanoid, is approved for the treatment of ocular hypertension and open-angle glaucoma.</p>Formula:C25H44O5Purity:98%Color and Shape:SolidMolecular weight:424.61NSC73306
CAS:<p>NSC73306 is a thiosemicarbazone known for its role as a cell-permeable agent, exhibiting increased toxicity towards cells expressing p-glycoprotein.</p>Formula:C16H14N4O2SColor and Shape:SolidMolecular weight:326.373Lubeluzole dihydrochloride
CAS:<p>Lubeluzole (dihydrochloride) acts as a neuroprotective agent by blocking neuronal voltage-gated sodium channels and also affects cardiac sodium channels, exhibiting both tonic and blocking effects. This compound is considered promising in the research of antiarrhythmic agents.</p>Formula:C22H27Cl2F2N3O2SColor and Shape:SolidMolecular weight:506.44Kv7.2/Kv7.3 activator-1
CAS:<p>Kv7.2/Kv7.3 Activator-1 (compound 517) serves as a powerful activator of the Kv7.2/Kv7.3 channels, exhibiting an EC50 value of less than 1 µM. It holds potential for use in neurological disease research.</p>Formula:C19H22F2N4OColor and Shape:SolidMolecular weight:360.40PF-05661014
CAS:<p>PF-05661014, a demethylated analogue of PF-06526290, selectively inhibits Nav1.3 and Nav1.7 currents by stabilizing the inactivated state through interaction with the D4 VSD. This compound is utilized in research focused on sodium channel modulation.</p>Formula:C17H16N4O3S2Color and Shape:SolidMolecular weight:388.46CFTR corrector 16
CAS:<p>CFTRcorrector 16 (Compound 39) is a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR), utilized in the research of cystic fibrosis disease.</p>Formula:C27H26ClN5O2SColor and Shape:SolidMolecular weight:520.05SP100030 analogue 1
CAS:SP100030 analogue 1 (compound 11) is a selective transcription activation (SITA) inhibitor within the SP100030 class, capable of inhibiting XPO1-dependent upregulation of IL2 in a Jurkat-based IL2-Luc reporter assay, with an EC50 of 137 nM.Formula:C13H5ClF7N3OColor and Shape:SolidMolecular weight:387.64CFTR corrector 15
CAS:<p>CFTR Corrector 15 (Compound 4172) serves as a corrector for cystic fibrosis transmembrane conductance regulator (CFTR). When used in combination with VX-809, it addresses the folding defects of F508del-CFTR. CFTR Corrector 15 is also applicable in the research of cystic fibrosis.</p>Formula:C24H22ClN5O2SColor and Shape:SolidMolecular weight:479.98(2S,3S,11bR)-Dihydrotetrabenazine
CAS:<p>(2S,3S,11bR)-Dihydrotetrabenazine ((2S,3S,11bR)-DHTBZ) is a highly selective inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki value of 593 nM. It suppresses the vesicular transport of monoamine neurotransmitters, such as dopamine and serotonin, leading to reduced release into the synaptic cleft. This compound holds potential for research in Huntington's disease and other hyperkinetic movement disorders.</p>Formula:C19H29NO3Color and Shape:SolidMolecular weight:319.44DAD dichloride
<p>DAD dichloride is a 3rd-gen photoelectric switch, blocks K+ channels, and helps in visual function research.</p>Formula:C26H42Cl2N6OColor and Shape:SolidMolecular weight:525.56GABAA receptor agonist 1
<p>Compound 3e, a potent GABAA agonist, targets GABA sites and has potential anti-depressive effects in mice.</p>Formula:C20H30O3Color and Shape:SolidMolecular weight:318.45Odevixibat
CAS:<p>Odevixibat (A4250) is a selective oral inhibitor for ileal bile acid transport, potentially treating primary biliary cirrhosis.</p>Formula:C37H48N4O8S2Purity:99.53% - 99.83%Color and Shape:SolidMolecular weight:740.93SYM2206
CAS:<p>SYM2206 is a low affinity non-competitive AMPA receptor antagonist with an IC50 value of 1.6 μM.SYM2206 exhibits anticancer activity by blocking Nav1.6-mediated</p>Formula:C20H22N4O3Purity:99.88%Color and Shape:SolidMolecular weight:366.41SDZ 220-040
CAS:<p>SDZ 220-040 是一种选择性哺乳动物 NMDA 受体拮抗剂，可诱导根系生长的部分无重力模式 。</p>Formula:C16H16Cl2NO6PPurity:98.13%Color and Shape:SolidMolecular weight:420.18Suzetrigine
CAS:Suzetrigine (VX-548) is an oral NaV1.8 inhibitor with analgesic properties for acute pain research.Formula:C21H20F5N3O4Purity:98.08% - 99.27%Color and Shape:SolidMolecular weight:473.39(+)-Tetrabenazine
CAS:(+)-Tetrabenazine ((3R,11bR)-Tetrabenazine) is a reversible vesicular monoamine transporter 2 (VMAT-2) inhibitor, inhibits transport by VMAT2 with 10-foldFormula:C19H27NO3Purity:98.69%Color and Shape:SolidMolecular weight:317.42(-)-Bicuculline methobromide
CAS:<p>(-)-Bicuculline methobromide is a potent antagonist of GABAA receptor .</p>Formula:C21H20BrNO6Color and Shape:WhiteMolecular weight:462.29A-887826
CAS:A-887826 is a selective, orally bioavailable, and voltage-dependent Na(v1.8) channel blocker (IC50: 11 nM). It attenuates neuropathic tactile allodynia in vivo.Formula:C26H29ClN4O3Color and Shape:SolidMolecular weight:480.995-Hydroxylansoprazole
CAS:<p>5-Hydroxylansoprazole (AG1908) is the active metabolite of plasma Lansoprazole, inhibits the proton pump, and is used in the study of peptic ulcers.</p>Formula:C16H14F3N3O3SPurity:99.00%Color and Shape:SolidMolecular weight:385.36Umbellulone
CAS:Umbellulone is a natural product isolated from Umbellularia californica, and stimulates the TRPA1 channel in a subset of peptidergic, nociceptive neurons, activating the trigeminovascular system via this mechanism.Formula:C10H14OPurity:98%Color and Shape:SolidMolecular weight:150.22Indapamide
CAS:<p>Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.</p>Formula:C16H16ClN3O3SPurity:98.97% - 99.83%Color and Shape:SolidMolecular weight:365.832-AEMP TFA
CAS:<p>2-AEMP TFA is a potent and rapidly acting antagonist of GABA(A)-ρ1 receptors. 2-AEMP is an analog of GABA.</p>Formula:C3H10NO3PPurity:98%Color and Shape:SolidMolecular weight:139.091PF-06761281
CAS:<p>PF-06761281 is a partially selective sodium-coupled citrate transporter protein (NaCT/SLC13A5) inhibitor, oral, reducing plasma glucose concentration.</p>Formula:C13H17NO6Color and Shape:SolidMolecular weight:283.283-Methylglutaconic acid
CAS:<p>3-Methylglutaconic acid, a primary metabolite accumulating in 3-Methylglutaconic aciduria (MGTA), induces lipid and protein oxidation, while diminishing non-enzymatic antioxidant defenses in cerebral cortex supernatants, thereby promoting oxidative stress in the cerebral cortex. This compound is utilized in research concerning brain damage diseases [1].</p>Formula:C6H8O4Purity:98%Color and Shape:SolidMolecular weight:144.13Alfadolone acetate
CAS:<p>Alfadolone acetate is a gamma-aminobutyric acid (GABA) receptor agonist.</p>Formula:C23H34O5Color and Shape:SolidMolecular weight:390.51(Rac)-Lanicemine
CAS:<p>(Rac)-Lanicemine ((Rac)-AZD6765) is the racemate of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker with a Ki of 0.56-2.1 μM for the NMDA receptor and IC50 values of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively. Lanicemine shows antidepressant effects [1].</p>Formula:C13H14N2Color and Shape:SolidMolecular weight:198.26Verapamil EP Impurity C hydrochloride
CAS:<p>NSC-609249 hydrochloride, an impurity of Verapamil, is a calcium channel blocker with potent orally active properties. It also functions as a first-generation P-glycoprotein (P-gp) inhibitor.</p>Formula:C12H20ClNO2Color and Shape:SolidMolecular weight:245.75Apcin A HCL
CAS:<p>Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) inhibitor. Apcin-A HCL interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A HCL can be used to synthesize the PROTAC CP5V [1].</p>Formula:C10H15Cl4N5O2Purity:99.30%Color and Shape:SolidMolecular weight:379.07L-Cysteine S-sulfate sodium salt sesquihydrate
CAS:<p>L-Cysteine S-sulfate sodium salt sesquihydrate is a useful organic compound for research related to life sciences. The catalog number is T64782 and the CAS number is 150465-29-5.</p>Formula:C9H25N3Na3O17S6Color and Shape:SolidMolecular weight:708.63Zastaprazan
CAS:<p>Zastaprazan (JP-1366, compound 6) is a potassium-competitive acid blocker and proton pump inhibitor that suppresses gastric acid secretion, indicated for GERD.</p>Formula:C22H26N4OPurity:99.97%Color and Shape:SolidMolecular weight:362.48GNE-9278
CAS:<p>GNE-9278 is a highly selective NMDAR orthosteric modulator that targets the GluN1 transmembrane structural domain (TMD), enhancing peak current and agonist affinity in activated NMDAR.</p>Formula:C21H27N5O3SColor and Shape:SolidMolecular weight:429.54Indoxacarb
CAS:<p>Indoxacarb is an Oxadiazine insecticide.</p>Formula:C22H17ClF3N3O7Purity:98%Color and Shape:SolidMolecular weight:527.83Dexivacaine
CAS:Dexivacaine is an type of anesthetic.Formula:C15H22N2OColor and Shape:SolidMolecular weight:246.35(±)-Vasicine
CAS:<p>(±)-Vasicine, the racemate of Vasicine, is isolated from Peganum harmala seeds and exhibits anti-ulcer activity.</p>Formula:C11H12N2OPurity:98%Color and Shape:SolidMolecular weight:188.23Filapixant
CAS:<p>Filapixant, a purinoreceptor antagonist. This compound serves as the active reference substance for Eliapixant.</p>Formula:C24H26F3N5O3SColor and Shape:SolidMolecular weight:521.56Fostedil
CAS:Fostedil enhances heart function, maintains blood flow during partial/total coronary occlusions, and lowers aortic pressure.Formula:C18H20NO3PSPurity:98%Color and Shape:SolidMolecular weight:361.4Pazinaclone
CAS:<p>Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.</p>Formula:C25H23ClN4O4Purity:97.79% - 99.07%Color and Shape:SolidMolecular weight:478.93CGP 44532
CAS:<p>CGP 44532 a GABAB receptor agonist.</p>Formula:C4H12NO3PPurity:98%Color and Shape:SolidMolecular weight:153.12T16A(inh)-C01
CAS:<p>T16A(inh)-C01 is the Ca(2+)-activated Cl(-) Channel, Ano1 class C inhibitor.</p>Formula:C18H16O5Purity:98%Color and Shape:SolidMolecular weight:312.32Motugivatrep
CAS:<p>Motugivatrep is a potent and selective TRPV1 antagonist that can be used to study TRPV1-related respiratory diseases.</p>Formula:C22H20F3NO3Purity:99.22%Color and Shape:SolidMolecular weight:403.39Ref: TM-T64312
Discontinued productGacyclidine
CAS:<p>Gacyclidine (OTO311), an NMDA receptor blocker, treats tinnitus and injuries in the brain and spinal cord.</p>Formula:C16H25NSPurity:99.85% - 99.92%Color and Shape:SolidMolecular weight:263.44Phenamil methanesulfonate
CAS:<p>TRPP3 channel inhibitor</p>Formula:C13H16ClN7O4SPurity:98%Color and Shape:SolidMolecular weight:401.83Pipequaline
CAS:<p>Pipequaline (PK-8165) is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It possesses a novel chemical structure that is not closely related to other drugs of this type. The drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and very little sedative, amnestic or anticonvulsant effects, and so is classified as a nonbenzodiazepine anxiolytic.</p>Formula:C22H24N2Purity:98%Color and Shape:SolidMolecular weight:316.44Ref: TM-T4655
Discontinued productCMPDA
CAS:<p>CMPDA is a positive allosteric modulator of AMPA receptors [EC50s: 45.4 nM/63.4 nM for GluA2i/GluA2o receptor].</p>Formula:C16H28N2O4S2Purity:98%Color and Shape:SolidMolecular weight:376.53Tifenazoxide
CAS:<p>Tifenazoxide is an effective and SUR1/Kir6.2 selective KATP channels opener. Tifenazoxide has an anti-diabetic effect, can inhibit glucose-stimulated insulin release in vitro and in vivo.</p>Formula:C9H10ClN3O2S2Purity:98%Color and Shape:SolidMolecular weight:291.78HMR 1556
CAS:<p>HMR 1556 is a chromanol derivative and is an IKs blocker (IC50s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively).</p>Formula:C17H24F3NO5SColor and Shape:SolidMolecular weight:411.44CGP 56999A
CAS:CGP 56999A is a GABA(B) receptor antagonist; it boosts BDNF and reduces dopamine loss in rat striatum.Formula:C19H30NO5PPurity:98%Color and Shape:SolidMolecular weight:383.42Xilmenolone
CAS:<p>Xilmenolone acts as a positive allosteric modulator of the GABA_A receptor [1].</p>Formula:C26H37N3O2Purity:98%Color and Shape:SolidMolecular weight:423.59VMAT2-IN-2 tosylate
CAS:<p>VMAT2-IN-2 tosylate is a potent inhibitor of VMAT2 and is applicable in the research of tardive dyskinesia [1].</p>Formula:C27H36F3NO6SPurity:98%Color and Shape:SolidMolecular weight:559.64Bumetanide sodium
CAS:<p>Bumetanide sodium, a potent diuretic, blocks NKCC1 (IC50: 0.68 μM) and NKCC2 (IC50: 4.0 μM).</p>Formula:C17H19N2NaO5SColor and Shape:SolidMolecular weight:386.4LFS-1107
CAS:<p>LFS-1107, a reversible CRM1 inhibitor (Kd: 12.5 pM), selectively targets and eliminates ENKTL cells, offering potential for cancer research applications [1].</p>Formula:C12H11N5OS2Purity:98%Color and Shape:SolidMolecular weight:305.38Belfosdil
CAS:<p>Belfosdil is a blocker of antihypertensive calcium channel.</p>Formula:C27H50O7P2Purity:98%Color and Shape:SolidMolecular weight:548.63
