Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(93 products)
- Adiponectin receptor(5 products)
- CFTR(64 products)
- CGRP Receptor(51 products)
- Calcium Channel(493 products)
- Chloride channel(49 products)
- GABA Receptor(336 products)
- Monoamine Transporter(23 products)
- Monocarboxylate transporter(17 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(8 products)
- OAT(27 products)
- OCT(7 products)
- P-gp(53 products)
- Potassium Channel(276 products)
- Proton pump(39 products)
- SGLT(30 products)
- Sodium Channel(202 products)
- TRP/TRPV Channel(93 products)
Show 13 more subcategories
Found 2277 products of "Membrane Transporter/Ion Channel"
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PNU-140975
CAS:<p>PNU-140975 is a bio-active chemical.</p>Formula:C3H9N5O2Color and Shape:SolidMolecular weight:147.138Emamectin B1a
CAS:<p>Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.</p>Formula:C49H75NO13Color and Shape:SolidMolecular weight:886.133GDC-0334
CAS:<p>GDC-0334 is a TRPA1 antagonist useful in treatment TRPA1-mediated diseases, such as pain or asthma.</p>Formula:C24H19F8N5O3SColor and Shape:SolidMolecular weight:609.5Bendroflumethiazide
CAS:<p>Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)</p>Formula:C15H14F3N3O4S2Purity:98% - >99.99%Color and Shape:Crystals From Dioxane SolidMolecular weight:421.413-Aminopropylphosphonic Acid
CAS:<p>3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding</p>Formula:C3H10NO3PPurity:99.84%Color and Shape:Light Yellow LiquidMolecular weight:139.09Way 125971
CAS:<p>Way 125971 is a bioactive chemcial.</p>Formula:C22H28N4O5S2Color and Shape:SolidMolecular weight:492.61(R)-Funapide
CAS:<p>(R)-Funapide ((R)-TV 45070), the less active R-enantiomer of Funapide, acts as a potent Nav1.7 sodium channel blocker, primarily utilized in pain research [1].</p>Formula:C22H14F3NO5Color and Shape:SolidMolecular weight:429.35SLC6A8 corrector 1
<p>SLC6A8 Corrector 1 is an orally active corrector for mutant SLC6A8 variants, capable of crossing the blood-brain barrier. It is utilized in the study of creatine transporter deficiency (CTD).</p>Formula:C21H25N3O2Color and Shape:SolidMolecular weight:351.44GaTx2
CAS:<p>High-affinity ClC-2 blocker (KD ~50 pM), selective over other ClCs/CFTR/GABAC/CaCC/KV1.2; slows activation, no effect on open channels.</p>Formula:C125H199N39O47S6Purity:98%Color and Shape:SolidMolecular weight:3192.54Huwentoxin-IV
CAS:<p>Selective NaV1.7 blocker; also inhibits NaV1.2, 1.3; less effect on NaV1.4, 1.5. Binds to neurotoxin site, traps voltage sensor. IC50: 26-338 nM.</p>Formula:C174H278N52O51S6Purity:98%Color and Shape:SolidMolecular weight:4106.79Iberiotoxin
CAS:<p>Selective blocker of the big conductance Ca2+-activated K+ channel.</p>Formula:C179H274N50O55S7Purity:98%Color and Shape:SolidMolecular weight:4230OD1
<p>Activates rat Nav1.7, human Nav1.4, rat Nav1.6 (EC50: 7, 10, 47 nM); minimal on Nav1.2, 1.3, 1.5 (EC50 >3 μM); blocks fast inactivation; triggers pain.</p>Formula:C308H466N90O95S8Purity:98%Color and Shape:SolidMolecular weight:7206.1Idactamab
CAS:<p>Idactamab (INT-001) is a monoclonal antibody to the human amino acid transport protein ASCT2.</p>Purity:> 95%Color and Shape:LiquidMolecular weight:146.2 kDaAZD-3161
CAS:<p>AZD-3161 is a sodium channel regulator for pain.</p>Formula:C23H21F3N4O4Color and Shape:SolidMolecular weight:474.43GluN2B-NMDAR antagonist-1
<p>Orally active GluN2B-NMDAR antagonist with neuroprotective properties for ischemic injury research.</p>Formula:C26H23BrN2O2Color and Shape:SolidMolecular weight:475.38TRPV1 activator-1
CAS:<p>TRPV1 Activator-1 (Compound 8), a capsaicin analog featuring a modified neck structure, specifically interacts with the T551 residue [1].</p>Formula:C18H27NO2SColor and Shape:SolidMolecular weight:321.48MRS4596
<p>MRS4596: selective P2X4 blocker, IC50 1.38 μM, neuroprotective in stroke research.</p>Formula:C21H14N5NaO3SColor and Shape:SolidMolecular weight:439.42(R)-Lanicemine
CAS:<p>(R)-Lanicemine ((R)-AZD6765), an R-enantiomer with less activity, is a low-trapping NMDA blocker with antidepressant effects.</p>Formula:C13H14N2Color and Shape:SolidMolecular weight:198.26AChE/Aβ-IN-2
<p>AChE/Aβ-IN-2 (compound 33) is a powerful, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 135 nM.</p>Formula:C20H25ClN4Color and Shape:SolidMolecular weight:356.89Digoxigenin Monodigitoxoside
CAS:<p>Digoxigenin monodigitoxoside is a cardiac glycoside metabolite of digoxin and a Na+/K+ ATPase inhibitor.</p>Formula:C29H44O8Color and Shape:SolidMolecular weight:520.663NT 13
CAS:<p>NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.</p>Formula:C18H30N4O7Purity:98%Color and Shape:SolidMolecular weight:414.45sFTX-3.3
CAS:<p>sFTX-3.3 is a calcium ion channel antagonist, exhibiting IC50 values of approximately 0.24 mM and 0.70 mM against P-type and N-type channels respectively.</p>Formula:C12H29N7OColor and Shape:SolidMolecular weight:287.412PDZ1 Domain inhibitor peptide
CAS:<p>Novel cyclic peptide that disrupts interaction between GluR6 and PSD-95</p>Formula:C38H61N9O11Purity:98%Color and Shape:SolidMolecular weight:819.948-Bromo-ATP
CAS:<p>8-Bromo-ATP (8-Bromoadenosine 5'-triphosphate) is a purinergic P2X receptor agonist and an ATP analogue.</p>Formula:C10H15BrN5O13P3Color and Shape:SolidMolecular weight:586.077Nipecotic acid
CAS:<p>Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C6H11NO2Color and Shape:Off-White To Pale Yellow-Beige PowderMolecular weight:129.16JYL-79
CAS:<p>JYL-79 is an agonist of the vanilloid receptor.</p>Formula:C26H36N2O4SColor and Shape:SolidMolecular weight:472.64P-gp inhibitor 13
<p>P-gp Inhibitor 13, a P-glycoprotein antagonist, can counteract paclitaxel resistance in A2780/T cells, proving valuable for advanced acute myeloid leukemia</p>Formula:C32H34O8Color and Shape:SolidMolecular weight:546.61CHET3
CAS:<p>CHET3 is a highly selective allosteric activator for TASK-3-containing K2P channels. CHET3 has shown potent in vivo analgesic effects. Cost-effective and quality-assured.</p>Formula:C21H21N5O3SPurity:99.64% - >99.99%Color and Shape:SoildMolecular weight:423.49Lyso-Globotriaosylceramide (d18:1)
CAS:<p>Lyso-Gb3, lacking fatty acyl, binds Stx1 with cholesterol and phosphatidylcholine, not Stx2; lowers neutrophil viability; accumulates in Fabry disease.</p>Formula:C36H67NO17Color and Shape:SolidMolecular weight:785.922Anticancer agent 108
<p>Anticancer Agent 108 (Compound 3.10) serves as a potent P-gp inhibitor exhibiting considerable antitumor properties while maintaining reduced toxicity to both</p>Formula:C18H9NO5S2Color and Shape:SolidMolecular weight:383.4ADWX 1
<p>Potent KV1.3 blocker, IC50: 0.0019 nM; less effective on KV1.1. Curbs CD4+ T cell activation; eases rat multiple sclerosis model.</p>Formula:C169H281N57O46S7Purity:98%Color and Shape:SolidMolecular weight:4071.86Mesoridazine free base
CAS:<p>Mesoridazine (thioridazine EP impurity B) is a phenothiazine antipsychotic with effects similar to chlorpromazine.</p>Formula:C21H26N2OS2Color and Shape:SolidMolecular weight:386.57Neurotransmitter Receptor Compound Library
<p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；</p>Color and Shape:Odour SolidGpTx-1 TFA
<p>GpTx-1 TFA is a polypeptide NaV1.7 sodium channel antagonist isolated from the venom of the Chilean spider Grammostola porter. It exhibits potent inhibitory activity on the NaV1.7 channel with an IC50 value of 10 nM, demonstrating excellent selectivity over NaV1.4 (IC50 = 0.301 μM) and NaV1.5 (IC50 = 4.20 μM) with >20-fold and >950-fold selectivity, respectively.</p>Color and Shape:Odour SolidD-GsMTx4
<p>TRPC1/6 & Piezo2 inhibitor; mimics GsMTx4; blocks ~70% mechanosensitive currents; aids in mouse heart attack models; protease-resistant.</p>Color and Shape:SoildAQP3-IN-1
CAS:<p>AQP3-IN-1 (compounds 3), an AQP3 inhibitor, exhibits an IC 50 of 8.91 μM and effectively inhibits melanoma cell proliferation [1].</p>Formula:C11H9AuCl2N2Color and Shape:SolidMolecular weight:437.08CPI1
<p>CPI1 is an effective and highly specific inhibitor of multidrug resistance protein 1 (MRP1). It exhibits inhibitory activity against MRP1 at the nanomolar level (Ki: 100 nM) and has minimal effect on P-glycoprotein (Pgp). CPI1 competes with LTC4 for binding to the same site on MRP1, inhibiting ATP hydrolysis and substrate transport. It is useful in research related to drug delivery and addressing cancer chemotherapy resistance.</p>Formula:C111H131N23O30SColor and Shape:SolidMolecular weight:2299.43Dendrotoxin K
CAS:<p>Dendrotoxin K blocks Kv1.1 channels, modulating glutamate release in CA3 neurons by controlling presynaptic spike timing.</p>Formula:C294H462N84O75S6Color and Shape:SolidMolecular weight:6559.66Mutabilol
<p>Mutabilol boosts P-gp in NCI-H460/R cells; natural from Plectranthus mutabilis.</p>Formula:C19H24O5Color and Shape:SolidMolecular weight:332.39Ethacrynic acid D5
CAS:<p>Ethacrynic acid: a diuretic, anti-inflammatory, inhibits calcium channels, GSTs, NF-kB pathway, and modulates leukotriene; has deuterium-labeled form.</p>Formula:C13H12Cl2O4Purity:98%Color and Shape:SolidMolecular weight:308.17(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS:<p>(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.</p>Formula:C6H11NO2Color and Shape:SolidMolecular weight:129.16CP-628006
CAS:<p>CP-628006 is a small molecule CFTR potentiator that effectively restores ATP-dependent channel gating to G551D-CFTR, the mutant form found in cystic fibrosis.</p>Formula:C32H35F3N2O2Color and Shape:SolidMolecular weight:536.639Atelopidtoxin
CAS:<p>Atelopidtoxin is a biochemical.</p>Formula:C16H24N8O12SColor and Shape:SolidMolecular weight:552.47(±)8(9)-EpETE
CAS:<p>(±)8(9)-EpETE ((±)8,9-EEQ) is an epoxide of arachidonic acid biosynthesized by CYP450 epoxygenase.1.2 In rat and rabbit liver microsomes.</p>Formula:C20H30O3Color and Shape:SolidMolecular weight:318.45Crocetin meglumine
<p>Crocetin (Transcrocetin) meglumine, sourced from Crocus sativus L. (saffron), functions as a high-affinity antagonist of the NMDA receptor.</p>Formula:C34H58N2O14Color and Shape:SolidMolecular weight:718.83Jingzhaotoxin-XII TFA
<p>Jingzhaotoxin-XII (JzTx-XII) TFA is a specific inhibitor of the Kv4.1 channel, exhibiting an IC50 of 0.363 μM. It interacts with the channel by altering gating behavior.</p>Color and Shape:Odour SolidBrevetoxin-3
CAS:<p>Brevetoxin-3 activates Na+ channels, binding strongly to site 5, preventing their inactivation.</p>Formula:C50H72O14Purity:98%Color and Shape:SolidMolecular weight:897.112Nitrazolam
CAS:<p>Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.</p>Formula:C17H13N5O2Color and Shape:SolidMolecular weight:319.32Phrixotoxin 3
CAS:<p>Potent NaV blocker: IC50 - 0.6 nM (NaV1.2), 42 nM (NaV1.3), 72 nM (NaV1.5); voltage-dependent inhibition.</p>Formula:C176H269N51O48S6Purity:98%Color and Shape:SolidMolecular weight:4059.74Transdermal Peptide Disulfide
CAS:<p>TD 1 peptide, an 11-amino acid, binds ATP1B1's C-terminus, enhancing transdermal drug delivery.</p>Formula:C40H64N14O16S2Purity:98%Color and Shape:SolidMolecular weight:1061.15Tiludronate disodium hemihydrate
CAS:<p>Tiludronate: an oral bisphosphonate for bone disorder research; inhibits osteoclasts and reduces inflammation.</p>Formula:C14H16Cl2Na4O13P4S2Color and Shape:SolidMolecular weight:743.164'-hydroxy Trazodone
CAS:<p>4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone.1It is an inhibitor of organic anion transporter 3 (OAT3; Ki= 16.9 μM) and is</p>Formula:C19H22ClN5O2Color and Shape:SolidMolecular weight:387.87ω-Agatoxin TK
CAS:<p>Selective blocker of CaV2.1 P/Q-type calcium channels.</p>Formula:C215H337N65O70S10Purity:98%Color and Shape:SolidMolecular weight:5273.02AVLX-125
CAS:<p>AVLX-125 (UCCB01-125), a potent inhibitor of PSD-95 and PDZ domains, exhibits a dissociation constant (Kd) of 10 nM. It is utilized in researching inflammatory pain [1] [2].</p>Formula:C62H104N10O29Color and Shape:SolidMolecular weight:1453.54TRPV4 antagonist 3
CAS:<p>TRPV4 antagonist 3 is a TRPV4 antagonist (p IC 50 = 8.4).</p>Formula:C20H18F4N4O3SColor and Shape:SolidMolecular weight:470.44Phe-Met-Arg-Phe, amide
CAS:<p>Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.</p>Formula:C29H42N8O4SPurity:98%Color and Shape:SolidMolecular weight:598.76LTGO-33
CAS:<p>LTGO-33 is a voltage-gated sodium channel NaV1.8 inhibitor that inhibits NaV1.8, NaV1.1-NaV1.7, and NaV1.9.</p>Formula:C21H17F4N3O3SPurity:97.6%Color and Shape:SoildMolecular weight:467.44Tariquidar dimesylate
CAS:<p>Tariquidar, a non-competitive P-glycoprotein inhibitor, may help combat cancer drug resistance.</p>Formula:C80H94N8O25S4Purity:98%Color and Shape:SolidMolecular weight:1695.9epi-Aszonalenin A
CAS:<p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>Formula:C25H25N3O3Color and Shape:SolidMolecular weight:415.48LY-368975 hydrochloride
CAS:<p>LY-368975 hydrochloride is a bioactive chemical.</p>Formula:C17H22ClNOSColor and Shape:SolidMolecular weight:323.88NAADP tetrasodium salt
CAS:<p>Ca2+ mobilizing agent</p>Formula:C21H27N6O18P3Purity:98%Color and Shape:SolidMolecular weight:744.39Imagabalin
CAS:<p>Imagabalin is an active compound used in the study of neurological diseases.</p>Formula:C9H19NO2Color and Shape:SolidMolecular weight:173.25Chlorotoxin(linear)
<p>Chlorotoxin(linear): 36-amino-acid peptide from Egyptian scorpion venom, used in research as chloride channel blocker.</p>Formula:C158H256N52O48S11Purity:98%Color and Shape:SolidMolecular weight:4004.76TRPV1 activator-2
CAS:<p>TRPV1 activator-2 (Compound 9), a capsaicin head analog, engages in targeted interactions with channel residues at the lipid-water interface [1].</p>Formula:C19H29NO3Color and Shape:SolidMolecular weight:319.44PtdIns-(1,2-dioctanoyl) (sodium salt)
CAS:<p>PtdIns phosphates, a minor membrane lipid fraction, are vital for cell signaling. Synthetic PtdIns-(1,2-dioctanoyl) has C8:0 fatty acids and high solubility.</p>Formula:C25H47NaO13PColor and Shape:SolidMolecular weight:609.602P-gp inhibitor 27
<p>P-gp inhibitor 27 (Compound D2) is an inhibitor of P-glycoprotein (P-gp) that reduces the expression of P-gp and MRP1. It increases the accumulation of Rh123 in A2780/T cells and reverses multidrug resistance to Paclitaxel (EC50 of 88 nM) and Cisplatin.</p>Formula:C25H25N3O4Color and Shape:SolidMolecular weight:431.48Withasomniferolide B
CAS:<p>Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.</p>Formula:C28H36O4Color and Shape:SolidMolecular weight:436.5817R(18S)-EpETE
CAS:<p>17R(18S)-EpETE: Oxylipin, eicosapentaenoic acid metabolite, activates BKCa channels, has negative chronotropic effects.</p>Formula:C20H30O3Color and Shape:SolidMolecular weight:318.457Conantokin G TFA
<p>Conantokin G TFA, a 17-aa peptide, blocks NMDA receptors with 480 nM IC50 and is neuroprotective.</p>Formula:C90H139F3N26O46Color and Shape:SolidMolecular weight:2378.21Vanzacaftor
CAS:<p>Vanzacaftor is a CFTR modulator improving protein processing and surface trafficking, restoring chloride transport and aiding cystic fibrosis therapy research.</p>Formula:C32H39N7O4SPurity:99.14%Color and Shape:SolidMolecular weight:617.76Idrevloride
CAS:<p>Idrevloride (WO2016133967) inhibits ENaC, used in skin disorder research.</p>Formula:C30H49ClN8O7Color and Shape:SolidMolecular weight:669.22ML353
<p>ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.</p>Formula:C19H15FN2OPurity:99.98% - 99.98%Color and Shape:SoildMolecular weight:306.33(S)-JNJ-54166060
CAS:<p>(S)-JNJ-54166060, an enantiomer of JNJ-54166060, functions as a potent antagonist of P2X7 [1].</p>Formula:C20H15ClF4N4OColor and Shape:SolidMolecular weight:438.81Tenapanor HCl
CAS:<p>Tenapanor (AZD-1722, RDX 5791) inhibits NHE3 for sodium control in the gut and kidneys.</p>Formula:C50H68Cl6N8O10S2Color and Shape:SolidMolecular weight:1217.97BDBM50597431
CAS:<p>BDBM50597431 is an NMDA receptor modulator that may have can be used to study Alzheimer's disease and Parkinson's syndrome.</p>Formula:C27H43F3O2Purity:98.64% - 99.28%Color and Shape:SoildMolecular weight:456.62Homocarnosine TFA
<p>Homocarnosine TFA: brain-exclusive GABA-histidine dipeptide, neuronal, anticonvulsant, antioxidant, anti-inflammatory.</p>Formula:C12H17F3N4O5Color and Shape:SolidMolecular weight:354.28Tertiapin LQ
<p>Kir1.1 channel blocker, 250x selective; Kd: Kir1.1 (1.1 nM), Kir3.1/3.2 (274 nM), Kir3.1/3.4 (361 nM). Tertiapin-Q derivative.</p>Formula:C106H179N33O24S4Purity:98%Color and Shape:SolidMolecular weight:2428.03D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)
CAS:<p>Ins(1,3,4,5)-P4, made via Ins(1,4,5)P3 phosphorylation, boosts calcium by opening ER and plasma membrane channels.</p>Formula:C6H8Na8O18P4Color and Shape:SolidMolecular weight:675.93Antidepressant agent 4
<p>Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.</p>Formula:C19H38ClN5O2SColor and Shape:SolidMolecular weight:436.06(±)5(6)-DiHETE
CAS:<p>Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.</p>Formula:C20H32O4Color and Shape:SolidMolecular weight:336.47218β-Glycyrrhetyl-3-O-sulfate
CAS:<p>18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2</p>Formula:C30H46O7SColor and Shape:SolidMolecular weight:550.75MIDD0301
CAS:<p>MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.</p>Formula:C19H13BrFN3O2Purity:98%Color and Shape:SolidMolecular weight:414.23Jingzhaotoxin III
CAS:<p>NaV1.5 channels blocker</p>Formula:C174H241N47O46S6Purity:98%Color and Shape:SolidMolecular weight:3919.47Withaphysalin D
CAS:<p>Withaphysalin D, from water lilies, blocks GluN2B NMDARs and is neuroprotective, crossing the blood-brain barrier.</p>Formula:C28H34O6Color and Shape:SolidMolecular weight:466.57Lifarizine FA
<p>Lifarizine FA is a sodium channel blocker used in the treatment of neurological disorders and cardiovascular diseases, study of stroke.</p>Formula:C30H34N4O2Purity:99.55%Color and Shape:SolidMolecular weight:482.6224-Hydroxycholesterol
CAS:<p>24-Hydroxycholesterol (Cholest-5-ene-3beta,24-diol) is an activator of the LXR and can be used to study cardiogenesis and pancreatic cancer.</p>Formula:C27H46O2Purity:99.8%Color and Shape:SolidMolecular weight:402.656,7-dimethylisatin
CAS:<p>6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.</p>Formula:C10H9NO2Purity:98.98%Color and Shape:SolidMolecular weight:175.18(R)-IDHP
CAS:<p>(R)-IDHP, a salvia derivative, relaxes blood vessels by blocking calcium channels, aiding cardiovascular research.</p>Formula:C12H16O5Color and Shape:SolidMolecular weight:240.25Sinapine hydroxide
CAS:<p>Sinapine hydroxide from crucifer seeds has anti-inflammatory, anti-oxidant, anti-tumor properties, and inhibits AChE, aiding neurodegenerative research.</p>Formula:C16H25NO6Color and Shape:SolidMolecular weight:327.377Volixibat
CAS:<p>Volixibat, a selective inhibitor of the bile acid transporter, may treat non-alcoholic steatohepatitis.</p>Formula:C38H51N3O12S2Purity:98%Color and Shape:SolidMolecular weight:805.95(±)16-HETE
CAS:<p>Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.</p>Formula:C20H32O3Color and Shape:SolidMolecular weight:320.473L-Ibotenic acid
CAS:<p>L-Ibotenic acid: a psychoactive found in Amanita mushrooms, mimics glutamate, activates receptors.</p>Formula:C5H6N2O4Color and Shape:SolidMolecular weight:158.11AChE/Aβ-IN-1
<p>AChE/Aβ-IN-1 (compound 32) is a potent, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 86 nM and an NMDA receptor antagonist targeting the</p>Formula:C20H25BrN4Color and Shape:SolidMolecular weight:401.34LU-32-176B
CAS:<p>LU32-176B is a bioactive chemical.</p>Formula:C23H24F2N2O2Color and Shape:SolidMolecular weight:398.45Conantokin-R
CAS:<p>Conantokin-R is an NMDA receptor peptide antagonist (IC50=93 nM); Conantokin-R exhibits anticonvulsant activity; Conantokin-R binds Zn2+ and Mg2+ (Kds 0.15 μM</p>Formula:C127H201N35O49S3Color and Shape:SolidMolecular weight:3098.38Elgodipine
CAS:<p>Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.</p>Formula:C29H33FN2O6Purity:98.95% - 99.50%Color and Shape:SolidMolecular weight:524.58BMS 199264
CAS:<p>BMS 199264 hydrochlorid a inhibitor of mitochondrial F1F0 ATP hydrolase, thus preventing ATP reduction to ameliorate cardiac necrosis during ischemia.</p>Formula:C26H31ClN4O4SPurity:99.83%Color and Shape:SoildMolecular weight:531.07S-WJM992
<p>S-WJM992 (compound 10ahb) serves as an antiparasitic agent, effectively inhibiting ATPase activity in high [Na+] environments. It also significantly counteracts parasites resistant to PfATP4 inhibitors. Additionally, S-WJM992 acts as a potential transmission blocker by impeding gamete development and halting the transmission of parasites to mosquitoes during blood feeding.</p>Formula:C22H18ClFN6O3Color and Shape:SolidMolecular weight:468.87KCC2 potentiators-1
CAS:<p>Compound 2, known as KCC2 potentiators-1, acts as an enhancer of the potassium chloride cotransporter-2 (KCC2). It holds potential for applications in studies related to neurological disorders.</p>Formula:C15H17N3OSColor and Shape:SolidMolecular weight:287.38Carbonic anhydrase inhibitor 32
<p>Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.</p>Formula:C17H16N6O3SColor and Shape:SolidMolecular weight:384.41α-Casozepine
CAS:<p>α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.</p>Formula:C60H94N14O16Color and Shape:SolidMolecular weight:1267.47Ruzinurad
CAS:<p>Ruzinurad (WO2020088641, compound I) is a potent URAT1 inhibitor, exhibiting high selectivity.</p>Formula:C14H12BrNO2SColor and Shape:SolidMolecular weight:338.22AR-C141990 hydrochloride
CAS:<p>AR-C141990 HCl inhibits MCT-1 (pKi 7.6) and MCT-2 (pKi 6.6), and has immunosuppressive effects.</p>Formula:C26H29ClN4O4SColor and Shape:SolidMolecular weight:529.05Venturicidin A
CAS:<p>Venturicidin A is a macrolide antibiotic.</p>Formula:C41H67NO11Purity:98%Color and Shape:SolidMolecular weight:749.97P-gp/BCRP-IN-2
<p>P-gp/BCRP-IN-2 (compound 15), an oxadiazole derivative, functions as a dual inhibitor targeting both the ABC transporter P-glycoprotein (IC50: 1.6 nM) and BCRP</p>Formula:C32H35N3O6Color and Shape:SolidMolecular weight:557.64Chlorpropylate
CAS:<p>Chlorpropylate is an insecticide.</p>Formula:C17H16Cl2O3Purity:98%Color and Shape:SolidMolecular weight:339.21URAT1 inhibitor 11
CAS:<p>URAT1 inhibitor11 (Compound 7) is a potent URAT1 inhibitor, exhibiting an IC50 of 0.18 μM. It effectively reduces uric acid levels in zebrafish with hyperuricemia induced by Potassium oxonate and Xanthinesodium salt.</p>Formula:C20H16F4N2O2Color and Shape:SolidMolecular weight:392.35Camegliptin
CAS:<p>Cameglipti, a dipeptidyl peptidase IV (DPP-4) inhibitor, is used potentially for the treatment of type 2 diabetes.</p>Formula:C20H28FN3O3Color and Shape:SolidMolecular weight:377.45FD 12-9
CAS:<p>FD 12-9, Anti-glioblastoma activity. is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively.</p>Formula:C51H47N3O11Purity:98%Color and Shape:SolidMolecular weight:877.93Aglafoline
CAS:<p>Aglafoline inhibits in a concentration-dependent manner the aggregation and ATP release reaction induced in washed rabbit platelets by PAF (platelet-activating</p>Formula:C28H28O8Color and Shape:SolidMolecular weight:492.52TRPA1 Antagonist 3
CAS:<p>TRPA1 Antagonist 3 is a compound with photoswitchable properties that acts as an agonist on the TRPA1 channel, providing the ability for optical control.</p>Formula:C11H8ClN3Color and Shape:SolidMolecular weight:217.66Cyclocreatine
CAS:<p>Cyclocreatine, a creatine analogue and substrate for creatine kinase, inhibits creatine metabolism and prostate cancer cell proliferation.</p>Formula:C5H9N3O2Purity:99.864%Color and Shape:SolidMolecular weight:143.144-Hydroxytolbutamide
CAS:<p>4-Hydroxytolbutamide is a drug metabolite derived from the metabolism of Tolbutamide by CYP2C8 and CYP2C9 a sulfonylurea hypoglycemic agent.</p>Formula:C12H18N2O4SPurity:98%Color and Shape:White To Off-WhiteMolecular weight:286.35Bafilomycin B1
CAS:<p>Bafilomycin B1, a Streptomyces-derived macrolide, inhibits E. coli ATPase and fights Gram-positive bacteria and fungi.</p>Formula:C44H65NO13Purity:98%Color and Shape:White PowderMolecular weight:815.998Antimalarial agent 41
<p>Antimalarial agent 41 (Compound 17) exhibits antimalarial activity by inhibiting the malaria parasite Plasmodium falciparum, with IC50 values of 40 nM for NF54 strain and 76 nM for K1 strain. This compound acts as an inhibitor of P. falciparum phosphatidylinositol-4-kinase β (PfPI4K) and hERG channels, with IC50 values of 53 nM and 3 μM, respectively. Additionally, Antimalarial agent 41 shows cytotoxicity against CHO cells, with an IC50 of 34 μM. It can improve malaria infections and demonstrates favorable pharmacokinetic properties in mouse models.</p>Formula:C19H18F3N5Molecular weight:373.15143UK-59811 hydrochloride
CAS:<p>UK-59811 hydrochloride, Br-dihydropyridine derivative, blocks Ca V Ab channels in bacteria, IC50: 194 nM.</p>Formula:C22H30BrClN2O5Color and Shape:SolidMolecular weight:517.85Conantokin-T
CAS:<p>Non-competitive NMDA receptor antagonist</p>Formula:C110H175N31O45SPurity:98%Color and Shape:SolidMolecular weight:2683.81Homocarnosine
CAS:<p>Homocarnosine is an endogenous dipeptide in cerebral regions and cerebrospinal fluid.</p>Formula:C10H16N4O3Color and Shape:SolidMolecular weight:240.26APETx2 TFA
<p>APETx2 TFA from sea anemone is a selective ASIC3 inhibitor with a 63 nM IC50, reversing acid and inflammatory pain.</p>Formula:C198H281F3N54O62S6Color and Shape:SolidMolecular weight:4675.02CALP3
CAS:<p>Cell-permeable CaM agonist, binds EF-hand, activates phosphodiesterase without Ca2+, inhibits Ca2+ toxicity, IC50=33μM.</p>Formula:C44H68N10O9Purity:98%Color and Shape:SolidMolecular weight:881.08(S)-PF-03716556
CAS:<p>(S)-PF-03716556 can be used as an acid pump inhibitor for the treatment of disease conditions mediated by acid pump inhibitory activity.</p>Formula:C22H26N4O3Purity:99.8% - 99.91%Color and Shape:SoildMolecular weight:394.47ω-Conotoxin MVIIC
CAS:<p>Peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.</p>Formula:C106H178N40O32S7Purity:98%Color and Shape:White Lyophilised SolidMolecular weight:2749ω-Conotoxin MVIIC TFA
<p>ω-Conotoxin MVIIC TFA is a peptide and neurotoxin blocks P-type and q-type voltage-sensitive neuronal Ca ++ channels (VGCCs) radiolabel immunoprecipitation.</p>Formula:C106H178N40O32S7·C2HF3O2Color and Shape:SolidMolecular weight:2863.27Isotachysterol 3
CAS:<p>Isotachysterol 3 boosts calcium transport in gut and bone mobilization in kidneyless rats.</p>Formula:C27H44OColor and Shape:SolidMolecular weight:384.64Guangxitoxin 1E
CAS:<p>Guangxitoxin 1E acts as a gating modifier since it shifts the voltage-dependence of Kv2.1 K+ currents towards depolarized potentials.</p>Formula:C178H248N44O45S7Purity:98%Color and Shape:SolidMolecular weight:3948.61AP14145 hydrochloride
CAS:<p>AP14145 hydrochloride inhibits KCa2.2 and KCa2.3 channels with 1.1 μM IC50, affecting AERP and antiarrhythmic in AF models.</p>Formula:C18H18ClF3N4OColor and Shape:SolidMolecular weight:398.816-FAM-AEEAC-SHK TFA
<p>6-FAM-AEEAC-SHK TFA, a peptide neurotoxin derived from Stichodactyla helianthus and conjugated with a fluorescent marker, selectively blocks voltage-gated potassium channels (kv1.1 and kv1.2). By prolonging action potentials, it interferes with neural signal conduction, making it valuable in neuroscience research.</p>Formula:C196H295N55O57S7·xCHF3O2Color and Shape:SolidMolecular weight:4558.23 (free acid)17(S)-HETE
CAS:<p>Arachidonic acid and its CYP450 metabolite, 17(S)-HETE, regulate kidney electrolytes; 17(S)-HETE reduces proximal tubule ATPase activity by 70% at 2 μM.</p>Formula:C20H32O3Color and Shape:SolidMolecular weight:320.473Detajmium bitartrate
CAS:<p>Detajmium bitartrate is used as an antiarrhythmic drug.</p>Formula:C31H47N3O9Color and Shape:SolidMolecular weight:605.72Huwentoxin I
CAS:<p>Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.</p>Formula:C161H246N48O44S6Purity:98%Color and Shape:SolidMolecular weight:3750.36Trans (2,3)-Dihydrotetrabenazine
CAS:<p>Trans (2,3)-Dihydrotetrabenazine is a Tetrabenazine metabolite, shows inhibition activity on vesicular monoamine transporter (VMAT2).</p>Formula:C19H29NO3Purity:98%Color and Shape:SolidMolecular weight:319.44TP-050
CAS:<p>TP-050: potent, selective NMDAR agonist, EC50 0.51 µM (GluN2A), 9.6 µM (GluN2D), BBB permeable, boosts hippocampal LTP.</p>Formula:C16H15ClF2N6OColor and Shape:SolidMolecular weight:380.78(R)-AMPA
CAS:<p>inactive enantiomer of AMPA</p>Formula:C7H10N2O4Purity:98%Color and Shape:SolidMolecular weight:186.17BeKm-1
CAS:<p>Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.</p>Formula:C174H261N51O52S6Purity:98%Color and Shape:SolidMolecular weight:4091.65NSC799462
<p>NSC799462, a triazole inhibitor, specifically targets p97 ATPase, exerting its effect by binding to a designated site on the p97 enzyme. This interaction induces localized structural alterations in p97, effectively inhibiting its ATPase activity with an IC 50 value of 15 nM.</p>Formula:C30H32F2N6O3SColor and Shape:SolidMolecular weight:594.68NF110
CAS:<p>P2X3 antagonist</p>Formula:C41H32N6NaO17S4Purity:98%Color and Shape:SolidMolecular weight:1031.97N-hydroxy Riluzole
CAS:<p>N-hydroxy Riluzole, a metabolite of riluzole, is mainly produced by CYP1A2 in human liver.</p>Formula:C8H5F3N2O2SColor and Shape:SolidMolecular weight:250.20Cavα2δ-IN-1
CAS:<p>Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a Ki</p>Formula:C18H27N5OColor and Shape:SolidMolecular weight:329.448Sulcardine 2HCl
CAS:<p>Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.</p>Formula:C24H35Cl2N3O4SPurity:99.33% - 99.76%Color and Shape:SoildMolecular weight:532.523EVT-401
<p>EVT-401 (P2X7 receptor antagonist-1), a purinergic P2X7 receptor antagonist, demonstrates efficacy in combating neuroinflammation [1].</p>Formula:C22H20F4N2O3Color and Shape:SolidMolecular weight:436.4ω-Conotoxin GVIA
CAS:<p>Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.</p>Formula:C120H182N38O43S6Purity:98%Color and Shape:SolidMolecular weight:3037A-317567
CAS:A-317567 is a potent acid-sensing ion channel 3 (ASIC-3) inhibitor with an IC50 of 1.025 μM, and it has antidepressant and antinociception effects[1][2].Formula:C27H31N3Purity:98%Color and Shape:SolidMolecular weight:397.56Cevadine
<p>Cevadine is a natural product that can be used as a reference standard.</p>Formula:C32H49NO9Color and Shape:SolidMolecular weight:591.742GsMTx4
CAS:<p>GsMTx-4, mechanosensitive and stretch-activated ion channel inhibitor (CAS 1209500-46-8).</p>Formula:C185H273N49O45S6Purity:98%Color and Shape:SolidMolecular weight:4095.84Resolvin D2
CAS:<p>Resolvin D2 (RvD2) is a TRPV1 inhibitor and pro-ablative mediator with anti-inflammatory, anti-infective and pro-ablative effects.</p>Formula:C22H32O5Purity:98%Color and Shape:SolidMolecular weight:376.49Caloxin 2A1 acetate
<p>Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide.</p>Formula:C66H95N19O24Purity:98.2%Color and Shape:SolidMolecular weight:1538.5712,14-Dichlorodehydroabietic acid
CAS:<p>12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.</p>Formula:C20H26Cl2O2Color and Shape:SolidMolecular weight:369.33Halazone
CAS:<p>Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.</p>Formula:C7H5Cl2NO4SPurity:98.64%Color and Shape:Physical Description Fine White Powder With An Odor Of Chlorine (Ntp 1992)Molecular weight:270.09CW2158
<p>CW2158 (Compound 13) is a modulator of exportin1 (XPO1). It disrupts chromatin binding and inhibits the activation of NFAT transcription factors and T cells.</p>Formula:C14H8F4N4O2Molecular weight:340.05834Eltanexor
CAS:<p>Eltanexor, an oral XPO1 inhibitor, induces apoptosis in leukemia cells; EC50=60.9 nM.</p>Formula:C17H10F6N6OPurity:99.6% - ≥98%Color and Shape:SolidMolecular weight:428.29AmmTX3
<p>KV4 channel blocker that inhibits A-type K+ current in mouse neurons; requires DPP6 and DPP10 for effect.</p>Formula:C158H262N50O48S6Purity:98%Color and Shape:SolidMolecular weight:3822.47Verruculogen
CAS:<p>Verruculogen, a toxin from Penicillium/Aspergillus, blocks Ca2+-K+ channels and halts mammalian M phase.</p>Formula:C27H33N3O7Purity:98%Color and Shape:White PowderMolecular weight:511.57Furosemide sodium
CAS:<p>Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.</p>Formula:C12H10ClN2NaO5SPurity:99.52% - >99.99%Color and Shape:SolidMolecular weight:352.73GS-9191 PM
<p>GS-9191 PM: novel antitumorviral bis-amide prodrug, inhibits MDR1/BCRP, has antiproliferative activity.</p>Formula:C11H16N6OPurity:99.79%Color and Shape:SoildMolecular weight:248.28SLC26A3-IN-2
CAS:<p>Vilobelimab (CaCP-29) is a human-mouse chimeric IgG antibody targeting human complement component 5a, a C5a inhibitor that inhibits neutrophil activation.</p>Formula:C19H13ClN2O2SPurity:99.86%Color and Shape:SolidMolecular weight:368.84SNX-482
CAS:<p>Potent CaV2.3 calcium channel blocker, selective, voltage-dependent, with 30 nM IC50. Offers antinociceptive effects on C and Aδ fibres.</p>Formula:C192H274N52O60S7Purity:98%Color and Shape:SolidMolecular weight:4495.01TRPA1-IN-2
CAS:<p>TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM.TRPA1-IN-2 has anti-inflammatory activity.</p>Formula:C24H25F3N4OPurity:98.05%Color and Shape:SoildMolecular weight:442.48NSC156529
CAS:<p>NSC156529 suppresses AKT1, reduces cancer cell growth in vitro, and inhibits prostate tumors in vivo.</p>Formula:C28H21ClS2Purity:98%Color and Shape:SolidMolecular weight:457.05Apamin
CAS:<p>Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.</p>Formula:C79H131N31O24S4Purity:98%Color and Shape:SolidMolecular weight:2027.34(Rac)-Tezacaftor
CAS:<p>(Rac)-Tezacaftor, a racemate, corrects F508del CFTR for cystic fibrosis research.</p>Formula:C26H27F3N2O6Color and Shape:SolidMolecular weight:520.5c-Met-IN-23
<p>c-Met-IN-23 (Compound 12g) functions as a c-Met inhibitor with an IC50 of 0.052 μM against c-Met. It also inhibits the MDR1 and MRP1/2 pumps in cancerous HepG2 and BxPC3 cells. As such, c-Met-IN-23 serves as an anticancer agent.</p>Formula:C16H13N7OMolecular weight:319.118163-Aminopropylphosphinic acid
CAS:<p>3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).</p>Formula:C3H10NO2PColor and Shape:SolidMolecular weight:123.092Analgesic/antidepressant agent-1
<p>Analgesic/antidepressant agent-1 (Compound k1) is an orally active N-acetylamino chloro ketone derivative capable of crossing the blood-brain barrier. It exhibits high affinity for NMDA receptors and demonstrates analgesic, anti-inflammatory, and antidepressant properties, with low psychotomimetic activity.</p>Formula:C22H25ClN2O2Color and Shape:SolidMolecular weight:384.9ProTx II
CAS:<p>Selective NaV1.7 inhibitor, alters activation, reduces current, 100x more selective for 1.7 over other Na+ channels.</p>Formula:C168H250N46O41S8Purity:98%Color and Shape:SolidMolecular weight:3826.59Astressin 2B
CAS:<p>CRF2 antagonist with IC50 of 1.3 nM; >500 nM for CRF1. Aids gastric emptying.</p>Formula:C183H307N49O53Purity:98%Color and Shape:SolidMolecular weight:4041.69Dihydroisopimaric acid
CAS:<p>Dihydroisopimaric acid opens BKαβ1 channels - large Ca²⁺-activated K⁺ conductors, verified by whole-cell voltage clamp.</p>Formula:C20H32O2Color and Shape:SolidMolecular weight:304.47Vedroprevir
CAS:<p>Vedroprevir (GS9451), a selective HCV NS3 protease inhibitor, targets genotype 1 HCV.</p>Formula:C45H60ClN7O9SColor and Shape:SolidMolecular weight:910.53NF864
CAS:<p>NF864, a suramin analog, is a P2X1 receptor inhibitor.</p>Formula:C57H28N6Na12O41S12Purity:98%Color and Shape:SolidMolecular weight:2113.5rac-trans-4-hydroxy Glyburide
CAS:<p>rac-trans-4-hydroxy Glyburide, a metabolite of glyburide, inhibits binding at SUR1/Kir6.2 sites with IC50 values of 0.95 and 100 nM.</p>Formula:C23H28ClN3O6SColor and Shape:SolidMolecular weight:510.0AQP4 (201-220)
CAS:<p>AQP4 (201-220) is the encephalitogenic epitope of AQP-4. AQP4 (201-220) can induce experimental autoimmune encephalomyelitis (EAE), characterized by midline brain lesions, retinal lesions, and lesions at the gray matter/white matter boundary of the spinal cord. AQP-4 is the target antigen in neuromyelitis optica.</p>Formula:C97H143N27O27SColor and Shape:SolidMolecular weight:2151.4N-Arachidonoyl Taurine
CAS:<p>N-Arachidonoyl taurine, an amino acid, activates TRPV1/TRPV4, is metabolized by lipoxygenase, and affects insulin secretion and calcium flux.</p>Formula:C22H37NO4SColor and Shape:SolidMolecular weight:411.6P2X4 antagonist-3
<p>P2X4 antagonist-3 (Compound 14c) is a P2X4 inhibitor with an IC50 value of 1.2 μM. It holds potential for research into neuroinflammation, chronic pain, and cancer progression.</p>Formula:C19H20FN3O4Color and Shape:SolidMolecular weight:373.38JAMI1001A
CAS:<p>JAMI1001A enhances AMPA receptor signaling, slows deactivation/desensitization for flip/flop isoforms.</p>Formula:C16H17F3N4O3SColor and Shape:SolidMolecular weight:402.39PDDHV
CAS:<p>PDDHV: a capsaicin-like vanilloid selective for rat TRPV1; induces Ca2+ uptake in neurons, EC50 of 70 nM.</p>Formula:C49H72O11Color and Shape:SolidMolecular weight:837.09AHN-683
CAS:<p>AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.</p>Formula:C42H32FN3O7Purity:98%Color and Shape:SolidMolecular weight:709.72Hyp9
CAS:<p>Hyp9, a specific agonist for the transient receptor potential canonical 6 (TRPC6) channel, is utilized in spinal cord injury (SCI) research [1].</p>Formula:C18H26O5Color and Shape:SolidMolecular weight:322.40Atagabalin
CAS:<p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>Formula:C10H19NO2Color and Shape:SolidMolecular weight:185.26Cyclic ADP-ribose ammonium
<p>cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.</p>Color and Shape:LiquidChlorotoxin
CAS:<p>Chlorotoxin: 36-amino acid peptide from deathstalker scorpion venom; blocks small chloride channels.</p>Formula:C158H249N53O47S11Purity:98%Color and Shape:SolidMolecular weight:3995.71NSC265473
CAS:<p>NSC265473 is an ABCG2 substrate.</p>Formula:C21H35N3O4SColor and Shape:SolidMolecular weight:425.58Foslevcromakalim
CAS:<p>Foslevcromakalim (QLS-101), an ATP-sensitive potassium channel opener, serves as a proagent for ocular hypotensive effects [1] [2].</p>Formula:C16H19N2O6PColor and Shape:SolidMolecular weight:366.31Antidepressant agent 3
<p>Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.</p>Formula:C17H30ClN5O2SColor and Shape:SolidMolecular weight:403.97Mambalgin 1
CAS:<p>ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.</p>Formula:C272H429N85O84S10Purity:98%Color and Shape:SolidMolecular weight:6554.51ProTx-I
CAS:<p>Selective blocker for CaV3.1 (IC50 = 0.2 μM), CaV3.2 (31.8 μM), also inhibits NaV1.8 and blocks KV2.1 channels.</p>Formula:C171H245N53O47S6Purity:98%Color and Shape:SolidMolecular weight:3987.51N-Oleoyl Glutamine
CAS:<p>N-Oleoyl Glutamine (Oleoyl-L-glutamine) antagonizes TRPV1 of the transient receptor potential (TRP) calcium channel.</p>Formula:C23H42N2O4Purity:99.61%Color and Shape:SolidMolecular weight:410.595-Hydroxy-2′,3,4′,7-tetramethoxyflavone
CAS:<p>5-Hydroxy-2′,3,4′,7-tetramethoxyflavone shows weak ABCG2 inhibitory potency with IC50s of 3.27 and 3.89 µM in the Hoechst 33342 and pheophorbide A assays.</p>Formula:C19H18O7Purity:98%Color and Shape:SoildMolecular weight:358.34(±)17-HETE
CAS:<p>Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.</p>Formula:C20H32O3Color and Shape:SolidMolecular weight:320.473RuBi-GABA
CAS:<p>Ruthenium-bipyridine-triphenylphosphine caged GABA</p>Formula:C42H39F6N5O2P2RuPurity:98%Color and Shape:SolidMolecular weight:922.8Kurtoxin
<p>Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor, exhibiting a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type)</p>Formula:C324H478N94O90S8Purity:98%Color and Shape:SolidMolecular weight:7386.36GSK2332255B
CAS:<p>GSK2332255B: potent TRPC3/6 antagonist; IC50 5 nM (TRPC3), 4 nM (TRPC6); over 100-fold selectivity vs other Ca2+ channels.</p>Formula:C18H19ClFN3O3SColor and Shape:SolidMolecular weight:411.88HG1 Toxin
<p>HG1 Toxin is a peptide found in the venom of the scorpion Heterometrus fulvipes, known for its ability to inhibit the potassium channel Kv1.3 (potassium channel Kv1.3). Additionally, HG1 Toxin exhibits trypsin inhibitory activity (Ki=107 nM), making it useful for research into autoimmune diseases.</p>Formula:C337H503N103O97S6Molecular weight:7736.59176L-Palmitoylcarnitine TFA
<p>L-Palmitoylcarnitine TFA: long-chain fat metabolite that disrupts membranes in ischaemia & inhibits KATP channels via Kir6.2 interaction.</p>Formula:C25H46F3NO6Color and Shape:SolidMolecular weight:513.63Ziconotide
CAS:<p>Ziconotide: analgesic from cone snail for severe, chronic pain; synthetic ω-conotoxin.</p>Formula:C102H172N36O32S7Purity:98%Color and Shape:White PowderMolecular weight:2639.13SC 4453
CAS:<p>SC 4453 is a digoxin analog and a cardiac glycoside derivative.</p>Formula:C41H64N2O12Color and Shape:SolidMolecular weight:776.965APETx2
CAS:<p>ASIC3 inhibitor; IC50: 63 nM (rat), 175 nM (human). Blocks NaV1.8, NaV1.2; analgesic for acid/inflammatory pain.</p>Formula:C196H280N54O61S6Purity:98%Color and Shape:SolidMolecular weight:4561.06Nav1.7-IN-8
CAS:<p>Nav1.7-IN-8 selectively inhibits NaV1.7 over hNaV1.1/1.5, affects CYP2C9/3A4 (IC50: 0.17/0.077 μM), and provides rodent pain relief.</p>Formula:C21H12ClF2N5O4S2Color and Shape:SolidMolecular weight:535.93Levamlodipine besylate Hemipentahydrate
CAS:<p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>Formula:C20H25ClN2O5·C6H6O3SH2OColor and Shape:SolidMolecular weight:1224.18ATP Synthesis-IN-2
<p>ATP Synthesis-IN-2 (Compound 5) serves as a potent inhibitor of ATP synthesis activity, displaying significant antibacterial properties with an IC50 value of 0.</p>Color and Shape:Odour SolidEbio3
<p>Ebio3 is a selective potassium ion channel (KCNQ2) inhibitor with an IC50 of 1.2 nM. It binds to the KCNQ2 channel via its hydrophobic tail, causing the inward movement of the S6 helix, which results in the closure of the internal gate. The inhibitory effect of Ebio3 is equally effective on pathogenic KCNQ2 mutants, such as R75C and I238L, reducing their outward current by approximately 80%. Ebio3 holds potential for research in neurological disorders like epilepsy.</p>Formula:C19H23F2N3O2Color and Shape:SolidMolecular weight:363.4Anticonvulsant agent 9
<p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>Formula:C22H24N4O2Color and Shape:SolidMolecular weight:376.45
