Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(93 products)
- Adiponectin receptor(5 products)
- CFTR(64 products)
- CGRP Receptor(52 products)
- Calcium Channel(496 products)
- Chloride channel(49 products)
- GABA Receptor(336 products)
- Monoamine Transporter(23 products)
- Monocarboxylate transporter(17 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(8 products)
- OAT(27 products)
- OCT(7 products)
- P-gp(53 products)
- Potassium Channel(277 products)
- Proton pump(39 products)
- SGLT(30 products)
- Sodium Channel(202 products)
- TRP/TRPV Channel(93 products)
Show 13 more subcategories
Found 2290 products of "Membrane Transporter/Ion Channel"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
YHO-13351
CAS:YHO-13351 is an ABCG2 inhibitor that induces sensitization of cancer stem cells/initiating-like side population cells to irinotecan.Formula:C27H37N3O7S2Purity:97.88%Color and Shape:SolidMolecular weight:579.73Cinacalcet metabolite M4
CAS:<p>Cinacalcet metabolite M4 (Rarechem AL BW 1078) is a metabolite of Cinacalcet. Cinacalcet is an allosteric agonist of Ca receptor.</p>Formula:C10H12F3NPurity:97.13%Color and Shape:SolidMolecular weight:203.2Pico145
CAS:<p>Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels.</p>Formula:C23H20ClF3N4O5Purity:99.06%Color and Shape:SolidMolecular weight:524.88Acecainide hydrochloride
CAS:<p>Acecainide hydrochloride (NAPA) is the major hepatic metabolite of procainamide.Cost-effective and quality-assured.</p>Formula:C15H24ClN3O2Purity:98.023% - 99.81%Color and Shape:SolidMolecular weight:313.83Tegoprazan
CAS:<p>Tegoprazan is an orally active, highly selective gastric H+/K+-ATPase inhibitor.Cost-effective and quality-assured.</p>Formula:C20H19F2N3O3Purity:98.22%Color and Shape:SolidMolecular weight:387.38HC067047 Hydrochloride(883031-03-6 free base)
CAS:HC-067047 hydrochloride, a TRPV4 antagonist, selectively inhibits human, rat, and mouse currents with IC50s: 486 nM, 133 nM, and 17 nM.Formula:C26H29ClF3N3O2Purity:99.95%Color and Shape:SolidMolecular weight:507.98Dotinurad
CAS:Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid).Formula:C14H9Cl2NO4SPurity:97.43% - 98.04%Color and Shape:SolidMolecular weight:358.2DL-Willardiine
CAS:<p>DL-Willardiine (2-amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid) is an unnatural amino acid, a derivative of glutamate.</p>Formula:C7H9N3O4Purity:99.83%Color and Shape:SolidMolecular weight:199.16ML277
CAS:<p>ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).</p>Formula:C23H25N3O4S2Purity:99.35%Color and Shape:SolidMolecular weight:471.59A2793
CAS:<p>A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM.</p>Formula:C13H12ClNO3Purity:98.54%Color and Shape:SolidMolecular weight:265.69CX614
CAS:<p>CX614 is a positive allosteric modulator of the AMPA receptor concerning AMPA.</p>Formula:C13H13NO4Purity:97.37%Color and Shape:SolidMolecular weight:247.255,7-Dichlorokynurenic acid
CAS:5,7-Dichlorokynurenic acid (5,7-dichlorokynurenic acid sodium) is an NMDA receptor antagonist.Formula:C10H5Cl2NO3Purity:99.71%Color and Shape:SolidMolecular weight:258.06TC-I2000
CAS:<p>TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells with IC50 of 53 nM.</p>Formula:C23H18F4N2OPurity:99.778%Color and Shape:SolidMolecular weight:414.4S107
CAS:<p>S107 stabilizes RyR2 by improving calstabin2 binding to mutant/PKA-phosphorylated channels.</p>Formula:C11H15NOSPurity:99.90%Color and Shape:SolidMolecular weight:209.31PF-01247324
CAS:<p>PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).</p>Formula:C13H10Cl3N3OPurity:99.22%Color and Shape:SolidMolecular weight:330.6Quadrol
CAS:<p>Quadrol (EDTP) is an immunostimulant, accelerated wound healing.</p>Formula:C14H32N2O4Purity:99.91% - 99.92%Color and Shape:Viscous Liquid Liquid ViscousMolecular weight:292.41Vanillyl butyl ether
CAS:<p>Vanillyl butyl ether (Butyl vanillyl ether) (VBE)is a capsaicin analogue,induce sensory irritation in humans,Vanillyl butyl ether is an alkoxy-substituted</p>Formula:C12H18O3Purity:99.57%Color and Shape:Yellowish Liquid LiquidMolecular weight:210.27VU0071063
CAS:VU0071063 is a Kir6.2/SUR1 activator.Formula:C18H22N4O2Purity:99.33%Color and Shape:SolidMolecular weight:326.39(2S)-6-Prenylnaringenin
CAS:<p>(2S)-6-Prenylnaringenin (6-Prenylnaringenin) is an isomer of the potent phytoestrogen, 8-prenylnaringenin.</p>Formula:C20H20O5Purity:99.47%Color and Shape:SolidMolecular weight:340.37Amifampridine phosphate
CAS:<p>Amifampridine treats rare muscle diseases like LEMS and congenital myasthenias, targeting specific enzyme defects.</p>Formula:C5H10N3O4PColor and Shape:SolidMolecular weight:207.12IDRA-21
CAS:IDRA-21 is a positive AMPA receptor modulator.Formula:C8H9ClN2O2SPurity:99.73%Color and Shape:SolidMolecular weight:232.69Guan-fu base A hydrochloride(1394-48-5 free base)
CAS:<p>Guanfu base A HCl, an antiarrhythmic from Aconitum coreanum, inhibits CYP2D6 in humans, monkeys, and dogs.</p>Formula:C24H32NO6ClPurity:99.9%Color and Shape:SolidMolecular weight:465.97Pyr10
CAS:<p>Pyr10, a pyrazole derivative, selectively inhibits TRPC3, not STIM1/Orai1, with IC50 of 0.72 μM in TRPC3-HEK293, and 13.08 μM in BRL-2H3 cells.</p>Formula:C18H13F6N3O2SPurity:99.69% - 99.7%Color and Shape:SolidMolecular weight:449.37VX-150
CAS:<p>VX-150 is a highly selective NaV1.8 inhibitor relative to the other sodium channel subtypes (>400-fold).</p>Formula:C21H17F4N2O7PPurity:97.58%Color and Shape:SolidMolecular weight:516.34Cis-ACBD
CAS:<p>Cis-ACBD (cis-1-aminocyclobutane-1,3-dicarboxylic acid) is a potent and selective N-methyl-D-aspartate receptor agonist.</p>Formula:C6H9NO4Purity:99.77%Color and Shape:SolidMolecular weight:159.14Parimifasor
CAS:<p>Parimifasor (LYC30937) is an immunomodulator, with anti-inflammatory activity.</p>Formula:C18H11Cl2F4N5OPurity:96.77% - 98.97%Color and Shape:SolidMolecular weight:460.21α-Thujone
CAS:<p>α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.</p>Formula:C10H16OPurity:97.02% - 98.41%Color and Shape:Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Molecular weight:152.23Eperisone hydrochloride
CAS:<p>Eperisone is a skeletal muscle relaxant and a spasmolytic agent related structurally to Tolperisone.</p>Formula:C17H26ClNOPurity:99.80%Color and Shape:White Or Similar To White Crystalline Powder With Peculiar Smell And Bitter TasteMolecular weight:295.85Benzamil
CAS:<p>Benzamil blocks ENaC, inhibiting sodium transport (IC50=4 nM) and binds with Kd=5 nM to bovine kidney membranes.</p>Formula:C13H14ClN7OPurity:99.79%Color and Shape:SolidMolecular weight:319.75KB-R7943 mesylate
CAS:<p>KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.</p>Formula:C17H21N3O6S2Purity:99.88% - ≥95%Color and Shape:SolidMolecular weight:427.5Benzocaine xHCl(94-09-7(free base))
<p>Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).</p>Formula:C9H11NO2·xHClPurity:99.37%Color and Shape:SolidMolecular weight:N/AMitiglinide calcium hydrate
CAS:<p>Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes.</p>Formula:C38H52CaN2O8Purity:98.97% - 99.96%Color and Shape:White SolidMolecular weight:704.91Argireline
CAS:<p>Argireline (Acetyl hexapeptide-3) is a peptide that inhibits neurotransmitter release, reducing wrinkles.</p>Formula:C34H60N14O12SPurity:96.79% - 99.65%Color and Shape:White PowderMolecular weight:888.99DAAO inhibitor-1
CAS:<p>DAAO inhibitor-1 is a potent D-amino acid oxidase (DAAO) inhibitor (IC50: 0.12 μM).</p>Formula:C7H5FN2OPurity:97.84%Color and Shape:SolidMolecular weight:152.13Cholesterol myristate
CAS:<p>Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.</p>Formula:C41H72O2Purity:99.65%Color and Shape:SolidMolecular weight:597.01BRITE-338733
CAS:<p>BRITE-338733 is a novel inhibitor of ATPase. BRITE 338733 inhibits the expression of RecA in bacteria (IC50=4.7 μM) for the bacterial infections treatment.</p>Formula:C27H35N3O2Purity:99.85%Color and Shape:SolidMolecular weight:433.59Lumacaftor
CAS:<p>Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein.</p>Formula:C24H18F2N2O5Purity:99.48% - 99.68%Color and Shape:SolidMolecular weight:452.41SG-209
CAS:<p>SG 209 is an analog of nicorandil and acts as a K+ channel opener and nitrate-free coronary vasodilator.</p>Formula:C10H12N2O3Purity:99.84%Color and Shape:SolidMolecular weight:208.21DQP 1105
CAS:<p>DQP 1105 is a NMDA receptor antagonist.</p>Formula:C29H24BrN3O4Purity:98.6%Color and Shape:SolidMolecular weight:558.42Drotaverine hydrochloride
CAS:<p>Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor，and is an antispasmodic drug, used to enhance cervical dilation</p>Formula:C24H32ClNO4Purity:99.81%Color and Shape:Pale-Yellow Crystalline SolidMolecular weight:433.968Chembridge-5861528
CAS:<p>Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 values of 14.3 and 18.7 μM.</p>Formula:C19H23N5O3Purity:99.97%Color and Shape:SolidMolecular weight:369.42JNJ-17203212
CAS:JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 of 65 nM and 102 nM).Formula:C17H15F6N5OPurity:99.18%Color and Shape:SolidMolecular weight:419.32Imidazenil
CAS:<p>Imidazenil is an modulator of GABA-A that blocks the sedative effects without lowering the convulsion threshold.</p>Formula:C18H12BrFN4OPurity:98.4%Color and Shape:SolidMolecular weight:399.22GMQ hydrochloride
CAS:<p>GMQ hydrochloride, a potent ASIC modulator, activates ASIC3 at neutral pH and inhibits acid-induced peak current.</p>Formula:C10H12ClN5Purity:99.64%Color and Shape:SolidMolecular weight:237.69Gabazine free base
CAS:<p>Gabazine free base is a specific antagonist of the GABA receptor. It does not affect GABA-transaminase or glutamate-decarboxylase activities.</p>Formula:C15H17N3O3Color and Shape:SolidMolecular weight:287.31AZ194
CAS:<p>CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.</p>Formula:C34H31F2N3O3Purity:99.61%Color and Shape:SolidMolecular weight:567.62Piperazine citrate
CAS:<p>Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring.</p>Formula:C24H46N6O14Purity:99.8%Color and Shape:Crystals IndicationMolecular weight:642.65Icenticaftor
CAS:Icenticaftor (QBW251) is an orally active potentiator of CFTR channel.Formula:C12H13F6N3O3Purity:99.76%Color and Shape:SolidMolecular weight:361.24Temgicoluril
CAS:<p>Temgicoluril (mebikar) acts on GABA Receptor.</p>Formula:C8H14N4O2Purity:99.8%Color and Shape:SolidMolecular weight:198.22Trofinetide
CAS:Trofinetide (NNZ-2566) is a synthetic analog of the endogenous N-terminus tripeptide. It has been shown to be neuroprotective in animal models of brain injury.Formula:C13H21N3O6Purity:98.70% - 99.50%Color and Shape:SolidMolecular weight:315.32
