CymitQuimica logo
GABA Receptor

GABA Receptor

GABA receptors are the primary inhibitory neurotransmitter receptors in the central nervous system, playing a critical role in regulating neuronal excitability and maintaining the balance between excitation and inhibition. GABA receptor dysfunction is implicated in various neurological and psychiatric disorders, including epilepsy, anxiety, and depression. At CymitQuimica, we provide a comprehensive range of GABA receptor modulators to support your research in neurobiology, mental health, and therapeutic development.

Found 336 products of "GABA Receptor"

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Pentetrazol

    CAS:
    <p>Pentylenetetrazol is a GABA(A) receptor antagonist, that displays activity as a central nervous system and respiratory stimulant.</p>
    Formula:C6H10N4
    Purity:99.7% - >99.99%
    Color and Shape:Bitter Taste Aqueous Solutions Neutral To Litmus (Ntp 1992)
    Molecular weight:138.17
  • Pivagabine

    CAS:
    <p>Pivagabine (CXB-722), a 4-aminobutyric acid derivative, modulates GABA, CRF, and crosses the rat blood-brain barrier.</p>
    Formula:C9H17NO3
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:187.24
  • Phenelzine sulfate

    CAS:
    <p>Phenelzine sulfate is a non-selective and irreversible inhibitor of monoamine oxidase (MAOI), and with antidepressant and anxiolytic.</p>
    Formula:C8H14N2O4S
    Purity:98.38% - 99.83%
    Color and Shape:Solid
    Molecular weight:234.27
  • Isoguvacine hydrochloride

    CAS:
    <p>Isoguvacine hydrochloride (1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride) is a GABA receptor agonist.</p>
    Formula:C6H10ClNO2
    Purity:99.59%
    Color and Shape:Solid
    Molecular weight:163.6
  • Baclofen

    CAS:
    <p>Baclofen (Lioresal), a chlorophenyl-butanoic acid derivative, treats spasms from spinal cord injury and MS by mimicking GABA at GABA-B receptors.</p>
    Formula:C10H12ClNO2
    Purity:98% - >99.99%
    Color and Shape:1992)
    Molecular weight:213.66
  • Broflanilide

    CAS:
    <p>Broflanilide metabolite desmethyl-broflanilide blocks GABA receptor in dieldrin-resistant insects, inhibiting S. litura at IC50 1.3 nM.</p>
    Formula:C25H14BrF11N2O2
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:663.29
  • γ-Aminobutyric acid

    CAS:
    <p>γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system.</p>
    Formula:C4H9NO2
    Purity:99.95%
    Color and Shape:White Or Almost White(According To Quality Test Specification It Can Be White Or Almost White ) Solid Powder
    Molecular weight:103.12
  • Afoxolaner

    CAS:
    <p>Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs.</p>
    Formula:C26H17ClF9N3O3
    Purity:99.1% - 99.38%
    Color and Shape:Solid
    Molecular weight:625.87
  • Nikethamide

    CAS:
    <p>Nikethamide is a stimulant which mainly influences the respiratory cycle. Widely known by its former sales name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overtreatments, before the advent of end</p>
    Formula:C10H14N2O
    Purity:99.42%
    Color and Shape:Followed By A Faint Sensation Of The Warmth (Ntp 1992)
    Molecular weight:178.23
  • Clomethiazole

    CAS:
    <p>Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It has potential for treating convulsive status epilepticus.</p>
    Formula:C6H8ClNS
    Purity:99.06%
    Color and Shape:Solid
    Molecular weight:161.65
  • NEO 376

    CAS:
    <p>NEO 376 (SPI-376) is a selective 5-HT1 receptor, GABA receptor and dopamine receptor modulator, showing anti-psychotic actively.</p>
    Formula:C20H24ClN3O
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:357.88
  • Fluxametamide

    CAS:
    <p>Fluxametamide, an isoxazoline insecticide, targets insect chloride channels with IC50s of 1.95 nM (GABA) and 225 nM (glutamate).</p>
    Formula:C20H16Cl2F3N3O3
    Purity:99.49%
    Color and Shape:Solid
    Molecular weight:474.26
  • Phenibut

    CAS:
    <p>Phenibut (Aminophenylbutyric acid) is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA).</p>
    Formula:C10H13NO2
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:179.22
  • Lotilaner

    CAS:
    <p>Lotilaner is a parasiticide.</p>
    Formula:C20H14Cl3F6N3O3S
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:596.76
  • Nefiracetam

    CAS:
    <p>Nefiracetam (DM9384), in Phase 2 trials, enhances GABA, choline, monoamine systems, and treats Ro 5-4864 convulsions.</p>
    Formula:C14H18N2O2
    Purity:97.37%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:246.3
  • Oxiracetam

    CAS:
    <p>Oxiracetam (ISF2522), a cyclic derivative of gamma-aminobutyric acid (GABA), is utilized for the treatment of cognitive impairments.</p>
    Formula:C6H10N2O3
    Purity:99.67%
    Color and Shape:White Crystalline Powder
    Molecular weight:158.16
  • FG 7142

    CAS:
    <p>FG 7142 (LSU-65), a benzodiazepine inverse agonist, targets α1 subunit GABAA receptors (EC50=137 nM, Ki=91 nM) and upregulates β-adrenoceptors.</p>
    Formula:C13H11N3O
    Purity:98.75%
    Color and Shape:Solid
    Molecular weight:225.25
  • Flumazenil

    CAS:
    <p>Flumazenil (Ro 15-1788) antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous</p>
    Formula:C15H14FN3O3
    Purity:99.72% - 99.98%
    Color and Shape:Less Crystals Colourless Crystals
    Molecular weight:303.29
  • L-Cycloserine

    CAS:
    <p>L-Cycloserine irreversibly inhibits E. coli GABA aminotransferase, raising GABA levels, an inhibitory neurotransmitter.</p>
    Formula:C3H6N2O2
    Purity:99.45% - 99.92%
    Color and Shape:Crystals White Powder
    Molecular weight:102.09
  • LAU159

    CAS:
    <p>LAU159 is a functionally selective positive α1β3 GABA(A) receptor modulator(EC50 : 2.2 μM).</p>
    Formula:C17H12ClN3O2
    Purity:98.7% - 99.38%
    Color and Shape:Solid
    Molecular weight:325.75
  • Bemegride

    CAS:
    <p>Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning.</p>
    Formula:C8H13NO2
    Purity:99.89%
    Color and Shape:Physical Description White Crystalline Solid Sublimes At 212°F And 200 Mm Pressure (Ntp 1992)
    Molecular weight:155.19
  • Topiramate

    CAS:
    <p>Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.</p>
    Formula:C12H21NO8S
    Purity:99.79% - 99.92%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:339.36
  • GABAA receptor agent 1

    CAS:
    <p>GABAA receptor agent 1 has strong anticonvulsant activity and is a high affinity ligand of GABAA receptor.</p>
    Formula:C13H8ClN3O2
    Purity:99.31%
    Color and Shape:Solid
    Molecular weight:273.67
  • Domperidone EP Impurity A

    CAS:
    <p>Domperidone EP Impurity A is used as pharmaceutical intermediates.</p>
    Formula:C12H14ClN3O
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:251.71
  • GET73

    CAS:
    <p>GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5.</p>
    Formula:C13H16F3NO2
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:275.27
  • 3,4,5-Trimethoxycinnamic acid

    CAS:
    <p>3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the</p>
    Formula:C12H14O5
    Purity:98.91%
    Color and Shape:Solid
    Molecular weight:238.24
  • Emamectin Benzoate

    CAS:
    <p>Emamectin Benzoate (MK-244), by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods</p>
    Formula:C56H81NO15
    Purity:98.68%
    Color and Shape:Solid
    Molecular weight:1008.256
  • Chlormezanone

    CAS:
    <p>Chlormezanone (Trancopal) is a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.</p>
    Formula:C11H12ClNO3S
    Purity:99.89% - >99.99%
    Color and Shape:Crystals Solid
    Molecular weight:273.74
  • Vigabatrin

    CAS:
    <p>Vigabatrin (Sabril), an analogue of gamma-aminobutyric acid, is an irreversible inhibitor of 4-aminobutyrate Transaminase responsible for the catabolism of γ-</p>
    Formula:C6H11NO2
    Purity:99.47% - 99.88%
    Color and Shape:Solid
    Molecular weight:129.16
  • Etifoxine hydrochloride

    CAS:
    <p>Etifoxine hydrochloride (HOE 36-801 hydrochloride) is an anxiolytic and anticonvulsant drug.</p>
    Formula:C17H18Cl2N2O
    Purity:99.36%
    Color and Shape:Solid
    Molecular weight:337.24
  • 3-Aminopropylphosphinic acid

    CAS:
    <p>3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).</p>
    Formula:C3H10NO2P
    Color and Shape:Solid
    Molecular weight:123.092
  • Emamectin B1a

    CAS:
    <p>Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.</p>
    Formula:C49H75NO13
    Color and Shape:Solid
    Molecular weight:886.133
  • LU-32-176B

    CAS:
    <p>LU32-176B is a bioactive chemical.</p>
    Formula:C23H24F2N2O2
    Color and Shape:Solid
    Molecular weight:398.45
  • Pyrazolam

    CAS:
    <p>Pyrazolam is a psychoactive benzodiazepine compound serving as a central nervous system depressant. [Pyrazolam] can lead to psychomotor impairment.</p>
    Formula:C16H12BrN5
    Color and Shape:Solid
    Molecular weight:354.2
  • Anisatin


    <p>Anisatin is a useful organic compound for research related to life sciences and the catalog number is T124719.</p>
    Formula:C15H20O8
    Color and Shape:Solid
    Molecular weight:328.317
  • GABA receptor Antagonist 1


    <p>GABA receptor Antagonist 1 (compound 7w) effectively inhibits the Px RDL1 GABAR at an IC50 of 7.08 nmol/L and demonstrates insecticidal efficacy against P.</p>
    Purity:98%
    Color and Shape:Odour Solid
  • DAA-1106

    CAS:
    <p>DAA-1106 is a potent and selective ligand for PBR, acting as a potent and selective agonist at the peripheral benzodiazepine receptor.</p>
    Formula:C23H22FNO4
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:395.42
  • Guvacine hydrobromide

    CAS:
    <p>Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake.</p>
    Formula:C6H10BrNO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:208.05
  • Desalkylgidazepam

    CAS:
    <p>Desalkylgidazepam, a benzodiazepine compound, is a metabolite of gidazepam. It is capable of activating both GABA A-type receptors and the translocator protein (TSPO).</p>
    Formula:C15H11BrN2O
    Color and Shape:Solid
    Molecular weight:315.17
  • Flufiprole

    CAS:
    <p>Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.</p>
    Formula:C16H10Cl2F6N4OS
    Color and Shape:Solid
    Molecular weight:491.24
  • TET-13


    <p>TET-13 is a positive allosteric modulator of the GABAA receptor with an EC50 of 5.65 μM, which is more potent than Etomidate (EC50: 9.29 μM). It exhibits strong anesthetic effects in both mice and rats, with an ED50 of 0.48 mg/kg in mice and 0.69 mg/kg in rats.</p>
    Formula:C15H16N2O3S
    Color and Shape:Solid
    Molecular weight:304.36
  • AHN-683

    CAS:
    <p>AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.</p>
    Formula:C42H32FN3O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:709.72
  • Antidepressant agent 4


    <p>Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.</p>
    Formula:C19H38ClN5O2S
    Color and Shape:Solid
    Molecular weight:436.06
  • Azocarnil


    <p>Azocarnil is a GABAergic agonist-enhancer used in neurological system research.</p>
    Color and Shape:Odour Solid
  • Nitrazolam

    CAS:
    <p>Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.</p>
    Formula:C17H13N5O2
    Color and Shape:Solid
    Molecular weight:319.32
  • Anticonvulsant agent 8


    <p>Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.</p>
    Formula:C15H11N5O
    Color and Shape:Solid
    Molecular weight:277.28
  • α5-GABAA receptor modulator 1


    <p>α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.</p>
    Formula:C21H20FN3O4
    Color and Shape:Solid
    Molecular weight:397.4
  • Imagabalin

    CAS:
    <p>Imagabalin is an active compound used in the study of neurological diseases.</p>
    Formula:C9H19NO2
    Color and Shape:Solid
    Molecular weight:173.25
  • Rilmazolam

    CAS:
    <p>Rilmazolam is a triazolobenzodiazepine compound and serves as the active metabolite of Rilmazafone.</p>
    Formula:C19H15Cl2N5O
    Color and Shape:Solid
    Molecular weight:400.26
  • 3-Hydroxy desalkylflurazepam

    CAS:
    <p>3-Hydroxy desalkylflurazepam is a benzodiazepine compound with potential sedative and anxiolytic effects.</p>
    Formula:C15H10ClFN2O2
    Color and Shape:Solid
    Molecular weight:304.7
  • Furosemide sodium

    CAS:
    <p>Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.</p>
    Formula:C12H10ClN2NaO5S
    Purity:99.52% - >99.99%
    Color and Shape:Solid
    Molecular weight:352.73
  • Withasomniferolide B

    CAS:
    <p>Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.</p>
    Formula:C28H36O4
    Color and Shape:Solid
    Molecular weight:436.58
  • Neurotransmitter Receptor Compound Library


    <p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening;</p>
    Color and Shape:Odour Solid
  • CGP 35348

    CAS:
    <p>CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化新生小鼠脑损伤后的神经肌肉协调和空间学习。</p>
    Formula:C8H20NO4P
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:225.22
  • Antidepressant agent 3


    <p>Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.</p>
    Formula:C17H30ClN5O2S
    Color and Shape:Solid
    Molecular weight:403.97
  • Endosulfan I

    CAS:
    <p>Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complex</p>
    Formula:C9H6Cl6O3S
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:406.93
  • Ion Channel Targeted Library


    <p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>
    Color and Shape:Odour Solid
  • Anticonvulsant agent 9


    <p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>
    Formula:C22H24N4O2
    Color and Shape:Solid
    Molecular weight:376.45
  • Nipecotic acid

    CAS:
    <p>Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formula:C6H11NO2
    Color and Shape:Off-White To Pale Yellow-Beige Powder
    Molecular weight:129.16
  • α-Casozepine

    CAS:
    <p>α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.</p>
    Formula:C60H94N14O16
    Color and Shape:Solid
    Molecular weight:1267.47
  • Atagabalin

    CAS:
    <p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>
    Formula:C10H19NO2
    Color and Shape:Solid
    Molecular weight:185.26
  • Brexanolone caprilcerbate

    CAS:
    <p>Brexanolone caprilcerbate is an effective positive allosteric modulator of the GABAA receptor.</p>
    Formula:C48H78O12
    Color and Shape:Solid
    Molecular weight:847.13
  • Inaperisone

    CAS:
    <p>Inaperisone: a novel muscle relaxant that indirectly inhibits voiding reflex via brainstem GABAB receptors.</p>
    Formula:C16H23NO
    Purity:99.48%
    Color and Shape:Solid
    Molecular weight:245.36
  • MIDD0301

    CAS:
    <p>MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.</p>
    Formula:C19H13BrFN3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:414.23
  • 3-Aminopropylphosphonic Acid

    CAS:
    <p>3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding</p>
    Formula:C3H10NO3P
    Purity:99.84%
    Color and Shape:Light Yellow Liquid
    Molecular weight:139.09
  • epi-Aszonalenin A

    CAS:
    <p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>
    Formula:C25H25N3O3
    Color and Shape:Solid
    Molecular weight:415.48
  • Cinazepam

    CAS:
    <p>Cinazepam is a GABAA receptor partial agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders.</p>
    Formula:C19H14BrClN2O5
    Color and Shape:Solid
    Molecular weight:465.68
  • GABAA receptor modulator-4


    <p>GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.</p>
    Formula:C15H17BrO4S
    Color and Shape:Solid
    Molecular weight:373.26
  • GABAA receptor modulator-3


    <p>GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.</p>
    Formula:C18H22O2
    Color and Shape:Solid
    Molecular weight:270.37
  • FGIN-1-43

    CAS:
    <p>FGIN-1-43 is a potent and specific ligand for the mitochondrial DBI receptor.</p>
    Formula:C28H36Cl2N2O
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:487.5
  • 6,7-dimethylisatin

    CAS:
    <p>6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.</p>
    Formula:C10H9NO2
    Purity:98.98%
    Color and Shape:Solid
    Molecular weight:175.18
  • 12,14-Dichlorodehydroabietic acid

    CAS:
    <p>12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.</p>
    Formula:C20H26Cl2O2
    Color and Shape:Solid
    Molecular weight:369.33
  • Fipronil sulfone

    CAS:
    <p>Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.</p>
    Formula:C12H4Cl2F6N4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:453.14
  • Chrodrimanin B

    CAS:
    <p>Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.</p>
    Formula:C27H32O8
    Color and Shape:Solid
    Molecular weight:484.545
  • (Iso)-Atagabalin HCl

    CAS:
    <p>(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.</p>
    Formula:C10H20ClNO2
    Purity:99.26% - >99.99%
    Color and Shape:Soild
    Molecular weight:221.72
  • Riluzole-13C,15N2

    CAS:
    <p>Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.</p>
    Formula:CC7H5F3OS15N2
    Color and Shape:Solid
    Molecular weight:237.18
  • Lesogaberan napadisylate

    CAS:
    <p>Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.</p>
    Formula:C13H17FNO5PS
    Color and Shape:Solid
    Molecular weight:349.31
  • GABA-A Receptor Ligand-1


    <p>GABA-A Receptor Ligand-1 (Compound 4) is a ligand for the GABA-A receptor with a pKi of 7.27. It alleviates mitochondrial dysfunction, promotes neurite outgrowth and neuronal regeneration, and demonstrates neuroprotective effects in a rat ischemic stroke model.</p>
    Formula:C20H20FN3O
    Color and Shape:Solid
    Molecular weight:337.391
  • Furosemide

    CAS:
    <p>Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used for edema and chronic renal insufficiency.</p>
    Formula:C12H11ClN2O5S
    Purity:99.32% - 99.89%
    Color and Shape:Crystals From Aqueous Ethanol Tasteless (Ntp 1992)
    Molecular weight:330.744
  • RuBi-GABA

    CAS:
    <p>Ruthenium-bipyridine-triphenylphosphine caged GABA</p>
    Formula:C42H39F6N5O2P2Ru
    Purity:98%
    Color and Shape:Solid
    Molecular weight:922.8
  • (1S,3R)-3-Aminocyclopentane carboxylic acid

    CAS:
    <p>(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.</p>
    Formula:C6H11NO2
    Color and Shape:Solid
    Molecular weight:129.16
  • Etifoxine

    CAS:
    <p>Etifoxine targets β2/β3 GABAA receptors, is anxiolytic in humans/rodents, boosts GABAA, binds TSPO, aids axon regeneration, no sedative effects.</p>
    Formula:C17H17ClN2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:300.78
  • Padsevonil

    CAS:
    <p>Padsevonil (UCB-0942) is a potential GABA A receptor orthosteric modulator with antiepileptic activity for the treatment of epilepsy.</p>
    Formula:C14H14ClF5N4O2S
    Purity:99.63%
    Color and Shape:Solid
    Molecular weight:432.80
  • MRK-016

    CAS:
    <p>MRK-016 is a selective GABAA α5 receptor inverse agonist/ negative allosteric modulator, orally available and penetrating the BBB. MRK-016 is antidepressant.</p>
    Formula:C17H20N8O2
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:368.39
  • Propanidid

    CAS:
    <p>Propanidid (Sombrevin) is a gamma-aminobutyric acid type A receptor (GABAA) agonist and an intravenous anesthetic that lowers arterial blood pressure.</p>
    Formula:C18H27NO5
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:337.41
  • TACA

    CAS:
    <p>GABAA agonist</p>
    Formula:C4H7NO2
    Purity:98%
    Color and Shape:White Solid
    Molecular weight:101.1
  • Valnoctamide

    CAS:
    <p>Valnoctamide (Valmethamide) has antiepileptic and anticonvulsant activity and may be used in the study of neurological disorders.</p>
    Formula:C8H17NO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:143.23
  • Vigabatrin Hydrochloride

    CAS:
    <p>Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the GABA, irreversibly inhibiting the catabolism of GABA by GABA transaminase.</p>
    Formula:C6H11NO2·HCl
    Purity:98%
    Color and Shape:Solid
    Molecular weight:165.62
  • Dipropofol

    CAS:
    <p>Dipropofol (4,4-Bis(2,6-di-isopropylphenol)) is a small molecule GABAA receptor agonist that can be used to study epilepsy.</p>
    Formula:C24H34O2
    Purity:99.51%
    Color and Shape:Solid
    Molecular weight:354.53
  • L-655708

    CAS:
    <p>L-655708 is a selective and highly potent GABAA receptor reverse agonist with a Ki value of 0.45 nM.</p>
    Formula:C18H19N3O4
    Purity:98.41%
    Color and Shape:Powder
    Molecular weight:341.36
  • CGP 36742

    CAS:
    <p>CGP 36742 blocks GABAB receptor, crosses blood-brain barrier, aids depression treatment (IC50: 32 μM).</p>
    Formula:C7H18NO2P
    Color and Shape:Solid
    Molecular weight:179.2
  • (-)-α-Pinene

    CAS:
    <p>(-)-α-Pinene ((1S)-(-)-Alpha-Pinene) enhances the quantity of NREMS without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission,</p>
    Formula:C10H16
    Purity:98.02% - 98.60%
    Color and Shape:Colourless Liquid
    Molecular weight:136.23
  • Furosemide-d5

    CAS:
    <p>Furosemide-d5 is a deuterium marker for Furosemide and used in isotope tracer experiments. orally active inhibitor of Na+/K+/2Cl- (NKCC) diuretic reagent.</p>
    Formula:C12H11ClN2O5S
    Color and Shape:Solid
    Molecular weight:335.78
  • Ocinaplon

    CAS:
    <p>Ocinaplon (DOV 273547) is a GABAA receptors modulator.</p>
    Formula:C17H11N5O
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:301.3
  • Isoflurane

    CAS:
    <p>Isoflurane (Forane) is a stable, non-explosive inhalation anesthetic that has been reported to induce caspase-3 activation.</p>
    Formula:C3H2ClF5O
    Purity:98%
    Color and Shape:Clear Colorless Liquid Liquid
    Molecular weight:184.49
  • Ginkgolide A

    CAS:
    <p>Ginkgolide A (BN-52020), from Ginkgo biloba leaves, is an active PAF antagonist with potential in treating inflammation and immune disorders.</p>
    Formula:C20H24O9
    Purity:98.76% - 99.81%
    Color and Shape:White Powder
    Molecular weight:408.4
  • Imidazenil

    CAS:
    <p>Imidazenil is an modulator of GABA-A that blocks the sedative effects without lowering the convulsion threshold.</p>
    Formula:C18H12BrFN4O
    Purity:98.4%
    Color and Shape:Solid
    Molecular weight:399.22
  • γ-Acetylenic GABA

    CAS:
    <p>γ-Acetylenic GABA (4-Aminohex-5-ynoic acid) is a potent, irreversible inhibitor of GABA-transaminase.</p>
    Formula:C6H9NO2
    Color and Shape:Solid
    Molecular weight:127.143
  • 4-Acetamidobutanoic acid

    CAS:
    <p>4-Acetamidobutanoic acid, a GABA derivative in eukaryotes, found in blood, feces, urine, and human prostate.</p>
    Formula:C6H11NO3
    Purity:98.51%
    Color and Shape:Solid
    Molecular weight:145.16
  • (R)-baclofen

    CAS:
    <p>(R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.</p>
    Formula:C10H12ClNO2
    Purity:97.20% - 98.94%
    Color and Shape:Solid
    Molecular weight:213.66