Factor Xa
Factor Xa is a crucial enzyme in the coagulation cascade that converts prothrombin to thrombin, leading to blood clot formation. Inhibition of Factor Xa is a widely used therapeutic strategy for preventing and treating thromboembolic disorders, such as deep vein thrombosis, pulmonary embolism, and stroke. At CymitQuimica, we offer Factor Xa inhibitors to support your research in hematology, cardiovascular health, and anticoagulant therapy.
Found 87 products of "Factor Xa"
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Letaxaban
CAS:Letaxaban (TAK-442) is a small molecule Xa factor inhibitor that can be used to study polar coronary syndromes and thrombotic blockages.Formula:C22H26ClN3O5SPurity:99.13% - 99.87%Color and Shape:SolidMolecular weight:479.98Ciraparantag acetate
CAS:Ciraparantag acetate reverses anticoagulation, binding heparins and DOACs noncovalently.Formula:C24H52N12O4Purity:99.65%Color and Shape:SolidMolecular weight:572.75Ref: TM-T10820L1
2mg46.00€5mg66.00€10mg97.00€25mg188.00€50mg311.00€100mg512.00€1mL*10mM (DMSO)107.00€Osocimab
CAS:Osocimab (BAY 1213790) is a strong FXIa inhibitor, Ki 2.4 nM, EC50 0.2 nM, and reduces thrombosis in research.
Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:144.46 kDa5-R-Rivaroxaban
CAS:5-R-Rivaroxaban is the (R)-enantiomer of Rivaroxaban, a potent FXa inhibitor with IC50 0.7 nM and Ki 0.4 nM.
Formula:C19H18ClN3O5SPurity:99.75%Color and Shape:SolidMolecular weight:435.88Gabexate mesylate
CAS:Gabexate mesylate (FOY) inhibits thrombin, plasmin, kallikrein; used for pancreatitis, DIC, hemodialysis anticoagulant.Formula:C17H27N3O7SPurity:99.2% - 99.64%Color and Shape:White CrystalMolecular weight:417.482-Methoxyphenothiazine
CAS:2-Methoxy Phenothiazine is light yellow or light gray solid.Formula:C13H11NOSPurity:99.28%Color and Shape:Orange Yellow Crystal PowderMolecular weight:229.3Garadacimab
CAS:Garadacimab (CSL312) is a human IgG4 antibody against FXIIa, used to research hereditary angioedema.Purity:SDS-PAGE:95% SEC-HPLC:99.99%Color and Shape:LiquidMolecular weight:146.5 kDaRivaroxaban
CAS:Rivaroxaban (BAY 59-7939) is an oral, direct factor Xa inhibitor with anticoagulant properties, interfering with thrombin formation.Formula:C19H18ClN3O5SPurity:99.93% - >99.99%Color and Shape:SolidMolecular weight:435.88Ref: TM-T1184
2mg35.00€5mg52.00€10mg70.00€25mg95.00€50mg118.00€100mg178.00€200mg264.00€1mL*10mM (DMSO)58.00€Canine Factor Xa
CanineFactor Xa is derived from purified Canine Factor X through activation by Russell's Viper Venom, after which the venom is removed.Color and Shape:Odour SolidRabbit Factor Xa
RabbitFactor Xa is produced from purified Rabbit Factor X through activation by Russells' Viper Venom, followed by the removal of the venom.Color and Shape:Odour SolidCH3OCO-D-CHA-Gly-Arg-pNA acetate
CAS:CH3OCO-D-CHA-Gly-Arg-pNA acetate serves as a chromogenic substrate for Factor Xa, as documented in sources [1] [2].Formula:C27H42N8O9Purity:98%Color and Shape:SolidMolecular weight:622.67O-Desmethyl apixaban sulfate sodium
O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.Formula:C24H22N5NaO7SPurity:98%Color and Shape:SolidMolecular weight:547.52FXIIa-IN-1 HCl
CAS:FXIIa-IN-1 HCl is a selective inhibitor of Factor XIIa,and can be used to study thrombosis and inflammation induced by artificial surfaces.Formula:C21H17ClN2O6Purity:99.61%Color and Shape:SoildMolecular weight:428.82Porcine Factor Xa
CAS:PorcineFactor Xa is obtained by activating purified Porcine Factor X using Russells' Viper Venom, after which the venom is removed.Color and Shape:SolidD-Pro-Phe-Arg-Chloromethylketone
CAS:D-Pro-Phe-Arg-Chloromethylketone, an inhibitor of coagulation factor XII and plasma kallikrein, is significant in the regulation of thrombosis and inflammationFormula:C21H31ClN6O3Purity:98%Color and Shape:SolidMolecular weight:450.96FXIa-IN-15
CAS:FXIa-IN-15 (Compound (S)-10h) is an inhibitor of factor XIa (FXIa) and plasma kallikrein (PKa) with IC50 values of 0.38 nM and 59.2 nM, respectively. It exhibits anticoagulant properties by prolonging the 50% activated partial thromboplastin time (aPTT) with an EC1.5X of 0.55 μM.Formula:C32H23ClF3N7O4Color and Shape:SolidMolecular weight:662.02cMCoFx1
CAS:cMCoFx1 is an effective and selective FXIIa cyclic peptide inhibitor. It exhibits high binding affinity for FXIIa (KD: 900 pM) and potent inhibitory activity (Ki: 370 pM). cMCoFx1 effectively suppresses the intrinsic coagulation pathway, demonstrates high stability in serum, and shows no cytotoxicity.Formula:C146H232N52O44S6Color and Shape:SolidMolecular weight:3612.12Methoxycarbonyl-D-Nle-Gly-Arg-pNA
CAS:Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin substrate utilized for coagulation factors IXa (FIXa) and Xa (FXa), as evidenced by studies [1] [2] [3Formula:C22H34N8O7Color and Shape:SolidMolecular weight:522.55Asundexian
CAS:Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa,Formula:C26H21ClF4N6O4Purity:99.89% - 99.90%Color and Shape:SolidMolecular weight:592.93Rat Factor Xa
RatFactor Xa is derived from the activation of purified Rat Factor X using Russells' Viper Venom. Following activation, Russells' Viper Venom is removed.Color and Shape:Odour SolidBoc-Ile-Glu-Gly-Arg-AMC
CAS:Boc-IEGR-AMC: fluorogenic substrate for factor Xa and Halocynthia roretzi acrosin.Formula:C34H50N8O10Purity:98%Color and Shape:White PowderMolecular weight:730.81Lofacimig
Lofacimig is a bispecific antibody of VH-VH-G1(h-CH2-CH3) dimer type that targets FXI/PTA.Color and Shape:Odour LiquidD-Leu-Pro-Arg-Rh110-D-Pro
D-Leu-Pro-Arg-Rh110-D-Pro serves as a substrate for Factor XaI (FXIa) and exhibits binding affinity. This compound is composed of Rhodamine 110 linked to a peptide chain via a cleavable bond. Upon cleavage, the intensity of the fluorophore is enhanced. D-Leu-Pro-Arg-Rh110-D-Pro can be utilized to detect FXIa activity.Formula:C42H51N9O7Molecular weight:793.39115Razaxaban
CAS:Razaxaban (also known as BMS-561389 or DPC 906) is an oral inhibitor of Factor Xa, initially developed for the treatment of thrombosis.Formula:C24H20F4N8O2Color and Shape:SolidMolecular weight:528.46FXIIa-IN-3
FXIIa-IN-3 (Compound 8) is an effective and selective inhibitor of Factor XIIa (FXIIa), with an IC50 of 0.045 μM. It demonstrates significant selectivity over related serine proteases, including FXIa, FXa, and FIXa. FXIIa-IN-3 is suitable for research in thromboembolic diseases.Formula:C14H16N4O6Molecular weight:336.10698D-Leu-Pro-Arg-Rh110-D-Pro acetate
D-Leu-Pro-Arg-Rh110-D-Pro acetate is a substrate for Factor XaI (FXIa) with binding affinity. This compound is formed by linking Rhodamine 110 to a peptide chain via a cleavable bond. The cleavage of this bond enhances the intensity of the fluorophore. D-Leu-Pro-Arg-Rh110-D-Pro acetate can be used to detect FXIa activity.Formula:C42H51N9O7·xC2H4O2Naroparcil
CAS:Naroparcil, an oral thioglycoside, has antithrombotic properties and alters thrombin complex formation.Formula:C19H17NO4S2Purity:99.88% - 99.99%Color and Shape:SolidMolecular weight:387.47Chromozym PK
CAS:Chromozym PK is a chromogenic substrate for factor XII assay.Formula:C33H38N8O6Color and Shape:SolidMolecular weight:642.70Concizumab
CAS:Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that selectively binds to the Kunitz protease inhibitor (KPI) 2 domain of TFPI, thereby blocking thePurity:> 95%Color and Shape:LiquidMolecular weight:145.76 kDaEdoxaban impurity 6
CAS:Edoxaban impurity 6 is a byproduct of the anticoagulant Edoxaban, a potent oral factor Xa inhibitor with Kis of 0.561 nM. Used to prevent stroke.
Formula:C16H22ClN5O3Color and Shape:SolidMolecular weight:367.83Edoxaban Isomer
CAS:Edoxaban Isomer is an impurity of Edoxaban, which is a novel inhibitor of factor Xa.Formula:C24H30ClN7O4SColor and Shape:SolidMolecular weight:548.06FXIIa-IN-4
FXIIa-IN-4 (compound 22) is a potent and selective human FXIIa inhibitor, exhibiting IC50 values of 0.032 μM for FXIIa, 0.30 μM for thrombin, and >50 μM for FXIa. It is utilized in anticoagulant research.Formula:C11H9FN4O3Molecular weight:264.06587Betrixaban-d6
CAS:Betrixaban D6 is a deuterium-labeled Betrixaban. Betrixaban is a selective and orally efficacious FXa inhibitor.Formula:C23H22ClN5O3Purity:98%Color and Shape:SolidMolecular weight:457.95Apixaban 13C,d3
CAS:Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor XaFormula:C25H25N5O4Purity:98%Color and Shape:SolidMolecular weight:463.51Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS:Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl) compound inhibits coagulation factor Xa, useful for thrombotic conditions study.
Formula:C27H28N4O5Purity:99.5%Color and Shape:SolidMolecular weight:488.54Edoxaban hydrochloride
CAS:Edoxaban (DU-176b) HCl: Oral, selective Factor Xa inhibitor, Ki 0.561 nM; prevents thromboembolic disease.Formula:C24H31Cl2N7O4SColor and Shape:SolidMolecular weight:584.52BISMUTH SUBGALLATE
CAS:Bismuth subgallate (Dermatol Puder) is an astringent and antiseptic and is applied to skin diseases such as eczema.Formula:C7H5BiO6Purity:98.7%Color and Shape:White To Yellow CrystalsMolecular weight:394.09Fondaparinux sodium
CAS:Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.Formula:C31H43N3Na10O49S8Purity:98% - >99.99%Color and Shape:SolidMolecular weight:1728.08Apixaban
CAS:Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity.Formula:C25H25N5O4Purity:99.73% - 99.93%Color and Shape:SolidMolecular weight:459.50Edoxaban Tosylate Monohydrate
CAS:Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.Formula:C31H40ClN7O8S2Purity:99.86% - 99.91%Color and Shape:SolidMolecular weight:738.27Enoxaparin sodium
CAS:Enoxaparin, a low-weight heparin approved by FDA for STEMI, enhances antithrombin and prevents clotting by inhibiting factors XIa, IXa, Xa, IIa.Formula:C42H59N3Na4O35S2Purity:98%Color and Shape:SolidMolecular weight:1322Betrixaban hydrochloride(330942-05-7(free base))
Betrixaban hydrochloride(330942-05-7(free base)) (PRT054021 hydrochloride) is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5Formula:C23H23Cl2N5O3Purity:99.54%Color and Shape:SolidMolecular weight:488.36Ref: TM-T4690
1mg48.00€2mg60.00€5mg97.00€10mg154.00€25mg338.00€50mg520.00€100mg748.00€1mL*10mM (DMSO)106.00€Benzamidine hydrochloride
CAS:Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin.Formula:C7H9ClN2Purity:99.25% - 99.97%Color and Shape:White To Off-White PowderMolecular weight:156.614-Chlorophenylurea
CAS:4-Chlorophenylurea (NSC-12971) is a novel orally bioavailable inhibitor of factor Xa.Formula:C7H7ClN2OPurity:98.87%Color and Shape:White Granular / PrillMolecular weight:170.6Darexaban
CAS:Darexaban (YM-150) selectively inhibits Factor Xa, reducing clotting and risk of heart/stroke events.Formula:C27H30N4O4Purity:98.33%Color and Shape:SolidMolecular weight:474.55Ref: TM-T31206
1mg46.00€5mg90.00€10mg137.00€25mg222.00€50mg334.00€100mg485.00€200mg690.00€1mL*10mM (DMSO)96.00€Abelacimab
CAS:NI-0801 (Anti-CXCL10 / IP-1) is a CHO-expressed humanized monoclonal antibody targeting CXCL10/IP-10 for the study of vitiligo and biliary cirrhosis.Purity:94.9% (SDS-PAGE); 99.1% (SEC-HPLC) - 94.9% (SDS-PAGE); 99.1% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.32 kDaEdoxaban-d6
CAS:Edoxaban-d6 is a deuterated compound of Edoxaban. Edoxaban has a CAS number of 480449-70-5. Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.Formula:C24H24D6ClN7O4SColor and Shape:SolidMolecular weight:554.09Betrixaban maleate
CAS:"Betrixaban, a non-vitamin K anticoagulant by Portola, inhibits factor Xa with low hERG affinity, preventing VTE in at-risk adults."
Formula:C27H26ClN5O7Purity:99.46% - 99.86%Color and Shape:SolidMolecular weight:567.98Fitusiran
CAS:Fitusiran (ALN-AT3SC) is a siRNA that targets AT mRNA to reduce AT levels and boost thrombin, aiding hemophilia study.Color and Shape:SolidRivaroxaban-d4
CAS:Rivaroxaban-d4 is a deuterated marker of Rivaroxaban for isotopic tracing.BAY 59-7939 is a potent and selective direct inhibitor of coagulation factor Xa (FXa.Formula:C19H18ClN3O5SPurity:98%Color and Shape:SolidMolecular weight:439.91
