FXR
Farnesoid X Receptor (FXR) is a nuclear receptor that plays a key role in the regulation of bile acid homeostasis, lipid metabolism, and glucose regulation. FXR is a potential therapeutic target for treating liver diseases, metabolic disorders, and cardiovascular diseases. FXR inhibitors can modulate these pathways, offering insights into disease mechanisms and therapeutic strategies. At CymitQuimica, we provide a range of FXR inhibitors to support your research in hepatology, metabolism, and drug development.
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Ursodeoxycholic acid
CAS:128-13-2
Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption.
Formula:
C24H40O4
Purity:
99.74% - ≥95%
Color and Shape:
White - Almost White Solid Powder
Molecular weight:
392.57
Ref: TM-T0700
| 1g | 35.00 € | ||
| 5g | 55.00 € | ||
| 1mL*10mM (DMSO) | 39.00 € |
Estimated delivery in United States, on Thursday 8 May 2025
LY2562175
CAS:1103500-20-4
LY2562175 is an effective and selective FXR agonist (EC50: 193 nM).
Formula:
C28H27Cl2N3O4
Purity:
99.16% - 99.78%
Color and Shape:
Solid
Molecular weight:
540.44
Ref: TM-T15806
| 1mg | 104.00 € | ||
| 5mg | 227.00 € | ||
| 10mg | 369.00 € | ||
| 25mg | 740.00 € | ||
| 50mg | 1,169.00 € | ||
| 100mg | 1,568.00 € | ||
| 200mg | 2,118.00 € | ||
| 1mL*10mM (DMSO) | 269.00 € |
Estimated delivery in United States, on Thursday 8 May 2025
Chenodeoxycholic acid
CAS:474-25-9
Chenodeoxycholic acid (CDCA), a bile acid, usually conjugated with either glycine or taurine, acts as …
Formula:
C24H40O4
Purity:
99.70% - 99.72%
Color and Shape:
White - Almost White Solid Powder
Molecular weight:
392.57
Ref: TM-T0847
| 100mg | 48.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Thursday 8 May 2025
LH10
LH10 is an FXR agonist based on fexaramine, with an EC50 of 0.14 μM. It …
Formula:
C34H33N3O2
Color and Shape:
Solid
Molecular weight:
515.64
Ref: TM-T203523
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 9 May 2025
Osocimab
CAS:2056878-75-0
Osocimab (BAY 1213790) is a strong FXIa inhibitor, Ki 2.4 nM, EC50 0.2 nM, and …
Purity:
> 95% - > 95%
Color and Shape:
Liquid
Molecular weight:
144.46 kDa
Ref: TM-T77124
| 1mg | 235.00 € | ||
| 5mg | 615.00 € | ||
| 10mg | 938.00 € |
Estimated delivery in United States, on Friday 9 May 2025
Tauro-β-muricholic acid sodium
CAS:145022-92-0
Tauro-β-muricholic Acid sodium is a endogenous metabolite, is a competitive and reversible antagonist of farnesoid …
Formula:
C26H44NNaO7S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
537.69
Ref: TM-T13093
| 1mg | To inquire | ||
| 5mg | To inquire | ||
| 500µg | To inquire |
Estimated delivery in United States, on Friday 9 May 2025
Tauro-β-muricholic acid
CAS:25696-60-0
Tauro-β-muricholic acid (TβMCA), a trihydroxylated bile acid, acts as a competitive and reversible FXR antagonist …
Formula:
C26H45NO7S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
515.7
Ref: TM-T81030
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 9 May 2025
FXR agonist 5
CAS:2414008-05-0
FXR agonist 5 is an FXR agonist used in the study of liver diseases or …
Formula:
C40H53N5O5
Purity:
99.74%
Color and Shape:
Liquid
Molecular weight:
683.88
Ref: TM-T75160
| 1mg | 184.00 € | ||
| 5mg | 462.00 € | ||
| 10mg | 749.00 € | ||
| 25mg | 1,499.00 € |
Estimated delivery in United States, on Friday 9 May 2025
FXR agonist 10
FXR agonist10 (Compound 27) acts as an agonist for FXR with an EC50 of 14.26 …
Formula:
C15H22O4
Color and Shape:
Solid
Molecular weight:
266.33
Ref: TM-T203628
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 9 May 2025
FXR agonist 11
CAS:2768502-17-4
FXR agonist11 (Compound 14) is an FXR activator with an EC50 of 1.2 μM and …
Formula:
C18H16N2O5
Color and Shape:
Solid
Molecular weight:
340.33
Ref: TM-T203206
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 9 May 2025
LZ-007
CAS:2920000-23-1
LZ-007 is an agonist of the Farnesoid X receptor (FXR), with an EC50 of 51 …
Formula:
C27H29F3N2O5
Color and Shape:
Solid
Molecular weight:
518.53
Ref: TM-T203062
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 9 May 2025
ZLY28
ZLY28 is a novel, first-in-class compound with specific intestinal restriction and oral activity, serving as …
Formula:
C29H23Cl2NO4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
520.4
Ref: TM-T78910
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Friday 9 May 2025
Chenodeoxycholic Acid sodium salt
CAS:2646-38-0
Chenodeoxycholic Acid sodium salt (CDCA sodium salt) is a bile acid in humans that activates …
Formula:
C24H39NaO4
Purity:
99.68% - 99.72%
Color and Shape:
Liquid
Molecular weight:
414.55
Ref: TM-T65070
| 100mg | 40.00 € | ||
| 500mg | 60.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Tuesday 13 May 2025
NR1H4 Protein, Human, Recombinant (His)
NR1H4 Protein, Human, Recombinant (His) is expressed in E.
Color and Shape:
Lyophilized Powder
Molecular weight:
27.83 kDa (predicted)
Ref: TM-TMPY-06768
| 50µg | 608.00 € | ||
| 500µg | 3,832.00 € |
Estimated delivery in United States, on Tuesday 13 May 2025
NDB
CAS:1660153-08-1
NDB is a hFXRα antagonist that inhibits GW4064-stimulated FXR/RXR interactions in primary mouse hepatocytes.NDB is …
Formula:
C26H28Cl2N2O2
Purity:
98.94%
Color and Shape:
Liquid
Molecular weight:
471.42
Ref: TM-T63042
| 1mg | 98.00 € |
Estimated delivery in United States, on Tuesday 13 May 2025
NR1H4 Protein, Mouse, Recombinant (His)
NR1H4 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. …
Color and Shape:
Lyophilized Powder
Molecular weight:
27.80 kDa (predicted)
Ref: TM-TMPY-06756
| 50µg | 608.00 € | ||
| 500µg | 3,832.00 € |
Estimated delivery in United States, on Tuesday 13 May 2025
Cilofexor
CAS:1418274-28-8
Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.
Formula:
C28H22Cl3N3O5
Purity:
99.32% - ≥95%
Color and Shape:
Solid
Molecular weight:
586.85
Ref: TM-T7436
| 1mg | 50.00 € | ||
| 2mg | 73.00 € | ||
| 5mg | 124.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 380.00 € | ||
| 50mg | 567.00 € | ||
| 100mg | 807.00 € | ||
| 500mg | 1,644.00 € | ||
| 1mL*10mM (DMSO) | 158.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
Vonafexor
CAS:1192171-69-9
Vonafexor (EYP001) is a farnesoid X receptor (FXR, NR1H4) agonist, with anti-HBV effects
Formula:
C19H15Cl3N2O5S
Purity:
98.74%
Color and Shape:
Solid
Molecular weight:
489.76
Ref: TM-T8471
| 10mg | 52.00 € | ||
| 25mg | 92.00 € | ||
| 50mg | 144.00 € | ||
| 100mg | 235.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
GW 4064
CAS:278779-30-9
GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).
Formula:
C28H22Cl3NO4
Purity:
97.47% - 99.94%
Color and Shape:
Solid
Molecular weight:
542.84
Ref: TM-T2233
| 5mg | 50.00 € | ||
| 10mg | 84.00 € | ||
| 25mg | 139.00 € | ||
| 50mg | 235.00 € | ||
| 100mg | 424.00 € | ||
| 200mg | 640.00 € | ||
| 500mg | 1,008.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
Tauro-Obeticholic acid
CAS:863239-61-6
Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist …
Formula:
C28H49NO6S
Purity:
99.82% - 99.82%
Color and Shape:
Solid
Molecular weight:
527.76
Ref: TM-T13092
| 1mg | 117.00 € | ||
| 5mg | 274.00 € | ||
| 10mg | 414.00 € | ||
| 25mg | 685.00 € | ||
| 50mg | 938.00 € | ||
| 100mg | 1,311.00 € | ||
| 1mL*10mM (DMSO) | 349.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
