Phospholipase
Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic substances, playing a critical role in membrane biology and the generation of signaling molecules. Inhibitors of phospholipases are used to study their role in inflammatory diseases, cardiovascular disorders, and neurodegeneration. These inhibitors are also valuable in exploring lipid signaling pathways and their implications in disease mechanisms. At CymitQuimica, we provide a variety of phospholipase inhibitors to support your research in inflammation, lipid metabolism, and cell signaling.
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Lp-PLA2-IN-1
CAS:1420367-28-7
Lp-PLA2-IN-1 suppresses Lp-PLA2, aiding in treating atherosclerosis and Alzheimer's.
Formula:
C21H17F5N4O3
Purity:
99.25%
Color and Shape:
Solid
Molecular weight:
468.38
Ref: TM-T15782
| 1mg | 40.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 205.00 € | ||
| 50mg | 310.00 € | ||
| 100mg | 432.00 € | ||
| 200mg | 580.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
Omeprazole
CAS:73590-58-6
Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral …
Formula:
C17H19N3O3S
Purity:
97.61%
Color and Shape:
White Solid
Molecular weight:
345.42
Ref: TM-T0757
| 50mg | 47.00 € | ||
| 100mg | 52.00 € | ||
| 200mg | 68.00 € | ||
| 500mg | 94.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
Tris(2,4-di-tert-butylphenyl)phosphate
CAS:95906-11-9
Tris(2,4-di-tert-butylphenyl)phosphate (TDTBPP) inhibits secretory phospholipase A2 (sPLA2) with anti-inflammatory effect. Cost-effective and quality-assured.
Formula:
C42H63O4P
Purity:
100%
Color and Shape:
Solid
Molecular weight:
662.92
Ref: TM-T13206
| 10mg | 35.00 € | ||
| 25mg | 49.00 € | ||
| 50mg | 66.00 € | ||
| 100mg | 96.00 € | ||
| 500mg | 203.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
ML349
CAS:890819-86-0
ML349 is an inhibitor of LYPLA2 (IC50: 144 nM). ML349 is an effective and specific …
Formula:
C23H22N2O4S2
Purity:
99.59% - 99.82%
Color and Shape:
Solid
Molecular weight:
454.56
Ref: TM-T16108
| 1mg | 35.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 107.00 € | ||
| 25mg | 226.00 € | ||
| 50mg | 363.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
Lansoprazole
CAS:103577-45-3
Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the …
Formula:
C16H14F3N3O2S
Purity:
99.19% - 99.84%
Color and Shape:
White Crystalline Powder
Molecular weight:
369.36
Ref: TM-T0674
| 1g | 72.00 € | ||
| 500mg | 54.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
Indomethacin
CAS:53-86-1
Indomethacin (Indomethacin) is a inhibitor of COX1 and COX2. Indomethacin is a non-steroidal anti-inflammatory agent. …
Formula:
C19H16ClNO4
Purity:
99.27% - 99.84%
Color and Shape:
Pale-Yellow To Yellow-Tan Crystalline Powder Physical Description Crystals (Ntp 1992)
Molecular weight:
357.79
Ref: TM-T0458
| 1g | 59.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
VU0359595
CAS:1246303-14-9
VU0359595 (ML-270) is a selective PLD1 inhibitor with 3.7 nM IC50; >1700x more selective over …
Formula:
C25H29BrN4O2
Purity:
99.15%
Color and Shape:
Solid
Molecular weight:
497.43
Ref: TM-T21777
| 1mg | 87.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 291.00 € | ||
| 25mg | 500.00 € | ||
| 50mg | 730.00 € | ||
| 100mg | 993.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
VU533
CAS:923417-09-8
VU533 is a NAPE-PLD activator, EC50=0.30 µM, boosts macrophage activity, potential in cardiometabolic diseases.
Formula:
C21H22FN3O3S2
Purity:
99.08%
Color and Shape:
Liquid
Molecular weight:
447.55
Ref: TM-T77616
| 1mg | 50.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 500.00 € | ||
| 100mg | 714.00 € | ||
| 500mg | 1,439.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
A3373
A3373 is a novel inhibitor targeting both Phospholipase D1 (PLD1) and Phospholipase D2 (PLD2), demonstrating …
Purity:
98%
Ref: TM-T83226
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
SB-435495
CAS:304694-39-1
SB-435495 is a compound characterized by its potent, selective, reversible, and non-covalent inhibition of Lp-PLA2, …
Formula:
C38H40F4N6O2S
Purity:
≥98%
Color and Shape:
Liquid
Molecular weight:
720.82
Ref: TM-T75255
| 1mg | 57.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 121.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 430.00 € | ||
| 50mg | 703.00 € | ||
| 100mg | 1,114.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
AACOCF3
CAS:149301-79-1
AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid.
Formula:
C21H31F3O
Purity:
99% - 99%
Color and Shape:
Yellow Liquid
Molecular weight:
356.47
Ref: TM-T21681
| 1mg | 75.00 € | ||
| 5mg | 142.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Compound 48/80 trihydrochloride
CAS:848035-21-2
C48/80 trihydrochloride: a mixture that triggers mast cell degranulation and histamine release, inhibiting PI-PLC in …
Formula:
C32H48Cl3N3O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
629.1
Ref: TM-T13623
| 1mg | 41.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
nSMase2-IN-1
nSMase2-IN-1 is an orally active inhibitor of Neutral sphingomyelinase 2 (nSMase2) with a potent IC50 …
Formula:
C12H17N5O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
247.3
Ref: TM-T79321
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
DPTIP
CAS:351353-48-5
DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 …
Formula:
C21H18N2O3S
Purity:
98.80%
Color and Shape:
Liquid
Molecular weight:
378.44
Ref: TM-T60043
| 1mg | 48.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 291.00 € | ||
| 50mg | 479.00 € | ||
| 100mg | 694.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Fuzapladib
CAS:141283-87-6
Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.
Formula:
C15H20F3N3O3S
Purity:
99.65%
Color and Shape:
Soild
Molecular weight:
379.4
Ref: TM-T67749
| 1mg | 63.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 208.00 € | ||
| 25mg | 440.00 € | ||
| 50mg | 638.00 € | ||
| 100mg | 828.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
BIRM 271
CAS:149106-77-4
BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating …
Formula:
C21H25N3O
Purity:
99.38%
Color and Shape:
Soild
Molecular weight:
335.44
Ref: TM-T77638
| 1mg | 182.00 € | ||
| 5mg | 399.00 € | ||
| 10mg | 591.00 € | ||
| 25mg | 922.00 € | ||
| 50mg | 1,263.00 € | ||
| 100mg | 1,710.00 € | ||
| 500mg | 3,418.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
A4333
A4333, a biotinylated derivative of A3373, selectively inhibits Phospholipase D1 (PLD1) while sparing PLD2.
Purity:
98%
Ref: TM-T83225
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
CCR1/5/8 activator 1
CAS:4771-50-0
CCR1/5/8 activator 1 is a cytoplasmic phospholipase A inhibitor with antifungal activity.
Formula:
C10H9NO
Purity:
100%
Color and Shape:
Liquid
Molecular weight:
159.18
Ref: TM-T77349
| 5mg | 41.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 80.00 € | ||
| 50mg | 102.00 € | ||
| 100mg | 150.00 € | ||
| 500mg | 361.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
LEI110
CAS:2313525-90-3
LEI110 inhibits PLA2G16 and HRASLS enzymes, Ki 20 nM, selectively targets related thiol hydrolases.
Formula:
C25H23F3N2O3
Purity:
97.56% - 98.8%
Color and Shape:
Liquid
Molecular weight:
456.46
Ref: TM-T9753
| 1mg | 94.00 € | ||
| 5mg | 198.00 € | ||
| 10mg | 293.00 € | ||
| 25mg | 497.00 € | ||
| 50mg | 716.00 € | ||
| 1mL*10mM (DMSO) | 201.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Bromoenol lactone
CAS:88070-98-8
Bromoenol lactone ((6E)-Bromoenol lactone) is an iPLA2尾 and serine protease inhibitor that attenuates nicotine-induced breast …
Formula:
C16H13BrO2
Color and Shape:
Solid
Molecular weight:
317.18
Ref: TM-T14829
| 1mg | 46.00 € | ||
| 2mg | To inquire | ||
| 5mg | 89.00 € | ||
| 10mg | 138.00 € | ||
| 1mL*10mM (DMSO) | 159.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
