Phospholipase
Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic substances, playing a critical role in membrane biology and the generation of signaling molecules. Inhibitors of phospholipases are used to study their role in inflammatory diseases, cardiovascular disorders, and neurodegeneration. These inhibitors are also valuable in exploring lipid signaling pathways and their implications in disease mechanisms. At CymitQuimica, we provide a variety of phospholipase inhibitors to support your research in inflammation, lipid metabolism, and cell signaling.
Found 82 products of "Phospholipase"
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Omeprazole
CAS:<p>Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.</p>Formula:C17H19N3O3SPurity:98.43% - 98.48%Color and Shape:White SolidMolecular weight:345.42ML349
CAS:<p>ML349 is an inhibitor of LYPLA2 (IC50: 144 nM). ML349 is an effective and specific acyl protein thioesterase 2 (APT-2) inhibitor (Ki: 120 nM).</p>Formula:C23H22N2O4S2Purity:99.59% - 99.88%Color and Shape:SolidMolecular weight:454.56Tris(2,4-di-tert-butylphenyl)phosphate
CAS:<p>Tris(2,4-di-tert-butylphenyl)phosphate (TDTBPP) inhibits secretory phospholipase A2 (sPLA2) with anti-inflammatory effect. Cost-effective and quality-assured.</p>Formula:C42H63O4PPurity:99.73%Color and Shape:SolidMolecular weight:662.92Lp-PLA2-IN-1
CAS:<p>Lp-PLA2-IN-1 suppresses Lp-PLA2, aiding in treating atherosclerosis and Alzheimer's.</p>Formula:C21H17F5N4O3Purity:99.60%Color and Shape:SolidMolecular weight:468.38Lansoprazole
CAS:<p>Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON</p>Formula:C16H14F3N3O2SPurity:99.18% - 99.84%Color and Shape:White Crystalline PowderMolecular weight:369.36Niflumic acid
CAS:<p>Niflumic acid (Nifluril) is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis.</p>Formula:C13H9F3N2O2Purity:99.47%Color and Shape:SolidMolecular weight:282.22nSMase2-IN-1
<p>nSMase2-IN-1 is an orally active inhibitor of Neutral sphingomyelinase 2 (nSMase2) with a potent IC50 value of 0.13 ± 0.06 μM.</p>Formula:C12H17N5OPurity:98%Color and Shape:SolidMolecular weight:247.3DPTIP hydrochloride
CAS:<p>DPTIP hydrochloride is a potent inhibitor of neutral sphingomyelinase (N-SMase 2) that can cross the blood-brain barrier. It acts as an exosome inhibitor with an IC50 value of 30 nM.</p>Formula:C21H19ClN2O3SColor and Shape:SolidMolecular weight:414.91A3373
CAS:<p>A3373 is a novel inhibitor targeting both Phospholipase D1 (PLD1) and Phospholipase D2 (PLD2), demonstrating half maximal inhibitory concentrations (IC50) of</p>Formula:C17H9F7N2OPurity:98%Color and Shape:SoildMolecular weight:390.26BIRM 271
CAS:<p>BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils.</p>Formula:C21H25N3OPurity:99.64%Color and Shape:SoildMolecular weight:335.44AACOCF3
CAS:<p>AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid.</p>Formula:C21H31F3OPurity:99% - 99%Color and Shape:Yellow LiquidMolecular weight:356.47Compound 48/80 trihydrochloride
CAS:<p>Compound 48/80 trihydrochloride (C48/80 trihydrochloride) 是 N-甲基对甲氧基苯乙胺和甲醛发生缩合反应后的混合物。Compound 48/80 trihydrochloride 是一种肥大细胞 (mast cell) 脱颗粒剂和组胺 (histamine) 释放剂。Compound 48/80 trihydrochloride 对人血小板磷脂酰肌醇特异性磷脂酶 C (phosphatidylinositol-specific phospholipase C) 活性有抑制作用。</p>Formula:C32H48Cl3N3O3Purity:98%Color and Shape:SolidMolecular weight:629.11-Myristoyl-2-Linoleoyl-sn-glycero-3-PC
CAS:<p>1-Myristoyl-2-Linoleoyl-sn-glycero-3-PC is a phospholipid identified in human plasma, characterized by the presence of Myristic acid and Linoleic acid at the sn-1 and sn-2 positions, respectively.</p>Formula:C40H76NO8PColor and Shape:SolidMolecular weight:730.01A4333
<p>A4333, a biotinylated derivative of A3373, selectively inhibits Phospholipase D1 (PLD1) while sparing PLD2.</p>Purity:98%Color and Shape:Odour SolidDPTIP
CAS:<p>DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM.</p>Formula:C21H18N2O3SPurity:99.88%Color and Shape:SolidMolecular weight:378.44PLA2-IN-1
<p>PLA2-IN-1 (Compound 7) is a potent and selective inhibitor of phospholipase A (PLA2) with an IC50 value of 1 nM. It effectively inhibits PLA2-induced coagulation disorders in vitro and shows potential for use as an antidote for snake bites caused by cobra venom.</p>Color and Shape:Odour SolidVU533
CAS:<p>VU533 is a NAPE-PLD activator, EC50=0.30 µM, boosts macrophage activity, potential in cardiometabolic diseases.</p>Formula:C21H22FN3O3S2Purity:99.08%Color and Shape:SolidMolecular weight:447.55LEI110
CAS:<p>LEI110 inhibits PLA2G16 and HRASLS enzymes, Ki 20 nM, selectively targets related thiol hydrolases.</p>Formula:C25H23F3N2O3Purity:98.66% - 98.8%Color and Shape:SolidMolecular weight:456.46ASM-IN-3
CAS:<p>ASM-IN-3 (Compound 21b) is a selective acid sphingomyelinase (ASM) inhibitor that can penetrate the blood-brain barrier, with an IC50 of 3.37 μM against purified human ASM. By inhibiting ASM activity in the hippocampus and promoting neurogenesis, ASM-IN-3 alleviates depressive-like behavior in reserpine-induced depressive rats.</p>Formula:C17H13ClN2O4Color and Shape:SolidMolecular weight:344.75SB-435495
CAS:<p>SB-435495 is a compound characterized by its potent, selective, reversible, and non-covalent inhibition of Lp-PLA2, demonstrating an IC50 value of 0.06 nM.</p>Formula:C38H40F4N6O2SPurity:99.07%Color and Shape:SolidMolecular weight:720.82
