Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(1,025 products)
- ACK(1 products)
- AChR(647 products)
- ATP Citrate Lyase(17 products)
- Adrenergic Receptor(3,023 products)
- BACE(37 products)
- Beta Amyloid(230 products)
- CaMK(73 products)
- Cyclooxygenase (COX) Inhibitors(602 products)
- Dopamine Receptor(445 products)
- GABA Receptor(373 products)
- Gamma-secretase(62 products)
- GluR(265 products)
- GlyT(26 products)
- Histamine Receptor(385 products)
- LRRK2(43 products)
- Melatonin Receptor(26 products)
- NMDAR(10 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
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Found 5637 products of "Neuroscience"
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AChE/BuChE-IN-1
CAS:AChE/BuChE-IN-1: BuChE inhibitor (IC50=0.48µM), weaker AChE blocker (IC50=7.16µM), ·OH scavenger (IC50=0.1674µM), may aid in AD research.Formula:C19H19NO4Color and Shape:SolidMolecular weight:325.36Pralidoxime
CAS:Pralidoxime reactivates AChE blocked by nerve agents, aiding as an organophosphate poisoning antidote.Formula:C7H9N2OColor and Shape:SolidMolecular weight:137.16Ph-HTBA
CAS:Ph-HTBA: high-affinity CaMKIIα modulator, brain-penetrant, Kd 757 nM, used in ischemia/neurodegeneration research.Formula:C19H18O3Color and Shape:SolidMolecular weight:294.34VU 0360172 hydrochloride
CAS:positive allosteric modulator of mGlu5 receptorsFormula:C18H16ClFN2OPurity:98%Color and Shape:SolidMolecular weight:330.78VU0463841
CAS:VU0463841 is a mGlu5 negative allosteric modulators.
Formula:C13H8ClFN4OColor and Shape:SolidMolecular weight:290.68Flupyrimin
CAS:Flupyrimin is the insect nicotinic acetylcholine receptor (nAChR) antagonist [1].Formula:C13H9ClF3N3OColor and Shape:SolidMolecular weight:315.68ZK93423
CAS:ZK93423: potent benzodiazepine agonist, IC50=1nM, non-selective, Ki=4.1-6nM for α1-α5 GABAA subunits.Formula:C23H22N2O4Color and Shape:SolidMolecular weight:390.43CP 135807
CAS:CP 135807 is a 5-HT1D receptor agonist.Formula:C19H21N5O2Purity:98%Color and Shape:SolidMolecular weight:351.4AFDX384
CAS:AFDX384 is potent M2/M4 selective antagonist.Formula:C28H42N6O5SColor and Shape:SolidMolecular weight:574.74VU6010572
CAS:VU6010572: potent, selective mGlu3 modulator, IC50 245 nM, high CNS penetration.Formula:C20H18FNO3Color and Shape:SolidMolecular weight:339.36Bisindolylmaleimide VII
CAS:Bisindolylmaleimide VII is a selective inhibitor of protein kinase C.Formula:C27H27N5O2Color and Shape:SolidMolecular weight:453.54AChE-IN-12
CAS:AChE-IN-12 inhibited rat/eel AChE, crossed BBB, prevented Aβ1-42 aggregation, and has potential for Alzheimer's research.Formula:C33H41NO7Color and Shape:SolidMolecular weight:563.68CGS 12066B dimaleate
CAS:5-HT1B full agonistFormula:C25H25F3N4O8Purity:98%Color and Shape:SolidMolecular weight:566.48RX 801077
CAS:RX 801077 is a selective I2R agonist, Ki of 70.1 nM, with anti-inflammatory and neuroprotective properties for TBI research.Formula:C11H10N2OColor and Shape:SolidMolecular weight:186.21Prucalopride hydrochloride
CAS:Prucalopride hydrochloride is a selective agonist of the 5-HT4.Formula:C18H27Cl2N3O3Purity:98%Color and Shape:SolidMolecular weight:404.33ZM 169369
CAS:ICI 169369, a 5-HT2/5-HT1C antagonist, can evoke endothelium-dependent relaxation in rabbit aorta.Formula:C19H20N2SColor and Shape:SolidMolecular weight:308.44Cycrimine
CAS:Cycrimine: oral M1 mAChR blocker, lowers acetylcholine, antispasmodic, for Parkinson's and mental disorder studies.Formula:C19H29NOColor and Shape:SolidMolecular weight:287.44Ro 64-5229
CAS:mGlu2 antagonistFormula:C17H19Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:352.26FR260010
CAS:FR260010 is a novel potent serotonin 5-HT2C receptor antagonist.Formula:C22H19N5Color and Shape:SolidMolecular weight:353.42γ-Secretase modulator 11
CAS:5-{8-[(3,4'-Difluoro[1,1'-biphenyl]-4-yl)methoxy]-2-methylimidazo[1,2-a]pyridin-3-yl}-N-methylpyridine-2-carboxamide (1o) exhibited high in vitro potency andFormula:C28H22F2N4O2Color and Shape:SolidMolecular weight:484.5PCS1055 dihydrochloride
CAS:PCS1055 is a selective M4 antagonist (IC50: 18.1 nM, Ki: 6.5 nM) and potent AChE inhibitor with >100-fold M1/M3/M5 selectivity.Formula:C27H34Cl2N4Purity:98%Color and Shape:SolidMolecular weight:485.49AChE/BChE-IN-8
CAS:AChE/BChE-IN-8 inhibits AChE (Ki=0.788 μM) & BChE (Ki=2.364 μM), crosses the blood-brain barrier, and is low in cytotoxicity.Formula:C26H32N2O2Color and Shape:SolidMolecular weight:404.549-CP-Ade Mesylate
CAS:9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase.Formula:C11H17N5O3SPurity:99.81%Color and Shape:SolidMolecular weight:299.35(±)-Muscarine chloride
CAS:(±)-Muscarine chloride is the racemate of Muscarine chloride. Muscarine is a prototypical agonist for the muscarinic acetylcholine receptor [1] [2].Formula:C9H20ClNO2Color and Shape:SolidMolecular weight:209.71BuChE-IN-1
CAS:BuChE-IN-1 is a potent BBB-permeable, low-toxic BuChE inhibitor with potential for AD research.Formula:C23H23FN2O4SColor and Shape:SolidMolecular weight:442.5NNC052090
CAS:NNC052090 inhibits GABA uptake, favoring hBGT-1 (Ki=1.4μM), affects α1/D2 receptors (IC50=266/1632nM).Formula:C27H30N2O2Color and Shape:SolidMolecular weight:414.54γ-Secretase modulator 12
CAS:γ-Secretase modulator 12 (Compound 1a) is a selective compound that effectively reduces amyloid-β42 (Aβ42) levels with an IC50 of 0.39 μM.Formula:C25H23N3O2Color and Shape:SolidMolecular weight:397.47SSAO inhibitor-2
CAS:SSAO inhibitor-2 targets human SSAO (<10 nM) and MAO-A (10-100 μM); useful in various diseases research.Formula:C14H21FN4O2Color and Shape:SolidMolecular weight:296.34AChE/BChE-IN-5
CAS:AChE/BChE-IN-5 (BMC-16) crosses BBB; IC50: hAChE 266 nM, hBChE 10.6 nM. Dual AChE/BChE inhibitor.Formula:C17H26N2O3Color and Shape:SolidMolecular weight:306.4CBP501
CAS:CBP501 peptide inhibits kinases like MAPKAP-K2/C-Tak1/CHK1, preventing Cdc25C function and blocking the entry into mitosis.Formula:C86H122F5N29O17Color and Shape:SolidMolecular weight:1929.06DREADD agonist 21 dihydrochloride
CAS:DREADD agonist 21 dihydrochloride is a potent human muscarinic acetylcholine M3 receptors ( hM3Dq ) agonist with EC 50 of 1.7 nM [1].Formula:C17H20Cl2N4Purity:98%Color and Shape:SolidMolecular weight:351.27AChE/MAO-B-IN-3
AChE/MAO-B-IN-3: dual inhibitor for AChE (IC50 = 0.0257 µM) and MAO-B (IC50 = 0.0456 µM), researched for Alzheimer's.Formula:C24H28N2O4Color and Shape:SolidMolecular weight:408.49S-15535
CAS:S-15535 is a potent, orally active, partial 5-HT1A receptor agonist.Formula:C21H24N2O2Purity:98%Color and Shape:SolidMolecular weight:336.43OSU 6162 hydrochloride
CAS:Dopamine stabilizerFormula:C15H24ClNO2SPurity:98%Color and Shape:SolidMolecular weight:317.88MK-212
CAS:MK-212 is a 5HT2C agonist; boosts corticosterone and lowers activity at 0.5-1mg/kg; reduces anxiety without affecting movement at 0.1-0.2mg/kg in mice.Formula:C8H11ClN4Color and Shape:SolidMolecular weight:198.65Mazaticol
CAS:Mazaticol: an anticholinergic, blocks muscarinic receptors, inhibits dopamine uptake, used in Parkinson's research.Formula:C21H27NO3S2Color and Shape:SolidMolecular weight:405.57Sultroponium
CAS:Sultroponium may be used as an anticholinergic agent or antispasmodic.Formula:C20H29NO6SColor and Shape:SolidMolecular weight:411.51PF-06371900
CAS:PF-06371900 is a potent and highly selective inhibitor of leucine-rich repeat kinase 2 (LRRK2).Formula:C17H16N6O2SColor and Shape:SolidMolecular weight:368.41Bopindolol
CAS:Bopindolol: oral β1/β2-ARs antagonist and partial agonist; prodrug of pindolol for hypertension research.Formula:C23H28N2O3Color and Shape:SolidMolecular weight:380.48Edivoxetine hydrochloride
CAS:Edivoxetine HCl, a potent NERI, treats depression and ADHD.Formula:C18H27ClFNO4Color and Shape:SolidMolecular weight:375.87J 104129 fumarate
CAS:M3 muscarinic receptor antagonistFormula:C24H36N2O2Purity:98%Color and Shape:SolidMolecular weight:384.55Befloxatone
CAS:Befloxatone is a potent, selective and reversible inhibitor of monoamine oxidase A.Formula:C15H18F3NO5Color and Shape:SolidMolecular weight:349.3SD-6
CAS:SD-6, oral hAChE/hBChE inhibitor (IC50: 0.907/1.579 µM), crosses BBB, non-toxic, for Alzheimer's research.Formula:C20H22N4OSColor and Shape:SolidMolecular weight:366.48AChE/BChE/MAO-B-IN-4
AChE/BChE/MAO-B-IN-4 inhibits MAO-B (IC50: 0.0393 µM), AChE (IC50: 0.0458 µM), BChE (IC50: 0.075 µM), and fights AD with antioxidant action.Formula:C26H33N3O4Color and Shape:SolidMolecular weight:451.56Ambenonium dichloride
CAS:AChE inhibitorFormula:C28H42Cl3N4O2Purity:98%Color and Shape:SolidMolecular weight:573.02RS 23597-190 hydrochloride
CAS:RS 23597-190 hydrochloride is a 5-HT4 receptor antagonist.Formula:C16H24Cl2N2O3Purity:98%Color and Shape:SolidMolecular weight:363.28AChE/BChE-IN-4
CAS:AChE/BChE-IN-4 (BMC-3) crosses the BBB; IC50: hAChE 792 nM, hBChE 2.2 nM. Dual AChE/BChE inhibitor.Formula:C17H26N2O3Color and Shape:SolidMolecular weight:306.4MRK-623
CAS:MRK-623 (14k) is an oral GABA A agonist with high affinity for α1/α2/α3/α5 subunits and anxiolytic properties.Formula:C20H17FN4OColor and Shape:SolidMolecular weight:348.37RJR-2403 oxalate
CAS:RJR-2403 oxalate is a highly selective agonist of α4β2 subtype nicotinic receptor.Formula:C14H18N2O4Purity:98%Color and Shape:SolidMolecular weight:278.308RO5488608
CAS:RO5488608 is a new type of high-efficiency mGlu2/3 NAM.Formula:C23H17F3N2O4SColor and Shape:SolidMolecular weight:474.45Aβ-IN-5
CAS:Aβ-IN-5 (Compound e12) is an orally active Aβ aggregation inhibitor that also inhibits AChE and BuChE with IC50 values of 21.29 μM and 1.32 μM, respectively.Formula:C21H20N2O3Color and Shape:SolidMolecular weight:348.4A 841720
CAS:Potent, selective mGlu1 antagonist A-841720; IC50: 10 nM; 34x selectivity vs mGlu5; analgesic potential.Formula:C17H21N5OSColor and Shape:SolidMolecular weight:343.45BChE-IN-11
CAS:BChE-IN-11: potent, selective, non-competitive BChE inhibitor; IC50=2.1μM; used in AD research.Formula:C22H18O4Color and Shape:SolidMolecular weight:346.38NPEC-caged-LY379268
CAS:NPEC-caged-LY379268 is a type II mGluR agonist [1].Formula:C16H16N2O9Color and Shape:SolidMolecular weight:380.31sEH inhibitor-5
CAS:sEH inhibitor-5 is a potent inhibitor of sEH (soluble epoxide hydrolase) (IC50: 0.1 nM).Formula:C27H26Cl2N6O3SColor and Shape:SolidMolecular weight:585.5Yhhu-3792
CAS:Yhhu-3792 activates Notch, boosts Hes3/Hes5, enhances NSC renewal, expands NSC pool, and may improve memory.Formula:C24H24N4O2Color and Shape:SolidMolecular weight:400.47GABAA receptor agent 7
CAS:Compound 5c, a GABAA receptor modulator with anticonvulsant properties and low neurotoxicity, is promising for epilepsy research.Formula:C18H13ClN4OColor and Shape:SolidMolecular weight:336.77PHCCC(4Me)
CAS:THCCC, a PHCCC analog, is a dual metabotropic glutamate receptor 2/3 negative/positive allosteric modulator.Formula:C18H16N2O3Color and Shape:SolidMolecular weight:308.33IEM 1925 dihydrobromide
CAS:AMPA receptor antagonistFormula:C17H30Br2N2Purity:98%Color and Shape:SolidMolecular weight:422.24BChE-IN-7
CAS:BChE-IN-7 inhibits AChE/BChE selectively and reversibly; IC50 for BChE: 0.06 μM; crosses blood-brain barrier, protects neurons from Aβ toxicity.Formula:C21H24N2O2Color and Shape:SolidMolecular weight:336.43Ambutonium bromide
CAS:Ambutonium bromide is an antagonist of acetylcholine.Formula:C20H27BrN2OPurity:98%Color and Shape:SolidMolecular weight:391.35Caroxazone
CAS:Caroxazone is an antidepressant drug, monoamine oxidase inhibitor (MAOI) that is irreversible and nonselective meanwhile.Formula:C10H10N2O3Color and Shape:SolidMolecular weight:206.2(R)-Oxybutynin
CAS:(R)-Oxybutynin: oral muscarinic blocker with antispasmodic effects, used in neurogenic bladder research.Formula:C22H31NO3Color and Shape:SolidMolecular weight:357.49MAO-B-IN-12
CAS:MAO-B-IN-12 (16c) is a potent MAO-B inhibitor with an IC50 of 1.3 μM and has neuroprotective properties.Formula:C22H30O4Color and Shape:SolidMolecular weight:358.47LY314228
CAS:LY314228 is an antagonist of 5-HT2A receptor.Formula:C20H24N4O3Color and Shape:SolidMolecular weight:368.43Dihydro Donepezil
CAS:Dihydro Donepezil (Dihydro E2020), a Donepezil metabolite, is a potent AChE inhibitor (IC50: hAChE 11.6 nM, bAChE 8.12 nM).Formula:C24H31NO3Color and Shape:SolidMolecular weight:381.51NAP-1
CAS:NAP-1 is an anesthetic that enhances CA1 brain inhibition in rats and causes tadpole sedation (EC50 = 0.53 μM).Formula:C20H18ClNO2Color and Shape:SolidMolecular weight:339.82FG-5893
CAS:FG-5893 is a 5-HT1A agonist and 5-HT2 antagonist with potential anxiolytic activity.Formula:C27H29F2N3O2Purity:98%Color and Shape:SolidMolecular weight:465.53Trimedoxime bromide
CAS:Trimedoxime bromide is a cholinesterase reactivator used as an antidote in alkyl phosphate poisoning.Formula:C15H18Br2N4O2Color and Shape:SolidMolecular weight:446.14Lidanserin
CAS:Lidanserin is an antagonist of the 5-HT2A and α1-adrenergic receptor.Formula:C26H31FN2O4Purity:98%Color and Shape:SolidMolecular weight:454.53BACE1/2-IN-1
CAS:BACE1/2-IN-1 inhibits BACE1/2 with IC50s of 0.01μM/0.0053μM, has better permeability and lower Pgp efflux but reduced metabolic stability.Formula:C21H31N5OSColor and Shape:SolidMolecular weight:401.57TMPH hydrochloride
CAS:neuronal nicotinic ACh receptors (nAChRs) antagonistFormula:C16H32ClNO2Purity:98%Color and Shape:SolidMolecular weight:305.88Hexafluronium Bromide
CAS:Hexafluronium bromide enhances muscle relaxation in surgery by blocking acetylcholine receptors.Formula:C36H42BrN2Color and Shape:SolidMolecular weight:582.649Rivanicline oxalate
CAS:Rivanicline oxalate is an agonist of neuronal nicotinic receptor, showing high selectivity for the α4β2 subtype (Ki=26 nM).Formula:C12H16N2O4Purity:98%Color and Shape:SolidMolecular weight:252.27ENS-163 phosphate
CAS:Ens-163 phosphate is a muscarinic M1 receptor agonist. It is selective.Formula:C11H19N2O5PSPurity:98%Color and Shape:SolidMolecular weight:322.32AChE/BChE/BACE-1-IN-1
CAS:Compound 4k is an oral AChE, BChE, BACE-1 inhibitor with IC50s: 0.058, 0.082, 0.115 μM, crosses blood-brain barrier, and has neuroprotective effects.Formula:C19H21F3N2OColor and Shape:SolidMolecular weight:350.38S 14063
CAS:S 14063 is a potent 5-HT1A receptor antagonist devoid of beta-adrenoceptor blocking properties.Formula:C22H29Cl2N3O2SColor and Shape:SolidMolecular weight:470.45Org-25935
CAS:Org-25935, a GlyT-1 inhibitor, is used potentially for the treatment of schizophrenia and alcohol dependence.Formula:C21H26ClNO3Color and Shape:SolidMolecular weight:375.89Ro4491533
CAS:Ro4491533 is a potent and selective negative allosteric modulator for group II of the metabotropic glutamate receptors (mGluR2/3).Formula:C24H20F3N3OColor and Shape:SolidMolecular weight:423.43MAO-B ligand-1
CAS:MAO-B ligand-1 is a selective MAO-B inhibitor.Formula:C19H19N5O4SColor and Shape:SolidMolecular weight:413.45(RS)-4-Carboxy-3-hydroxyphenylglycine
CAS:broad spectrum EAA agonist/antagonistFormula:C9H9NO5Purity:98%Color and Shape:SolidMolecular weight:211.17sEH/AChE-IN-1
CAS:Compound 12a is a dual sEH/AChE inhibitor with potential for treating Alzheimer's-related neuroinflammation and memory loss.Formula:C29H31ClF3N5O3Color and Shape:SolidMolecular weight:590.04Phenglutarimid
CAS:Phenglutarimid is an anticholinergic. It is used as an antiparkinsonian agent.Formula:C17H24N2O2Purity:98%Color and Shape:SolidMolecular weight:288.38SEN-1269
CAS:SEN-1269 prevents amyloid-β aggregation, shields neurons, and improves memory by hindering Aβ(1-42)-induced issues.Formula:C18H18N4O2Purity:98%Color and Shape:SolidMolecular weight:322.36Usmarapride
CAS:Usmarapride (SUVN-D4010) is an oral 5-HT4 receptor agonist, crosses BBB, with an EC50 of 44 nM, for Alzheimer's research.Formula:C23H31N5O6Color and Shape:SolidMolecular weight:473.53A-85380 HCl
CAS:A-85380 is an agonist of nicotinic acetylcholine receptor.Formula:C9H14Cl2N2OColor and Shape:SolidMolecular weight:237.13Talsaclidine
CAS:Talsaclidine: full M1 agonist, partial M2/M3 agonist with neuron-stimulating effects.Formula:C10H15NOPurity:98%Color and Shape:SolidMolecular weight:165.23Deramciclane fumarate
CAS:Deramciclane fumarate is a 5-HT(2A/C) antagonist with putative anxiolytic activity.Formula:C24H35NO5Color and Shape:SolidMolecular weight:417.545-HT7 receptor ligand 1
CAS:Compound 5c: 5-HT7 receptor ligand, K i = 8 nM, not hepatotoxic, moderate CYP3A4/CYP2D6 interaction.Formula:C21H23N7Color and Shape:SolidMolecular weight:373.45PXS-4787
CAS:PXS-4787 selectively inhibits LOX with IC50 values: 2 μM (Bovine), 3.2 μM (LOXL1), 0.6 μM (LOXL2), 1.4 μM (LOXL3), 0.2 μM (LOXL4).Formula:C10H12FNO2SColor and Shape:SolidMolecular weight:229.27WAY-361789
CAS:WAY-361789 is an agonist of alpha7 nicotinic acetylcholine receptor.Formula:C22H31N5O3Color and Shape:SolidMolecular weight:413.51VU0400195
CAS:VU0400195 is a oral effective, positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu(4)).Formula:C21H16ClN3O3Purity:98%Color and Shape:SolidMolecular weight:393.82ML337
CAS:ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.Formula:C21H20FNO3Purity:99.83%Color and Shape:SolidMolecular weight:353.39Ref: TM-T23003
100mgTo inquire1mg34.00€5mg60.00€1mL*10mM (DMSO)72.00€10mg92.00€25mg195.00€50mg293.00€Mavoglurant racemate
CAS:Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist. Mavoglurant (racemate) is the racemate of mavoglurant.Formula:C19H23NO3Purity:98%Color and Shape:SolidMolecular weight:313.39Muscarine iodide
CAS:Muscarinic acetylcholine receptor agonistFormula:C9H20INO2Purity:98%Color and Shape:SolidMolecular weight:301.17LY-411575 isomer 1
CAS:LY-411575 isomer 1 is a potent γ-secretase inhibitor. LY-411575 isomer 1 is an isomer of LY411575.Formula:C26H23F2N3O4Purity:98%Color and Shape:SolidMolecular weight:479.48SB357134
CAS:SB357134 is a potent, selective and orally active antagonist of 5-HT6 receptor and shows nootropic effects in animal studies.Formula:C17H18Br2FN3O3SPurity:98%Color and Shape:SolidMolecular weight:523.21M1 ligand 1
CAS:Compound 3b-b: N-desmethyl arecoline derivative, muscarinic M1 ligand, potential PET radiotracer.Formula:C20H21NO2Color and Shape:SolidMolecular weight:307.39DS2
CAS:Positive allosteric modulator of δ-subunit containing GABAA receptorsFormula:C18H12ClN3OSPurity:98%Color and Shape:SolidMolecular weight:353.83L-CCG-l
CAS:group II metabotropic glutamate receptor agonistFormula:C6H9NO4Purity:98%Color and Shape:SolidMolecular weight:159.14
