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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5400 products of "Neuroscience"

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  • Remlifanserin

    CAS:
    <p>Remlifanserin is a potent inverse agonist of the serotonin receptor (5-HT2A).</p>
    Formula:C24H29F2N3O2
    Color and Shape:Solid
    Molecular weight:429.50
  • Nedemelteon

    CAS:
    <p>Nedemelteon is an agonist of the melatonin receptor (melatonin receptor).</p>
    Formula:C15H18N2O2
    Color and Shape:Solid
    Molecular weight:258.32
  • BGT1-IN-1

    CAS:
    <p>BGT1-IN-1 (compound 9) is an effective inhibitor of BGT1, demonstrating IC50 values of 13.9 µM for hBGT1 and 58.3 µM for GAT3. It exhibits no cytotoxic effects and possesses neuroprotective activity.</p>
    Formula:C6H9NO2
    Color and Shape:Solid
    Molecular weight:127.14
  • AChE/BACE1/GSK3β-IN-1


    <p>AChE/BACE1/GSK3β-IN-1 is an orally active, blood-brain barrier-transparent, moderately bioavailable triple inhibitor of AChE/BACE1/GSK3β.</p>
    Formula:C26H27FN2O4
    Color and Shape:Solid
    Molecular weight:450.5
  • ChEs/MAOs-IN-2

    CAS:
    <p>ChEs/MAOs-IN-2 (compound a11) serves as an inhibitor for both cholinesterases and monoamine oxidases, exhibiting IC 50 values of 0.10 µM for MAO-A, 0.20 µM for MAO-B, 0.30 µM for AChE, and 0.40 µM for BChE. This compound shows promise for Alzheimer's disease research [1].</p>
    Formula:C15H12N2O3S
    Color and Shape:Solid
    Molecular weight:300.33
  • SNRI-IN-1

    CAS:
    <p>SNRI-IN-1 (Compound 7a) acts as a dual inhibitor of serotonin and noradrenaline monoamine reuptake, with a P-glycoprotein Efflux Ratio of 20 [1].</p>
    Formula:C16H20Cl2N2O2
    Color and Shape:Solid
    Molecular weight:343.25
  • MAO-A inhibitor 1

    CAS:
    <p>MAO-A Inhibitor 1 (compound VIII) acts as a MAO-A inhibitor and exhibits an IC50 value of 100 μM [1].</p>
    Formula:C14H12O4
    Color and Shape:Solid
    Molecular weight:244.24
  • Dual AChE-MAO B-IN-1


    <p>Dual AChE-MAO B-IN-1: orally active CNS-permeable, safe, stable neuroprotective agent; AChE IC50=550 nM, MAO-B IC50=8.2 nM.</p>
    Formula:C23H25F2NO4
    Color and Shape:Solid
    Molecular weight:417.45
  • AChE-IN-47

    CAS:
    <p>AChE-IN-47 (compound g17) is an acetylcholinesterase (AChE) inhibitor with an IC50 of 0.24 μM. It prevents the self-aggregation of β-amyloid peptides and exhibits neuroprotective properties by effectively reducing the accumulation of intracellular reactive oxygen species (ROS).</p>
    Formula:C20H17F3N4O4S
    Molecular weight:466.43
  • QP5020

    CAS:
    <p>QP5020 is a QPCTL inhibitor with an IC50 value of 15 nM, demonstrating antitumor efficacy.</p>
    Formula:C20H19FN6
    Molecular weight:362.40
  • MAO-B-IN-28

    CAS:
    <p>MAO-B-IN-28 (compound 10e) is a potent hMAO-B inhibitor with an IC50 value of 1.9±0.5 nM, potentially serving as a candidate molecule for neurodegenerative disease research.</p>
    Formula:C19H10F3NO4S
    Molecular weight:405.35
  • CaMKK2-IN-1

    CAS:
    <p>CaMKK2-IN-1 is a selective and potent inhibitor of CaMKK2, exhibiting an IC50 of 7 nM.</p>
    Formula:C22H22N2O3
    Molecular weight:362.42
  • AChE/BChE-IN-19

    CAS:
    <p>AChE/BChE-IN-19 (compound 12) is a nicotinic hydrazine derivative that acts as an inhibitor of AChE (IC50=21.45 nM) and BChE (IC50=18.42 nM), and it is applicable in Alzheimer's disease research.</p>
    Formula:C26H22N4O3
    Molecular weight:438.48
  • BACE1-IN-4

    CAS:
    <p>BACE1-IN-4 is a potent and highly selective BACE1 inhibitor (IC50: 3.8 nM; Ki: 1.9 nM), more selective at BACE1 over BACE2.</p>
    Formula:C21H23F2N5O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:511.57
  • MAO-B-IN-40

    CAS:
    <p>MAO-B-IN-40 (3a) is an inhibitor of MAOB, exhibiting an IC50 value of 0.493 μM against hMAOB, and demonstrates significant neuroprotective and antioxidant effects. MAO-B-IN-40 (3a) is applicable in Parkinson's disease research.</p>
    Formula:C17H15N3O3
    Color and Shape:Solid
    Molecular weight:309.319
  • (9R)-RO7185876

    CAS:
    <p>(9R)-RO7185876 (Compound example 16) is a γ-secretase inhibitor. It reduces the secretion of Αβ42. This compound can be employed in the research of Alzheimer's disease, cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, multi-infarct dementia, senile dementia, or Down syndrome.</p>
    Formula:C25H28F3N7
    Color and Shape:Solid
    Molecular weight:483.532
  • SZ1676

    CAS:
    <p>SZ1676 is a derivative of SZ1677, which is an agent of neuromuscular blocking.</p>
    Formula:C37H59BrN2O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:707.78
  • BPN-15606 besylate


    <p>BPN-15606 besylate is a potent oral γ-secretase regulator reducing Aβ42 and Aβ40 with good pharmacokinetics. IC50: 7 nM (Aβ42), 17 nM (Aβ40).</p>
    Formula:C29H29FN6O4S
    Color and Shape:Solid
    Molecular weight:576.64
  • YM 202074

    CAS:
    <p>metabotropic glutamate receptor type 1 (mGlu1) antagonist</p>
    Formula:C56H72N8O16S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1177.34
  • Beloxepin

    CAS:
    <p>Beloxepin is an oral dual selective inhibitor of serotonin and norepinephrine uptake.</p>
    Formula:C19H21NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:295.38