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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5400 products of "Neuroscience"

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  • SB 699551

    CAS:
    <p>SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.</p>
    Formula:C34H45N3O
    Purity:99.83%
    Molecular weight:511.74
  • NMDAR antagonist 2


    <p>NMDAR antagonist 2 (compound 3I) is a blood-brain barrier permeable antagonist of NMDA receptors, exhibiting IC50 values of 4.42 μM and 214.75 μM at membrane potentials of -60 mV and 40 mV, respectively, for hGluN1/hGluN2A. This compound has been shown to mitigate hippocampal damage.</p>
    Formula:C17H20ClNO
    Color and Shape:Solid
    Molecular weight:289.8
  • Aβ1-14-εK-KKK-MvF5 Th


    <p>Aβ1-14-εK-KKK-MvF5 Th (UB311 immunogen I) is a biologically active peptide and one of the Aβ1–14 targeting peptides (B-cell epitope) used in UB-311.</p>
    Formula:C199H318N56O55
    Molecular weight:4372.38081
  • AChE-IN-45


    <p>AChE-IN-45 (Compound 14) is an acetylcholinesterase (AChE) inhibitor exhibiting an IC50 value of 11.57±0.45 nM, and it demonstrates both antioxidant and</p>
    Color and Shape:Odour Solid
  • Amyloid β-Protein (1-24)

    CAS:
    <p>Amyloid β-Protein (1-24) is a peptide identified through peptide screening. This tool predominantly employs immunoassays to gather and analyze active peptides. Peptide screening is utilized in studies involving protein interactions, functional analysis, and epitope screening, particularly relevant in the research and development of active molecules.</p>
    Formula:C130H183N35O40
    Molecular weight:2876.05
  • Doxacurium Chloride

    CAS:
    <p>Doxacurium Chloride is a muscarinic acetylcholine receptor M2 antagonist.</p>
    Formula:C56H78ClN2O16
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1070.69
  • Methoxy-X04

    CAS:
    <p>Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ).</p>
    Formula:C23H20O3
    Purity:98.96%
    Color and Shape:Solid
    Molecular weight:344.4
  • 4-P-PDOT

    CAS:
    <p>4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.</p>
    Formula:C19H21NO
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:279.38
  • BChE-IN-12

    CAS:
    <p>BChE-IN-12, non-competitive BChE inhibitor from Bletilla striata, IC50=2.3μM; potential Alzheimer’s research.</p>
    Formula:C31H30O5
    Color and Shape:Solid
    Molecular weight:482.57
  • BuChE-IN-11


    <p>BuChE-IN-11 (Compound 3b-1) is a selective inhibitor of BuChE with an IC50 of 0.44 μM for hBuChE. The compound demonstrates high brain-blood barrier permeability and possesses free radical scavenging capabilities, indicating significant antioxidant activity. BuChE-IN-11 interacts with the choline binding site, the acyl binding site, and the peripheral anionic site, showing submicromolar inhibitory activity against BuChE and preventing the self-aggregation of β-amyloid protein (Aβ). This compound holds promise for research in the field of Alzheimer's disease.</p>
    Formula:C28H27FN4O2
    Molecular weight:470.2118
  • Dicloromezotiaz

    CAS:
    <p>Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.</p>
    Formula:C19H12Cl3N3O2S
    Color and Shape:Solid
    Molecular weight:452.74
  • CHF-5022

    CAS:
    <p>CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).</p>
    Formula:C17H12F4O2
    Color and Shape:Solid
    Molecular weight:324.27
  • β-Amyloid (1-11)

    CAS:
    <p>Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluid</p>
    Formula:C56H76N16O22
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1325.3
  • Epiboxidine

    CAS:
    <p>Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.</p>
    Formula:C10H14N2O
    Color and Shape:Solid
    Molecular weight:178.23
  • Ro60-0175

    CAS:
    <p>Ro60-0175 is a selective 5-HT2B and 5-HT2C serotonin receptor agonist, often used as fumarate.</p>
    Formula:C11H12ClFN2
    Purity:97.09%
    Color and Shape:Solid
    Molecular weight:226.68
  • TB-11

    CAS:
    <p>TB-11 is an inhibitor of Cathepsin D with IC50 values of 0.126 nM (Cathepsin D), 1.92 nM (Cathepsin E), and 48.8 nM (BACE1). It is primarily utilized in oncological research.</p>
    Formula:C52H78N8O12
    Color and Shape:Solid
    Molecular weight:1007.22
  • R 50595

    CAS:
    <p>R 50595 is a selective non-competitive cisapride antagonist.</p>
    Formula:C30H35Cl2F2N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:594.52
  • GRGDSPK acetate

    CAS:
    <p>GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on integrins in bone formation and resorption.</p>
    Formula:C30H53N11O13
    Purity:97.9%
    Color and Shape:Soild
    Molecular weight:775.81
  • β-Amyloid (33-40)

    CAS:
    <p>β-Amyloid (33-40) is a peptide comprising amino acids 33 to 40 of the beta-amyloid protein.</p>
    Formula:C32H58N8O9S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:730.92
  • Dual AChE-MAO B-IN-3


    <p>Compound C10 is a potent dual AChE/MAO-B inhibitor with IC50s of 0.58μM (AChE) and 0.41μM (MAO-B), useful in Alzheimer's research.</p>
    Formula:C30H26F3NO3
    Color and Shape:Solid
    Molecular weight:505.53