Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(940 products)
- ACK(1 products)
- AChR(574 products)
- ATP Citrate Lyase(16 products)
- Adrenergic Receptor(2,943 products)
- BACE(36 products)
- Beta Amyloid(204 products)
- CaMK(68 products)
- Cyclooxygenase (COX) Inhibitors(561 products)
- Dopamine Receptor(407 products)
- GABA Receptor(336 products)
- Gamma-secretase(59 products)
- GluR(255 products)
- GlyT(24 products)
- Histamine Receptor(358 products)
- LRRK2(33 products)
- Melatonin Receptor(24 products)
- NMDAR(28 products)
- OX Receptor(40 products)
- Opioid Receptor(297 products)
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Found 5398 products of "Neuroscience"
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γ-Secretase-IN-1
CAS:<p>γ-Secretase-IN-1 is a γ-secretase inhibitor that displays partial antiproliferative activity against T-47D cells.</p>Formula:C27H24F2N4O3Purity:99.56%Color and Shape:SolidMolecular weight:490.5R-(+)-EU-1180-453
CAS:<p>R-(+)-EU-1180-453 is a novel GluN2C/D selective NMDAR-positive modulator for the study of neurological disorders.</p>Formula:C22H21FN2O3Purity:99.63%Color and Shape:SolidMolecular weight:380.41Dalzanemdor
CAS:<p>Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitive</p>Formula:C27H43F3O2Purity:98.2% - >99.99%Color and Shape:SolidMolecular weight:456.62Tematropium
CAS:<p>Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.</p>Formula:C21H31NO8SPurity:99.89%Color and Shape:SolidMolecular weight:457.54WAY-607695
CAS:<p>WAY-607695 is a potential 5-HT1A receptor agonist.</p>Formula:C13H12FNO2Purity:99.82%Color and Shape:SolidMolecular weight:233.24AMPA receptor modulator-1
CAS:<p>AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.</p>Formula:C16H11ClF3NO2Purity:99.93%Color and Shape:SolidMolecular weight:341.71Atabecestat
CAS:<p>Atabecestat (JNJ-54861911) is an oral BACE1 inhibitor for Alzheimer's treatment with strong brain uptake and lasting PK/PD effects.</p>Formula:C18H14FN5OSPurity:99.21% - 99.77%Color and Shape:SolidMolecular weight:367.4VU6004909
CAS:<p>VU6004909 is an mGlu5 receptor orthosteric modulator that reverses MK801-induced increased cortical activity and cognitive dysfunction.</p>Formula:C21H15FN2O4Purity:96.68% - 98.44%Color and Shape:SolidMolecular weight:378.35Gossypolone
CAS:<p>Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.</p>Formula:C30H26O10Purity:96.66%Color and Shape:SolidMolecular weight:546.52JNJ-42253432
CAS:<p>JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels</p>Formula:C28H38N4OPurity:99.98%Color and Shape:SolidMolecular weight:446.63Didesmethyl cariprazine
CAS:<p>Didesmethyl cariprazine, Cariprazine's active metabolite, treats schizophrenia/bipolar with D3/D2 affinity; half-life 1-3 weeks.</p>Formula:C19H28Cl2N4OPurity:99.52%Color and Shape:SolidMolecular weight:399.36SB 216641 hydrochloride
CAS:<p>SB 216641 hydrochloride (SB-216641A) is a 5-HT1B/D receptor antagonist with anxiolytic properties.</p>Formula:C28H31ClN4O4Purity:98.06% - 99.23%Color and Shape:SolidMolecular weight:523.02AMPA receptor antagonist-3
CAS:<p>AMPA receptor antagonist-3 is an AMPA receptor antagonist.</p>Formula:C20H19N5O2SPurity:99.79%Color and Shape:SolidMolecular weight:393.46CGP 78608 hydrochloride
CAS:<p>CGP 78608 hydrochloride: NMDA receptor antagonist (IC50=6 nM), anticonvulsant, enhances GluN1/GluN3A currents (EC50=26.3 nM).</p>Formula:C11H14BrClN3O5PPurity:99.85%Color and Shape:SolidMolecular weight:414.58BuChE-IN-TM-10
CAS:<p>TM-10: Potent BuChE inhibitor, IC50 8.9 nM, disaggregates Aβ, antioxidant, BBB penetrant, may treat Alzheimer's.</p>Formula:C32H38N2O3Purity:99.54%Color and Shape:SolidMolecular weight:498.66Osemozotan HCl
CAS:<p>Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.</p>Formula:C19H22ClNO5Purity:98.87% - 99.63%Color and Shape:SolidMolecular weight:379.84TZ3O
CAS:<p>TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment in Scopolamine-induced Alzheimer's type model in rats.</p>Formula:C18H13NO4SPurity:99.84%Color and Shape:SolidMolecular weight:339.37BMS-986176
CAS:<p>AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).</p>Formula:C19H23F4N3OPurity:98.58% - 98.7%Color and Shape:SolidMolecular weight:385.4Lumateperone
CAS:<p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>Formula:C24H28FN3OPurity:99.68% - 99.91%Color and Shape:SolidMolecular weight:393.5PXS-5120A
CAS:<p>PXS-5120A is an irreversible fluoroallylamine Lysyl Oxidase-like 2/3 (LOXL2/3) inhibitor with anti-fibrotic activity.</p>Formula:C22H25ClFN3O4SPurity:97.02%Color and Shape:SolidMolecular weight:481.97MDR-1339
CAS:<p>MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.</p>Formula:C20H22O4Purity:98.57%Color and Shape:SolidMolecular weight:326.39PXS-5153A
CAS:<p>PXS-5153A rapidly inhibits lysyl oxidase 2/3 enzymes, blocks activity in 15 mins, and reduces fibrosis.</p>Formula:C20H25Cl2FN4O2SPurity:99.58%Color and Shape:SolidMolecular weight:475.41SB-616234-A
CAS:<p>SB-616234-A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant activity.</p>Formula:C32H36ClN5O3Purity:99.72%Color and Shape:SolidMolecular weight:574.11Dihydro-β-erythroidine
CAS:<p>Dihydro-β-erythroidine, a competitive nicotinic receptor antagonist, effectively blocks the discriminative stimulus properties and inhibits the anxiolytic</p>Formula:C16H21NO3Color and Shape:SolidMolecular weight:275.34Notch inhibitor 1
CAS:<p>Notch inhibitor 1 blocks Notch 1/3 (IC50: 7.8/8.5 nM) and aids cancer research.</p>Formula:C26H25F7N4O3Purity:98%Color and Shape:SolidMolecular weight:574.49CPPG
CAS:<p>CPPG: potent group II/III mGlu receptor antagonist, 20x more selective for group III (IC50: 2.2 nM) than II (46.2 nM) in rat cortex.</p>Formula:C11H14NO5PColor and Shape:SolidMolecular weight:271.21MAO-IN-4
CAS:<p>MAO-IN-4 (Compound 2l), a monoamine oxidase (MAO) inhibitor, demonstrates IC50 values of 0.07 μM for MAO-A and 0.75 μM for MAO-B. This compound is utilized in studying depression and Parkinson's disease (PD) [1].</p>Formula:C18H11Cl2N3OSColor and Shape:SolidMolecular weight:388.27AChE/BChE-IN-1
<p>AChE/BChE-IN-1: dual AChE/BChE inhibitor, IC50 of 1.06 nM/7.3 nM, crosses blood-brain barrier, with antioxidant properties for Alzheimer's research.</p>Formula:C32H35ClN6O3Color and Shape:SolidMolecular weight:587.11γ-secretase modulator 6
CAS:<p>Gamma-secretase modulator 6 (Example 50) is a gamma-secretase modulator. It inhibits Aβ42 secretion in HEK cell lines stably expressing APP (Aβ amyloid precursor protein) with a pIC50 of 8.1. This compound is applicable in Alzheimer's disease research.</p>Formula:C25H26N6O2Color and Shape:SolidMolecular weight:442.513GABAA receptor agonist 2
<p>Compound 4c, a potent GABAA agonist with anti-depressive effects in mouse FST/TST, shows promise in depression research.</p>Formula:C22H36O5Color and Shape:SolidMolecular weight:380.52Sulamserod hydrochloride
CAS:<p>Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.</p>Formula:C19H29Cl2N3O5SColor and Shape:SolidMolecular weight:482.42DA-8031
CAS:<p>DA-8031 is a selective and orally active serotonin reuptake inhibitor. It is utilized in research related to premature ejaculation (PE).</p>Formula:C21H24N2O2Color and Shape:SolidMolecular weight:336.43Nafimidone hydrochloride
CAS:<p>Nafimidone hydrochloride, an antiepileptic agent, inhibits acetylcholinesterase, protects neurons, and ameliorates cognitive decline. It is utilized in epilepsy research.</p>Formula:C15H13ClN2OColor and Shape:SolidMolecular weight:272.73RTIOXA-43
CAS:<p>RTIOXA-43 is an OX2R/OX1R (orexin receptor) dual agonist that increases wakefulnesand is commonly used in studies related to narcolepsy and neural signaling.</p>Formula:C37H37N5O5SPurity:99.17%Color and Shape:SolidMolecular weight:663.79SEP-363856 mesylate
CAS:<p>SEP-363856 (SEP-856) mesylate is an orally active compound that acts as an agonist for both TAAR1 and 5-HT1A receptors. This compound exhibits antipsychotic activity in the central nervous system and has potential for the study of schizophrenia.</p>Formula:C10H17NO4S2Color and Shape:SolidMolecular weight:279.38Anti-Aβ agent 1A
<p>Anti-Aβ agent 1A is a potent anti-amyloid-β agent.</p>Formula:C35H49NO4Color and Shape:SolidMolecular weight:547.77CVN766
CAS:<p>CVN766 is an orally active orexin 1 receptor antagonist with blood-brain permeability, demonstrating IC50 values of 8 nM for OX1R and >10 μM for OX2R. CVN766 can be used to study schizophrenia [1].</p>Formula:C20H21F3N8OColor and Shape:SolidMolecular weight:446.43(+)-Cevimeline hydrochloride hemihydrate
<p>(+)-Cevimeline HCl hemihydrate is a muscarinic agonist for dry mouth in Sjogren's with rapid absorption, differing metabolism in species.</p>Formula:C10H19ClNO1·5SPurity:98%Color and Shape:SolidMolecular weight:244.78FCOB02
CAS:<p>FCOB02 is a monoamine oxidase B (MAO-B) ligand. It can be labeled as [18F]FCOB02, serving as a 4-methylcoumarin-like targeting probe. [18F]FCOB02 demonstrates high affinity for MAO-B, with an IC50 of 10.68 nM. It is utilized for specific imaging and quantitative analysis of MAO-B in vivo.</p>Formula:C16H12FNO3Color and Shape:SolidMolecular weight:285.27Buntanetap L-Tartrate
CAS:<p>Buntanetap (L-Tartrate) functions as an oral small molecule inhibitor targeting multiple neurotoxic proteins. It decreases the production of amyloid precursor protein (APP) by inhibiting the translation of its mRNA [1].</p>Formula:C24H29N3O8Color and Shape:SolidMolecular weight:487.50S-8510 phosphate
CAS:<p>S-8510 phosphate is an agonist of inverse Benzodiazepine (BDZ) receptor(Kis of 34.6 nM, 36.2 nM for –GABA and +GABA respectively).</p>Formula:C12H13N4O6PPurity:98%Color and Shape:SolidMolecular weight:340.23Moxetomidate
CAS:<p>Moxetomidate is a GABAA receptor (GABAA receptor) agonist with hypnotic properties.</p>Formula:C15H18N2O3Color and Shape:SolidMolecular weight:274.315AChE/BChE/MAO-B-IN-5
CAS:<p>AChE/BChE/MAO-B-IN-5 is a multi-target inhibitor capable of crossing the blood-brain barrier, targeting cholinesterases (AChE and BChE) and monoamine oxidase MAO-B. It exhibits IC50 values of 0.24 µM for AChE, 6.29 µM for BChE, and 0.11 µM for MAO-B. AChE/BChE/MAO-B-IN-5 holds potential for research in neurodegenerative diseases such as Alzheimer's disease.</p>Formula:C22H14F3NO2Color and Shape:SolidMolecular weight:381.347AAZ-A 154 hydrobromide
CAS:<p>AAZ-A 154 hydrobromide is a selective, competitive, non-hallucinogenic 5-HT2AR antagonist. It promotes neuronal growth in rodents and yields enduring beneficial behavioral effects.</p>Formula:C14H21BrN2OColor and Shape:SolidMolecular weight:313.23Gabaculine HCl
CAS:<p>Gabaculine, an irreversible GABA-T inhibitor (Ki: 2.9 μM), impacts plastid development and affects DPOR/GluTR levels.</p>Formula:C7H10ClNO2Color and Shape:SolidMolecular weight:175.61BACE1-IN-4
CAS:<p>BACE1-IN-4 is a potent and highly selective BACE1 inhibitor (IC50: 3.8 nM; Ki: 1.9 nM), more selective at BACE1 over BACE2.</p>Formula:C21H23F2N5O4S2Purity:98%Color and Shape:SolidMolecular weight:511.57AAZ-A 154 benzoate
CAS:<p>AAZ-A 154 benzoate is a selective, competitive, and non-hallucinogenic 5-HT2AR antagonist. This compound facilitates neuronal growth in rodents and produces lasting beneficial behavioral effects.</p>Formula:C21H26N2O3Color and Shape:SolidMolecular weight:354.44eeAChE-IN-1
<p>eeAChE-IN-1 is a strong inhibitor of eeAChE (IC50: 23 nM).</p>Formula:C27H30N6O5SColor and Shape:SolidMolecular weight:550.63SB 224289
CAS:<p>SB 224289: selective 5-HT1B antagonist, pKi 8.2, 60x selectivity, effective orally.</p>Formula:C32H32N4O3Purity:98%Color and Shape:SolidMolecular weight:520.62AAZ-A 154 hydrochloride
CAS:<p>AAZ-A 154 hydrochloride is a selective, competitive, non-hallucinogenic antagonist of 5-HT2AR. It promotes neuronal growth in rodents and results in enduring beneficial behavioral effects.</p>Formula:C14H21ClN2OColor and Shape:SolidMolecular weight:268.78
