Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(1,025 products)
- ACK(1 products)
- AChR(645 products)
- ATP Citrate Lyase(17 products)
- Adrenergic Receptor(3,018 products)
- BACE(37 products)
- Beta Amyloid(228 products)
- CaMK(73 products)
- Cyclooxygenase (COX) Inhibitors(600 products)
- Dopamine Receptor(445 products)
- GABA Receptor(372 products)
- Gamma-secretase(61 products)
- GluR(265 products)
- GlyT(26 products)
- Histamine Receptor(385 products)
- LRRK2(43 products)
- Melatonin Receptor(26 products)
- NMDAR(10 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
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Found 5548 products of "Neuroscience"
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UNC9994 hydrochloride
CAS:UNC9994 hydrochloride is a selective β-arrestin-biased D2R agonist, Ki of 79 nM, that stimulates β-arrestin and modulates cAMP.Formula:C21H23Cl3N2OSColor and Shape:SolidMolecular weight:457.84(S)-Renzapride
(S)-Renzapride (BRL 24924), 5-HT4 agonist (Ki 115 nM), 5HT2b/5HT3 antagonist, for C-IBS study.Formula:C16H22ClN3O2Color and Shape:SolidMolecular weight:323.82MDL-74156
CAS:MDL-74156 is an active metabolite of dolasetron and a 5-hydroxy-tryptamine3 (5-HT3) antagonist.Formula:C19H22N2O3Color and Shape:SolidMolecular weight:326.39eeAChE-IN-2
CAS:eeAChE-IN-2 is a potent inhibitor of eeAChE, exhibiting inhibitory potency with an IC50 of 2 nM.Formula:C37H40N8O5SColor and Shape:SolidMolecular weight:708.83Nemonapride
CAS:Nemonapride is a dopamine D2-like receptor antagonist.Formula:C21H26ClN3O2Purity:98%Color and Shape:SolidMolecular weight:387.9GR-127935
CAS:GR-127935 is a potent and selective 5-HT1B/1D receptor antagonist.Formula:C29H31N5O3Color and Shape:SolidMolecular weight:497.59AMG-8718
CAS:AMG-8718, an oral BACE1 blocker (IC50: 0.0007 μM), also inhibits BACE2 (IC50: 0.005 μM), lowering CSF and Aβ40 brain levels.Formula:C25H19FN4O3Color and Shape:SolidMolecular weight:442.44UNC9994
CAS:UNC9994 is a β-arrestin-biased dopamine D₂ receptor agonist (β-arrestin EC50 = 50 nM; Emax = 97%) with robust in vivo antipsychotic drug-like activities.Formula:C21H22Cl2N2OSColor and Shape:SolidMolecular weight:421.38NAS-181
CAS:NAS-181 is a potent and selective rat 5-hydroxytryptamine 1B (r5-HT1B) antagonist (Ki: 47 nM).NAS-181 enhances the accumulation of 5-HTP in rat brain regions.Formula:C20H30N2O7SColor and Shape:SolidMolecular weight:442.53CGP 55845 hydrochloride
CAS:CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC 50 of 6 nM which can be used in neurological research [1] [2].Formula:C18H23Cl3NO3PColor and Shape:SolidMolecular weight:438.71PZ-1190
CAS:PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents [1].Formula:C27H30N4O2S2Purity:98%Color and Shape:SolidMolecular weight:506.68Brasofensine Maleate
CAS:Brasofensine Maleate inhibits the monoamine re-uptake.Formula:C20H24Cl2N2O5Color and Shape:SolidMolecular weight:443.32NAS181
CAS:rat 5-HT1B receptor antagonistFormula:C21H34N2O10S2Purity:98%Color and Shape:SolidMolecular weight:538.63N-Demethyl MK-6884
CAS:N-Demethyl MK-6884 (compound 34) is an M4 mAChR modulator for Alzheimer's and related disease research.Formula:C24H23N5OColor and Shape:SolidMolecular weight:397.47GABAA receptor agent 2 TFA
CAS:Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.Formula:C22H22F3N3O3Color and Shape:SolidMolecular weight:433.42Mesembrine
CAS:Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).Formula:C17H23NO3Color and Shape:SolidMolecular weight:289.37VU 0255035
CAS:VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.
Formula:C18H20N6O3S2Purity:98.09% - 98.1%Color and Shape:SolidMolecular weight:432.52MAO-B-IN-1
CAS:MAO-B-IN-1 is a monoamine oxidase B inhibitor and can be used for the research of neurological diseases.Formula:C16H14F3N3O2SPurity:98%Color and Shape:SolidMolecular weight:369.36GYKI-46903 HCl
CAS:GYKI-46903 is a noncompetitive 5-HT3 receptor antagonist.Formula:C17H21ClFNO2Color and Shape:SolidMolecular weight:325.81LY3202626
CAS:LY3202626, an amyloid precursor protein secretase (BACE protein) inhibitor, is used for the treatment of Alzheimer's disease.Formula:C22H20F2N8O2SPurity:98%Color and Shape:SolidMolecular weight:498.51BACE1-IN-10
CAS:BACE1-IN-10 is a potent inhibitor of BACE1, demonstrating sub-micromolar activity against recombinant BACE1 (rBACE1) [1].Formula:C33H49N5O8SPurity:98%Color and Shape:SolidMolecular weight:675.84Fosthiazate
CAS:Fosthiazate is a broad-spectrum nematicide that combats a range of plant parasitic nematodes such as Meloidogyne spp., Globodera spp., and Pratylenchus spp., byFormula:C9H18NO3PS2Purity:97.78%Color and Shape:SolidMolecular weight:283.35FPPQ
CAS:FPPQ blocks 5-HT3 and 5-HT6 receptors (Ki: 0.9 & 3 nM) and may improve psychosis and cognition.Formula:C21H19FN4O2SColor and Shape:SolidMolecular weight:410.46MIN-117
CAS:MIN-117, a SSRI/5-HT receptor antagonist, is potentially used for the treatment of depression.Formula:C25H26Cl3N3O4Purity:98%Color and Shape:SolidMolecular weight:538.855-HT3-In-1
CAS:5-HT3-In-1 (compound example 8) exhabits with 5-HT3 inhibition activity.Formula:C16H21ClN4O3Purity:98%Color and Shape:SolidMolecular weight:352.82Serine Hydrolase inhibitor-21
CAS:Serine Hydrolase Inhibitor-21 (compound 8), a pyridine-based serine hydrolase inhibitor, exhibits a K i of 429 nM against BuChE, and shows promise for AlzheimerFormula:C18H12N2O2SPurity:98%Color and Shape:SolidMolecular weight:320.37VU6012962
CAS:VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).Formula:C21H19F3N4O4Purity:99.61% - 99.74%Color and Shape:SolidMolecular weight:448.4Ref: TM-T13323
1mg34.00€2mg49.00€5mg74.00€10mg119.00€25mg225.00€50mg404.00€100mg592.00€1mL*10mM (DMSO)82.00€Brasofensine sulfate
CAS:Brasofensine sulfate is a dopamine reuptake inhibitor.Formula:C16H22Cl2N2O5SColor and Shape:SolidMolecular weight:425.33rel-HDMP 28 hydrochloride
CAS:Rel-HDMP-28 hydrochloride (Compound 2g) is an analogue of methylphenidate, exhibiting selective affinity for the serotonin transporter (SERT) with a binding constant (Ki) of 105 nM [1].Formula:C18H22ClNO2Color and Shape:SolidMolecular weight:319.83Cyclophostin
CAS:Cyclophostin is an irreversible inhibitor of acetylcholinesterase (AChE).Formula:C8H11O6PPurity:98%Color and Shape:SolidMolecular weight:234.146,2'-Dihydroxyflavone
CAS:6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.Formula:C15H10O4Purity:99.44% - 99.67%Color and Shape:SolidMolecular weight:254.24Indeloxazine hydrochloride
CAS:Indeloxazine HCl: Serotonin releaser, NE reuptake inhibitor, NMDA antagonist; antidepressant that boosts acetylcholine in rats.Formula:C14H18ClNO2Purity:98%Color and Shape:SolidMolecular weight:267.75Robalzotan
CAS:Robalzotan is a selective 5-HT1A receptor antagonist.Formula:C18H23FN2O2Purity:98%Color and Shape:SolidMolecular weight:318.39KBR 2822
CAS:KBR 2822 is an inhibitor of esterase.Formula:C9H15ClF3O3PSPurity:98%Color and Shape:SolidMolecular weight:326.7JM-1232
CAS:JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic.Formula:C24H27N3O2Color and Shape:SolidMolecular weight:389.49CGP-54626 free base
CAS:CGP-54626 is a selective antagonist of the GABAB receptor (IC50 = 4 nM ).Formula:C18H28Cl2NO3PPurity:98%Color and Shape:SolidMolecular weight:408.3MAO-B-IN-27
CAS:MAO-B-IN-27 (Compound 12c), a monoamine oxidase B (MAO-B) inhibitor, exhibits a potent and selective inhibitory effect on hMAO-B, with an IC50 value of 8.9 nM,Formula:C16H17ClF3NOPurity:98%Color and Shape:SolidMolecular weight:331.765-HT2C agonist-3
CAS:5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits antipsychotic-like activity by blocking amphetamine-inducedFormula:C19H23ClFNO2Purity:98%Color and Shape:SolidMolecular weight:351.84L-772,405
CAS:L-772,405 is a highly selective agonists of h5-HT(1D) receptor.Formula:C26H31FN6OPurity:98%Color and Shape:SolidMolecular weight:462.56Frovatriptan
CAS:Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.Formula:C14H17N3OPurity:100%Color and Shape:SolidMolecular weight:243.3Adenylyl cyclase-IN-1
CAS:Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1].Formula:C9H8N2S3Color and Shape:SolidMolecular weight:240.37(R)-4-Amino-3-hydroxybutyric Acid
CAS:(R)-4-Amino-3-hydroxybutyric acid, also known as (R)-GABOB, acts as a modulator of GABA receptors, specifically binding to both GABAA and GABAB receptors and blocking GABA reuptake in rat brain synaptosomes. Additionally, it serves as a GABAC receptor agonist, triggering currents in patch-clamp assays with Xenopus oocytes that express the human receptor. In vivo studies reveal its capability to suppress electrical discharges in the amygdala in cats undergoing N-amidinobenzamide-triggered seizures, indicating its potential therapeutic application in managing seizure disorders.Formula:C4H9NO3Color and Shape:SolidMolecular weight:119.12(S)-Bexicaserin
CAS:(S)-Bexcaserin (compound 2) serves as a 5-HT2C receptor agonist, presenting research possibilities in obesity and psychiatric disorders [1].Formula:C15H19F2N3OPurity:98%Color and Shape:SolidMolecular weight:295.33Physostigmine hemisulfate
CAS:cholinesterase inhibitorFormula:C15H21N302H204SPurity:98%Color and Shape:SolidMolecular weight:324.39BMS-933043
CAS:BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) & human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).Formula:C16H19N7OPurity:98%Color and Shape:SolidMolecular weight:325.37MAO-B-IN-19
CAS:MAO-B-IN-19, a selective MAO-B inhibitor, exhibits neuroprotective and anti-inflammatory properties and demonstrates an IC50 value of 0.67 μM [1].Formula:C15H11FO2Purity:98%Color and Shape:SolidMolecular weight:242.25Octahydroaminoacridine succinate
CAS:Octahydroaminoacridine succinate, an acetylcholinesterase inhibitor, is used potentially for the treatment of Alzheimer's disease.Formula:C17H24N2O4Purity:99.91%Color and Shape:SolidMolecular weight:320.38β-Secretase Inhibitor IV
CAS:β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).Formula:C31H38N4O5SPurity:98%Color and Shape:SolidMolecular weight:578.72Biphenylindanone A
CAS:Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders.Formula:C30H30O4Purity:98%Color and Shape:SolidMolecular weight:454.56FGIN-1-27
CAS:FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).Formula:C28H37FN2OPurity:99.86%Color and Shape:SolidMolecular weight:436.6
