Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(1,025 products)
- ACK(1 products)
- AChR(645 products)
- ATP Citrate Lyase(17 products)
- Adrenergic Receptor(3,018 products)
- BACE(37 products)
- Beta Amyloid(228 products)
- CaMK(73 products)
- Cyclooxygenase (COX) Inhibitors(600 products)
- Dopamine Receptor(445 products)
- GABA Receptor(372 products)
- Gamma-secretase(61 products)
- GluR(265 products)
- GlyT(26 products)
- Histamine Receptor(385 products)
- LRRK2(43 products)
- Melatonin Receptor(26 products)
- NMDAR(10 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
Show 12 more subcategories
Found 5548 products of "Neuroscience"
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AChE-IN-31
CAS:AChE-IN-31 (compound 1), a non-competitive acetylcholinesterase (AChE) inhibitor, exhibits potential for Alzheimer's disease research [1].Formula:C27H44Na2O9S2Color and Shape:SolidMolecular weight:622.74VU0029251
CAS:VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.Formula:C10H11N3S2Color and Shape:SolidMolecular weight:237.34COR659
CAS:COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.Formula:C16H16ClNO3SPurity:99.75%Color and Shape:SolidMolecular weight:337.82Ref: TM-T36520
1mg38.00€5mg86.00€10mg123.00€25mg215.00€50mg299.00€100mg411.00€200mg560.00€1mL*10mM (DMSO)94.00€Aβ/tau aggregation-IN-3
CAS:Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functionalFormula:C23H22N4O3Color and Shape:SolidMolecular weight:402.45CGP 54626 hydrochloride
CAS:CGP 54626 hydrochloride is a GABAB receptor antagonist.Formula:C18H29Cl3NO3PPurity:98%Color and Shape:SolidMolecular weight:444.76FK-1052
CAS:FK-1052 is a serotonin 3 & 4 dual receptor antagonist.Formula:C18H19N3OColor and Shape:SolidMolecular weight:293.365-HT3 antagonist 1
CAS:5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.Formula:C22H27N5OPurity:98%Color and Shape:SolidMolecular weight:377.48R-96544
CAS:R-96544 is an orally active antagonist of the 5-HT2A receptor that has demonstrated the ability to inhibit platelet aggregation in vitro [1].Formula:C22H30ClNO3Color and Shape:SolidMolecular weight:391.93mGluR5 antagonist-1
CAS:mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].Formula:C23H18N4O2Color and Shape:SolidMolecular weight:382.41Brasofensine
CAS:Brasofensine, a benztoalkane MA reuptake inhibitor, shows promise for Parkinson's and Alzheimer's.Formula:C16H20Cl2N2OColor and Shape:SolidMolecular weight:327.25Brilaroxazine
CAS:Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.Formula:C22H25Cl2N3O3Purity:99.36%Color and Shape:SolidMolecular weight:450.36Ref: TM-T14782
1mg100.00€5mg236.00€10mg385.00€25mg663.00€50mg954.00€100mg1,305.00€200mg1,738.00€1mL*10mM (DMSO)268.00€Brasofensine Maleate
CAS:Brasofensine Maleate inhibits the monoamine re-uptake.Formula:C20H24Cl2N2O5Color and Shape:SolidMolecular weight:443.32GSM-1
CAS:GSM-1 is a modulator of γ-Secretase.Formula:C26H31ClF3NO2Color and Shape:SolidMolecular weight:481.98BACE-1 inhibitor 1
CAS:BACE-1 inhibitor 1 (Compound 8a) is an effective BACE-1 inhibitor (IC50: 56 nM).Formula:C17H14BrF3N4O2Purity:98%Color and Shape:SolidMolecular weight:443.22Piperidine-4-sulfonic acid
CAS:Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].Formula:C5H11NO3SPurity:98%Color and Shape:SolidMolecular weight:165.21FGIN-1-27
CAS:FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).Formula:C28H37FN2OPurity:99.86%Color and Shape:SolidMolecular weight:436.6VU6007477
CAS:VU6007477 is a brain-penetrant M1 muscarinic receptor PAM (EC50 230 nM) used for research on CNS exposure and seizure-related models.Formula:C24H26N6O2Purity:99.67%Color and Shape:SolidMolecular weight:430.5GR 125487 sulfamate
CAS:GR 125487 sulfamate is a 5-HT4 receptor antagonist.Formula:C19H29FN4O8S2Purity:98%Color and Shape:SolidMolecular weight:524.58MRK-560
CAS:MRK-560 is an effective and brain-penetrant inhibitor of γ-secretase.Formula:C19H17ClF5NO4S2Purity:98.87%Color and Shape:SolidMolecular weight:517.92LY2033298
CAS:LY2033298 enhances oximoline's effect on hamster circadian rhythms, aiding neurosystem disorders.Formula:C13H14ClN3O2SPurity:98.78%Color and Shape:SolidMolecular weight:311.79BMS-932481
CAS:BMS-932481 is a γ-secretase modulator.Formula:C24H24FN7OColor and Shape:SolidMolecular weight:445.491-Carboxycyclohexaneacetic Acid
CAS:1-Carboxycyclohexaneacetic acid may be present as a potential impurity in commercial gabapentin, an antiepileptic drug. Furthermore, it serves as a precursor for synthesizing antagonists targeting the serotonin (5-HT) receptor subtype 5-HT2A.Formula:C9H14O4Color and Shape:SolidMolecular weight:186.207Anti-amyloid agent-1
CAS:Anti-amyloid agent-1 is a potent compound that inhibits amyloid aggregation, offering a promising approach for research into the treatment of amyloidosis [1].Formula:C21H17F3N2O3Color and Shape:SolidMolecular weight:402.37BMT-124110
CAS:BMT-124110: AAK1 inhibitor, IC50=0.9 nM, pain relief. BMT-090605: BIKE inhibitor, IC50=17 nM; GAK inhibitor, IC50=99 nM.Formula:C21H27N3O3Purity:98.07%Color and Shape:SolidMolecular weight:369.46CGP36216 hydrochloride
CAS:CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].Formula:C5H15ClNO2PColor and Shape:SolidMolecular weight:187.6BChE-IN-20
CAS:BChE-IN-20 (compound 7c) is a potent, selective inhibitor of BChE, demonstrating IC50 values of 105 nM for eqBChE and 2.3 nM for hBChE.Formula:C27H39N5O2Color and Shape:SolidMolecular weight:465.63QR-0217
CAS:QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.Formula:C19H13NO3Color and Shape:SolidMolecular weight:303.31WAY-607695
CAS:WAY-607695 is a potential 5-HT1A receptor agonist.Formula:C13H12FNO2Purity:99.82%Color and Shape:SolidMolecular weight:233.24BuChE-IN-TM-10
CAS:TM-10: Potent BuChE inhibitor, IC50 8.9 nM, disaggregates Aβ, antioxidant, BBB penetrant, may treat Alzheimer's.Formula:C32H38N2O3Purity:99.54%Color and Shape:SolidMolecular weight:498.66VU6004909
CAS:VU6004909 is an mGlu5 receptor orthosteric modulator that reverses MK801-induced increased cortical activity and cognitive dysfunction.Formula:C21H15FN2O4Purity:96.68% - 98.44%Color and Shape:SolidMolecular weight:378.35Osemozotan HCl
CAS:Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.Formula:C19H22ClNO5Purity:98.87% - 99.63%Color and Shape:SolidMolecular weight:379.84Philanthotoxin 74 dihydrochloride
CAS:Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.Formula:C24H44Cl2N4O3Purity:99.75%Color and Shape:SolidMolecular weight:507.54Tematropium
CAS:Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.Formula:C21H31NO8SPurity:99.89%Color and Shape:SolidMolecular weight:457.54Ref: TM-T10732
1mg147.00€5mg356.00€10mg558.00€25mg880.00€50mg1,179.00€100mg1,603.00€200mg2,152.00€1mL*10mM (DMSO)413.00€R-(+)-EU-1180-453
CAS:R-(+)-EU-1180-453 is a novel GluN2C/D selective NMDAR-positive modulator for the study of neurological disorders.Formula:C22H21FN2O3Purity:99.63%Color and Shape:SolidMolecular weight:380.41SB 216641 hydrochloride
CAS:SB 216641 hydrochloride (SB-216641A) is a 5-HT1B/D receptor antagonist with anxiolytic properties.Formula:C28H31ClN4O4Purity:98.06% - 99.23%Color and Shape:SolidMolecular weight:523.02γ-Secretase-IN-1
CAS:γ-Secretase-IN-1 is a γ-secretase inhibitor that displays partial antiproliferative activity against T-47D cells.Formula:C27H24F2N4O3Purity:99.56%Color and Shape:SolidMolecular weight:490.5Ref: TM-T3521
1mg120.00€5mg385.00€10mg618.00€25mg1,224.00€50mg1,648.00€100mg2,232.00€1mL*10mM (DMSO)416.00€Atabecestat
CAS:Atabecestat (JNJ-54861911) is an oral BACE1 inhibitor for Alzheimer's treatment with strong brain uptake and lasting PK/PD effects.Formula:C18H14FN5OSPurity:99.21% - 99.77%Color and Shape:SolidMolecular weight:367.4Ref: TM-T14338
1mg123.00€5mg295.00€10mg477.00€25mg954.00€50mg1,279.00€100mg1,728.00€1mL*10mM (DMSO)326.00€TZ3O
CAS:TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment in Scopolamine-induced Alzheimer's type model in rats.Formula:C18H13NO4SPurity:99.84%Color and Shape:SolidMolecular weight:339.37AMPA receptor antagonist-3
CAS:AMPA receptor antagonist-3 is an AMPA receptor antagonist.Formula:C20H19N5O2SPurity:99.79%Color and Shape:SolidMolecular weight:393.46Ref: TM-T61813
1mg185.00€5mg425.00€10mg625.00€25mg938.00€50mg1,311.00€100mg1,795.00€1mL*10mM (DMSO)455.00€Didesmethyl cariprazine
CAS:Didesmethyl cariprazine, Cariprazine's active metabolite, treats schizophrenia/bipolar with D3/D2 affinity; half-life 1-3 weeks.Formula:C19H28Cl2N4OPurity:99.52%Color and Shape:SolidMolecular weight:399.36AMPA receptor modulator-1
CAS:AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.
Formula:C16H11ClF3NO2Purity:99.93%Color and Shape:SolidMolecular weight:341.71PXS-5120A
CAS:PXS-5120A is an irreversible fluoroallylamine Lysyl Oxidase-like 2/3 (LOXL2/3) inhibitor with anti-fibrotic activity.Formula:C22H25ClFN3O4SPurity:97.02%Color and Shape:SolidMolecular weight:481.97Ref: TM-T12584
1mg205.00€2mg293.00€5mg462.00€10mg612.00€25mg893.00€50mg1,224.00€100mg1,639.00€1mL*10mM (DMSO)502.00€BMS-986176
CAS:AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).
Formula:C19H23F4N3OPurity:98.58% - 98.7%Color and Shape:SolidMolecular weight:385.4SB-616234-A
CAS:SB-616234-A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant activity.Formula:C32H36ClN5O3Purity:99.72%Color and Shape:SolidMolecular weight:574.11MDR-1339
CAS:MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.Formula:C20H22O4Purity:98.57%Color and Shape:SolidMolecular weight:326.39Lumateperone
CAS:Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).Formula:C24H28FN3OPurity:99.68% - 99.91%Color and Shape:SolidMolecular weight:393.5PXS-5153A
CAS:PXS-5153A rapidly inhibits lysyl oxidase 2/3 enzymes, blocks activity in 15 mins, and reduces fibrosis.Formula:C20H25Cl2FN4O2SPurity:99.58%Color and Shape:SolidMolecular weight:475.41Ro4368554
CAS:Ro4368554 is a selective 5-HT6 antagonist capable of crossing the blood-brain barrier. It can reverse memory deficits caused by scopolamine and tryptophan depletion. Ro4368554 is applicable for research related to memory impairments.Formula:C19H21N3O2SColor and Shape:SolidMolecular weight:355.454LY-2979165
CAS:LY-2979165 is a metabotropic glutamate receptor agonist prodrug.Formula:C13H17N5O5SColor and Shape:SolidMolecular weight:355.37PXS-5153A monohydrochloride
CAS:PXS-5153A is an oral, fast-acting LOXL2/3 inhibitor with IC50 <40 nM for LOXL2 and 63 nM for LOXL3, potentially treating fibrosis.Formula:C20H25Cl2FN4O2SPurity:98%Color and Shape:Odour SolidMolecular weight:475.41
