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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5400 products of "Neuroscience"

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  • AAZ-A 154 hydrobromide
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    AAZ-A 154 hydrobromide

    CAS:
    <p>AAZ-A 154 hydrobromide is a selective, competitive, non-hallucinogenic 5-HT2AR antagonist. It promotes neuronal growth in rodents and yields enduring beneficial behavioral effects.</p>
    Formula:C14H21BrN2O
    Color and Shape:Solid
    Molecular weight:313.23

    Ref: TM-T200446

  • AAZ-A 154 benzoate
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    AAZ-A 154 benzoate

    CAS:
    <p>AAZ-A 154 benzoate is a selective, competitive, and non-hallucinogenic 5-HT2AR antagonist. This compound facilitates neuronal growth in rodents and produces lasting beneficial behavioral effects.</p>
    Formula:C21H26N2O3
    Color and Shape:Solid
    Molecular weight:354.44

    Ref: TM-T200491

  • AAZ-A 154 hydrochloride
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    AAZ-A 154 hydrochloride

    CAS:
    <p>AAZ-A 154 hydrochloride is a selective, competitive, non-hallucinogenic antagonist of 5-HT2AR. It promotes neuronal growth in rodents and results in enduring beneficial behavioral effects.</p>
    Formula:C14H21ClN2O
    Color and Shape:Solid
    Molecular weight:268.78

    Ref: TM-T200509

  • AAZ-A 154 mesylate
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    AAZ-A 154 mesylate

    CAS:
    <p>AAZ-A 154 mesylate mesylate is a selective, competitive, and non-hallucinogenic antagonist of 5-HT2AR. It enhances neuronal growth in rodents and produces enduring beneficial behavioral effects.</p>
    Formula:C15H24N2O4S
    Color and Shape:Solid
    Molecular weight:328.43

    Ref: TM-T200486

  • Befiradol hydrochloride
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    Befiradol hydrochloride

    CAS:
    <p>Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.</p>
    Formula:C20H23Cl2F2N3O
    Purity:99.1%
    Color and Shape:Solid
    Molecular weight:430.32

    Ref: TM-T62385

  • (RS)-AMPA hydrochloride
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    (RS)-AMPA hydrochloride

    CAS:
    <p>(RS)-AMPA ((±)-AMPA) hydrochloride is a glutamate analog and serves as an efficient selective agonist for the excitatory neurotransmitter L-glutamic acid (L-glutamic acid). It does not interfere with the binding sites of alginate or NMDA receptors.</p>
    Formula:C7H11ClN2O4
    Color and Shape:Solid
    Molecular weight:222.63

    Ref: TM-T200780

  • AAZ-A 154
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    AAZ-A 154

    CAS:
    <p>AAZ-A 154 is a selective, competitive, and non-hallucinogenic antagonist of the 5-HT2AR. It promotes neuronal growth in rodents and results in lasting beneficial behavioral effects.</p>
    Formula:C14H20N2O
    Color and Shape:Solid
    Molecular weight:232.32

    Ref: TM-T200737

  • Lu 26-046
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    Lu 26-046

    CAS:
    <p>Lu 26-046 is a muscarinic receptor agonist.</p>
    Formula:C10H12N2OS
    Color and Shape:Solid
    Molecular weight:208.28

    Ref: TM-T70651

  • Aβ42 agonist-1
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    Aβ42 agonist-1

    CAS:
    <p>Aβ42 agonist-1 is a small molecule compound with anti-cancer activity and NF-κB inhibitory properties, inducing Aβ42 aggregation.</p>
    Formula:C15H11NO2
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:237.25

    Ref: TM-T85792

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    cSPM

    <p>cSPM (Cyclic spermine) is an Aβ42 inhibitor. cSPM inhibits the aggregation of three different peptides, Aβ42, tryptophan and insulin, and reduces cytotoxicity.</p>
    Formula:C27H57N7
    Color and Shape:Solid
    Molecular weight:479.79

    Ref: TM-T63163

  • UB 165
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    UB 165

    CAS:
    <p>Subtype-selective nicotinic agonist</p>
    Formula:C13H15ClN2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:234.72

    Ref: TM-T23485

  • DAPM
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    DAPM

    CAS:
    <p>DAPM (gamma-Secretase Inhibitor XVI) is a Notch pathway inhibitor with anticancer activity and antiproliferative effects.</p>
    Formula:C20H20F2N2O4
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:390.38

    Ref: TM-T86161

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    AChE-IN-24

    <p>AChE-IN-24: Strong AChE blocker, crosses blood-brain barrier, IC50=0.053 μM, useful for AD research.</p>
    Formula:C22H30N2O4S2
    Color and Shape:Solid
    Molecular weight:450.61

    Ref: TM-T62728

  • (-)-5-HT2C agonist-3
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    (-)-5-HT2C agonist-3

    CAS:
    <p>Compound (−)-19, also known as (-)-5-HT2C agonist-3, is a selective 5-HT2C agonist exhibiting a preference for Gq signaling. It demonstrates efficiency with EC50 values for 5-HT2 receptor subtypes as follows: 5-HT2C at 103 nM, 5-HT2B at 570 nM, and 5-HT2A at 72 nM. This compound is utilized in research on antipsychotics.</p>
    Formula:C19H23ClFNO2
    Color and Shape:Solid
    Molecular weight:351.84

    Ref: TM-T200458

  • DL-AP5 lithium
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    DL-AP5 lithium

    CAS:
    <p>DL-AP5 (2-APV) lithium is a competitive antagonist of the NMDA (N-Methyl-D-aspartate) receptor. It exhibits notable analgesic activity and specifically blocks channels in the rabbit retina.</p>
    Formula:C5H11LiNO5P
    Color and Shape:Solid
    Molecular weight:203.06

    Ref: TM-T201724

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    GABAA receptor agonist 1

    <p>Compound 3e, a potent GABAA agonist, targets GABA sites and has potential anti-depressive effects in mice.</p>
    Formula:C20H30O3
    Color and Shape:Solid
    Molecular weight:318.45

    Ref: TM-T60842

  • Tuclazepam
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    Tuclazepam

    CAS:
    <p>Tuclazepam (KC 1956) is a derivative of the benzodiazepine class of drugs, exhibiting anti-anxiety and sedative properties.</p>
    Formula:C17H16Cl2N2O
    Color and Shape:Solid
    Molecular weight:335.23

    Ref: TM-T201570

  • CVN636
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    CVN636

    CAS:
    <p>CVN636, a potent and selective allosteric agonist for the mGluR7 receptor, exhibits oral activity and CNS permeability [1], with an EC50 of 7 nM for human</p>
    Formula:C19H20FNO4S
    Color and Shape:Solid
    Molecular weight:377.43

    Ref: TM-T78090

  • AChE-IN-79
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    AChE-IN-79

    <p>AChE-IN-79 (compound 3i) is an acetylcholinesterase inhibitor with an IC50 of 2.7 µM, suitable for studies related to Alzheimer's disease.</p>
    Formula:C29H27NO6S
    Color and Shape:Solid
    Molecular weight:517.59

    Ref: TM-T201516

  • Tiprenolol hydrochloride
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    Tiprenolol hydrochloride

    CAS:
    <p>Tiprenolol hydrochloride is a β-adrenoceptor (β-adrenoceptor) antagonist. This compound is effective in eliminating ventricular arrhythmias in dogs caused by intravenous administration of adrenaline, following inhalation of halothane.</p>
    Formula:C13H22ClNO2S
    Color and Shape:Solid
    Molecular weight:291.84

    Ref: TM-T201760

  • P2X4 antagonist-1
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    P2X4 antagonist-1

    CAS:
    <p>P2X4 antagonist-1 is a potent P2X4 receptor antagonist used in the study of neurological, cardiovascular, and immune system diseases.</p>
    Formula:C20H15Cl3N2O4S
    Purity:99.9%
    Color and Shape:Solid
    Molecular weight:485.77

    Ref: TM-T87086

  • Zanapezil fumarate
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    Zanapezil fumarate

    CAS:
    <p>Zanapezil is an acetylcholinesterase (AChE) inhibitor. Zanapezil increases choline acetyltransferase activity in cultured rat septal cholinergic neurons.</p>
    Formula:C29H36N2O5
    Color and Shape:Solid
    Molecular weight:492.61

    Ref: TM-T29203

  • Dihydro-β-erythroidine
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    Dihydro-β-erythroidine

    CAS:
    <p>Dihydro-β-erythroidine, a competitive nicotinic receptor antagonist, effectively blocks the discriminative stimulus properties and inhibits the anxiolytic</p>
    Formula:C16H21NO3
    Color and Shape:Solid
    Molecular weight:275.34

    Ref: TM-T72382

  • (E)-CHBO4
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    (E)-CHBO4

    CAS:
    <p>(E)-CHBO4 is an MAO-B inhibitor with an IC50 value of 0.023 μM, making it a potential candidate for research into Parkinson's disease treatment.</p>
    Formula:C15H10BrFO
    Color and Shape:Solid
    Molecular weight:305.142

    Ref: TM-T204977

  • Antioxidant agent-8
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    Antioxidant agent-8

    <p>Antioxidant agent-8, an oral Aβ 1-42 inhibitor, reduces fibril aggregation &amp; promotes disaggregation; it's neuroprotective &amp; BBB permeable.</p>
    Formula:C13H12O5
    Color and Shape:Solid
    Molecular weight:248.23

    Ref: TM-T72506

  • Glutaminyl Cyclase Inhibitor 3
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    Glutaminyl Cyclase Inhibitor 3

    CAS:
    <p>Designed anti-Alzheimer’s compound; potent Glutaminyl Cyclase inhibitor; IC50 at 4.5 nM; reduces brain Aβ; improves cognition.</p>
    Formula:C24H32N6O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:468.61

    Ref: TM-T11422

  • LY2794193
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    LY2794193

    CAS:
    <p>LY2794193, a potent and selective mGlu3 receptor agonist, reduces akathisia seizures and increases GAT1, GLAST and GLT-1 protein levels in rats.</p>
    Formula:C16H18N2O6
    Purity:98.15%
    Color and Shape:Solid
    Molecular weight:334.32

    Ref: TM-T15807

  • SB 243213 hydrochloride
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    SB 243213 hydrochloride

    CAS:
    <p>SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8).It</p>
    Formula:C22H20ClF3N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:464.87

    Ref: TM-T12859

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    BChE-IN-2

    <p>BChE-IN-2, a pyrimidine/pyridine derivative, potently inhibits BChE (Ki 0.099 μM) and shows promise in AD research.</p>
    Formula:C22H31N5
    Color and Shape:Solid
    Molecular weight:365.52

    Ref: TM-T61408

  • LRRK2-IN-4
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    LRRK2-IN-4

    CAS:
    <p>LRRK2-IN-4: Potent, selective LRRK2 inhibitor, oral, BBB-penetrating, IC50=2.6 nM, potential for Parkinson's.</p>
    Formula:C25H29ClF2N6O2
    Color and Shape:Solid
    Molecular weight:518.99

    Ref: TM-T63621

  • Gabaculine HCl
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    Gabaculine HCl

    CAS:
    <p>Gabaculine, an irreversible GABA-T inhibitor (Ki: 2.9 μM), impacts plastid development and affects DPOR/GluTR levels.</p>
    Formula:C7H10ClNO2
    Color and Shape:Solid
    Molecular weight:175.61

    Ref: TM-T24080

  • BRD0418
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    BRD0418

    CAS:
    <p>BRD0418 acts as an upregulator of TRIB1 expression by leading to reprogramming of hepatic lipoprotein metabolism from adipogenesis to clearance it.</p>
    Formula:C29H32N2O5
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:488.57

    Ref: TM-T30577

  • hAChE/Aβ1-42-IN-1
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    hAChE/Aβ1-42-IN-1

    CAS:
    <p>Compound 16 (hAChE/Aβ1-42-IN-1) is a potent inhibitor targeting both hAChE and Aβ1-42 aggregation, demonstrating considerable safety in hepG2 cell lines and</p>
    Formula:C20H24N6O
    Color and Shape:Solid
    Molecular weight:364.44

    Ref: TM-T61388

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    CEase-IN-1

    <p>CEase-IN-1 (A1H3), potent CEase inhibitor, IC50 0.36μM, for hypercholesterolemia study.</p>
    Formula:C13H15F3N2O2
    Color and Shape:Solid
    Molecular weight:288.27

    Ref: TM-T60579

  • RO-1-5237
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    RO-1-5237

    CAS:
    <p>RO-1-5237, a cholinergic compound and a metabolic product of Pyridostigmine Bromide, is utilized in research for myasthenia gravis.</p>
    Formula:C6H8BrNO
    Color and Shape:Solid
    Molecular weight:190.04

    Ref: TM-T200816

  • CL-13
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    CL-13

    <p>CL-13 is an inhibitor of butyrylcholinesterase (BChE), exhibiting an IC50 of 1.15 μM and a selectivity index (SI) of 9.2 for acetylcholinesterase. It demonstrates antioxidative activity in SH-SY5Y cells with a DPPHEC50 of 47.01 μM and has the capacity to chelate metals involved in Aβ aggregation and/or oxidative stress, showing no neurotoxicity at concentrations up to 50 μM. CL-13 can also reverse scopolamine-induced cognitive impairments without affecting motor abilities in mice.</p>
    Formula:C29H32N4OS
    Color and Shape:Solid
    Molecular weight:484.66

    Ref: TM-T201512

  • VU6016235
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    VU6016235

    CAS:
    <p>VU6016235 is a structurally unique, orally available, and highly selective tricyclic M4 muscarinic acetylcholine receptor positive allosteric modulator.</p>
    Formula:C21H22N4OS
    Color and Shape:Solid
    Molecular weight:378.49

    Ref: TM-T201326

  • Serotonin maleate
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    Serotonin maleate

    CAS:
    <p>Serotonin hydrogen maleate serves as a monoaminergic neurotransmitter and an endogenous 5-HT receptor agonist within the central nervous system (CNS). It also functions as an inhibitor of catechol O-methyltransferase (COMT), exhibiting a Ki value of 44 μM.</p>
    Formula:C14H16N2O5
    Color and Shape:Solid
    Molecular weight:292.287

    Ref: TM-T204388

  • Poskine
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    Poskine

    CAS:
    <p>Poskine is an anticholinergic and central nervous system depressant. It is utilized in research related to Parkinson's disease and motion sickness.</p>
    Formula:C20H25NO5
    Color and Shape:Solid
    Molecular weight:359.42

    Ref: TM-T201100

  • R-137696
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    R-137696

    CAS:
    <p>R-137696 is an orally active 5-HT1A receptor agonist that facilitates the relaxation of the proximal stomach. It is utilized in research related to functional dyspepsia.</p>
    Formula:C17H23N3O2
    Color and Shape:Solid
    Molecular weight:301.38

    Ref: TM-T201501

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    (+)-Sparteine sulfate pentahydrate

    <p>(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.</p>
    Formula:C15H38N2O9S
    Color and Shape:Solid
    Molecular weight:422.54

    Ref: TM-T62265

  • LRRK2-IN-16
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    LRRK2-IN-16

    CAS:
    <p>LRRK2-IN-16 (compound 25) is an inhibitor of the LRRK2 kinase with an IC50 value of less than 5 μM. It is applicable for research in neurodegenerative and autoimmune diseases.</p>
    Formula:C18H19N5OS
    Color and Shape:Solid
    Molecular weight:353.441

    Ref: TM-T204380

  • 8 Hydroxy PIPAT oxalate
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    8 Hydroxy PIPAT oxalate

    CAS:
    <p>8 Hydroxy PIPAT oxalate is a selective 5-HT1A receptor agonist that enhances the spontaneous release of histamine by promoting the degranulation of mast cells in guinea pig and human intestinal preparations. By activating the serotonin signaling pathway, this compound demonstrates potential in regulating gastrointestinal functions and offers insight into the management and suppression of functional gastrointestinal disorders such as irritable bowel syndrome. Its effects in increasing histamine release could play a crucial role in gastrointestinal regulation.</p>
    Formula:C18H24INO5
    Color and Shape:Solid
    Molecular weight:461.29

    Ref: TM-T201052

  • DL-Thyroxine
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    DL-Thyroxine

    CAS:
    <p>DL-Thyroxine is a thyroid hormone that acts as a monoamine oxidase (monoamine oxidase) inhibitor.</p>
    Formula:C15H11I4NO4
    Color and Shape:Solid
    Molecular weight:776.87

    Ref: TM-T204436

  • MAO-B-IN-34
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    MAO-B-IN-34

    CAS:
    <p>MAO-B-IN-34 (compound 3d) is an inhibitor of monoamine oxidase B.</p>
    Formula:C15H9Cl2NO3
    Color and Shape:Solid
    Molecular weight:322.14

    Ref: TM-T200499

  • Fletazepam
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    Fletazepam

    CAS:
    <p>Fletazepam, a benzodiazepine derivative, exhibits sedative, anti-anxiety, and muscle-relaxant properties. It is utilized in neurological research.</p>
    Formula:C17H13ClF4N2
    Color and Shape:Solid
    Molecular weight:356.74

    Ref: TM-T201147

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    AAK1-IN-3 TFA

    <p>AAK1-IN-3 TFA, an AAK1 inhibitor with IC50 of 11 nM, crosses the blood-brain barrier, is a quinoline analogue, and may aid neuropathic pain research.</p>
    Formula:C24H22F6N4O4
    Color and Shape:Solid
    Molecular weight:544.45

    Ref: TM-T63834

  • LY3020371 hydrochloride
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    LY3020371 hydrochloride

    CAS:
    <p>LY3020371 HCl: potent mGlu2/3 antagonist, antidepressant-like; Ki: 5.3/2.5 nM, IC50: 16.2 nM for cAMP inhibition.</p>
    Formula:C15H16ClF2NO5S
    Color and Shape:Solid
    Molecular weight:395.81

    Ref: TM-T11911

  • LY 541850
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    LY 541850

    CAS:
    <p>LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from human</p>
    Formula:C9H13NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:199.2

    Ref: TM-T11906

  • Umibecestat
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    Umibecestat

    CAS:
    <p>Umibecestat inhibits human and mouse BACE-1 (IC50: 11 nM &amp; 10 nM), potentially for Alzheimer's research.</p>
    Formula:C19H15ClF7N5O2
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:513.8

    Ref: TM-T13253