
Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(942 products)
- ACK(1 products)
- AChR(575 products)
- ATP Citrate Lyase(16 products)
- Adrenergic Receptor(2,948 products)
- BACE(36 products)
- Beta Amyloid(205 products)
- CaMK(69 products)
- Cyclooxygenase (COX) Inhibitors(565 products)
- Dopamine Receptor(409 products)
- GABA Receptor(336 products)
- Gamma-secretase(59 products)
- GluR(255 products)
- GlyT(24 products)
- Histamine Receptor(359 products)
- LRRK2(33 products)
- Melatonin Receptor(24 products)
- NMDAR(27 products)
- OX Receptor(40 products)
- Opioid Receptor(298 products)
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Found 5390 products of "Neuroscience"
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2'-O-Succinyl-cAMP
CAS:<p>2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate is an immunogenic derivative of cAMP that has been used to generate anti-cAMP antisera and antibodies.1,2</p>Formula:C14H16N5O9PColor and Shape:SolidMolecular weight:429.282YS-370
CAS:<p>YS-370 orally blocks P-gp, moderately inhibits CYP3A4, reverses drug resistance, and enhances paclitaxel's anticancer effects.</p>Formula:C37H35BrN4O3Purity:98.055%Color and Shape:SolidMolecular weight:663.6BuChE-IN-16
<p>BuChE-IN-16 (Compound 6a) is an orally active, blood-brain barrier-permeable, and selective BuChE inhibitor with an IC50 of 0.33 μM. It exhibits anti-inflammatory and neuroprotective effects, improves cognitive function in Alzheimer's disease (AD) zebrafish models, and alleviates scopolamine-induced memory impairment in mice. BuChE-IN-16 is applicable for Alzheimer's disease research.</p>Formula:C16H22N2O3Color and Shape:SolidMolecular weight:290.36Brexpiprazole S-oxide D8
CAS:<p>Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.</p>Formula:C25H19D8N3O3SPurity:98%Color and Shape:SolidMolecular weight:457.61β-Amyloid (35-42)
CAS:<p>β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.</p>Formula:C33H60N8O9SPurity:98%Color and Shape:SolidMolecular weight:744.94I2-IRs ligand-1
<p>I2-IRs ligand-1 (Compound 12d) is an orally active compound capable of crossing the blood-brain barrier. It exhibits high affinity for imidazoline I2 receptors (I2-IRs) with a pKi of 9.98. This compound can enhance cognitive deficits in aging mice and possesses analgesic, anti-inflammatory, and neuroprotective properties. I2-IRs ligand-1 is applicable for research in Alzheimer's disease and related pain disorders.</p>Formula:C21H23ClFN2O4PColor and Shape:SolidMolecular weight:452.84α5-GABAA receptor modulator 1
<p>α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.</p>Formula:C21H20FN3O4Color and Shape:SolidMolecular weight:397.4Vortioxetine D8
CAS:<p>Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).</p>Formula:C18H22N2SPurity:98%Color and Shape:SolidMolecular weight:306.5Anticonvulsant agent 8
<p>Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.</p>Formula:C15H11N5OColor and Shape:SolidMolecular weight:277.285-HT6R antagonist 6
<p>5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.</p>Formula:C24H26N4O2SColor and Shape:SolidMolecular weight:434.55Rasagiline 13C3 mesylate racemic
CAS:<p>Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.</p>Formula:C13H17NO3SPurity:98%Color and Shape:SolidMolecular weight:270.32N-Ethyl-N-(3-pyridylmethyl)amine
CAS:<p>N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.</p>Formula:C8H12N2Purity:99.65%Color and Shape:SolidMolecular weight:136.19SSAO inhibitor-1
CAS:<p>SSAO Inhibitor-1 blocks SSAO, has anti-inflammatory effects, used in liver disease research.</p>Formula:C17H24FN5O2Color and Shape:SolidMolecular weight:349.41β-Amyloid (12-28)
CAS:<p>Amyloid β-peptide fragment; minimum section required to bind to brain proteins.</p>Formula:C89H135N25O25Purity:98%Color and Shape:SolidMolecular weight:1955.18epi-Aszonalenin A
CAS:<p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>Formula:C25H25N3O3Color and Shape:SolidMolecular weight:415.48OXA(17-33)
CAS:Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.Formula:C79H125N23O22Purity:98%Color and Shape:SolidMolecular weight:1749RA306
<p>RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.</p>Color and Shape:Odour SolidFluphenazine-N-2-chloroethane (hydrochloride)
CAS:<p>Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.</p>Formula:C22H27Cl3F3N3SColor and Shape:SolidMolecular weight:528.89Laniquidar TFA
<p>Laniquidar TFA (R101933), a non-competitive P-gp inhibitor, has an IC50 of 0.51 μM; used to study AML and MDS, but with limited bioavailability.</p>Formula:C39H37F3N4O5Purity:99.85%Color and Shape:SoildMolecular weight:698.73Sulamserod
CAS:<p>Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular related</p>Formula:C19H28ClN3O5SPurity:98.76%Color and Shape:SolidMolecular weight:445.96Eletriptan
CAS:<p>Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.</p>Formula:C22H26N2O2SColor and Shape:SolidMolecular weight:382.52Nitrazolam
CAS:<p>Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.</p>Formula:C17H13N5O2Color and Shape:SolidMolecular weight:319.32Atagabalin
CAS:<p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>Formula:C10H19NO2Color and Shape:SolidMolecular weight:185.26Fasciculic acid C
CAS:<p>Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.</p>Formula:C38H63NO11Purity:98%Color and Shape:SolidMolecular weight:709.91β-Amyloid (4-10)
CAS:Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances inFormula:C39H52N12O12Purity:98%Color and Shape:SolidMolecular weight:880.9AChE-IN-40
<p>AChE-IN-40 (Compound 5C), with an inhibitory concentration 50 (IC50) of 120 nM, is an acetylcholinesterase (AChE) inhibitor suitable for Alzheimer's disease</p>Formula:C23H27NO4Color and Shape:SolidMolecular weight:381.46N-Desmethyl Pimavanserin
CAS:<p>N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.</p>Formula:C24H32FN3O2Purity:98.02%Color and Shape:SolidMolecular weight:413.53Moxonidine hydrochloride
CAS:<p>Moxonidine Hydrochloride: selective I1 imidazoline receptor agonist, stronger than α2-AR; lowers blood pressure; central action.</p>Formula:C9H13Cl2N5OColor and Shape:SolidMolecular weight:278.14(R)-Citalopram oxalate
CAS:<p>(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant</p>Formula:C22H23FN2O5Purity:99.76%Color and Shape:White SolidMolecular weight:414.43β-Amyloid (22-35)
CAS:<p>β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells.</p>Formula:C59H102N16O21SPurity:98%Color and Shape:SolidMolecular weight:1403.62LY-426965 hydrochloride
CAS:LY-426965 hydrochloride is a bioactive chemical.Formula:C28H39ClN2O2Color and Shape:SolidMolecular weight:471.07Blestrin D
CAS:<p>Blestrin D: BChE mixed-type inhibitor, IC50=8.1μM, from Bletilla striata, for AD research.</p>Formula:C30H24O6Color and Shape:SolidMolecular weight:480.51Jatrorrhizine hydroxide
CAS:<p>Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.</p>Formula:C20H21NO5Color and Shape:SolidMolecular weight:355.38Zicronapine fumarate
CAS:<p>Zicronapine fumarate, an antipsychotic, targets D1/D2 & 5-HT2A receptors; may treat neuropsychiatric conditions.</p>Formula:C26H31ClN2O4Color and Shape:SolidMolecular weight:470.99Polyglutamine binding peptide 1
CAS:<p>Polyglutamine binding peptide 1 (QBP1) is a peptide inhibitor of polyglutamine (polyQ). It effectively inhibits polyQ protein aggregation in vitro and prevents polyQ-induced cell death in cell cultures.</p>Formula:C72H90N16O16Color and Shape:SolidMolecular weight:1435.58Paynantheine
CAS:<p>Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.</p>Formula:C23H28N2O4Color and Shape:SolidMolecular weight:396.48Endosulfan I
CAS:<p>Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complex</p>Formula:C9H6Cl6O3SPurity:99.86%Color and Shape:SolidMolecular weight:406.93L-689560
CAS:<p>L-689560, a radiolabeled ligand, studies NMDA receptors, is an antagonist at GluN1 glycine site.</p>Formula:C17H15Cl2N3O3Purity:98%Color and Shape:SolidMolecular weight:380.235H-Pyrido[4,3-b]indole
CAS:<p>5H-Pyrido[4,3-b]indole is a potential AchE/ChE inhibitor with potential antiviral activity for the study of neurodegenerative diseases.</p>Formula:C11H8N2Purity:99.6%Color and Shape:SolidMolecular weight:168.2JF-NP-26
<p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>Color and Shape:SolidNardoguaianone J
CAS:<p>Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].</p>Formula:C15H22O2Color and Shape:SolidMolecular weight:234.33UCM 549
CAS:<p>UCM 549 is a bioactive chemical.</p>Formula:C19H21NO2Color and Shape:SolidMolecular weight:295.38SB656104
CAS:<p>SB656104 is a bioactive chemical.</p>Formula:C25H30ClN3O3SColor and Shape:SolidMolecular weight:488.04α-Conotoxin imi
CAS:alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.Formula:C52H78N20O15S4Purity:98%Color and Shape:SolidMolecular weight:1351.56Alosetron
CAS:<p>Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.</p>Formula:C17H18N4OPurity:98%Color and Shape:Crystalline PowderMolecular weight:294.36LY 293284
CAS:<p>LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.</p>Formula:C19H26N2OColor and Shape:SolidMolecular weight:298.42(Iso)-Landipirdine
CAS:<p>(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.</p>Formula:C18H19FN2O3SPurity:98.50%Color and Shape:SoildMolecular weight:362.42Flupyradifurone
CAS:<p>Flupyradifurone (flupyradifurone) is a systemic insecticide and nicotinic acetylcholine receptor (nAChR) agonist interfer nervous system of insects.</p>Formula:C12H11ClF2N2O2Purity:99.83%Color and Shape:SolidMolecular weight:288.68AL 34662
CAS:<p>AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also a</p>Formula:C10H13N3OPurity:99.77%Color and Shape:SolidMolecular weight:191.23P-gb-IN-1
CAS:<p>P-gb-IN-1 is a potent P-glycoprotein (P-gp) inhibitor that exhibits reverse activity by inhibiting P-gp outflow.</p>Formula:C30H28N2O6Purity:99.58%Color and Shape:SoildMolecular weight:512.55

