CymitQuimica logo
Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

Show 12 more subcategories

Found 5390 products of "Neuroscience"

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • 2'-O-Succinyl-cAMP

    CAS:
    <p>2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate is an immunogenic derivative of cAMP that has been used to generate anti-cAMP antisera and antibodies.1,2</p>
    Formula:C14H16N5O9P
    Color and Shape:Solid
    Molecular weight:429.282
  • YS-370

    CAS:
    <p>YS-370 orally blocks P-gp, moderately inhibits CYP3A4, reverses drug resistance, and enhances paclitaxel's anticancer effects.</p>
    Formula:C37H35BrN4O3
    Purity:98.055%
    Color and Shape:Solid
    Molecular weight:663.6
  • BuChE-IN-16


    <p>BuChE-IN-16 (Compound 6a) is an orally active, blood-brain barrier-permeable, and selective BuChE inhibitor with an IC50 of 0.33 μM. It exhibits anti-inflammatory and neuroprotective effects, improves cognitive function in Alzheimer's disease (AD) zebrafish models, and alleviates scopolamine-induced memory impairment in mice. BuChE-IN-16 is applicable for Alzheimer's disease research.</p>
    Formula:C16H22N2O3
    Color and Shape:Solid
    Molecular weight:290.36
  • Brexpiprazole S-oxide D8

    CAS:
    <p>Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.</p>
    Formula:C25H19D8N3O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:457.61
  • β-Amyloid (35-42)

    CAS:
    <p>β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.</p>
    Formula:C33H60N8O9S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:744.94
  • I2-IRs ligand-1


    <p>I2-IRs ligand-1 (Compound 12d) is an orally active compound capable of crossing the blood-brain barrier. It exhibits high affinity for imidazoline I2 receptors (I2-IRs) with a pKi of 9.98. This compound can enhance cognitive deficits in aging mice and possesses analgesic, anti-inflammatory, and neuroprotective properties. I2-IRs ligand-1 is applicable for research in Alzheimer's disease and related pain disorders.</p>
    Formula:C21H23ClFN2O4P
    Color and Shape:Solid
    Molecular weight:452.84
  • α5-GABAA receptor modulator 1


    <p>α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.</p>
    Formula:C21H20FN3O4
    Color and Shape:Solid
    Molecular weight:397.4
  • Vortioxetine D8

    CAS:
    <p>Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors &amp; SERT (Ki: 15-1.6 nM).</p>
    Formula:C18H22N2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:306.5
  • Anticonvulsant agent 8


    <p>Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.</p>
    Formula:C15H11N5O
    Color and Shape:Solid
    Molecular weight:277.28
  • 5-HT6R antagonist 6


    <p>5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.</p>
    Formula:C24H26N4O2S
    Color and Shape:Solid
    Molecular weight:434.55
  • Rasagiline 13C3 mesylate racemic

    CAS:
    <p>Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.</p>
    Formula:C13H17NO3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:270.32
  • N-Ethyl-N-(3-pyridylmethyl)amine

    CAS:
    <p>N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.</p>
    Formula:C8H12N2
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:136.19
  • SSAO inhibitor-1

    CAS:
    <p>SSAO Inhibitor-1 blocks SSAO, has anti-inflammatory effects, used in liver disease research.</p>
    Formula:C17H24FN5O2
    Color and Shape:Solid
    Molecular weight:349.41
  • β-Amyloid (12-28)

    CAS:
    <p>Amyloid β-peptide fragment; minimum section required to bind to brain proteins.</p>
    Formula:C89H135N25O25
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1955.18
  • epi-Aszonalenin A

    CAS:
    <p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>
    Formula:C25H25N3O3
    Color and Shape:Solid
    Molecular weight:415.48
  • OXA(17-33)

    CAS:
    Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.
    Formula:C79H125N23O22
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1749
  • RA306


    <p>RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.</p>
    Color and Shape:Odour Solid
  • Fluphenazine-N-2-chloroethane (hydrochloride)

    CAS:
    <p>Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.</p>
    Formula:C22H27Cl3F3N3S
    Color and Shape:Solid
    Molecular weight:528.89
  • Laniquidar TFA


    <p>Laniquidar TFA (R101933), a non-competitive P-gp inhibitor, has an IC50 of 0.51 μM; used to study AML and MDS, but with limited bioavailability.</p>
    Formula:C39H37F3N4O5
    Purity:99.85%
    Color and Shape:Soild
    Molecular weight:698.73
  • Sulamserod

    CAS:
    <p>Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular related</p>
    Formula:C19H28ClN3O5S
    Purity:98.76%
    Color and Shape:Solid
    Molecular weight:445.96
  • Eletriptan

    CAS:
    <p>Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.</p>
    Formula:C22H26N2O2S
    Color and Shape:Solid
    Molecular weight:382.52
  • Nitrazolam

    CAS:
    <p>Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.</p>
    Formula:C17H13N5O2
    Color and Shape:Solid
    Molecular weight:319.32
  • Atagabalin

    CAS:
    <p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>
    Formula:C10H19NO2
    Color and Shape:Solid
    Molecular weight:185.26
  • Fasciculic acid C

    CAS:
    <p>Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.</p>
    Formula:C38H63NO11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:709.91
  • β-Amyloid (4-10)

    CAS:
    Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances in
    Formula:C39H52N12O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:880.9
  • AChE-IN-40


    <p>AChE-IN-40 (Compound 5C), with an inhibitory concentration 50 (IC50) of 120 nM, is an acetylcholinesterase (AChE) inhibitor suitable for Alzheimer's disease</p>
    Formula:C23H27NO4
    Color and Shape:Solid
    Molecular weight:381.46
  • N-Desmethyl Pimavanserin

    CAS:
    <p>N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.</p>
    Formula:C24H32FN3O2
    Purity:98.02%
    Color and Shape:Solid
    Molecular weight:413.53
  • Moxonidine hydrochloride

    CAS:
    <p>Moxonidine Hydrochloride: selective I1 imidazoline receptor agonist, stronger than α2-AR; lowers blood pressure; central action.</p>
    Formula:C9H13Cl2N5O
    Color and Shape:Solid
    Molecular weight:278.14
  • (R)-Citalopram oxalate

    CAS:
    <p>(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant</p>
    Formula:C22H23FN2O5
    Purity:99.76%
    Color and Shape:White Solid
    Molecular weight:414.43
  • β-Amyloid (22-35)

    CAS:
    <p>β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells.</p>
    Formula:C59H102N16O21S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1403.62
  • LY-426965 hydrochloride

    CAS:
    LY-426965 hydrochloride is a bioactive chemical.
    Formula:C28H39ClN2O2
    Color and Shape:Solid
    Molecular weight:471.07
  • Blestrin D

    CAS:
    <p>Blestrin D: BChE mixed-type inhibitor, IC50=8.1μM, from Bletilla striata, for AD research.</p>
    Formula:C30H24O6
    Color and Shape:Solid
    Molecular weight:480.51
  • Jatrorrhizine hydroxide

    CAS:
    <p>Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.</p>
    Formula:C20H21NO5
    Color and Shape:Solid
    Molecular weight:355.38
  • Zicronapine fumarate

    CAS:
    <p>Zicronapine fumarate, an antipsychotic, targets D1/D2 &amp; 5-HT2A receptors; may treat neuropsychiatric conditions.</p>
    Formula:C26H31ClN2O4
    Color and Shape:Solid
    Molecular weight:470.99
  • Polyglutamine binding peptide 1

    CAS:
    <p>Polyglutamine binding peptide 1 (QBP1) is a peptide inhibitor of polyglutamine (polyQ). It effectively inhibits polyQ protein aggregation in vitro and prevents polyQ-induced cell death in cell cultures.</p>
    Formula:C72H90N16O16
    Color and Shape:Solid
    Molecular weight:1435.58
  • Paynantheine

    CAS:
    <p>Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.</p>
    Formula:C23H28N2O4
    Color and Shape:Solid
    Molecular weight:396.48
  • Endosulfan I

    CAS:
    <p>Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complex</p>
    Formula:C9H6Cl6O3S
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:406.93
  • L-689560

    CAS:
    <p>L-689560, a radiolabeled ligand, studies NMDA receptors, is an antagonist at GluN1 glycine site.</p>
    Formula:C17H15Cl2N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:380.23
  • 5H-Pyrido[4,3-b]indole

    CAS:
    <p>5H-Pyrido[4,3-b]indole is a potential AchE/ChE inhibitor with potential antiviral activity for the study of neurodegenerative diseases.</p>
    Formula:C11H8N2
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:168.2
  • JF-NP-26


    <p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>
    Color and Shape:Solid
  • Nardoguaianone J

    CAS:
    <p>Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].</p>
    Formula:C15H22O2
    Color and Shape:Solid
    Molecular weight:234.33
  • UCM 549

    CAS:
    <p>UCM 549 is a bioactive chemical.</p>
    Formula:C19H21NO2
    Color and Shape:Solid
    Molecular weight:295.38
  • SB656104

    CAS:
    <p>SB656104 is a bioactive chemical.</p>
    Formula:C25H30ClN3O3S
    Color and Shape:Solid
    Molecular weight:488.04
  • α-Conotoxin imi

    CAS:
    alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.
    Formula:C52H78N20O15S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1351.56
  • Alosetron

    CAS:
    <p>Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.</p>
    Formula:C17H18N4O
    Purity:98%
    Color and Shape:Crystalline Powder
    Molecular weight:294.36
  • LY 293284

    CAS:
    <p>LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.</p>
    Formula:C19H26N2O
    Color and Shape:Solid
    Molecular weight:298.42
  • (Iso)-Landipirdine

    CAS:
    <p>(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.</p>
    Formula:C18H19FN2O3S
    Purity:98.50%
    Color and Shape:Soild
    Molecular weight:362.42
  • Flupyradifurone

    CAS:
    <p>Flupyradifurone (flupyradifurone) is a systemic insecticide and nicotinic acetylcholine receptor (nAChR) agonist interfer nervous system of insects.</p>
    Formula:C12H11ClF2N2O2
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:288.68
  • AL 34662

    CAS:
    <p>AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also a</p>
    Formula:C10H13N3O
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:191.23
  • P-gb-IN-1

    CAS:
    <p>P-gb-IN-1 is a potent P-glycoprotein (P-gp) inhibitor that exhibits reverse activity by inhibiting P-gp outflow.</p>
    Formula:C30H28N2O6
    Purity:99.58%
    Color and Shape:Soild
    Molecular weight:512.55