Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(1,025 products)
- ACK(1 products)
- AChR(645 products)
- ATP Citrate Lyase(17 products)
- Adrenergic Receptor(3,018 products)
- BACE(37 products)
- Beta Amyloid(228 products)
- CaMK(73 products)
- Cyclooxygenase (COX) Inhibitors(600 products)
- Dopamine Receptor(445 products)
- GABA Receptor(372 products)
- Gamma-secretase(61 products)
- GluR(265 products)
- GlyT(26 products)
- Histamine Receptor(385 products)
- LRRK2(43 products)
- Melatonin Receptor(26 products)
- NMDAR(10 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
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Found 5530 products of "Neuroscience"
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Notch 1
CAS:Notch1 (Notchhomolog 1, translocation-associated) encodes a protein that is a member of the NOTCH family. This type I transmembrane protein family is characterized by common structural features, including an extracellular domain made up of multiple epidermal growth factor-like (EGF) repeats and an intracellular domain composed of various types of domains.Formula:C62H97N15O22S3Color and Shape:SolidMolecular weight:1500.72meta-Fluoxetine (hydrochloride)
CAS:meta-Fluoxetine (hydrochloride) can be used in related research in the field of life sciences. Its product number is T37474 and CAS number is 79088-29-2.Formula:C17H19ClF3NOColor and Shape:SolidMolecular weight:345.79HTR2A antagonist 1
HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.Formula:C35H43Cl2F2N5O4Color and Shape:SolidMolecular weight:706.65SAHM1 TFA
SAHM1 TFA inhibits the Notch pathway, stabilizes alpha helices, and blocks Notch complex formation.Formula:C96H163N36F3O25SColor and Shape:SolidMolecular weight:2310.6MRS7925
MRS7925 (Compound 43) serves as a potent antagonist of the 5-HT2B receptor, with an inhibition constant (Ki) of 17 nM, and is utilized in the study of fibrosisFormula:C20H26IN5O3Purity:98%Color and Shape:SolidMolecular weight:511.36MAO-B-IN-25
MAO-B-IN-25 (compound 92) is a selective inhibitor of monoamine oxidase B (MAO-B), exhibiting inhibitory half-maximal inhibitory concentrations (IC50) of 240 nMFormula:C16H13BrO3Purity:98%Color and Shape:SolidMolecular weight:333.18LY3020371
CAS:LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.Formula:C15H15F2NO5SColor and Shape:SolidMolecular weight:359.34Arotinolol hydrochloride
CAS:Arotinolol HCl is a non-selective α/β-blocker, anti-hypertensive, anti-obesity, and improves aortic stiffness.Formula:C15H22ClN3O2S3Purity:99.82%Color and Shape:SolidMolecular weight:408S-8510 free base
CAS:S-8510 is a GABA-A receptor inverse agonist enhancing memory, LTP, and neurotransmitters in rats.Formula:C12H10N4O2Color and Shape:SolidMolecular weight:242.23(-)-Eseroline fumarate
CAS:(-)-Eseroline fumarate, a Physostigmine metabolite and AChE inhibitor, triggers cancer cell LDH release and neuronal cell death.Formula:C17H22N2O5Color and Shape:SolidMolecular weight:334.37Bis-(-)-8-demethylmaritidine
Bis-(-)-8-demethylmaritidine, a natural alkaloid, serves as a potent inhibitor of acetylcholinesterase (AChE) and is utilized in Alzheimer's disease research [1Color and Shape:Odour SolidCVN417
CVN417 is an orally active antagonist of nAChR containing the α6 subunit, modulating phasic dopaminergic neurotransmission in an impulse-dependent fashion.Color and Shape:Odour SolidM1/M4 muscarinic agonist 2
Compound 40 is a selective M1/M4 muscarinic antagonist with an IC50 of 19 nM for M1 receptors and 42 nM for M4 receptors [1].Color and Shape:Odour SolidRivanicline 2HCl
Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype.Formula:C10H16Cl2N2Purity:99.4%Color and Shape:SoildMolecular weight:235.15Ref: TM-T12738L1
1mg34.00€5mg71.00€10mg100.00€25mg234.00€50mg420.00€100mg617.00€1mL*10mM (DMSO)110.00€Ro60-0175
CAS:Ro60-0175 is a selective 5-HT2B and 5-HT2C serotonin receptor agonist, often used as fumarate.Formula:C11H12ClFN2Purity:97.09%Color and Shape:SolidMolecular weight:226.68Ref: TM-T39161
1mg93.00€5mg205.00€10mg334.00€25mg587.00€50mg802.00€100mg1,108.00€1mL*10mM (DMSO)187.00€Riluzole-13C,15N2
CAS:Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.Formula:CC7H5F3OS15N2Color and Shape:SolidMolecular weight:237.18(±)-Coniine
CAS:(±)-Coniine, a piperidine alkaloid, is a toxin found in poison hemlock.Formula:C8H17NColor and Shape:SolidMolecular weight:127.23U92016A
CAS:U92016A is a highly potent and selective agonist of 5-HT1A receptor.Formula:C19H25N3Purity:98%Color and Shape:SolidMolecular weight:295.42Profenofos
CAS:Profenofos is an organophosphate insecticide used in cotton and vegetables. that causes neurotoxicity through the inhibition of AChE activity.Formula:C11H15BrClO3PSPurity:97.04% - 97.24%Color and Shape:SolidMolecular weight:373.63[Ala2,8,9,11,19,22,24,25,27,28]-VIP
CAS:[Ala2,8,9,11,19,22,24,25,27,28]-VIP can be used for related research in the field of life sciences. Its product number is T36637 and CAS number is 866552-34-3.Formula:C131H219N41O33SColor and Shape:SolidMolecular weight:2928.51E3 ligase Ligand 41
CAS:E3 Ligase Ligand 41 (Compound SI-13) serves as a ligand for the E3 ubiquitin ligase DCAF16. It is designed to connect with SLF through a linker, enabling the formation of KB03-SLF.Formula:C13H12ClF3N2O4Color and Shape:SolidMolecular weight:352.69GABA-IN-1
GABA-IN-1 (Compound 6), a GABA inhibitor, exhibits larvicidal and insecticidal properties, achieving a mortality rate of 93% at a concentration of 50 mg/L [1].Color and Shape:Odour SolidTC-2216
CAS:TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.Formula:C12H17N3Purity:99.81%Color and Shape:SolidMolecular weight:203.28RN277
RN277 is an inhibitor of LRRK2 type II kinase (LRRK2type II kinase). It serves as a cellular tool targeting the inactive state of LRRK2. In vitro, RN277 inhibits LRRK1 kinase activity and the kinase activity of LRRK2, with an IC50 of 70 nM. Additionally, it reduces Rab8a phosphorylation in a dose-dependent manner. RN277 is useful for Parkinson's disease research.Color and Shape:Odour SolidPalonosetron N-oxide
CAS:Palonosetron N-oxide: metabolite and potential impurity of 5-HT3 antagonist palonosetron; forms under oxidative stress.Formula:C19H24N2O2Color and Shape:SolidMolecular weight:312.413Aβ-IN-7
Aβ-IN-7 (compound 5a) acts as a potent inhibitor of Aβ aggregation, stabilizing Aβ monomers at 50 μM concentration to prevent them from forming larger oligomersFormula:C14H10N2SColor and Shape:SolidMolecular weight:238.31LY 344864 racemate
CAS:LY 344864 racemate is a 5-HT1F receptor agonist.Formula:C21H22FN3OPurity:99.75%Color and Shape:SoildMolecular weight:351.42AAK1-IN-11
AAK1-IN-11 is an inhibitor of AAK1 (adaptor associated kinase 1) with an IC50 of 2 nM, and it exhibits antiviral activity.Color and Shape:Odour Solid(-)-2-Phenylpropylamine
CAS:(-)-2-Phenylpropylamine ((S)-2-Phenylpropylamine) (compound 3b) functions as an inhibitor for both MAO-A and MAO-B, with Ki values of 584 μM and 156 μM, respectively.Formula:C9H13NColor and Shape:SolidMolecular weight:135.21Aβ-IN-8
Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].Formula:C22H16F3N3O3SColor and Shape:SolidMolecular weight:459.44LP-20
CAS:LP-20 is a bioactive chemical.Formula:C17H20N2OColor and Shape:SolidMolecular weight:268.35SLAFVDVLN
SLAFVDVLN is a peptide molecule that functions as a BACE-1 inhibitor, exhibiting a Ki value of 94 nM. Additionally, SLAFVDVLN is capable of reducing the production of Aβ42.Formula:C45H72N10O14Color and Shape:SolidMolecular weight:977.11Pyrantel hydrochloride
CAS:Pyrantel hydrochloride is the hydrochloride form of Pyrantel. Pyrantel is is an anthelmintic and a nicotinic acetylcholine receptor (nAChR) agonist.Formula:C11H15ClN2SPurity:98.01%Color and Shape:SoildMolecular weight:242.77Pridinol hydrochloride
CAS:Pridinolhydrochloride is the hydrochloride form of Pridinol. Pridinol hydrochloride is an orally active anticholinergic agent, which can also be used as a muscle relaxant.Formula:C20H26ClNOColor and Shape:SolidMolecular weight:331.88hAChE/hBuChE/GSK-3β-IN-1
hAChE/hBuChE/GSK-3β-IN-1 (Compound 6c) is a multi-target compound designed for Alzheimer's treatment capable of crossing the blood-brain barrier. It inhibits hAChE with an IC50 of 28.88 nM, hBuChE with an IC50 of 131.90 nM, and GSK-3β with an IC50 of 51.42 nM. Additionally, it acts as an inhibitor of tau protein and Aβ protein aggregation.Formula:C19H15NO4Color and Shape:SolidMolecular weight:321.3272-APB hydrochloride
CAS:2-APB is an analog of 6-APB and falls under the category of benzofuran derivatives, known for its psychoactive properties. Certain benzofuran derivatives also exhibit monoamine oxidase-A (MAO-A) inhibitory activity.Formula:C11H14ClNOColor and Shape:SolidMolecular weight:211.69SB 258585
CAS:SB 258585: Selective 5-HT6 antagonist, binds human receptors, used in cognitive and antipsychotic assays.Formula:C18H22IN3O3SPurity:99.77%Color and Shape:SoildMolecular weight:487.36AChE/BuChE/MAO-B-IN-2
AChE/BuChE/MAO-B-IN-2 (compound 4b) is a potent inhibitor of AChE, BuChE, and hu MAO-B, with respective IC50 values of 5.3 μM, 12.4 μM, and 1.9±0.08 μM,Formula:C19H18FNO3Color and Shape:SolidMolecular weight:327.35PSEM 308 hydrochloride
PSAM agonist targeting PSAML141F-GlyR and related ion channels in mice; ideal concentration ≤5 mg/kg; plasmids at Addgene.Color and Shape:Solid5-HT2A receptor agonist-6
CAS:5-HT2A receptor agonist-6 (compound 47) is a selective agonist of the 5-HT2A receptor with a pEC50 value of 6.58.Formula:C18H19N3O3Color and Shape:SolidMolecular weight:325.363-Chloroamphetamine hydrochloride
CAS:3-Chloroamphetamine hydrochloride is a derivative of amphetamine that acts as a central nervous system stimulant by releasing serotonin and dopamine.Formula:C9H13Cl2NColor and Shape:SolidMolecular weight:206.11DISC-0974
DISC-0974 is a humanized antibody targeting RGMC/HFE2, which can be used to study urogenital system diseases.Color and Shape:LiquidMolecular weight:145.66 kDaMerinetug
CAS:Merinetug is a humanized IgG1κ antibody that targets Amyloid Beta (Aβ). Its corresponding isotype control is Human IgG1 kappa, Isotype Control.Color and Shape:LiquidLon 954
CAS:Lon 954, also known as Harmine, is a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds.Formula:C9H10Cl3N3OColor and Shape:SolidMolecular weight:282.55Pyrazolam
CAS:Pyrazolam is a psychoactive benzodiazepine compound serving as a central nervous system depressant. [Pyrazolam] can lead to psychomotor impairment.Formula:C16H12BrN5Color and Shape:SolidMolecular weight:354.2Dalidnetug
CAS:Dalidnetug is a humanized monoclonal antibody that targets human β-amyloid precursor protein (APP). By specifically binding to APP, Dalidnetug reduces the production of β-amyloid (Aβ), thereby demonstrating activity in clearing β-amyloid. This compound holds potential for research in Alzheimer's disease.Color and Shape:LiquidMaesopsin
Maesopsin is a useful organic compound for research related to life sciences and the catalog number is T124581.Formula:C15H12O6Color and Shape:SolidMolecular weight:288.255BRD9 ligand-6
CAS:BRD9 ligand-6 serves as a ligand for the target protein in PROTAC applications. It is utilized in the synthesis of FHD-609.Formula:C21H21N3O4Color and Shape:SolidMolecular weight:379.41Vanutide cridificar
CAS:Vanutide cridificar (ACC-001) is an aminoterminal Aβ1-7 peptide conjugate, employed in Alzheimer’s disease (AD) research [1].Color and Shape:Liquid2,6-DMA hydrochloride
CAS:2,6-DMA hydrochloride is a phenethylamine and acts as an agonist of the serotonin 5-HT2 receptor, with a pA2 value of 5.09.Formula:C11H18ClNO2Color and Shape:SolidMolecular weight:231.72
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