Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(1,025 products)
- ACK(1 products)
- AChR(645 products)
- ATP Citrate Lyase(17 products)
- Adrenergic Receptor(3,018 products)
- BACE(37 products)
- Beta Amyloid(228 products)
- CaMK(73 products)
- Cyclooxygenase (COX) Inhibitors(600 products)
- Dopamine Receptor(445 products)
- GABA Receptor(372 products)
- Gamma-secretase(61 products)
- GluR(265 products)
- GlyT(26 products)
- Histamine Receptor(385 products)
- LRRK2(43 products)
- Melatonin Receptor(26 products)
- NMDAR(10 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
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Found 5500 products of "Neuroscience"
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TC-2216
CAS:TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.Formula:C12H17N3Purity:99.81%Color and Shape:SolidMolecular weight:203.28Profenofos
CAS:Profenofos is an organophosphate insecticide used in cotton and vegetables. that causes neurotoxicity through the inhibition of AChE activity.Formula:C11H15BrClO3PSPurity:97.04% - 97.24%Color and Shape:SolidMolecular weight:373.63NMDA receptor antagonist 6
NMDA Receptor Antagonist 6 (Compound 13b) functions as an antagonist at the glycine-binding site of the NMDA receptor and demonstrates cytoneuroprotectiveFormula:C25H23NO2Purity:98%Color and Shape:SolidMolecular weight:369.46Lysyl hydroxylase 2-IN-2
Lysyl Hydroxylase 2-IN-2 (compound 13) is a potent inhibitor of Lysyl Hydroxylase 2 (LH2), exhibiting an IC50 of approximately 500 nM.Formula:C19H21N3O2Purity:98%Color and Shape:SolidMolecular weight:323.39MmTx2 toxin
MmTx2 toxin, extracted from the venom of the coral snake, serves as a modulator of the GABA A receptor, increasing its responsiveness to agonists.Formula:C295H450N94O97S10Purity:98%Color and Shape:SolidMolecular weight:7185.95Methyl piperate
CAS:Methylpiperic acid, a piperine alkaloid, exhibits potent inhibitory activity on monoamine oxidase (MAO), with differing efficacy on isoforms: greater inhibitionFormula:C13H12O4Purity:98%Color and Shape:SolidMolecular weight:232.23COX-2-IN-33
COX-2-IN-33 (compound 5f) is a selective COX-2 inhibitor with an IC50 value of 45.5 nM and exhibits potential as an anti-inflammatory agent.Formula:C20H13ClF3N5O4Purity:98%Color and Shape:SolidMolecular weight:479.85-HT6R antagonist 1
Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stabilityFormula:C17H22F2N6OPurity:98%Color and Shape:SolidMolecular weight:364.39(S)-UFR2709 hydrochloride
CAS:(S)-UFR2709 HCl: competitive nAChR blocker, prefers α4β2 over α7, lessens anxiety & alcohol intake in rats, studies nicotine addiction.Formula:C13H18ClNO2Purity:98.94%Color and Shape:SolidMolecular weight:255.74RS 56812
CAS:RS 56812 is a 5-HT3 receptor antagonist and agonist used in the study of cognitive disorders.Formula:C18H21N3O2Purity:99.38%Color and Shape:SoildMolecular weight:311.38Brexpiprazole S-oxide D8
CAS:Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.Formula:C25H19D8N3O3SPurity:98%Color and Shape:SolidMolecular weight:457.61CC-3240
CAS:CC-3240 (compound 13), a molecular glue degrader of CaMKK2 based on CC-8977, has an IC50 of 9 nM [1].Formula:C52H64N6O7SMolecular weight:917.17Cloxacepride
CAS:cloxacepride is a CaM antagonist that is used to treat asthma disease.Formula:C22H27Cl2N3O4Purity:99.76%Color and Shape:SolidMolecular weight:468.37SIB 1553A
CAS:SIB 1553A is an agonist of nAChRs, a cognitive enhancer that can be used to study diseases associated with neurodegeneration.Formula:C13H19NOSPurity:99.79%Color and Shape:SoildMolecular weight:237.36(±)-LY367385
CAS:(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.Formula:C10H11NO4Color and Shape:SolidMolecular weight:209.201GSK-3β inhibitor 27
GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.Formula:C16H17ClN4O2Color and Shape:SolidMolecular weight:332.795-MeO-pyr-T
CAS:5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.Formula:C15H20N2OColor and Shape:SolidMolecular weight:244.33ALEPH hydrochloride
CAS:ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.Formula:C12H20ClNO2SColor and Shape:SolidMolecular weight:277.81ECPLA
CAS:ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.Formula:C21H25N3OColor and Shape:SolidMolecular weight:335.44Ethylpropyltryptamine
CAS:Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.Formula:C15H22N2Color and Shape:SolidMolecular weight:230.354-Hydroxy MET
CAS:4-Hydroxy MET (4-HO-MET) is a tryptamine-based new psychoactive substance (NPS), structurally similar to the endogenous neurotransmitter serotonin. It has hallucinogenic properties that affect mood, movement, and cognitive functions.Formula:C13H18N2OColor and Shape:SolidMolecular weight:218.34-Chloromethamphetamine hydrochloride
CAS:4-Chloromethamphetamine hydrochloride is a novel psychoactive substance belonging to the amphetamine class.Formula:C10H15Cl2NColor and Shape:SolidMolecular weight:220.144-fluoro MBZP
CAS:4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.Formula:C12H17FN2Color and Shape:SolidMolecular weight:208.285-HT2C agonist-4
CAS:Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.Formula:C24H25N5OColor and Shape:SolidMolecular weight:399.49DOAM
CAS:DOAM is an antagonist of the 5-HT2 receptor.Formula:C16H27NO2Color and Shape:SolidMolecular weight:265.394-Methoxyphenyl isothiocyanate
CAS:4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) is recognized as an antioxidant demonstrating an IC50 of 1.25 mM for scavenging DPPH free radicals. Its antioxidant capacity, as shown by the ORAC test, is 11.7 mM TE, equivalent to the efficacy of 11.7 mmol Trolox under similar conditions. Additionally, it extends the oxidation process in the Briggs–Rauscher reaction by approximately 9180 seconds. The compound also exhibits moderate cholinesterase inhibitory activity, with an inhibition rate of 30.4% for acetylcholinesterase (AChE) and 17.9% for butyrylcholinesterase (BChE). Research suggests 4-Methoxyphenyl isothiocyanate holds promise for applications in antioxidant and neurological disorder studies.Formula:C8H7NOSColor and Shape:SolidMolecular weight:165.21(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS:(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.Formula:C6H11NO2Color and Shape:SolidMolecular weight:129.16Triazolomethylindole-3-acetic acid
CAS:Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.Formula:C13H12N4O2Color and Shape:SolidMolecular weight:256.262-Methyl-N,N-dimethyltryptamine
CAS:2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.Formula:C13H18N2Color and Shape:SolidMolecular weight:202.3Cannabidiolic acid methyl ester
CAS:Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.Formula:C23H32O4Color and Shape:SolidMolecular weight:372.55-HT2A receptor agonist-5
CAS:5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.Formula:C23H29N3OColor and Shape:SolidMolecular weight:363.5Paynantheine
CAS:Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.Formula:C23H28N2O4Color and Shape:SolidMolecular weight:396.48Nitrazolam
CAS:Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.Formula:C17H13N5O2Color and Shape:SolidMolecular weight:319.32Camlipixant
CAS:Camlipixant (BLU-5937) is an orally active purine P2X3 receptor antagonist that is potent, selective and competitive.
Formula:C23H24F2N4O4Purity:99.37%Color and Shape:SoildMolecular weight:458.46Org 13011
CAS:Org 13011 has CNS activity and induces conditioned taste aversion by mediating 5-HT 1A receptors.Formula:C18H25F3N4OPurity:98.02%Color and Shape:SoildMolecular weight:370.41Ref: TM-T28258L
1mg109.00€5mg261.00€10mg374.00€25mg583.00€50mg803.00€100mg1,063.00€200mg1,431.00€1mL*10mM (DMSO)266.00€Binospirone
CAS:Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of movement disorders associated with neurologic dysfunction.Formula:C20H26N2O4Purity:97.57% - 98.96%Color and Shape:SoildMolecular weight:358.43Ref: TM-T71138L
1mg109.00€5mg261.00€10mg374.00€25mg583.00€50mg803.00€100mg1,063.00€200mg1,459.00€1mL*10mM (DMSO)33.00€1H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester
CAS:Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。
Formula:C26H34N2O7Purity:99.44%Color and Shape:SoildMolecular weight:486.56(S)-3,4-DCPG
CAS:(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).Formula:C10H9NO6Purity:98%Color and Shape:SolidMolecular weight:239.18AC1-IN-1
CAS:AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).
Formula:C18H18FN5O2Purity:99.89%Color and Shape:SolidMolecular weight:355.37TAT-CN21 (scrambled)
TAT-CN21(scrambled) is a control peptide lacking specific targeting activity and serves as a negative control for TatCN21. TatCN21 is an effective and selective inhibitory peptide for calcium/calmodulin-dependent protein kinase II (CaMKII).Color and Shape:Odour Solid8-Aminoadenine
CAS:8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.Formula:C5H6N6Purity:99.82%Color and Shape:SolidMolecular weight:150.14Cevimeline hydrochloride hemihydrate
CAS:Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.
Formula:C20H38Cl2N2O3S2Purity:97.00%Color and Shape:SolidMolecular weight:489.55MIDD0301
CAS:MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.Formula:C19H13BrFN3O2Purity:98%Color and Shape:SolidMolecular weight:414.23C18 L-erythro Ceramide (d18:1/18:0)
CAS:C18 L-erythro Ceramide, a natural stereoisomer, inhibits rat brain mt-CDase with IC50 of 8.8 μM.Formula:C36H71NO3Color and Shape:SolidMolecular weight:565.95Soclenicant
CAS:Soclenicant is a negative-altering modulator of α 7 -nAChR for anxiety, depression, and PTSD, due to its high selectivity, oral availabilityFormula:C24H26N4O3Purity:99.57%Color and Shape:SoildMolecular weight:418.49JNJ-67569762
CAS:JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket ( IC 50 = 2.7 nM).Formula:C22H22F4N4O5SColor and Shape:SolidMolecular weight:530.49bPiDDB
CAS:bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.
Formula:C24H38Br2N2Purity:98.72%Color and Shape:SolidMolecular weight:514.38Zalospirone
CAS:Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.Formula:C24H29N5O2Purity:98.24% - 99.82%Color and Shape:SolidMolecular weight:419.52Furosemide sodium
CAS:Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.Formula:C12H10ClN2NaO5SPurity:99.52% - >99.99%Color and Shape:SolidMolecular weight:352.73SB-408124
CAS:SB408124: Non-peptide, OX1 receptor antagonist, Ki 57 nM (whole cell) and 27 nM (membrane), 50x more selective than OX2.Formula:C19H18F2N4OPurity:99.81%Color and Shape:SolidMolecular weight:356.37
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