Neuroscience
Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.
Subcategories of "Neuroscience"
- 5-HT Receptor(1,025 products)
- ACK(1 products)
- AChR(638 products)
- ATP Citrate Lyase(17 products)
- Adrenergic Receptor(3,031 products)
- BACE(37 products)
- Beta Amyloid(222 products)
- CaMK(73 products)
- Cyclooxygenase (COX) Inhibitors(600 products)
- Dopamine Receptor(445 products)
- GABA Receptor(369 products)
- Gamma-secretase(57 products)
- GluR(265 products)
- GlyT(26 products)
- Histamine Receptor(385 products)
- LRRK2(42 products)
- Melatonin Receptor(26 products)
- NMDAR(10 products)
- OX Receptor(41 products)
- Opioid Receptor(325 products)
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Found 5464 products of "Neuroscience"
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COR659
CAS:COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.Formula:C16H16ClNO3SPurity:99.75%Color and Shape:SolidMolecular weight:337.82Ref: TM-T36520
1mg38.00€5mg86.00€10mg123.00€25mg215.00€50mg299.00€100mg411.00€200mg560.00€1mL*10mM (DMSO)94.00€DQP-26
CAS:DQP-26, a potent negative allosteric modulator of NMDA receptors (NMDARs), exhibits IC50 values of 0.77 μM for GluN2C and 0.44 μM for GluN2D subunits,Formula:C28H21Cl2N3O4Purity:98%Color and Shape:SolidMolecular weight:534.39AMPA receptor modulator-5
CAS:AMPA Receptor Modulator-5 (Example 217) serves as an AMPA receptor modulator, utilized in neurological disease research [1].Formula:C20H12F4N6Purity:98%Color and Shape:SolidMolecular weight:412.34SB 258719
CAS:SB 258719 is a selective antagonist of 5-HT7 receptor with pKi of 7.5.Formula:C18H30N2O2SPurity:99.73%Color and Shape:SolidMolecular weight:338.51Ref: TM-T12855
2mg34.00€5mg52.00€10mg85.00€25mg155.00€50mg240.00€100mg355.00€200mg502.00€1mL*10mM (DMSO)58.00€Tiotropium Bromide hydrate
CAS:Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.Formula:C19H24BrNO5S2Purity:98.44% - 99.41%Color and Shape:SolidMolecular weight:490.43MDL-74156
CAS:MDL-74156 is an active metabolite of dolasetron and a 5-hydroxy-tryptamine3 (5-HT3) antagonist.Formula:C19H22N2O3Color and Shape:SolidMolecular weight:326.39Wf-516
CAS:Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressantFormula:C25H25Cl2N3O4Purity:98%Color and Shape:SolidMolecular weight:502.39(-)-Bicuculline methochloride
CAS:(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.
Formula:C21H20ClNO6Purity:98%Color and Shape:SolidMolecular weight:417.84AAK1-IN-2
CAS:AAK1-IN-2, a potent (IC50=5.8 nM) AAK1 inhibitor, selective & brain-penetrant, is used for neuropathic pain studies.Formula:C20H20N4Color and Shape:SolidMolecular weight:316.4Antioxidant agent-15
CAS:Antioxidant agent-15 (Compound 4) demonstrates potent antioxidant inhibition activity, exhibiting an IC50 value of 15.44 nM.Formula:C19H14O2Purity:98%Color and Shape:SolidMolecular weight:274.31MAO-B-IN-27
CAS:MAO-B-IN-27 (Compound 12c), a monoamine oxidase B (MAO-B) inhibitor, exhibits a potent and selective inhibitory effect on hMAO-B, with an IC50 value of 8.9 nM,Formula:C16H17ClF3NOPurity:98%Color and Shape:SolidMolecular weight:331.76Quinolactacin A1
CAS:Quinolactacin A1, a strong AChE inhibitor from Penicillium citrinum, aids Alzheimer's research.Formula:C16H18N2O2Color and Shape:SolidMolecular weight:270.33Zamifenacin fumarate
CAS:Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.Formula:C31H33NO7Purity:99.88%Color and Shape:SolidMolecular weight:531.6Ref: TM-T13385
2mg34.00€5mg50.00€10mg75.00€25mg128.00€50mg200.00€100mg304.00€200mg424.00€1mL*10mM (DMSO)58.00€5-HT3-In-1
CAS:5-HT3-In-1 (compound example 8) exhabits with 5-HT3 inhibition activity.Formula:C16H21ClN4O3Purity:98%Color and Shape:SolidMolecular weight:352.822-Methyl-5-HT
CAS:2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.Formula:C11H14N2OPurity:97.18%Color and Shape:SolidMolecular weight:190.24Ref: TM-T10075
5mg50.00€10mg88.00€25mg187.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)52.00€L 687306
CAS:L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.Formula:C11H15N3OColor and Shape:SolidMolecular weight:205.26LY2033298
CAS:LY2033298 enhances oximoline's effect on hamster circadian rhythms, aiding neurosystem disorders.Formula:C13H14ClN3O2SPurity:98.78%Color and Shape:SolidMolecular weight:311.79Des-4-fluorobenzyl Mosapride
CAS:Des-4-fluorobenzyl Mosapride, the main metabolite of mosapride, acts as a gastroprokinetic agent improving upper gastrointestinal (GI) motility by stimulating the serotonin receptor 4 (5-HT4; EC50= 74.2 nM, in guinea pig ileal longitudinal muscle myenteric plexus). It has been shown to increase colonic motility in dogs, horses, and guinea pigs in vivo. Mosapride, including this metabolite, is utilized in human and veterinary medicine to mitigate post-surgical and Parkinson's-induced constipation.Formula:C14H20ClN3O3Color and Shape:SolidMolecular weight:313.78Brilaroxazine
CAS:Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.Formula:C22H25Cl2N3O3Purity:99.36%Color and Shape:SolidMolecular weight:450.36Ref: TM-T14782
1mg105.00€5mg250.00€10mg406.00€25mg700.00€50mg1,008.00€100mg1,378.00€200mg1,833.00€1mL*10mM (DMSO)283.00€4-Chloro-L-phenylalanine
CAS:4-Chloro-L-phenalanine (L-PCPA) is an inhibitor of 5-HT biosynthesis and a non-specific antagonist of tryptophan hydroxylases (TPH1 and TPH2).Formula:C9H10ClNO2Purity:99.76% - 99.96%Color and Shape:SolidMolecular weight:199.63BMS-983970
CAS:BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.Formula:C26H26F4N4O3Color and Shape:SolidMolecular weight:518.5AAK1-IN-5
CAS:AAK1-IN-5: Potent, selective AAK1 inhibitor; CNS-penetrant; oral; IC50: 1.2 nM; Ki: 0.05 nM; cell IC50: 0.5 nM. Useful in neuropathic pain research.Formula:C19H23F4N3OColor and Shape:SolidMolecular weight:385.4Timepidium bromide
CAS:Timepidium bromide is an agent of anticholinergic.Formula:C17H22BrNOS2Purity:98%Color and Shape:SolidMolecular weight:400.4Osemozotan Free Base
CAS:Osemozotan Free Base is a 5-HT(1A) receptor agonist.Formula:C19H21NO5Color and Shape:SolidMolecular weight:343.37MAO-IN-3
CAS:MAO-IN-3 (Compound 5), a reversible and competitive monoamine oxidase (MAO) inhibitor with inhibition constants (K i) of 0.6 μM for MAO A and 0.2 μM for MAO B,Formula:C42H54N4O4Purity:98%Color and Shape:SolidMolecular weight:678.9YM348
CAS:YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).Formula:C14H17N3OPurity:98%Color and Shape:SolidMolecular weight:243.3Lanabecestat camsylate
CAS:Lanabecestat camsylate is used as a BACE1 Inhibitor.Formula:C36H44N4O5SPurity:98%Color and Shape:SolidMolecular weight:644.83AAK1-IN-3
CAS:AAK1-IN-3: Brain-penetrant AAK1 inhibitor for neuropathic pain research; IC50=11 nM.Formula:C20H20N4Color and Shape:SolidMolecular weight:316.4GMA-839
CAS:GMA-839 is a selective modulator of gamma-aminobutyric acid(A) receptors.Formula:C21H31F3O3Purity:98%Color and Shape:SolidMolecular weight:388.46(±)-Fabesetron hydrochloride
CAS:FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.Formula:C18H20ClN3OPurity:98%Color and Shape:SolidMolecular weight:329.82FK-1052
CAS:FK-1052 is a serotonin 3 & 4 dual receptor antagonist.Formula:C18H19N3OColor and Shape:SolidMolecular weight:293.36MK-8768
CAS:MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized byFormula:C21H22F3N5O2Color and Shape:SolidMolecular weight:433.43Piperidine-4-sulfonic acid
CAS:Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].Formula:C5H11NO3SPurity:98%Color and Shape:SolidMolecular weight:165.21PNU109291
CAS:PNU109291, a potent and selective agonist of the 5-HT1D receptor, effectively mitigates dural plasma extravasation induced by trigeminal ganglion stimulation.Formula:C24H31N3O3Purity:98%Color and Shape:SolidMolecular weight:409.52AAK1-IN-4
CAS:AAK1-IN-4 selectively inhibits AAK1 with IC50 of 4.6 nM; penetrates CNS, oral bioactive, potential for studying neuropathic pain.Formula:C20H28N4O3Color and Shape:SolidMolecular weight:372.46mGAT3/4-IN-2
CAS:mGAT3/4-IN-2 are potent inhibitors of mGAT3/mGAT4 with their pIC50 values of 5.44 and 5.25, respectively.Formula:C26H32ClN3OS2Color and Shape:SolidMolecular weight:502.13CGP 64213
CAS:CGP 64213 is a GABAb receptor agonist.Formula:C26H36IN2O7PPurity:98%Color and Shape:SolidMolecular weight:646.45CGP 54626 hydrochloride
CAS:CGP 54626 hydrochloride is a GABAB receptor antagonist.Formula:C18H29Cl3NO3PPurity:98%Color and Shape:SolidMolecular weight:444.76CGP 55845
CAS:CGP 55845: potent, selective GABAB blocker, IC50=5 nM, hinders agonist binding, reduces GABA/glutamate release.Formula:C18H22Cl2NO3PColor and Shape:SolidMolecular weight:402.25mGAT-IN-1
CAS:mGAT-IN-1 is a potent, non-selective GAT inhibitor that inhibits mGAT3 activity well (IC50: 2.5 μM, pIC50: 5.61).Formula:C28H34ClN3O2S2Color and Shape:SolidMolecular weight:544.17Afizagabar
CAS:Afizagabar, a first-in-class α5-GABAAR antagonist, IC50: 585 nM, Ki: 66 nM, may boost memory.Formula:C19H12FN3O2SColor and Shape:SolidMolecular weight:365.38AChE-IN-44
CAS:AChE-IN-44 (Compound Tap4), an AChE inhibitor, is convertible into its thiazole salt form known as Tat2 [1].Formula:C31H38ClN3OS2Color and Shape:SolidMolecular weight:568.24MTPG
CAS:Group II/group III metabotropic glutamate receptor antagonistFormula:C10H11N5O2Purity:98%Color and Shape:SolidMolecular weight:233.23LY320954
CAS:LY320954 is an antagonist of 5-HT2A receptor.Formula:C21H26N4O3Purity:98%Color and Shape:SolidMolecular weight:382.46ASS234
CAS:ASS234 is a multi-target propylamine used in the treatment of Alzheimer's disease.Formula:C29H37N3OColor and Shape:SolidMolecular weight:443.62(1α,1'S,4β)-Lanabecestat
CAS:(1α,1'S,4β)-Lanabecestat is a Beta site APP Cleaving Enzymel (BACE1) inhibitor, and has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay),Formula:C26H28N4OColor and Shape:SolidMolecular weight:412.53RAGE/SERT-IN-1
CAS:RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM andFormula:C38H41ClN4OSColor and Shape:SolidMolecular weight:637.28SDZ-216525
CAS:SDZ-216525, a 5-HT1A receptor antagonist, inhibits the tracheal contractions induced both by NKA (10 nM-3 microM) and 5-HT (10 nM-10 microM) (n=4-10).Formula:C25H28N4O5SColor and Shape:SolidMolecular weight:496.583-Bromocytisine
CAS:3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).Formula:C11H13BrN2OPurity:99.974%Color and Shape:SolidMolecular weight:269.14Ref: TM-T10108
1mg95.00€5mg202.00€10mg293.00€25mg494.00€50mg710.00€100mg973.00€200mg1,305.00€1mL*10mM (DMSO)178.00€(R)-4-Amino-3-hydroxybutyric Acid
CAS:(R)-4-Amino-3-hydroxybutyric acid, also known as (R)-GABOB, acts as a modulator of GABA receptors, specifically binding to both GABAA and GABAB receptors and blocking GABA reuptake in rat brain synaptosomes. Additionally, it serves as a GABAC receptor agonist, triggering currents in patch-clamp assays with Xenopus oocytes that express the human receptor. In vivo studies reveal its capability to suppress electrical discharges in the amygdala in cats undergoing N-amidinobenzamide-triggered seizures, indicating its potential therapeutic application in managing seizure disorders.Formula:C4H9NO3Color and Shape:SolidMolecular weight:119.12
