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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5400 products of "Neuroscience"

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  • CaMKIIα-IN-1


    <p>CaMKIIα-IN-1 (Compound 4d) is an orally active inhibitor of Ca 2+ /calmodulin-dependent protein kinase II α (CaMKIIα) with a Kd of 219 nM for CaMKIIα WT hub.</p>
    Formula:C14H11ClO4
    Color and Shape:Solid
    Molecular weight:278.69
  • Anti-Aβ agent 1A


    <p>Anti-Aβ agent 1A is a potent anti-amyloid-β agent.</p>
    Formula:C35H49NO4
    Color and Shape:Solid
    Molecular weight:547.77
  • eeAChE-IN-1


    <p>eeAChE-IN-1 is a strong inhibitor of eeAChE (IC50: 23 nM).</p>
    Formula:C27H30N6O5S
    Color and Shape:Solid
    Molecular weight:550.63
  • BACE1-IN-2

    CAS:
    <p>BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).</p>
    Formula:C19H15F4N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:421.35
  • LOXL2-IN-1 tosylate


    <p>LOX-IN-5 tosylate (compound 22) is a selective oral inhibitor of lysyl oxidase-like 2 (LOXL2) with an IC50 of less than 300 nM, and it exhibits anti-fibrotic properties.</p>
    Formula:C28H33FN4O5S2
    Color and Shape:Solid
    Molecular weight:588.714
  • PTCA

    CAS:
    <p>PTCA is a potent ligand for Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα), with a pKi value of 7.2.</p>
    Formula:C10H5Cl2NO2S
    Color and Shape:Solid
    Molecular weight:274.123
  • SB 258741 hydrochloride


    <p>SB 258741 hydrochloride is a potent antagonist of the 5-HT 7 receptor, designed specifically for studying schizophrenia [1].</p>
    Formula:C19H31ClN2O2S
    Color and Shape:Solid
    Molecular weight:386.98
  • γ-secretase modulator 5


    <p>Compound 22d is a GSM that crosses the blood-brain barrier, inhibits Aβ42 production (IC50: 60 nM), and may help study Alzheimer's.</p>
    Color and Shape:Solid
  • TDI-11861

    CAS:
    <p>TDI-11861 is a second-gen sAC (ADCY10) inhibitor with an IC50 of 5.5 nM and slow dissociation.</p>
    Formula:C22H25ClF2N6O3
    Color and Shape:Solid
    Molecular weight:494.92
  • LRRK2-IN-16

    CAS:
    <p>LRRK2-IN-16 (compound 25) is an inhibitor of the LRRK2 kinase with an IC50 value of less than 5 μM. It is applicable for research in neurodegenerative and autoimmune diseases.</p>
    Formula:C18H19N5OS
    Color and Shape:Solid
    Molecular weight:353.441
  • β-Secretase Inhibitor III


    <p>β-Secretase Inhibitor III is a highly selective inhibitor of BACE1 with a Ki value of 0.13 nM.</p>
    Formula:C20H20F2N4O3S
    Color and Shape:Solid
    Molecular weight:434.46
  • (-)-5-HT2C agonist-3

    CAS:
    <p>Compound (−)-19, also known as (-)-5-HT2C agonist-3, is a selective 5-HT2C agonist exhibiting a preference for Gq signaling. It demonstrates efficiency with EC50 values for 5-HT2 receptor subtypes as follows: 5-HT2C at 103 nM, 5-HT2B at 570 nM, and 5-HT2A at 72 nM. This compound is utilized in research on antipsychotics.</p>
    Formula:C19H23ClFNO2
    Color and Shape:Solid
    Molecular weight:351.84
  • DAPM

    CAS:
    <p>DAPM (gamma-Secretase Inhibitor XVI) is a Notch pathway inhibitor with anticancer activity and antiproliferative effects.</p>
    Formula:C20H20F2N2O4
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:390.38
  • AAZ-A 154

    CAS:
    <p>AAZ-A 154 is a selective, competitive, and non-hallucinogenic antagonist of the 5-HT2AR. It promotes neuronal growth in rodents and results in lasting beneficial behavioral effects.</p>
    Formula:C14H20N2O
    Color and Shape:Solid
    Molecular weight:232.32
  • LRRK2-IN-3

    CAS:
    <p>LRRK2-IN-3: potent, selective oral LRRK2 blocker, BBB-penetrant, IC50 of 0.6 nM in hPBMCs, for Parkinson's research.</p>
    Formula:C25H29ClF2N6O2
    Color and Shape:Solid
    Molecular weight:518.99
  • LY2794193

    CAS:
    <p>LY2794193, a potent and selective mGlu3 receptor agonist, reduces akathisia seizures and increases GAT1, GLAST and GLT-1 protein levels in rats.</p>
    Formula:C16H18N2O6
    Purity:98.15%
    Color and Shape:Solid
    Molecular weight:334.32
  • AChE-IN-79


    <p>AChE-IN-79 (compound 3i) is an acetylcholinesterase inhibitor with an IC50 of 2.7 µM, suitable for studies related to Alzheimer's disease.</p>
    Formula:C29H27NO6S
    Color and Shape:Solid
    Molecular weight:517.59
  • LRRK2-IN-5


    <p>LRRK2-IN-5 is an oral, BBB-penetrating selective inhibitor for LRRK2 with IC50s: 1.2μM (GS) and 16μM (WT); halts LRRK2 autophosphorylation.</p>
    Formula:C24H26F2N4O2S
    Color and Shape:Solid
    Molecular weight:472.55
  • Pomaglumetad methionil

    CAS:
    <p>Pomaglumetad methionil is an oral methionine prodrug of the potent specific agonist of mGlu2/3 receptor LY404039.</p>
    Formula:C12H20N2O8S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:384.43
  • 5-HT6R/MAO-B modulator 1


    <p>5-HT6R/MAO-B modulator 1 blocks 5-HT6R and permanently inhibits MAO-B, protects glial cells, and reverses memory loss.</p>
    Formula:C33H38N4O3S
    Color and Shape:Solid
    Molecular weight:570.74