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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5390 products of "Neuroscience"

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  • 2002-G12

    CAS:
    <p>2002-G12 (compound 5a) is an Aβ42 inhibitor that can reduce Aβ42 toxicity by 76%. It is applicable in Alzheimer's research.</p>
    Formula:C20H16N6
    Color and Shape:Solid
    Molecular weight:340.381
  • β-Secretase Inhibitor III


    <p>β-Secretase Inhibitor III is a highly selective inhibitor of BACE1 with a Ki value of 0.13 nM.</p>
    Formula:C20H20F2N4O3S
    Color and Shape:Solid
    Molecular weight:434.46
  • Rocavorexant

    CAS:
    <p>Rocavorexant is an antagonist of the orexin-1 receptor (orexin-1 receptor), exhibiting a pIC50 value of 9.1 for human OX1 and a pIC50 of 6.0 for human OX2.</p>
    Formula:C18H19F3N8O
    Color and Shape:Solid
    Molecular weight:420.392
  • Serotonin maleate

    CAS:
    <p>Serotonin hydrogen maleate serves as a monoaminergic neurotransmitter and an endogenous 5-HT receptor agonist within the central nervous system (CNS). It also functions as an inhibitor of catechol O-methyltransferase (COMT), exhibiting a Ki value of 44 μM.</p>
    Formula:C14H16N2O5
    Color and Shape:Solid
    Molecular weight:292.287
  • BACE1-IN-2

    CAS:
    <p>BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).</p>
    Formula:C19H15F4N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:421.35
  • Monoamine Oxidase B inhibitor 1


    <p>Potent, selective MAO-B inhibitor; reversible; oral; crosses BBB; IC50=0.02 nM; potential for Parkinson's research.</p>
    Formula:C18H15FO3
    Color and Shape:Solid
    Molecular weight:298.31
  • PTCA

    CAS:
    <p>PTCA is a potent ligand for Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα), with a pKi value of 7.2.</p>
    Formula:C10H5Cl2NO2S
    Color and Shape:Solid
    Molecular weight:274.123
  • LRRK2-IN-6


    <p>LRRK2-IN-6 is an oral, selective LRRK2 inhibitor crossing the blood-brain barrier, targeting GS (IC50: 4.6μM) and WT LRRK2 (IC50: 49μM).</p>
    Formula:C23H24F2N4O2S
    Color and Shape:Solid
    Molecular weight:458.52
  • Terguride

    CAS:
    <p>Terguride: treats hyperprolactinemia, blocks 5-HT2A/B, activates dopamine receptors, studied for PAH.</p>
    Formula:C20H28N4O
    Color and Shape:Solid
    Molecular weight:340.46
  • Rodatristat

    CAS:
    <p>Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).</p>
    Formula:C27H27ClF3N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:561.98
  • AAK1-IN-2 TFA


    <p>AAK1-IN-2 TFA (compound (S)-31) is a selective and potent AAK1 inhibitor (IC50: 5.8 nM) that can cross the blood-brain barrier.</p>
    Formula:C24H22F6N4O4
    Color and Shape:Solid
    Molecular weight:544.45
  • ChEs/MAOs-IN-2

    CAS:
    ChEs/MAOs-IN-2 (compound a11) serves as an inhibitor for both cholinesterases and monoamine oxidases, exhibiting IC 50 values of 0.10 µM for MAO-A, 0.20 µM for MAO-B, 0.30 µM for AChE, and 0.40 µM for BChE. This compound shows promise for Alzheimer's disease research [1].
    Formula:C15H12N2O3S
    Color and Shape:Solid
    Molecular weight:300.33
  • SNRI-IN-1

    CAS:
    SNRI-IN-1 (Compound 7a) acts as a dual inhibitor of serotonin and noradrenaline monoamine reuptake, with a P-glycoprotein Efflux Ratio of 20 [1].
    Formula:C16H20Cl2N2O2
    Color and Shape:Solid
    Molecular weight:343.25
  • AChE-IN-25


    <p>AChE-IN-25: selective, potent AChE inhibitor, non-competitive, IC50 = 2.95 μM, for Alzheimer's research.</p>
    Formula:C20H15ClN4O4S
    Color and Shape:Solid
    Molecular weight:442.88
  • QP5020

    CAS:
    QP5020 is a QPCTL inhibitor with an IC50 value of 15 nM, demonstrating antitumor efficacy.
    Formula:C20H19FN6
    Molecular weight:362.40
  • SGE-516

    CAS:
    <p>SGE516: neuroactive steroid, enhances GABAA, lowers neuronal activity, protects from seizures.</p>
    Formula:C23H35N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:385.54
  • U92016A hydrochloride

    CAS:
    <p>U92016A hydrochloride: potent, orally active 5-HT1A agonist, metabolically stable, high intrinsic activity, Ki=0.2 nM.</p>
    Formula:C19H26ClN3
    Color and Shape:Solid
    Molecular weight:331.89
  • MAO-A inhibitor 1

    CAS:
    <p>MAO-A Inhibitor 1 (compound VIII) acts as a MAO-A inhibitor and exhibits an IC50 value of 100 μM [1].</p>
    Formula:C14H12O4
    Color and Shape:Solid
    Molecular weight:244.24
  • LRRK2-IN-3

    CAS:
    <p>LRRK2-IN-3: potent, selective oral LRRK2 blocker, BBB-penetrant, IC50 of 0.6 nM in hPBMCs, for Parkinson's research.</p>
    Formula:C25H29ClF2N6O2
    Color and Shape:Solid
    Molecular weight:518.99
  • CaMKIIα-IN-1


    <p>CaMKIIα-IN-1 (Compound 4d) is an orally active inhibitor of Ca 2+ /calmodulin-dependent protein kinase II α (CaMKIIα) with a Kd of 219 nM for CaMKIIα WT hub.</p>
    Formula:C14H11ClO4
    Color and Shape:Solid
    Molecular weight:278.69