AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 574 products of "AChR"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Darifenacin hydrobromide
CAS:<p>Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.</p>Formula:C28H31BrN2O2Purity:99.75% - >99.99%Color and Shape:SolidMolecular weight:505.45Dicyclomine hydrochloride
CAS:<p>Dicyclomine hydrochloride is a muscarinic antagonist used as an antispasmodic and in urinary incontinence.</p>Formula:C19H36ClNO2Purity:99.81%Color and Shape:SolidMolecular weight:345.95Orphenadrine Citrate
CAS:<p>Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.</p>Formula:C18H23NO·C6H8O7Purity:98% - 99.58%Color and Shape:White SolidMolecular weight:461.5Vecuronium bromide
CAS:<p>Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscle</p>Formula:C34H57BrN2O4Purity:99.63% - 99.92%Color and Shape:White PowderMolecular weight:637.73PF-4348235 2HCl
<p>PF-4348235 2HCl is an adrenergic agonist and muscarinic receptor antagonist, and is a bronchodilator.</p>Formula:C36H51Cl3N4O7SPurity:99.85%Color and Shape:SolidMolecular weight:790.24Lysipressin acetate(50-57-7(fb_acetate))
CAS:<p>Lysipressin acetate (50-57-7), triggers rabbit bladder contraction & activates adenylate cyclase, is an antidiuretic in pigs & marsupials.</p>Formula:C48H69N13O14S2Purity:98.08%Color and Shape:SolidMolecular weight:1116.28Gallamine triethiodide
CAS:<p>Gallamine triethiodide (Benzkurin), a synthetic inhibiting drug, is nondepolarizing.</p>Formula:C30H60I3N3O3Purity:98.90%Color and Shape:White Amorphous Powder SolidMolecular weight:891.53Ribavirin
CAS:<p>Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.</p>Formula:C8H12N4O5Purity:99.09% - 99.83%Color and Shape:Less Solid Colourless SolidMolecular weight:244.20Trospium chloride
CAS:<p>Trospium chloride treats urinary incontinence without causing liver damage.</p>Formula:C25H30ClNO3Purity:99.84% - >99.99%Color and Shape:White To Off-White PowderMolecular weight:427.964V-11-0711 HCl
<p>V-11-0711 HCl is a selective and highly effective choline kinase α (ChoKα) inhibitor that inhibits the catalytic activity of Chk.</p>Formula:C27H36ClNO3Purity:99.87%Color and Shape:SolidMolecular weight:458.03Dipivefrin hydrochloride
CAS:<p>Dipivefrin hydrochloride (Dipivefrin HCl) that is available as an ophthalmic solution is a prodrug of adrenaline, which is used to treat glaucoma.</p>Formula:C19H27NO5·HClPurity:99.22% - 99.92%Color and Shape:Less Gas With A Sweet Odor Colorless Gas With A Sweet OdorMolecular weight:387.9Bambuterol hydrochloride
CAS:<p>Bambuterol hydrochloride (KWD-2183 hydrochloride) , a long-acting beta-adrenoceptor agonist, is utilized for the treating of asthma.</p>Formula:C18H30ClN3O5Purity:99.53% - 99.61%Color and Shape:White SolidMolecular weight:403.91Zelminemab
CAS:<p>Zelminemab (AMG-301) is a human monoclonal antibody designed to target and inhibit the PACAP type I (PAC1) receptor [1].</p>Purity:98.8% (SDS-PAGE); 97% (SEC-HPLC) - 98.8% (SDS-PAGE); 97% (SEC-HPLC)Color and Shape:LiquidVU 0365114
CAS:<p>VU 0365114 is a positive allosteric modulator of mAChR M5 and increases ACh-induced calcium mobilization(EC50: 2.7 μM).</p>Formula:C22H14F3NO3Purity:99.86%Color and Shape:SolidMolecular weight:397.359-Cyclopentyladenine
CAS:<p>9-Cyclopentyladenine (NSC-19486) is an adenylate cyclase inhibitor that blocks cellular morphological differentiation and phosphorylation of specific signaling</p>Formula:C10H13N5Purity:99.98%Color and Shape:SolidMolecular weight:203.24Fesoterodine fumarate
CAS:<p>Fesoterodine fumarate (Toviaz) is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties.</p>Formula:C26H37NO3·C4H4O4Purity:99.16%Color and Shape:White SolidMolecular weight:527.65Primidone
CAS:<p>Primidone (NCI-C56360) is a potent anticonvulsant agent.</p>Formula:C12H14N2O2Purity:99.91%Color and Shape:Crystals (Ntp 1992)Molecular weight:218.25Cotinine
CAS:<p>Cotinine (NIH-10498) is an alkaloid found in tobacco and is also the predominant metabolite of nicotine.</p>Formula:C10H12N2OPurity:98% - 99.89%Color and Shape:Viscous Oil SolidMolecular weight:176.222',5'-Dideoxyadenosine
CAS:<p>2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site (IC50: 3 μM).</p>Formula:C10H13N5O2Purity:99.55%Color and Shape:White SolidMolecular weight:235.24Clidinium bromide
CAS:<p>Clidinium bromide (Ro 2-3773), a synthetic anticholinergic, treats peptic ulcers and alleviates abdominal cramps and IBS symptoms.</p>Formula:C22H26BrNO3Purity:98.89% - 99.86%Color and Shape:White Crystalline SolidMolecular weight:432.35nAChR agonist 1
CAS:<p>nAChR agonist 1 (DUN71755) is a brain-permeable and orally efficacious positive allosteric α7 nicotinic acetylcholine receptor (α7 nAChR)modulator.</p>Formula:C20H18ClNO3S2Purity:97.59%Color and Shape:SolidMolecular weight:419.94SSR 180
CAS:<p>SSR 180 is a potent and subtype-selective α7 agonist with applications in the study of Alzheimer;s disease and schizophrenia.</p>Formula:C14H17BrN2O2Purity:98.82%Color and Shape:SoildMolecular weight:325.20Ipratropium bromide monohydrate
CAS:<p>Ipratropium bromide, safer than atropine, treats bronchial disorders, rhinitis, and irregular heartbeat via inhalation.</p>Formula:C20H32BrNO4Purity:97.85%Color and Shape:SolidMolecular weight:430.38Pirenzepine dihydrochloride
CAS:<p>Pirenzepine dihydrochloride (LS519) is a selective M1 muscarinic receptor antagonist, inhibiting gastric secretion.</p>Formula:C19H21N5O2·2HClPurity:99.48% - 99.62%Color and Shape:White PowderMolecular weight:424.32Promethazine hydrochloride
CAS:<p>Promethazine HCl: First-gen antihistamine, H1 and mACh blocker, affects 5-HT2A/C, D2, α1 receptors.</p>Formula:C17H20N2S·HClPurity:99.85%Color and Shape:Crystals In Water Has A Ph Of 3 5-5 0 (Ntp 1992)Molecular weight:320.88Dequalinium chloride
CAS:<p>Dequalinium chloride: topical bacteriostat, blocks apamin-sensitive K+ channels, used for wounds, oral infections, potential antifungal, risk of skin ulcers.</p>Formula:C30H40Cl2N4Purity:99.79% - 99.9%Color and Shape:SolidMolecular weight:527.59Pyrantel pamoate
CAS:<p>Pyrantel pamoate (Pyrantel embonate) is a depolarizing neuromuscular blocking agent.</p>Formula:C34H30N2O6SPurity:99.71%Molecular weight:594.69Pyrantel tartrate
CAS:<p>Pyrantel tartrate (Banminth) is broad spectrum anthelmintic for livestock.</p>Formula:C15H20N2O6SPurity:99.96%Color and Shape:White CrystalsMolecular weight:356.39Rivastigmine tartrate
CAS:<p>Rivastigmine (SDZ-ENA 713), a CNS-selective carbamate, treats dementia in Alzheimer's and Parkinson's.</p>Formula:C14H22N2O2·C4H6O6Purity:98% - 99.66%Color and Shape:White To Off-White PowderMolecular weight:400.43Temephos
CAS:<p>Temephos is an organothiophosphate insecticide and cholinesterase inhibitor for treating water with disease-carrying insects.</p>Formula:C16H20O6P2S3Purity:≥95%Color and Shape:White Crystalline Solid Or LiquidMolecular weight:466.47Adiphenine hydrochloride
CAS:<p>Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.</p>Formula:C20H25NO2·HClPurity:97.76% - 99.53%Color and Shape:White Or Almost White PowderMolecular weight:347.88Neostigmine methyl sulfate
CAS:<p>Neostigmine methyl sulfate (Syntostigmin) is a reversible inhibitor of acetylcholinesterase used in the treatment of myasthenia gravis.</p>Formula:C13H22N2O6SPurity:99.34% - 99.53%Color and Shape:Crystalline SolidMolecular weight:334.39Pancuronium dibromide
CAS:<p>Pancuronium dibromide (Pavulon), a competitive AChR antagonist, acts as a skeletal muscle relaxant. Pancuronium dibromide blocks neuromuscular transmission.</p>Formula:C35H60Br2N2O4Purity:99.86%Color and Shape:solidMolecular weight:732.67Nefiracetam
CAS:<p>Nefiracetam (DM9384), in Phase 2 trials, enhances GABA, choline, monoamine systems, and treats Ro 5-4864 convulsions.</p>Formula:C14H18N2O2Purity:97.37%Color and Shape:White To Off-White Crystalline PowderMolecular weight:246.3Carbetapentane citrate
CAS:<p>Carbetapentane citrate (Pentoxyverine citrate) , an antitussive (cough suppressant), is frequently used for a cough related to illnesses like the common cold.</p>Formula:C20H31NO3·C6H8O7Purity:99.46%Color and Shape:White To Off-White SolidMolecular weight:525.59Valethamate bromide
CAS:<p>Valethamate bromide (Resitan) is an anticholinergic agent that has antispasmodic effects and inhibits glandular secretion.</p>Formula:C19H32BrNO2Purity:>99.99%Color and Shape:SolidMolecular weight:386.37Methscopolamine
CAS:<p>Methscopolamine (Hyoscine methyl bromide) (Pamine), as a natural plant alkaloid, is a muscarinic acetylcholine receptor blocker.</p>Formula:C18H24BrNO4Purity:99.12% - ≥98%Color and Shape:SolidMolecular weight:398.29Tiotropium bromide
CAS:<p>Tiotropium bromide (BA679 BR) is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD).</p>Formula:C19H22BrNO4S2Purity:96.82% - 99.97%Color and Shape:White SolidMolecular weight:472.42Benztropine mesylate
CAS:<p>Benztropine mesylate (Benztropine methanesulfonate) is a centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON</p>Formula:C21H25NO·CH4SO3Purity:98.41% - 99.96%Color and Shape:White Crystalline Powder; Odourless Or Almost OdourlessMolecular weight:403.53Nicardipine hydrochloride
CAS:<p>Nicardipine hydrochloride is a potent calcium channel blocker used to dilate cerebral and coronary vessels.</p>Formula:C26H30ClN3O6Purity:99.58% - 99.89%Color and Shape:Yellow SolidMolecular weight:515.99Fipexide
CAS:<p>Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983.</p>Formula:C20H21ClN2O4Purity:97.6% - 99.95%Color and Shape:SolidMolecular weight:388.84Hexamethonium Bromide
CAS:<p>Hexamethonium Bromide blocks neural nicotinic AChR, poorly absorbed in the gut, doesn't pass the blood-brain barrier.</p>Formula:C12H30Br2N2Purity:99.76%Color and Shape:White Crystalline Powder And AgglomeratesMolecular weight:362.19Oxybutynin
CAS:<p>Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome.</p>Formula:C22H31NO3Purity:97.81% - 99.57%Color and Shape:White To Off-White Crystalline PowderMolecular weight:357.49Propantheline bromide
CAS:<p>Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle</p>Formula:C23H30BrNO3Purity:98% - ≥98%Molecular weight:448.4Homatropine Methylbromide
CAS:<p>Homatropine Methylbromide is the methyl bromide salt of homatropine, a synthetic tertiary amine alkaloid with antimuscarinic properties.</p>Formula:C17H24BrNO3Purity:98.97%Color and Shape:SolidMolecular weight:370.29Tazomeline
CAS:<p>Tazomeline is a muscarinic M1 receptor agonist with neuroprotective activity.</p>Formula:C14H23N3S2Purity:99.63%Color and Shape:SolidMolecular weight:297.48Tolterodine tartrate
CAS:<p>Tolterodine tartrate (PNU-200583E) is a potent antagonist for muscarinic receptor. It show selectivity for the urinary bladder and salivary glands in vivo.</p>Formula:C22H31NO·C4H6O6Purity:99.95%Color and Shape:White-To-Off-White Crystalline PowderMolecular weight:475.58Methacholine Chloride
CAS:<p>Methacholine Chloride (Acetyl-β-methylcholine chloride) is a quaternary ammonium parasympathomimetic agent with the muscarinic actions of acetylcholine.</p>Formula:C8H18ClNO2Purity:99.37% - 99.74%Color and Shape:White Hygroscopic Crystals With Slight Odor Of Dead FishMolecular weight:195.69Flavoxate hydrochloride
CAS:<p>Flavoxate hydrochloride (DW61) , a muscarinic AChR antagonist, is used in the therapy of various urinary syndromes and as an antispasmodic.</p>Formula:C24H26ClNO4Purity:99.78%Color and Shape:White SolidMolecular weight:427.92MK-7622
CAS:<p>MK-7622 (M1 receptor modulator) is a modulator of muscarinic M1 receptor positive allosteric.</p>Formula:C25H25N3O2Purity:99.77% - 99.8%Color and Shape:SolidMolecular weight:399.48Diphenmanil methylsulfate
CAS:<p>Diphenmanil methylsulfate (Diphemanil mesylate), a quaternary ammonium anticholinergic, binds muscarinic acetylcholine receptors.</p>Formula:C20H24N·CH3O4SPurity:98% - 99.27%Color and Shape:SolidMolecular weight:389.51Benactyzine hydrochloride
CAS:<p>Benactyzine hydrochloride (Neuroleptone) is a centrally acting muscarinic antagonist.</p>Formula:C20H26ClNO3Purity:99.03% - 99.94%Color and Shape:SolidMolecular weight:363.88Solifenacin succinate
CAS:<p>Solifenacin succinate (YM905) is a quinuclidine and tetrahydroisoquinoline derivative and selective M3 muscarinic antagonist, which is used as a urologic agent.</p>Formula:C23H26N2O2·C4H6O4Purity:99.85% - 99.98%Color and Shape:SolidMolecular weight:480.56Deschloroclozapine
CAS:<p>Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist.</p>Formula:C18H20N4Purity:99.61% - 99.98%Color and Shape:SolidMolecular weight:292.38Bethanechol chloride
CAS:<p>Bethanechol chloride: muscarinic agonist, boosts smooth muscle tone, used post-abdominal surgery & for urinary retention; may cause hypotension & bronchospasm.</p>Formula:C7H17N2O2·ClPurity:95% - 99.73%Color and Shape:White CrystallineMolecular weight:196.68DL-trihexyphenidyl hydrochloride
CAS:<p>DL-trihexyphenidyl hydrochloride (Trihexyphenidyl HCl) is a muscarinic antagonist.</p>Formula:C20H32ClNOPurity:99.63% - 99.71%Color and Shape:SolidMolecular weight:337.93(Rac)-ABT-202 dihydrochloride
CAS:<p>(Rac)-ABT-202 dihydrochloride is a racemate of ABT-202. ABT-202 is an nicotinic acetylcholine receptors (nAChRs) agonist and can be used as an analgesic.</p>Formula:C9H15Cl2N3Purity:97.4%Color and Shape:SolidMolecular weight:236.142Droperidol
CAS:<p>Droperidol (Dehydrobenzperidol) is a Dopamine-2 Receptor Antagonist. The mechanism of action of droperidol is as a Dopamine D2 Antagonist.</p>Formula:C22H22FN3O2Purity:97.16% - 98%Color and Shape:SolidMolecular weight:379.43Nebracetam hydrochloride
CAS:<p>Nebracetam HCl (WEB 1881 FU) is an M1-muscarinic agonist nootropic, increasing intracellular Ca2+ with an EC50 of 1.59 mM.</p>Formula:C12H17ClN2OPurity:99.23%Color and Shape:SolidMolecular weight:240.729(Rac)-Sabcomeline HCl
CAS:<p>Sabcomeline HCl is an M1 receptor agonist that can be used to study Alzheimer's disease.</p>Formula:C10H16ClN3OPurity:99.58%Color and Shape:SoildMolecular weight:229.71Atropine methyl bromide
CAS:<p>Atropine methyl bromide (Methylatropine bromide) is a quaternary ammonium salt of atropine, characterized as a muscarinic receptor (mAChR) antagonist.</p>Formula:C18H26BrNO3Purity:99.7%Color and Shape:SolidMolecular weight:384.308Carbachol
CAS:<p>Carbachol (Carbamoylcholine chloride), an analog of acetylcholine, serves as a valuable tool in the investigation of various physiological responses mediated by nicotinic (nAChR) and muscarinic (mAChR) acetylcholine receptors. These responses include smooth muscle contraction, gut motility, and neuronal signaling. Known for its agonistic properties, Carbachol activates both nAChR and mAChR, with reported Ki values ranging from 10 to 10,000 nM for different receptor types and experimental preparations.</p>Formula:C6H15ClN2O2Purity:>99.99%Color and Shape:SolidMolecular weight:182.65TAK-071
CAS:<p>TAK-071 is a potent, novel and highly selective modulator of muscarinic acetylcholine receptor 1 (M1R) positive allosteric(EC50 : 520 nM).</p>Formula:C24H24FN3O3Purity:98.02%Color and Shape:SolidMolecular weight:421.46Acetamiprid
CAS:<p>Acetamiprid: nAChR agonist, global neonicotinoid insecticide linked to neuromuscular/reproductive issues.</p>Formula:C10H11ClN4Purity:99.66%Color and Shape:White PowderMolecular weight:222.67Rocuronium bromide
CAS:<p>Rocuronium bromide (ORG 9426) is a muscle relaxant or aminosteroid non-depolarizing neuromuscular blocker, which is used to provide skeletal muscle relaxation.</p>Formula:C32H53BrN2O4Purity:99.77% - >99.99%Color and Shape:White Or Off-White PowderMolecular weight:609.68Procainamide hydrochloride
CAS:<p>Procainamide Hydrochloride (Procapan) is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog</p>Formula:C13H21N3O·HClPurity:99.83% - 99.97%Color and Shape:White To Slightly Yellow PowderMolecular weight:271.79Benzethonium chloride
CAS:<p>Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.</p>Formula:C27H42ClNO2Purity:99.91%Color and Shape:White To Off-White Solid Solid Particulate/PowderMolecular weight:448.09Methylatropine (nitrate)
CAS:<p>Methylatropine: Muscarinic antagonist, <0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.</p>Formula:C18H26N2O6Color and Shape:SolidMolecular weight:366.414β2AR/M-receptor agonist-1
CAS:<p>β2AR/M-receptor agonist-1 (example 131), a muscarinic antagonist and β2 adrenoceptor agonist (MABA), exhibits dual potency towards β2 adrenoceptor and</p>Formula:C43H56BrN3O7Color and Shape:SolidMolecular weight:806.82Perindoprilat
CAS:<p>Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.</p>Formula:C17H28N2O5Purity:99.48%Color and Shape:SolidMolecular weight:340.41DSPE-PEG1000-RVG29
<p>DSPE-PEG1000-RVG29 is a PEG compound composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 can specifically bind to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and cross the BBB.</p>Color and Shape:Odour SolidTC-2559 difumarate
CAS:<p>TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.</p>Formula:C20H26N2O9Color and Shape:SolidMolecular weight:438.43Navafenterol saccharinate
CAS:<p>AZD-8871 saccharinate is a dual-acting bronchodilator which may be useful in the treatment of Chronic Obstructive Pulmonary Disease (COPD).</p>Formula:C45H47N7O9S3Color and Shape:SolidMolecular weight:926.09Lobeline sulfate
CAS:<p>Lobeline sulfate, an alkaloid like nicotine, aids in smoking cessation, insomnia, and respiratory issues. Less potent on nicotinic receptors.</p>Formula:C22H29NO6SPurity:98%Color and Shape:White PowderMolecular weight:435.54(Rac)-5-Hydroxymethyl Tolterodine hydrochloride
CAS:<p>(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.</p>Formula:C22H32ClNO2Color and Shape:SolidMolecular weight:377.95Epiboxidine
CAS:<p>Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.</p>Formula:C10H14N2OColor and Shape:SolidMolecular weight:178.23Lupanine hydrochloride
CAS:<p>Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.</p>Formula:C15H25ClN2OColor and Shape:SolidMolecular weight:284.83MK-0969
CAS:<p>MK-0969 (J-104135) is a possible M3 antagonist for the treatment of chronic obstructive pulmonary disease.</p>Formula:C24H30F2N4O2Color and Shape:SolidMolecular weight:444.52Muscarine
CAS:<p>Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.</p>Formula:C9H20NO2Purity:98%Color and Shape:SolidMolecular weight:174.26Anagyrine hydrochloride
CAS:<p>Anagyrine hydrochloride, a quinolizidine from Lupinus albus, targets muscarinic/nicotinic receptors; IC50: 132/2096 µM. It desensitizes nAChR directly.</p>Formula:C15H21ClN2OColor and Shape:SolidMolecular weight:280.79AC1-IN-1
CAS:<p>AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).</p>Formula:C18H18FN5O2Purity:99.89%Color and Shape:SolidMolecular weight:355.37(rel)-Asperparaline A
CAS:<p>Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.</p>Formula:C20H29N3O3Color and Shape:SolidMolecular weight:359.47Perlapine
CAS:<p>Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).</p>Formula:C19H21N3Color and Shape:SolidMolecular weight:291.39TMPH
CAS:<p>TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.</p>Formula:C16H31NO2Purity:99.78%Color and Shape:SoildMolecular weight:269.428-Aminoadenine
CAS:<p>8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.</p>Formula:C5H6N6Purity:99.82%Color and Shape:SolidMolecular weight:150.14TDI-10229
CAS:<p>TDI-10229: potent oral sAC inhibitor, IC50=195 nM. Good mouse pharmacokinetics for in vivo use.</p>Formula:C16H16ClN5Purity:99.85% - 99.89%Color and Shape:SoildMolecular weight:313.78M3/PDE4 modulator-1
<p>M3/PDE4 Modulator-1 (compound 10f) serves as a bifunctional entity functioning both as an M3 mAChR antagonist and a PDE4 inhibitor.</p>Formula:C38H41Cl2N3O8SColor and Shape:SolidMolecular weight:770.72(R)-Dinotefuran
CAS:<p>(R)-Dinotefuran, a neonicotinoid, is 1.7-2.4x more effective against pests like Aphis gossypii and safer for bees.</p>Formula:C7H14N4O3Color and Shape:SolidMolecular weight:202.21nAChR modulator-1
CAS:<p>nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .</p>Formula:C12H8ClN3O2Color and Shape:SolidMolecular weight:261.66nAChR agonist CMPI hydrochloride
CAS:<p>CMPI hydrochloride: Potent α4:α4 nAChR PAM; EC50 0.26 μM for (α4)3(β2)2 response to ACh; may aid nicotine dependence, neuropsychiatric research.</p>Formula:C18H20Cl2N4OColor and Shape:SolidMolecular weight:379.29Dicloromezotiaz
CAS:<p>Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.</p>Formula:C19H12Cl3N3O2SColor and Shape:SolidMolecular weight:452.74Navafenterol
CAS:<p>AZD-8871, a potential COPD and asthma treatment, may work well with ICS.</p>Formula:C38H42N6O6S2Color and Shape:SolidMolecular weight:742.91α-Conotoxin PIA TFA
<p>α-Conotoxin PIA TFA, targeting nicotinic acetylcholine receptor (nAChR) subtypes with α6 and α3 subunits, acts as an antagonist.</p>Formula:C81H126F3N27O27S4Purity:98.81%Color and Shape:SolidMolecular weight:2095.3α-Conotoxin imi
CAS:<p>alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.</p>Formula:C52H78N20O15S4Purity:98%Color and Shape:SolidMolecular weight:1351.56α-Bungarotoxin
CAS:<p>Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs).</p>Formula:C338H529N97O105S11Purity:98%Color and Shape:SolidMolecular weight:7984.14Doxacurium Chloride
CAS:<p>Doxacurium Chloride is a muscarinic acetylcholine receptor M2 antagonist.</p>Formula:C56H78ClN2O16Purity:98%Color and Shape:SolidMolecular weight:1070.69G-Protein antagonist peptide
CAS:<p>Peptide inhibits G protein-receptor binding; competitively blocks M2 and β-adrenoceptor-induced Gs/Gi/Go activation.</p>Formula:C57H64N12O9SPurity:98%Color and Shape:SolidMolecular weight:1093.27Heliosupine N-oxide
<p>Heliosupine N-oxide is a useful organic compound for research related to life sciences and the catalog number is T125058.</p>Formula:C20H31NO8Color and Shape:SolidMolecular weight:413.467rac-Desethyl Oxybutynin (hydrochloride)
CAS:<p>rac-Desethyl oxybutynin, active oxybutynin metabolite, binds to mAChRs; K_i values 3.12-16 nM; lowers rat micturition pressure.</p>Formula:C20H28ClNO3Color and Shape:SolidMolecular weight:365.89α-Conotoxin AuIB
CAS:<p>Selective antagonist of α3β4 nicotinic acetylcholine receptors.</p>Formula:C65H89N17O21S4Purity:98%Color and Shape:SolidMolecular weight:1572.76
