
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(34 products)
- Cysteine Protease(96 products)
- DPP-4(20 products)
- Glutaminase(40 products)
- HIV Protease(447 products)
- PAI-1(25 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(94 products)
- Serine Protease(50 products)
- p97(14 products)
Show 3 more subcategories
Found 1045 products of "Proteases/Proteasome"
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CL 82198 hydrochloride
CAS:<p>CL 82198 hydrochloride selectively inhibits MMP-13, not MMP-1/9/TACE, and blocks HP75 invasion and neurotoxicity in zebrafish.</p>Formula:C17H23ClN2O3Color and Shape:SolidMolecular weight:338.83Acetyl-Calpastatin(184-210)(human)
CAS:<p>Calpain inhibitor, Ki 0.2 nM for calpain I/II, doesn't affect papain/trypsin/cat L. Raises Aβ42, Aβ40 secretion & Aβ42/Aβ40 ratio.</p>Formula:C142H230N36O44SPurity:98%Color and Shape:SolidMolecular weight:3177.65Anticancer agent 114
<p>Anticancer agent 114: oral dipeptide boronic acid, proteasome inhibitor, IC 50 = 2.2 nM, halts RPMI-8226 cell growth, for multiple myeloma research.</p>Formula:C28H33BF6N2O7Color and Shape:SolidMolecular weight:634.37AP-C2
CAS:<p>AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.</p>Formula:C18H16N4SPurity:99.87%Color and Shape:SoildMolecular weight:320.41C-telopeptide
CAS:<p>C-telopeptide from type I collagen is released during bone resorption; it correlates with bone mineral density.</p>Formula:C34H56N14O13Purity:98%Color and Shape:SolidMolecular weight:868.9Tyrosinase-IN-32
<p>Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.</p>Formula:C15H19NO3Color and Shape:SolidMolecular weight:261.32EP 171
CAS:<p>EP 171 is a potent agonist of TP-receptors.</p>Formula:C23H29FO5Color and Shape:SolidMolecular weight:404.47Elastatinal
CAS:<p>Elastatinal is an elastase inhibitor. It is found in culture filtrates of various species of actinomyces.</p>Formula:C21H36N8O7Color and Shape:Yellowish SolidMolecular weight:512.56Ac-DEMEEC-OH
CAS:<p>Ac-DEMEEC-OH is a competitive inhibitor of the HCV NS3 protease with a Ki of 0.6 µM.</p>Formula:C29H44N6O16S2Color and Shape:SolidMolecular weight:796.82HIV-1 TAT (48-60) Acetate
<p>Lilotomab (HH1) is a murine anti-CD37 antibody that can be used to synthesize anti-CD37 antibody-radionuclide couplings.</p>Formula:C72H135N35O18Purity:99.93%Color and Shape:SoildMolecular weight:1779.07STK33-IN-1
CAS:<p>STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC 50 of 7 nM.</p>Formula:C24H27N7O2Color and Shape:SolidMolecular weight:445.527GSK2818713
CAS:<p>GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.</p>Formula:C46H56N8O8Color and Shape:SolidMolecular weight:849.002FiVe1
CAS:<p>FiVe1 is a vimentin-binding compound that disrupts mitosis in cancer cells, causing cell death, with an IC50 of 234 nM in FOXC2-HMLER.</p>Formula:C18H16Cl2N4Purity:99.67%Color and Shape:SolidMolecular weight:359.25BMS-767778
CAS:<p>BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.</p>Formula:C19H20Cl2N4O2Color and Shape:SolidMolecular weight:407.29Linagliptin Methyldimer
CAS:<p>Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.</p>Formula:C50H56N16O4Purity:97.23%Color and Shape:SolidMolecular weight:945.08RXP470
CAS:<p>RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).</p>Formula:C35H35BrClN4O10PColor and Shape:SolidMolecular weight:818Plasma kallikrein-IN-1
CAS:<p>Plasma kallikrein-IN-1 is a PKK inhibitor with an IC 50 value of 0.5 nM.</p>Formula:C23H25F2N7OColor and Shape:SolidMolecular weight:453.498Paritaprevir dihydrate
CAS:<p>Paritaprevir dihydrate: potent oral HCV NS3/4A inhibitor (EC50: 0.21-1 nM), SARS-CoV-3CL blocker (IC50: 1.31 μM), metabolized by CYP3A, boosted by Ritonavir.</p>Formula:C40H47N7O9SColor and Shape:SolidMolecular weight:801.91CTTHWGFTLC, CYCLIC
CAS:<p>CTT Gelatinase Inhibitor peptide blocks MMP-2/9, hindering cancer by stopping tumor growth.</p>Formula:C52H71N13O14S2Purity:98%Color and Shape:SolidMolecular weight:1166.33midesteine
CAS:<p>Midesteine (MR-889) is a small molecule neutrophil elastase inhibitor used in the treatment of bronchitis, asthma and chronic lung disease.</p>Formula:C12H13NO3S3Purity:99.52% - 99.98%Color and Shape:SolidMolecular weight:315.43

