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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 985 products of "Proteases/Proteasome"

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  • TMC647055 Choline salt


    TMC647055 choline salt is a selective and cell-permeating inhibitor of HCV NS5B (IC50: 34 nM).
    Formula:C37H53N5O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:727.91

    Ref: TM-T13170

    25mg
    To inquire
    50mg
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    100mg
    To inquire
  • Cathepsin C-IN-6


    Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastase
    Formula:C24H35N5O4·xC2HF3O2
    Color and Shape:Solid

    Ref: TM-T79496

    5mg
    To inquire
    50mg
    To inquire
  • LXE408 fumarate


    LXE408 fumarate: orally available, selective kinetoplastid proteasome inhibitor with IC50/EC50 of 0.04 μM for L. donovani; potentially aids in VL research.

    Formula:C27H22FN7O6
    Purity:99.89%
    Color and Shape:Soild
    Molecular weight:559.51

    Ref: TM-T39214L

    1mg
    315.00€
    2mg
    472.00€
    5mg
    595.00€
    10mg
    947.00€
    25mg
    1,396.00€
    50mg
    1,890.00€
    100mg
    2,547.00€
  • L 659286

    CAS:
    L 659286 is one kind of cephalosporin derivative.
    Formula:C17H21N5O7S2
    Color and Shape:Solid
    Molecular weight:471.51

    Ref: TM-T32460

    25mg
    1,369.00€
  • Nostosin G


    Nostosin G, a linear peptide with Hpla, Hty, and argininal, inhibits trypsin effectively (IC50 = 0.1 μM).
    Formula:C25H33N5O6
    Color and Shape:Solid
    Molecular weight:499.56

    Ref: TM-T75647

    5mg
    To inquire
    50mg
    To inquire
  • Sadopeptins B


    Sadopeptins B, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].
    Formula:C48H69N9O13S
    Color and Shape:Solid
    Molecular weight:1012.18

    Ref: TM-T75624

    5mg
    To inquire
    50mg
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  • Talabostat

    CAS:
    Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.
    Formula:C9H19BN2O3
    Color and Shape:Solid
    Molecular weight:214.07

    Ref: TM-T37861

    5mg
    100.00€
    10mg
    148.00€
    50mg
    545.00€
  • Ac-Phe-Gly-pNA

    CAS:
    Ac-Phe-Gly-pNA is the chymotrypsin specific substrate [1] .
    Formula:C19H20N4O5
    Color and Shape:Solid
    Molecular weight:384.39

    Ref: TM-T74692

    5mg
    To inquire
    50mg
    To inquire
  • Aristololactam IIIa

    CAS:
    Aristololactam IIIa inhibits superoxide and elastase generation; IC50: 0.12 μg/mL and 0.20 μg/mL.
    Formula:C16H9NO4
    Color and Shape:Solid
    Molecular weight:279.25

    Ref: TM-T75619

    5mg
    To inquire
    50mg
    To inquire
  • Sadopeptins A


    Sadopeptins A, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].
    Formula:C49H71N9O13S
    Color and Shape:Solid
    Molecular weight:1026.21

    Ref: TM-T75623

    5mg
    To inquire
    50mg
    To inquire
  • RJS308


    RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)
    Formula:C63H75N13O11S
    Color and Shape:Solid
    Molecular weight:1222.42

    Ref: TM-T205591

    10mg
    To inquire
    50mg
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  • BAY 1217224

    CAS:

    BAY 1217224 is a neutral, non-prodrug Thrombin inhibitor with good oral pharmacokinetics.

    Formula:C24H27ClFN3O5
    Color and Shape:Solid
    Molecular weight:491.94

    Ref: TM-T39124

    25mg
    7,590.00€
  • Monodes(N-carboxymethyl)valine Daclatasvir

    CAS:
    Monodes(N-carboxymethyl)valine Daclatasvir, or Daclatasvir Impurity A, degrades Daclatasvir, a strong HCV NS5A inhibitor.
    Formula:C33H39N7O3
    Color and Shape:Solid
    Molecular weight:581.71

    Ref: TM-T37915

    5mg
    299.00€
    10mg
    507.00€
  • Calpain Inhibitor-1

    CAS:
    Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.
    Formula:C19H17FN6O5S
    Color and Shape:Solid
    Molecular weight:460.44

    Ref: TM-T38931

    5mg
    3,780.00€
  • Tyrosinase-IN-38


    Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.
    Color and Shape:Odour Solid

    Ref: TM-T200602

    10mg
    To inquire
    50mg
    To inquire
  • midesteine

    CAS:
    Midesteine (MR-889) is a small molecule neutrophil elastase inhibitor used in the treatment of bronchitis, asthma and chronic lung disease.
    Formula:C12H13NO3S3
    Purity:99.87% - 99.98%
    Color and Shape:Solid
    Molecular weight:315.43

    Ref: TM-T68099

    1mg
    50.00€
    5mg
    111.00€
    10mg
    165.00€
    25mg
    266.00€
    50mg
    379.00€
    100mg
    540.00€
    200mg
    757.00€
  • Anticancer agent 114


    Anticancer agent 114: oral dipeptide boronic acid, proteasome inhibitor, IC 50 = 2.2 nM, halts RPMI-8226 cell growth, for multiple myeloma research.
    Formula:C28H33BF6N2O7
    Color and Shape:Solid
    Molecular weight:634.37

    Ref: TM-T74839

    5mg
    To inquire
    50mg
    To inquire
  • Berotralstat

    CAS:
    Berotralstat (BCX7353) is an oral, low-toxicity, specific kallikrein inhibitor for hereditary angioedema research, blocking bradykinin release.
    Formula:C30H26F4N6O
    Color and Shape:Solid
    Molecular weight:562.56

    Ref: TM-T35869

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • Sofigatran

    CAS:
    Sofigatran (MCC-977) is an oral anticoagulant targeting thrombin for cardiovascular research.
    Formula:C24H44N4O4S
    Color and Shape:Solid
    Molecular weight:484.7

    Ref: TM-T39310

    5mg
    873.00€
  • TAPI1 acetate


    TAPI1 acetate (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α cytokine receptors; MMP inhibitor .
    Formula:C28H41N5O7
    Purity:98.82% - 99.94%
    Color and Shape:Solid
    Molecular weight:559.65

    Ref: TM-T6009L

    1mg
    560.00€
    5mg
    1,198.00€
    10mg
    1,611.00€
    25mg
    2,385.00€
    50mg
    3,222.00€