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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • CL 82198 hydrochloride

    CAS:
    <p>CL 82198 hydrochloride selectively inhibits MMP-13, not MMP-1/9/TACE, and blocks HP75 invasion and neurotoxicity in zebrafish.</p>
    Formula:C17H23ClN2O3
    Color and Shape:Solid
    Molecular weight:338.83
  • Acetyl-Calpastatin(184-210)(human)

    CAS:
    <p>Calpain inhibitor, Ki 0.2 nM for calpain I/II, doesn't affect papain/trypsin/cat L. Raises Aβ42, Aβ40 secretion &amp; Aβ42/Aβ40 ratio.</p>
    Formula:C142H230N36O44S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3177.65
  • Anticancer agent 114


    <p>Anticancer agent 114: oral dipeptide boronic acid, proteasome inhibitor, IC 50 = 2.2 nM, halts RPMI-8226 cell growth, for multiple myeloma research.</p>
    Formula:C28H33BF6N2O7
    Color and Shape:Solid
    Molecular weight:634.37
  • AP-C2

    CAS:
    <p>AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.</p>
    Formula:C18H16N4S
    Purity:99.87%
    Color and Shape:Soild
    Molecular weight:320.41
  • C-telopeptide

    CAS:
    <p>C-telopeptide from type I collagen is released during bone resorption; it correlates with bone mineral density.</p>
    Formula:C34H56N14O13
    Purity:98%
    Color and Shape:Solid
    Molecular weight:868.9
  • Tyrosinase-IN-32


    <p>Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.</p>
    Formula:C15H19NO3
    Color and Shape:Solid
    Molecular weight:261.32
  • EP 171

    CAS:
    <p>EP 171 is a potent agonist of TP-receptors.</p>
    Formula:C23H29FO5
    Color and Shape:Solid
    Molecular weight:404.47
  • Elastatinal

    CAS:
    <p>Elastatinal is an elastase inhibitor. It is found in culture filtrates of various species of actinomyces.</p>
    Formula:C21H36N8O7
    Color and Shape:Yellowish Solid
    Molecular weight:512.56
  • Ac-DEMEEC-OH

    CAS:
    <p>Ac-DEMEEC-OH is a competitive inhibitor of the HCV NS3 protease with a Ki of 0.6 µM.</p>
    Formula:C29H44N6O16S2
    Color and Shape:Solid
    Molecular weight:796.82
  • HIV-1 TAT (48-60) Acetate


    <p>Lilotomab (HH1) is a murine anti-CD37 antibody that can be used to synthesize anti-CD37 antibody-radionuclide couplings.</p>
    Formula:C72H135N35O18
    Purity:99.93%
    Color and Shape:Soild
    Molecular weight:1779.07
  • STK33-IN-1

    CAS:
    <p>STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC 50 of 7 nM.</p>
    Formula:C24H27N7O2
    Color and Shape:Solid
    Molecular weight:445.527
  • GSK2818713

    CAS:
    <p>GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.</p>
    Formula:C46H56N8O8
    Color and Shape:Solid
    Molecular weight:849.002
  • FiVe1

    CAS:
    <p>FiVe1 is a vimentin-binding compound that disrupts mitosis in cancer cells, causing cell death, with an IC50 of 234 nM in FOXC2-HMLER.</p>
    Formula:C18H16Cl2N4
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:359.25
  • BMS-767778

    CAS:
    <p>BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.</p>
    Formula:C19H20Cl2N4O2
    Color and Shape:Solid
    Molecular weight:407.29
  • Linagliptin Methyldimer

    CAS:
    <p>Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.</p>
    Formula:C50H56N16O4
    Purity:97.23%
    Color and Shape:Solid
    Molecular weight:945.08
  • RXP470

    CAS:
    <p>RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).</p>
    Formula:C35H35BrClN4O10P
    Color and Shape:Solid
    Molecular weight:818
  • Plasma kallikrein-IN-1

    CAS:
    <p>Plasma kallikrein-IN-1 is a PKK inhibitor with an IC 50 value of 0.5 nM.</p>
    Formula:C23H25F2N7O
    Color and Shape:Solid
    Molecular weight:453.498
  • Paritaprevir dihydrate

    CAS:
    <p>Paritaprevir dihydrate: potent oral HCV NS3/4A inhibitor (EC50: 0.21-1 nM), SARS-CoV-3CL blocker (IC50: 1.31 μM), metabolized by CYP3A, boosted by Ritonavir.</p>
    Formula:C40H47N7O9S
    Color and Shape:Solid
    Molecular weight:801.91
  • CTTHWGFTLC, CYCLIC

    CAS:
    <p>CTT Gelatinase Inhibitor peptide blocks MMP-2/9, hindering cancer by stopping tumor growth.</p>
    Formula:C52H71N13O14S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1166.33
  • midesteine

    CAS:
    <p>Midesteine (MR-889) is a small molecule neutrophil elastase inhibitor used in the treatment of bronchitis, asthma and chronic lung disease.</p>
    Formula:C12H13NO3S3
    Purity:99.52% - 99.98%
    Color and Shape:Solid
    Molecular weight:315.43