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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • Sucunamostat

    CAS:
    <p>Sucunamostat is an L-aspartic acid enteropeptidase inhibitor.</p>
    Formula:C22H22N4O8
    Color and Shape:Solid
    Molecular weight:470.438
  • Dutogliptin tartrate

    CAS:
    <p>Dutogliptin tartrate is an effective and selective oral dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.</p>
    Formula:C14H26BN3O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:391.18
  • ZG36


    <p>ZG36, a human Caseinolytic protease P (ClpP) agonist, non-selectively degrades respiratory chain complexes and reduces mitochondrial DNA, causing mitochondrial</p>
    Color and Shape:Odour Solid
  • Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)


    <p>Fluorogenic substrate for cathepsins D &amp; E; cleaves at Phe-Phe bond; not for B, H, L. Useful for assays and studies.</p>
    Color and Shape:Odour Solid
  • MMP-3 Inhibitor

    CAS:
    <p>MMP-3 Inhibitor is a peptide matrix metalloproteinase-3 (MMP-3) inhibitor with a Ki value of 95 nM.MMP-3 inhibitor has anticancer and antitumor activity.</p>
    Formula:C27H46N10O9S
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:686.78
  • HCV-IN-4

    CAS:
    <p>HCV-IN-4: Potent, oral HCV NS5A inhibitor; effective vs GT1a/b, GT2b, GT3a, Y93H, L31V; EC90s: 3 pM-0.02 nM.</p>
    Formula:C52H58FN9O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:956.07
  • Nitidanin


    <p>Nitidanin is a useful organic compound for research related to life sciences and the catalog number is T125599.</p>
    Formula:C21H24O8
    Color and Shape:Solid
    Molecular weight:404.415
  • Cys-TAT(47-57) acetate(583836-55-9 Free base)


    <p>Cys-TAT(47-57) acetate is derived from the HIV-1 transactivating protein. Cys-TAT(47-57) acetate is an arginine rich peptide that can penetrate cells.</p>
    Formula:C69H128N34O16S
    Purity:95.1100%
    Color and Shape:Solid
    Molecular weight:1722.04
  • CRA-2059 TFA


    <p>CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].</p>
    Color and Shape:Solid
  • MK-6169

    CAS:
    <p>MK-6169 is an effective Pan-Genotype Hepatitis C Virus NS5A inhibitor. It also has Optimized Activity against Common Resistance-Associated Substitutions.</p>
    Formula:C54H62FN9O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1016.2
  • DPP-4-IN-14


    <p>DPP-4-IN-14 (compound 30) is an inhibitor of DPP-4, with an IC50 value of 12.82 nM.</p>
    Formula:C33H27N7O3
    Color and Shape:Solid
    Molecular weight:569.613
  • Talabostat

    CAS:
    <p>Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.</p>
    Formula:C9H19BN2O3
    Color and Shape:Solid
    Molecular weight:214.07
  • Elastatinal

    CAS:
    <p>Elastatinal is an elastase inhibitor. It is found in culture filtrates of various species of actinomyces.</p>
    Formula:C21H36N8O7
    Color and Shape:Yellowish Solid
    Molecular weight:512.56
  • JC-10

    CAS:
    <p>JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe.</p>
    Formula:C25H29Cl2IN4
    Purity:95%
    Color and Shape:Solid
    Molecular weight:583.34
  • BMS-767778

    CAS:
    <p>BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.</p>
    Formula:C19H20Cl2N4O2
    Color and Shape:Solid
    Molecular weight:407.29
  • Sofosbuvir impurity H


    <p>Sofosbuvir impurity H, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir.</p>
    Formula:C29H33FN3O10P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:633.56
  • Fotagliptin

    CAS:
    <p>Fotagliptin is a dipeptidyl peptidase IV inhibitor.</p>
    Formula:C17H19FN6O
    Color and Shape:Solid
    Molecular weight:342.37
  • Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2

    CAS:
    <p>Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic probe for MMP-1 and MMP-9 detection, releasing fluorescent Nma upon cleavage (Ex/Em: 340/440 nm).</p>
    Formula:C49H68N14O12S
    Color and Shape:Solid
    Molecular weight:1077.22
  • Tilpisertib fosmecarbil TFA

    CAS:
    <p>Tilpisertib fosmecarbil TFA, the TFA salt form of Tilpisertib, acts as an inhibitor of serine/threonine kinases. This compound also exhibits anti-inflammatory activity.</p>
    Formula:C37H37ClF3N8O9P
    Color and Shape:Solid
    Molecular weight:861.16
  • Dansyl-Glu-Gly-Arg-Chloromethylketone

    CAS:
    <p>Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor that specifically impedes serine/threonine proteases and has been shown to inhibit activated</p>
    Formula:C26H36ClN7O7S
    Color and Shape:Solid
    Molecular weight:626.12