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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • Calpain Inhibitor-1

    CAS:
    <p>Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.</p>
    Formula:C19H17FN6O5S
    Color and Shape:Solid
    Molecular weight:460.44
  • Alisporivir

    CAS:
    <p>Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.</p>
    Formula:C63H113N11O12
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:1216.64
  • midesteine

    CAS:
    <p>Midesteine (MR-889) is a small molecule neutrophil elastase inhibitor used in the treatment of bronchitis, asthma and chronic lung disease.</p>
    Formula:C12H13NO3S3
    Purity:99.52% - 99.98%
    Color and Shape:Solid
    Molecular weight:315.43
  • PF 00356231

    CAS:
    <p>PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).</p>
    Formula:C25H20N2O3S
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:428.5
  • Nostopeptin B

    CAS:
    <p>Nostopeptin B is an inhibitor of elastase.</p>
    Formula:C46H70N8O12
    Color and Shape:Solid
    Molecular weight:927.11
  • EP 171

    CAS:
    <p>EP 171 is a potent agonist of TP-receptors.</p>
    Formula:C23H29FO5
    Color and Shape:Solid
    Molecular weight:404.47
  • PSI-353661

    CAS:
    <p>PSI-353661 (GS-558093), inhibits HCV's NS5B polymerase; EC90: 8nM (wild-type), 11nM (S282T); active in human hepatocytes.</p>
    Formula:C24H32FN6O8P
    Color and Shape:Solid
    Molecular weight:582.52
  • Cepeginterferon alfa-2b

    CAS:
    <p>Cepeginterferon alfa-2b: pegylated interferon with 20 kDa PEG for HCV, PV, ET research.</p>
    Color and Shape:Liquid
  • HIV-1 inhibitor-6 

    CAS:
    <p>HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing</p>
    Formula:C14H10N4O4S
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:330.32
  • 7-Methoxy obtusifolin

    CAS:
    <p>7-Methoxy obtusifolin (Compound 4) is a chemical compound that acts as a competitive inhibitor of the enzyme tyrosinase, displaying an inhibitory concentration</p>
    Formula:C17H14O6
    Color and Shape:Solid
    Molecular weight:314.29
  • Ellipyrone B


    <p>Ellipyrone B, a γ-pyrone-based macrocyclic polyketide with antihyperglycemic properties, demonstrates inhibitory activity against dipeptidyl peptidase-4 (IC 50</p>
    Formula:C25H38O7
    Color and Shape:Solid
    Molecular weight:450.57
  • AMG-222

    CAS:
    <p>AMG-222 (ALS-2-0426, ALS-20426) is a DPP-4 inhibitor and may be used in the treatment of type 2 diabetes.</p>
    Formula:C32H39N9O3
    Color and Shape:Solid
    Molecular weight:597.71
  • BPHA

    CAS:
    <p>BPHA is a selective oral inhibitor of MMP-2/9/14 (IC50: 12/16/17 nM), not affecting MMP-1/3/7, with anti-angiogenic and anti-tumor properties.</p>
    Formula:C21H20N2O4S
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:396.46
  • Obtusifolin-2-O-glucoside

    CAS:
    <p>Obtusifolin-2-O-glucoside (compound 7), a tyrosinase inhibitor with an IC50 value of 9.2 μM, can be isolated from cassia seed [1].</p>
    Formula:C22H22O10
    Color and Shape:Solid
    Molecular weight:446.4
  • Sulodexide

    CAS:
    <p>Sulodexide is an orally administered combination of glycosaminoglycans, consisting of low molecular weight heparin (80%) and dermatan sulfate (20%). It demonstrates antithrombotic properties by interacting with antithrombin III (AT III) and heparin cofactor II (HC II), and by inhibiting thrombin formation. Additionally, sulodexide enhances profibrinolytic activity by releasing tissue plasminogen activator (tPA). It also offers endothelial protection, possesses anti-inflammatory effects, and alleviates chronic venous disease.</p>
    Color and Shape:Solid
  • Isoleucylvaline

    CAS:
    <p>Isoleucylvaline is a dipeptide.</p>
    Formula:C11H22N2O3
    Color and Shape:Solid
    Molecular weight:230.30
  • Cajaninstilbene acid

    CAS:
    <p>Cajaninstilbene acid is a useful organic compound for research related to life sciences. The catalog number is T124035 and the CAS number is 87402-84-4.</p>
    Formula:C21H22O4
    Color and Shape:Solid
    Molecular weight:338.403
  • Tyrosinase-IN-36


    <p>Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.</p>
    Color and Shape:Odour Solid
  • BMS 180742

    CAS:
    <p>BMS 180742 is an exosite inhibitor of thrombin.</p>
    Formula:C67H93N11O22
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1404.52
  • Chymotrypsinogen

    CAS:
    <p>Chymotrypsinogen is an inactive precursor of Chymotrypsin . Chymotrypsin is a serine protease produced by the pancreas [1] [2] .</p>
    Color and Shape:Solid