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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 985 products of "Proteases/Proteasome"

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  • Sofosbuvir impurity M

    CAS:
    Sofosbuvir impurity M is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
    Formula:C22H30N3O10P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:527.467

    Ref: TM-T12968

    25mg
    2,403.00€
    50mg
    2,952.00€
    100mg
    3,690.00€
  • PROTAC CG167


    PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)
    Formula:C65H79N13O11S
    Color and Shape:Solid
    Molecular weight:1250.47

    Ref: TM-T205234

    10mg
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    50mg
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  • Pseudostellarin G

    CAS:
    Pseudostellarin G, a naturally occurring cyclo-octapeptide, exhibits inhibitory activity against tyrosinase and suppresses melanin production.
    Formula:C42H56N8O9
    Color and Shape:Solid
    Molecular weight:816.94

    Ref: TM-TP2861

    10mg
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    50mg
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  • 5-epi-Arvestonate A

    CAS:

    5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.

    Formula:C16H26O5
    Color and Shape:Solid
    Molecular weight:298.37

    Ref: TM-T75535

    5mg
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    50mg
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  • VD2173

    CAS:
    VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.
    Formula:C31H45N9O6S
    Color and Shape:Solid
    Molecular weight:671.81

    Ref: TM-T74390

    5mg
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    50mg
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  • N-CBZ-Phe-Arg-AMC TFA


    N-CBZ-Phe-Arg-AMC TFA (Z-FR-AMC TFA) is a fluorescent substrate for serine proteases. assess the activity of trypsin, plasmin, and cathepsin.
    Formula:C35H37F3N6O8
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:726.7

    Ref: TM-T76010

    1mg
    52.00€
    5mg
    109.00€
    10mg
    160.00€
    25mg
    314.00€
    50mg
    498.00€
  • NIM811

    CAS:
    NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.
    Formula:C62H111N11O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1202.635

    Ref: TM-T12226

    5mg
    To inquire
  • Sofosbuvir impurity A

    CAS:
    Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.
    Formula:C22H29FN3O9P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:529.45

    Ref: TM-T12956

    25mg
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    50mg
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    100mg
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  • Ecallantide TFA


    Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention of
    Color and Shape:Odour Solid

    Ref: TM-T82510

    5mg
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    50mg
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  • Phaeosphaone D

    CAS:
    Phaeosphaone D, a thiodiketopiperazine from Phaeosphaeria fuckelii fungus, inhibits mushroom tyrosinase (IC50 = 33.2 μM).
    Formula:C20H27N3O3S2
    Color and Shape:Solid
    Molecular weight:421.58

    Ref: TM-T75470

    5mg
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    50mg
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  • GSK2336805

    CAS:
    GSK-2336805, an HCV NS5A inhibitor, is effective against genotypes 1, 4, 5, and some of 6.
    Formula:C42H52N8O8
    Color and Shape:Solid
    Molecular weight:796.91

    Ref: TM-T27461

    25mg
    2,178.00€
    50mg
    2,862.00€
    100mg
    3,870.00€
  • TR-107

    CAS:
    TR-107 (Anticancer agent 230) is a mitochondrial protease ClpP activator that inhibits tumor growth in the MDA-MB-231 xenograft model.
    Formula:C22H19ClN4O
    Color and Shape:Soild
    Molecular weight:390.87

    Ref: TM-T85310

    5mg
    49.00€
    10mg
    72.00€
    25mg
    130.00€
    50mg
    203.00€
    100mg
    320.00€
    500mg
    755.00€
  • Lysine 4-nitroanilide

    CAS:
    Lysine 4-nitroanilide is a bioactive chemical.
    Formula:C12H18N4O3
    Color and Shape:Solid
    Molecular weight:266.3

    Ref: TM-T33046

    100mg
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    500mg
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  • GSK2818713

    CAS:
    GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.
    Formula:C46H56N8O8
    Color and Shape:Solid
    Molecular weight:849.002

    Ref: TM-T38858

    5mg
    922.00€
  • Hirudin (54-65) (TFA)


    Hirudin (54-65) TFA, a segment of the 65-amino-acid protein Hirudin, exhibits anticoagulant properties [1].
    Color and Shape:Odour Solid

    Ref: TM-T82197

    5mg
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    50mg
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  • AL-611

    CAS:

    AL-611 is an HCV NS5B polymerase inhibitor ( EC 50 = 5 nM).

    Formula:C25H33F2N6O8P
    Color and Shape:Solid
    Molecular weight:614.544

    Ref: TM-T39082

    5mg
    922.00€
  • Sitagliptin fenilalanil hydrochloride

    CAS:
    Sitagliptin phenylalanine hydrochloride, a dipeptidyl peptidase-4 (DPP-4) inhibitor [1], is a chemical compound utilized in medical applications.
    Formula:C25H25ClF6N6O2
    Color and Shape:Solid
    Molecular weight:590.95

    Ref: TM-T74592

    2mg
    85.00€
  • AMG-222

    CAS:
    AMG-222 (ALS-2-0426, ALS-20426) is a DPP-4 inhibitor and may be used in the treatment of type 2 diabetes.
    Formula:C32H39N9O3
    Color and Shape:Solid
    Molecular weight:597.71

    Ref: TM-T29970

    25mg
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    50mg
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    100mg
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  • Histatin 5 TFA


    Histatin 5 TFA effectively inhibits host matrix metalloproteinases (MMP-2) and (MMP-9), demonstrating inhibition concentrations (IC 50s) of 0.57 μM and 0.25 μM
    Formula:C135H196N51F3O35
    Color and Shape:Solid
    Molecular weight:3150.31

    Ref: TM-T75755

    5mg
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    50mg
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  • Cathepsin L-IN-3

    CAS:
    Cathepsin L-IN-3, a tripeptide-sized inhibitor of cathepsin L, effectively targets this specific enzyme.
    Formula:C41H49N7O4S
    Color and Shape:Solid
    Molecular weight:735.94

    Ref: TM-TP2558

    10mg
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    50mg
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