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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 986 products of "Proteases/Proteasome"

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  • Ac-PAL-AMC

    CAS:
    Ac-PAL-AMC is a β1i/LMP2-specific substrate that fluoresces when cleaved; useful for measuring immunoproteasome activity.
    Formula:C26H34N4O6
    Color and Shape:Solid
    Molecular weight:498.57

    Ref: TM-T37421

    1mg
    241.00€
    5mg
    945.00€
    10mg
    1,665.00€
  • Talabostat

    CAS:
    Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.
    Formula:C9H19BN2O3
    Color and Shape:Solid
    Molecular weight:214.07

    Ref: TM-T37861

    5mg
    100.00€
    10mg
    148.00€
    50mg
    545.00€
  • N-CBZ-Phe-Arg-AMC TFA


    N-CBZ-Phe-Arg-AMC TFA (Z-FR-AMC TFA) is a fluorescent substrate for serine proteases. assess the activity of trypsin, plasmin, and cathepsin.
    Formula:C35H37F3N6O8
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:726.7

    Ref: TM-T76010

    1mg
    52.00€
    5mg
    109.00€
    10mg
    160.00€
    25mg
    314.00€
    50mg
    498.00€
  • PROTAC CG167


    PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)
    Formula:C65H79N13O11S
    Color and Shape:Solid
    Molecular weight:1250.47

    Ref: TM-T205234

    10mg
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    50mg
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  • GSK2336805

    CAS:
    GSK-2336805, an HCV NS5A inhibitor, is effective against genotypes 1, 4, 5, and some of 6.
    Formula:C42H52N8O8
    Color and Shape:Solid
    Molecular weight:796.91

    Ref: TM-T27461

    25mg
    2,178.00€
    50mg
    2,862.00€
    100mg
    3,870.00€
  • 5-epi-Arvestonate A

    CAS:

    5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.

    Formula:C16H26O5
    Color and Shape:Solid
    Molecular weight:298.37

    Ref: TM-T75535

    5mg
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    50mg
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  • VD2173

    CAS:
    VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.
    Formula:C31H45N9O6S
    Color and Shape:Solid
    Molecular weight:671.81

    Ref: TM-T74390

    5mg
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    50mg
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  • Peptide 74

    CAS:
    Peptide 74 is a synthetic peptide. It also inhibits the activated form of this enzyme.
    Formula:C62H107N23O20S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1558.79

    Ref: TM-TP2335

    100mg
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    500mg
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  • NIM811

    CAS:
    NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.
    Formula:C62H111N11O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1202.635

    Ref: TM-T12226

    5mg
    To inquire
  • Phaeosphaone D

    CAS:
    Phaeosphaone D, a thiodiketopiperazine from Phaeosphaeria fuckelii fungus, inhibits mushroom tyrosinase (IC50 = 33.2 μM).
    Formula:C20H27N3O3S2
    Color and Shape:Solid
    Molecular weight:421.58

    Ref: TM-T75470

    5mg
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    50mg
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  • Z-Leu-Tyr-Chloromethylketone

    CAS:
    Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor [1].
    Formula:C24H29ClN2O5
    Color and Shape:Solid
    Molecular weight:460.95

    Ref: TM-T80103

    5mg
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    50mg
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  • S62798

    CAS:
    S62798 is a highly potent and selective compound that inhibits activated thrombin activatable fibrinolysis inhibitor (TAFIa) with an IC50 value of 6 mM.
    Formula:C20H28FN4O4P
    Color and Shape:Solid
    Molecular weight:438.44

    Ref: TM-T39551

    5mg
    873.00€
  • Ecallantide TFA


    Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention of
    Color and Shape:Odour Solid

    Ref: TM-T82510

    5mg
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    50mg
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  • Lysine 4-nitroanilide

    CAS:
    Lysine 4-nitroanilide is a bioactive chemical.
    Formula:C12H18N4O3
    Color and Shape:Solid
    Molecular weight:266.3

    Ref: TM-T33046

    100mg
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    500mg
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  • JC-10

    CAS:
    JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe.
    Formula:C25H29Cl2IN4
    Purity:95%
    Color and Shape:Solid
    Molecular weight:583.34

    Ref: TM-TD0056

    1mg
    118.00€
  • Histatin 5 TFA


    Histatin 5 TFA effectively inhibits host matrix metalloproteinases (MMP-2) and (MMP-9), demonstrating inhibition concentrations (IC 50s) of 0.57 μM and 0.25 μM
    Formula:C135H196N51F3O35
    Color and Shape:Solid
    Molecular weight:3150.31

    Ref: TM-T75755

    5mg
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    50mg
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  • AMG-222

    CAS:
    AMG-222 (ALS-2-0426, ALS-20426) is a DPP-4 inhibitor and may be used in the treatment of type 2 diabetes.
    Formula:C32H39N9O3
    Color and Shape:Solid
    Molecular weight:597.71

    Ref: TM-T29970

    25mg
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    50mg
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    100mg
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  • KKI-5

    CAS:

    KKI 5: Serine protease inhibitor, blocks kallikrein & plasmin, potential for cancer therapy & angioedema treatment.

    Formula:C35H55N11O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:773.88

    Ref: TM-TP1792

    1mg
    64.00€
    5mg
    172.00€
    10mg
    299.00€
  • FFAGLDD TFA


    FFAGLDD TFA: MMP9 peptide for controlled DOX delivery to cytoplasm.
    Formula:C39H50F3N7O14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:897.85

    Ref: TM-TP1498

    100mg
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    500mg
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  • Cathepsin L-IN-3

    CAS:
    Cathepsin L-IN-3, a tripeptide-sized inhibitor of cathepsin L, effectively targets this specific enzyme.
    Formula:C41H49N7O4S
    Color and Shape:Solid
    Molecular weight:735.94

    Ref: TM-TP2558

    10mg
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    50mg
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