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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • MMP-9/MMP-13 Inhibitor I

    CAS:
    <p>MMP-9/MMP-13 Inhibitor I is a dual inhibitor of MMP-9 and MMP-13 with IC50 of both 0.9 nM.</p>
    Formula:C25H25N3O6S
    Color and Shape:Solid
    Molecular weight:495.55
  • 15,16-Dihydrotanshindiol C


    <p>15,16-Dihydrotanshindiol C is a useful organic compound for research related to life sciences and the catalog number is T123985.</p>
    Formula:C18H18O5
    Color and Shape:Solid
    Molecular weight:314.337
  • Grazoprevir potassium salt

    CAS:
    <p>Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.</p>
    Formula:C38H49KN6O9S
    Color and Shape:Solid
    Molecular weight:805
  • RXP470

    CAS:
    <p>RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).</p>
    Formula:C35H35BrClN4O10P
    Color and Shape:Solid
    Molecular weight:818
  • 6,6′-Dihydroxythiobinupharidine

    CAS:
    <p>6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-fold</p>
    Formula:C30H42N2O4S
    Color and Shape:Solid
    Molecular weight:526.73
  • Ac-PAL-AMC

    CAS:
    <p>Ac-PAL-AMC is a β1i/LMP2-specific substrate that fluoresces when cleaved; useful for measuring immunoproteasome activity.</p>
    Formula:C26H34N4O6
    Color and Shape:Solid
    Molecular weight:498.57
  • Tyrosinase-IN-38


    <p>Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.</p>
    Color and Shape:Odour Solid
  • SFTI-1

    CAS:
    <p>SFTI-1, a cyclic peptide trypsin inhibitor comprising 14 amino acid residues, is a potent Bowman-Birk inhibitor.</p>
    Formula:C67H104N18O18S2
    Color and Shape:Solid
    Molecular weight:1513.78
  • PROTAC CG167


    <p>PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)</p>
    Formula:C65H79N13O11S
    Color and Shape:Solid
    Molecular weight:1250.47
  • FFAGLDD TFA


    <p>FFAGLDD TFA: MMP9 peptide for controlled DOX delivery to cytoplasm.</p>
    Formula:C39H50F3N7O14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:897.85
  • 5-epi-Arvestonate A

    CAS:
    <p>5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.</p>
    Formula:C16H26O5
    Color and Shape:Solid
    Molecular weight:298.37
  • VD2173

    CAS:
    <p>VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.</p>
    Formula:C31H45N9O6S
    Color and Shape:Solid
    Molecular weight:671.81
  • Bortezomib analog


    <p>Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.</p>
    Color and Shape:Odour Solid
  • NIM811

    CAS:
    <p>NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.</p>
    Formula:C62H111N11O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1202.635
  • Pentosan Polysulfate

    CAS:
    <p>Pentosan Polysulfate: anti-HIV, anti-inflammatory, supports cartilage, treats interstitial cystitis.</p>
    Purity:98%
    Color and Shape:Solid
    Molecular weight:N/A
  • Rivulariapeptolides 1155


    <p>Rivulariapeptolides 1155 inhibits chymotrypsin (41.84 nM), elastase (4.94 nM), and proteinase K (56.54 nM).</p>
    Formula:C59H81N9O15
    Color and Shape:Solid
    Molecular weight:1156.33
  • CP-346086 dihydrate

    CAS:
    <p>CP-346086 dihydrate is a strong oral MTP inhibitor with 2.0 nM IC50, reducing cholesterol and triglycerides in vivo.</p>
    Formula:C26H26F3N5O3
    Color and Shape:Solid
    Molecular weight:513.521
  • Cathepsin L-IN-3

    CAS:
    <p>Cathepsin L-IN-3, a tripeptide-sized inhibitor of cathepsin L, effectively targets this specific enzyme.</p>
    Formula:C41H49N7O4S
    Color and Shape:Solid
    Molecular weight:735.94
  • Anticancer agent 114


    <p>Anticancer agent 114: oral dipeptide boronic acid, proteasome inhibitor, IC 50 = 2.2 nM, halts RPMI-8226 cell growth, for multiple myeloma research.</p>
    Formula:C28H33BF6N2O7
    Color and Shape:Solid
    Molecular weight:634.37
  • ADAM8-IN-1

    CAS:
    <p>ADAM8-IN-1 is a potent ADAM8 inhibitor with an IC 50 value of 73 nM.</p>
    Formula:C44H44Br4N6O12S2
    Color and Shape:Solid
    Molecular weight:1232.6