
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(34 products)
- Cysteine Protease(96 products)
- DPP-4(20 products)
- Glutaminase(40 products)
- HIV Protease(447 products)
- PAI-1(25 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(94 products)
- Serine Protease(50 products)
- p97(14 products)
Show 3 more subcategories
Found 1045 products of "Proteases/Proteasome"
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MMP-9/MMP-13 Inhibitor I
CAS:<p>MMP-9/MMP-13 Inhibitor I is a dual inhibitor of MMP-9 and MMP-13 with IC50 of both 0.9 nM.</p>Formula:C25H25N3O6SColor and Shape:SolidMolecular weight:495.5515,16-Dihydrotanshindiol C
<p>15,16-Dihydrotanshindiol C is a useful organic compound for research related to life sciences and the catalog number is T123985.</p>Formula:C18H18O5Color and Shape:SolidMolecular weight:314.337Grazoprevir potassium salt
CAS:<p>Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.</p>Formula:C38H49KN6O9SColor and Shape:SolidMolecular weight:805RXP470
CAS:<p>RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).</p>Formula:C35H35BrClN4O10PColor and Shape:SolidMolecular weight:8186,6′-Dihydroxythiobinupharidine
CAS:<p>6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-fold</p>Formula:C30H42N2O4SColor and Shape:SolidMolecular weight:526.73Ac-PAL-AMC
CAS:<p>Ac-PAL-AMC is a β1i/LMP2-specific substrate that fluoresces when cleaved; useful for measuring immunoproteasome activity.</p>Formula:C26H34N4O6Color and Shape:SolidMolecular weight:498.57Tyrosinase-IN-38
<p>Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.</p>Color and Shape:Odour SolidSFTI-1
CAS:<p>SFTI-1, a cyclic peptide trypsin inhibitor comprising 14 amino acid residues, is a potent Bowman-Birk inhibitor.</p>Formula:C67H104N18O18S2Color and Shape:SolidMolecular weight:1513.78PROTAC CG167
<p>PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)</p>Formula:C65H79N13O11SColor and Shape:SolidMolecular weight:1250.47FFAGLDD TFA
<p>FFAGLDD TFA: MMP9 peptide for controlled DOX delivery to cytoplasm.</p>Formula:C39H50F3N7O14Purity:98%Color and Shape:SolidMolecular weight:897.855-epi-Arvestonate A
CAS:<p>5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.</p>Formula:C16H26O5Color and Shape:SolidMolecular weight:298.37VD2173
CAS:<p>VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.</p>Formula:C31H45N9O6SColor and Shape:SolidMolecular weight:671.81Bortezomib analog
<p>Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.</p>Color and Shape:Odour SolidNIM811
CAS:<p>NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.</p>Formula:C62H111N11O12Purity:98%Color and Shape:SolidMolecular weight:1202.635Pentosan Polysulfate
CAS:<p>Pentosan Polysulfate: anti-HIV, anti-inflammatory, supports cartilage, treats interstitial cystitis.</p>Purity:98%Color and Shape:SolidMolecular weight:N/ARivulariapeptolides 1155
<p>Rivulariapeptolides 1155 inhibits chymotrypsin (41.84 nM), elastase (4.94 nM), and proteinase K (56.54 nM).</p>Formula:C59H81N9O15Color and Shape:SolidMolecular weight:1156.33CP-346086 dihydrate
CAS:<p>CP-346086 dihydrate is a strong oral MTP inhibitor with 2.0 nM IC50, reducing cholesterol and triglycerides in vivo.</p>Formula:C26H26F3N5O3Color and Shape:SolidMolecular weight:513.521Cathepsin L-IN-3
CAS:<p>Cathepsin L-IN-3, a tripeptide-sized inhibitor of cathepsin L, effectively targets this specific enzyme.</p>Formula:C41H49N7O4SColor and Shape:SolidMolecular weight:735.94Anticancer agent 114
<p>Anticancer agent 114: oral dipeptide boronic acid, proteasome inhibitor, IC 50 = 2.2 nM, halts RPMI-8226 cell growth, for multiple myeloma research.</p>Formula:C28H33BF6N2O7Color and Shape:SolidMolecular weight:634.37ADAM8-IN-1
CAS:<p>ADAM8-IN-1 is a potent ADAM8 inhibitor with an IC 50 value of 73 nM.</p>Formula:C44H44Br4N6O12S2Color and Shape:SolidMolecular weight:1232.6

