
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(38 products)
- Cysteine Protease(111 products)
- DPP-4(27 products)
- Glutaminase(46 products)
- HIV Protease(506 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(55 products)
- Proteasome(86 products)
- Serine Protease(54 products)
- p97(15 products)
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Found 985 products of "Proteases/Proteasome"
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RJS308
RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)Formula:C63H75N13O11SColor and Shape:SolidMolecular weight:1222.42Hepcidin-1 (mouse)
CAS:Hepcidin-1 (mouse) is a peptide hormone that regulates iron balance, elevates mRNA for TRAP, cathepsin K, and MMP-9, and promotes TRAP-5b protein secretion.Formula:C111H169N31O35S8Color and Shape:SolidMolecular weight:2754.24Fibrinogen-Binding Peptide
CAS:Fibrinogen-binding peptide mimics vitronectin site and activates platelets; thrombin turns it to fibrin.Formula:C25H39N7O8Purity:98%Color and Shape:SolidMolecular weight:565.62Nostosin G
Nostosin G, a linear peptide with Hpla, Hty, and argininal, inhibits trypsin effectively (IC50 = 0.1 μM).Formula:C25H33N5O6Color and Shape:SolidMolecular weight:499.56N-CBZ-Phe-Arg-AMC TFA
N-CBZ-Phe-Arg-AMC TFA (Z-FR-AMC TFA) is a fluorescent substrate for serine proteases. assess the activity of trypsin, plasmin, and cathepsin.Formula:C35H37F3N6O8Purity:99.88%Color and Shape:SolidMolecular weight:726.7α 1 Antichymotrypsin, Human Plasma
CAS:Alpha 1 Antichymotrypsin, Human Plasma is an inhibitor of serine proteases. This compound is present in amyloid lesions associated with Alzheimer's disease and can be utilized in Alzheimer's research.Color and Shape:SolidAL-611
CAS:AL-611 is an HCV NS5B polymerase inhibitor ( EC 50 = 5 nM).
Formula:C25H33F2N6O8PColor and Shape:SolidMolecular weight:614.544Plasma kallikrein-IN-1
CAS:Plasma kallikrein-IN-1 is a PKK inhibitor with an IC 50 value of 0.5 nM.Formula:C23H25F2N7OColor and Shape:SolidMolecular weight:453.498(-)-Taxifolin
CAS:(-)-Taxifolin, less active enantiomer with anti-tyrosinase, collagenase inhibition (IC50 = 193.3 μM), antifibrotic, antioxidant properties.Formula:C15H12O7Color and Shape:SolidMolecular weight:304.25Ellipyrone A
Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).Formula:C25H34O8Color and Shape:SolidMolecular weight:462.53Ac-DEMEEC-OH
CAS:Ac-DEMEEC-OH is a competitive inhibitor of the HCV NS3 protease with a Ki of 0.6 µM.Formula:C29H44N6O16S2Color and Shape:SolidMolecular weight:796.82CL 82198 hydrochloride
CAS:CL 82198 hydrochloride selectively inhibits MMP-13, not MMP-1/9/TACE, and blocks HP75 invasion and neurotoxicity in zebrafish.Formula:C17H23ClN2O3Color and Shape:SolidMolecular weight:338.83Sadopeptins B
Sadopeptins B, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].Formula:C48H69N9O13SColor and Shape:SolidMolecular weight:1012.18Cathepsin K inhibitor 7
Cathepsin K Inhibitor7 (compound 7) is an inhibitor of Cathepsin K, exhibiting a pKi value of 7.3. It is utilized in research on osteoporosis.Color and Shape:Odour SolidHistargin
CAS:Histargin is an enzyme inhibitor separated from Streptomyces roseoviridis.Formula:C14H25N7O4Color and Shape:SolidMolecular weight:355.39DPP8/9-IN-1
DPP8/9-IN-1 (Compound 16) is a selective covalent inhibitor of dipeptidyl peptidase 8 and 9 (DPP8/9), with IC50 values of 14 nM and 298 nM, respectively. It irreversibly binds to the active site serine (such as S730 in DPP9) through a phosphate ester warhead, blocking substrate binding and inhibiting DPP8/9-mediated protein processing. DPP8/9-IN-1 holds potential for research in cancer and inflammatory diseases.Color and Shape:Odour SolidMMP-9/MMP-13 Inhibitor I
CAS:MMP-9/MMP-13 Inhibitor I is a dual inhibitor of MMP-9 and MMP-13 with IC50 of both 0.9 nM.Formula:C25H25N3O6SColor and Shape:SolidMolecular weight:495.55Enzyme-IN-1
CAS:Enzyme-IN-1(compound 1)为基于肽的N端亲核试剂(Ntn)水解酶抑制剂,特别针对20S蛋白酶体的糜胰蛋白酶样活性(CT-L)进行抑制,可能展现出抗炎特性。Formula:C36H50N4O7Color and Shape:SolidMolecular weight:650.8Activated Protein C (390-404), human
CAS:Human Activated Protein C (390-404) peptide derived from serine protease, suppresses APC anticoagulation.Formula:C91H130N22O23Purity:98%Color and Shape:SolidMolecular weight:1900.14KKI-5
CAS:KKI 5: Serine protease inhibitor, blocks kallikrein & plasmin, potential for cancer therapy & angioedema treatment.
Formula:C35H55N11O9Purity:98%Color and Shape:SolidMolecular weight:773.88

