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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 985 products of "Proteases/Proteasome"

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  • RJS308


    RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)
    Formula:C63H75N13O11S
    Color and Shape:Solid
    Molecular weight:1222.42

    Ref: TM-T205591

    10mg
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    50mg
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  • Hepcidin-1 (mouse)

    CAS:
    Hepcidin-1 (mouse) is a peptide hormone that regulates iron balance, elevates mRNA for TRAP, cathepsin K, and MMP-9, and promotes TRAP-5b protein secretion.
    Formula:C111H169N31O35S8
    Color and Shape:Solid
    Molecular weight:2754.24

    Ref: TM-T80108

    5mg
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    50mg
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  • Fibrinogen-Binding Peptide

    CAS:
    Fibrinogen-binding peptide mimics vitronectin site and activates platelets; thrombin turns it to fibrin.
    Formula:C25H39N7O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:565.62

    Ref: TM-TP1736

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    500mg
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  • Nostosin G


    Nostosin G, a linear peptide with Hpla, Hty, and argininal, inhibits trypsin effectively (IC50 = 0.1 μM).
    Formula:C25H33N5O6
    Color and Shape:Solid
    Molecular weight:499.56

    Ref: TM-T75647

    5mg
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    50mg
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  • N-CBZ-Phe-Arg-AMC TFA


    N-CBZ-Phe-Arg-AMC TFA (Z-FR-AMC TFA) is a fluorescent substrate for serine proteases. assess the activity of trypsin, plasmin, and cathepsin.
    Formula:C35H37F3N6O8
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:726.7

    Ref: TM-T76010

    1mg
    52.00€
    5mg
    109.00€
    10mg
    160.00€
    25mg
    314.00€
    50mg
    498.00€
  • α 1 Antichymotrypsin, Human Plasma

    CAS:
    Alpha 1 Antichymotrypsin, Human Plasma is an inhibitor of serine proteases. This compound is present in amyloid lesions associated with Alzheimer's disease and can be utilized in Alzheimer's research.
    Color and Shape:Solid

    Ref: TM-TP3129

    10mg
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    50mg
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  • AL-611

    CAS:

    AL-611 is an HCV NS5B polymerase inhibitor ( EC 50 = 5 nM).

    Formula:C25H33F2N6O8P
    Color and Shape:Solid
    Molecular weight:614.544

    Ref: TM-T39082

    5mg
    922.00€
  • Plasma kallikrein-IN-1

    CAS:
    Plasma kallikrein-IN-1 is a PKK inhibitor with an IC 50 value of 0.5 nM.
    Formula:C23H25F2N7O
    Color and Shape:Solid
    Molecular weight:453.498

    Ref: TM-T40312

    5mg
    873.00€
  • (-)-Taxifolin

    CAS:
    (-)-Taxifolin, less active enantiomer with anti-tyrosinase, collagenase inhibition (IC50 = 193.3 μM), antifibrotic, antioxidant properties.
    Formula:C15H12O7
    Color and Shape:Solid
    Molecular weight:304.25

    Ref: TM-T38497

    25mg
    1,369.00€
  • Ellipyrone A


    Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).
    Formula:C25H34O8
    Color and Shape:Solid
    Molecular weight:462.53

    Ref: TM-T75492

    5mg
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    50mg
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  • Ac-DEMEEC-OH

    CAS:
    Ac-DEMEEC-OH is a competitive inhibitor of the HCV NS3 protease with a Ki of 0.6 µM.
    Formula:C29H44N6O16S2
    Color and Shape:Solid
    Molecular weight:796.82

    Ref: TM-TP2848

    10mg
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    50mg
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  • CL 82198 hydrochloride

    CAS:
    CL 82198 hydrochloride selectively inhibits MMP-13, not MMP-1/9/TACE, and blocks HP75 invasion and neurotoxicity in zebrafish.
    Formula:C17H23ClN2O3
    Color and Shape:Solid
    Molecular weight:338.83

    Ref: TM-T41179

    10mg
    642.00€
  • Sadopeptins B


    Sadopeptins B, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].
    Formula:C48H69N9O13S
    Color and Shape:Solid
    Molecular weight:1012.18

    Ref: TM-T75624

    5mg
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    50mg
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  • Cathepsin K inhibitor 7


    Cathepsin K Inhibitor7 (compound 7) is an inhibitor of Cathepsin K, exhibiting a pKi value of 7.3. It is utilized in research on osteoporosis.
    Color and Shape:Odour Solid

    Ref: TM-T89126

    10mg
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    50mg
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  • Histargin

    CAS:
    Histargin is an enzyme inhibitor separated from Streptomyces roseoviridis.
    Formula:C14H25N7O4
    Color and Shape:Solid
    Molecular weight:355.39

    Ref: TM-T25504

    25mg
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    100mg
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  • DPP8/9-IN-1


    DPP8/9-IN-1 (Compound 16) is a selective covalent inhibitor of dipeptidyl peptidase 8 and 9 (DPP8/9), with IC50 values of 14 nM and 298 nM, respectively. It irreversibly binds to the active site serine (such as S730 in DPP9) through a phosphate ester warhead, blocking substrate binding and inhibiting DPP8/9-mediated protein processing. DPP8/9-IN-1 holds potential for research in cancer and inflammatory diseases.
    Color and Shape:Odour Solid

    Ref: TM-T206718

    10mg
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    50mg
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  • MMP-9/MMP-13 Inhibitor I

    CAS:
    MMP-9/MMP-13 Inhibitor I is a dual inhibitor of MMP-9 and MMP-13 with IC50 of both 0.9 nM.
    Formula:C25H25N3O6S
    Color and Shape:Solid
    Molecular weight:495.55

    Ref: TM-T37172

    25mg
    740.00€
  • Enzyme-IN-1

    CAS:
    Enzyme-IN-1(compound 1)为基于肽的N端亲核试剂(Ntn)水解酶抑制剂,特别针对20S蛋白酶体的糜胰蛋白酶样活性(CT-L)进行抑制,可能展现出抗炎特性。
    Formula:C36H50N4O7
    Color and Shape:Solid
    Molecular weight:650.8

    Ref: TM-T74878

    5mg
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    50mg
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  • Activated Protein C (390-404), human

    CAS:
    Human Activated Protein C (390-404) peptide derived from serine protease, suppresses APC anticoagulation.
    Formula:C91H130N22O23
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1900.14

    Ref: TM-TP1628

    100mg
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    500mg
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  • KKI-5

    CAS:

    KKI 5: Serine protease inhibitor, blocks kallikrein & plasmin, potential for cancer therapy & angioedema treatment.

    Formula:C35H55N11O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:773.88

    Ref: TM-TP1792

    1mg
    64.00€
    5mg
    172.00€
    10mg
    299.00€