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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • Pentosan Polysulfate

    CAS:
    <p>Pentosan Polysulfate: anti-HIV, anti-inflammatory, supports cartilage, treats interstitial cystitis.</p>
    Purity:98%
    Color and Shape:Solid
    Molecular weight:N/A
  • MMP-3 Inhibitor acetate


    <p>MMP-3 Inhibitor acetate is a cell-permeable and potent inhibitor of human MMP-3.</p>
    Formula:C29H50N10O11S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:746.83
  • BMS-767778

    CAS:
    <p>BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.</p>
    Formula:C19H20Cl2N4O2
    Color and Shape:Solid
    Molecular weight:407.29
  • Tyrosinase-IN-34


    <p>Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.</p>
    Formula:C19H14BrClN4O
    Color and Shape:Solid
    Molecular weight:429.7
  • α 1(I) Collagen (614-639), human

    CAS:
    <p>This is a peptide inhibitor of collagen fibrillar matrix assembly.</p>
    Formula:C134H189N37O39
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2942.16
  • Apovincamine

    CAS:
    <p>Apovincamine is a vinca alkaloid and a chemical precursor of Vinpocetine, which is a derivative of Vincamine with vasodilating activity.</p>
    Formula:C21H24N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:336.44
  • Nitidanin


    <p>Nitidanin is a useful organic compound for research related to life sciences and the catalog number is T125599.</p>
    Formula:C21H24O8
    Color and Shape:Solid
    Molecular weight:404.415
  • NVP-DPP728 dihydrochloride

    CAS:
    <p>NVP-DPP728 dihydrochloride is a potent, selective DPP-IV inhibitor with a Ki of 11 nM, useful in diabetes research.</p>
    Formula:C15H20Cl2N6O
    Color and Shape:Solid
    Molecular weight:371.27
  • RJS308


    <p>RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)</p>
    Formula:C63H75N13O11S
    Color and Shape:Solid
    Molecular weight:1222.42
  • Stevia Powder


    <p>Stevia Powder, a natural sweetener, possesses antioxidant properties. It regulates antifibrotic pathways in cirrhotic rats, demonstrated by a reduction in hepatic stellate cells and decreased expression of matrix metalloproteinases MMP2 and MMP13. Furthermore, it increases the antifibrotic molecule Smad7, which helps prevent the elevation of serum necrosis and bile retention markers, thereby inhibiting the progression of liver fibrosis.</p>
    Color and Shape:Odour Solid
  • PR 39 (porcine) acetate


    <p>PR 39 (porcine) acetate is a noncompetitive, reversible and allosteric proteasome inhibitor.</p>
    Purity:98%
    Color and Shape:Liquid
    Molecular weight:N/A
  • 6-Acetylnimbandiol

    CAS:
    <p>6-Acetylnimbandiol, a non-toxic agent, inhibits tyrosinase (IC50=69.85 μM), melanin, and MITF; useful in melanoma studies.</p>
    Formula:C28H34O8
    Color and Shape:Solid
    Molecular weight:498.56
  • Isoleucylvaline

    CAS:
    <p>Isoleucylvaline is a dipeptide.</p>
    Formula:C11H22N2O3
    Color and Shape:Solid
    Molecular weight:230.30
  • PPACK II

    CAS:
    <p>PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor [1] .</p>
    Formula:C25H33ClN6O3
    Color and Shape:Solid
    Molecular weight:501.02
  • L 659286

    CAS:
    <p>L 659286 is one kind of cephalosporin derivative.</p>
    Formula:C17H21N5O7S2
    Color and Shape:Solid
    Molecular weight:471.51
  • Pseudostellarin G

    CAS:
    <p>Pseudostellarin G, a naturally occurring cyclo-octapeptide, exhibits inhibitory activity against tyrosinase and suppresses melanin production.</p>
    Formula:C42H56N8O9
    Color and Shape:Solid
    Molecular weight:816.94
  • Fotagliptin

    CAS:
    <p>Fotagliptin is a dipeptidyl peptidase IV inhibitor.</p>
    Formula:C17H19FN6O
    Color and Shape:Solid
    Molecular weight:342.37
  • Ellipyrone A


    <p>Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).</p>
    Formula:C25H34O8
    Color and Shape:Solid
    Molecular weight:462.53
  • PM 102

    CAS:
    <p>Peptide that reverses the anticoagulant effect of heparin. Potently binds heparin (Kd = 36 nM in vitro).</p>
    Formula:C235H425N111O64
    Purity:98%
    Color and Shape:Solid
    Molecular weight:5830
  • WYRGRL

    CAS:
    <p>WYRGRL is a peptide that targets collagen II α1 (collagen II α1) through binding interaction. This short chondro-targeting peptide sequence enhances the targeting efficiency of peptide-functionalized nanoplatforms for cartilage in vivo, increasing it by approximately 72 times.</p>
    Formula:C40H59N13O8
    Color and Shape:Solid
    Molecular weight:849.98