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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • Chetoseminudin B

    CAS:
    <p>Chetoseminudin B exhibits inhibitory activity against mushroom tyrosinase, with an IC 50 value of 31.7 μM [1].</p>
    Formula:C17H21N3O3S2
    Color and Shape:Solid
    Molecular weight:379.5
  • (-)-Taxifolin

    CAS:
    <p>(-)-Taxifolin, less active enantiomer with anti-tyrosinase, collagenase inhibition (IC50 = 193.3 μM), antifibrotic, antioxidant properties.</p>
    Formula:C15H12O7
    Color and Shape:Solid
    Molecular weight:304.25
  • Dazcapistat

    CAS:
    <p>Dazcapistat is a potent calpain inhibitor, with IC50s of &lt;3 μM for calpain 1, calpain 2 and calpain 9, respectively.</p>
    Formula:C21H18FN3O4
    Purity:99.11%
    Color and Shape:Solid
    Molecular weight:395.38
  • IETD-CHO TFA


    <p>IETD-CHO TFA (Caspase-8-IN-1) functions as a potent inhibitor of caspase-8 [1].</p>
    Formula:C95H162N20O26·xC2HF3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2000.42 (free acid)
  • Tripeptide-32

    CAS:
    <p>Tripeptide-32 is a bioactive peptide recognized for its anti-aging properties, commonly utilized as an ingredient in cosmetics [1].</p>
    Formula:C12H22N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:302.33
  • CTS-1027

    CAS:
    <p>CTS-1027 is a small molecule inhibitor of MMPs (IC50s: 0.3 nM, 0.5 nM for MMP2, MMP13). It has &gt; 1,000 fold selectivity over MMP1.</p>
    Formula:C19H20ClNO6S
    Color and Shape:Solid
    Molecular weight:425.88
  • Ilomastat

    CAS:
    Formula:C20H28N4O4
    Purity:>95.0%(HPLC)(qNMR)
    Color and Shape:White to Light yellow powder to crystal
    Molecular weight:388.47

    Ref: 3B-I1202

    10mg
    189.00€
  • Ubenimex Hydrochloride [for Biochemical Research]

    CAS:
    Formula:C16H24N2O4·HCl
    Purity:>97.0%(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:344.84

    Ref: 3B-B4000

    25mg
    196.00€
  • PSI-6206 13C,d3

    CAS:
    <p>PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is a potent and selective HCV NS5B polymerase inhibitor.</p>
    Formula:C10H13FN2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:264.23
  • Glutaminase-IN-3

    CAS:
    <p>Glutaminase-IN-3 is a potent Glutaminase 1 inhibitor with potential antitumor activity and inhibits GLS1 for cancer research.</p>
    Formula:C19H19F3N6O2S
    Purity:98.51%
    Color and Shape:Solid
    Molecular weight:452.45
  • BAY-677

    CAS:
    <p>BAY-677, an inactive counterpart to BAY-678, inhibits human neutrophil elastase with 20 nM IC50 and is an SGC-nominated probe.</p>
    Formula:C20H15F3N4O2
    Color and Shape:Solid
    Molecular weight:400.35
  • Thrombin inhibitor 5

    CAS:
    <p>Thrombin inhibitor 5 (compound 385), IC50: 0.1-1 μM, used in venous thromboembolism studies.</p>
    Formula:C11H9FN4O3
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:264.21
  • (Arg)9

    CAS:
    <p>(Arg)9 (Nona-L-arginine;Peptide R9) is a cell-penetrating peptide,and exhibits neuroprotective activity(IC50 of 0.78 μM, in the glutamic acid model).</p>
    Formula:C54H110N36O10
    Color and Shape:Solid
    Molecular weight:1423.69
  • Tilpisertib

    CAS:
    <p>Tilpisertib is a serine/threonine kinase inhibitor (WO2017007689).</p>
    Formula:C33H33ClN8O
    Color and Shape:Solid
    Molecular weight:593.13
  • H-Arg-4MβNA

    CAS:
    <p>H-Arg-4MβNA (H-Arg-4MbNA) is a peptide that serves as a substrate for cathepsin H. The enzyme activity is often detected in gel electrophoresis.</p>
    Formula:C17H23N5O2
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:329.4
  • Tomeglovir

    CAS:
    <p>Tomeglovir is a potent anti-CMV agent, inhibiting the processing of viral DNA-concatemers (IC50s: 0.34/0.039 μM for HCMV and MCMV).</p>
    Formula:C23H27N3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:441.54
  • PKSI-527

    CAS:
    <p>PKSI-527 inhibits plasma kallikrein (Ki=0.81μM), selective vs. glandular kallikrein/thrombin/urokinase/Xa, reduces bradykinin, affects clotting times.</p>
    Formula:C25H32ClN3O4
    Color and Shape:Solid
    Molecular weight:473.99
  • Saquinavir mesylate

    CAS:
    <p>Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapy</p>
    Formula:C39H54N6O8S
    Purity:99.19%
    Color and Shape:White Or Pale Yellow Powder
    Molecular weight:766.9
  • 5-Amino-8-hydroxyquinoline

    CAS:
    <p>5-Amino-8-hydroxyquinoline(5A8HQ),Proteasome inhibitor. Potential anticancer agent.</p>
    Formula:C9H8N2O
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:160.17
  • PD-166793

    CAS:
    <p>PD-166793 is an MMP inhibitor with inhibitory effects on MMP-2, MMP-3 and MMP-13.PD-166793 improves myocardial ischemia in a rat heart failure model.</p>
    Formula:C17H18BrNO4S
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:412.3