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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • Paritaprevir

    CAS:
    <p>Paritaprevir (ABT450) 是一种非结构蛋白 3/4A 蛋白酶抑制剂,对 HCV 1a 和 HCV 1b 的 EC50 值分别为 1 和 0.21 nM。它也是SARS-CoV 3CLpro 的抑制剂,IC50为 1.31 μM。</p>
    Formula:C40H43N7O7S
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:765.88
  • XMD16-5

    CAS:
    <p>XMD16-5 blocks TNK2, linked to advanced lung/prostate cancers and breast cancer metastasis in mice; disrupts signaling in several tumors.</p>
    Formula:C23H24N6O2
    Purity:98.89% - 99.98%
    Color and Shape:Solid
    Molecular weight:416.48
  • Sofosbuvir

    CAS:
    <p>Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment</p>
    Formula:C22H29FN3O9P
    Purity:99.77% - 99.82%
    Color and Shape:Solid
    Molecular weight:529.45
  • 4-Butylresorcinol

    CAS:
    <p>4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.</p>
    Formula:C10H14O2
    Purity:98.64% - ≥95%
    Color and Shape:Light Beige Solid Powder
    Molecular weight:166.22
  • Odanacatib

    CAS:
    <p>Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.</p>
    Formula:C25H27F4N3O3S
    Purity:98.53% - 99.53%
    Color and Shape:Solid
    Molecular weight:525.56
  • Ximelagatran

    CAS:
    <p>Ximelagatran, oral direct thrombin inhibitor, transforms to active melagatran in body.</p>
    Formula:C24H35N5O5
    Purity:95.48% - 99.60%
    Color and Shape:Solid
    Molecular weight:473.57
  • Daclatasvir dihydrochloride

    CAS:
    <p>Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; rare liver enzyme elevation, seldom causes jaundice.</p>
    Formula:C40H52Cl2N8O6
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:811.8
  • TAPI-1 trifluoroacetate (163847-77-6(free base))


    <p>TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.</p>
    Formula:C28H38F3N5O7
    Purity:98.06%
    Color and Shape:Solid
    Molecular weight:613.62
  • Elbasvir

    CAS:
    <p>Elbasvir (MK-8742) is an NS5A inhibitor developed for chronic HCV treatment.</p>
    Formula:C49H55N9O7
    Purity:98.95% - 99.85%
    Color and Shape:Solid
    Molecular weight:882.02
  • Ixazomib citrate

    CAS:
    <p>Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).</p>
    Formula:C20H23BCl2N2O9
    Purity:98.37% - >99.99%
    Color and Shape:Solid
    Molecular weight:517.12
  • Tegobuvir

    CAS:
    <p>Tegobuvir (GS 333126) is a specific and covalent HCV NS5B polymerase inhibitor.</p>
    Formula:C25H14F7N5
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:517.4
  • Voxilaprevir

    CAS:
    <p>Voxilaprevir is an inhibitor of hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease.</p>
    Formula:C40H52F4N6O9S
    Purity:99.83% - 99.93%
    Color and Shape:Solid
    Molecular weight:868.93
  • Grazoprevir

    CAS:
    <p>Grazoprevir (MK-5172) is a protease inhibitor targeting hepatitis C virus NS3/4A used for treating chronic HCV genotypes 1 or 4 infections. Cost-effective and quality-assured.</p>
    Formula:C38H50N6O9S
    Purity:99.36% - >99.99%
    Color and Shape:Solid
    Molecular weight:766.9
  • Ac-DEVD-AMC

    CAS:
    <p>Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .</p>
    Formula:C30H37N5O13
    Purity:98.20%
    Color and Shape:White Powder
    Molecular weight:675.64
  • 4-Phenoxybenzylamine

    CAS:
    <p>4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .</p>
    Formula:C13H13NO
    Purity:97.26%
    Color and Shape:Solid
    Molecular weight:199.25
  • (R)-MG-132

    CAS:
    <p>(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.</p>
    Formula:C26H41N3O5
    Purity:98.45%
    Color and Shape:Solid
    Molecular weight:475.62
  • Dolutegravir sodium

    CAS:
    <p>Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature</p>
    Formula:C20H18F2N3NaO5
    Purity:98% - 99.46%
    Color and Shape:Solid
    Molecular weight:441.36
  • Peptide T acetate(106362-32-7 free base)


    <p>Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120.</p>
    Formula:C37H59N9O18
    Purity:99.47%
    Color and Shape:Solid
    Molecular weight:917.91
  • CA-074 methyl ester

    CAS:
    <p>CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!</p>
    Formula:C19H31N3O6
    Purity:97.26% - 99.58%
    Color and Shape:Solid
    Molecular weight:397.47
  • Letermovir

    CAS:
    <p>Letermovir (AIC246) (AIC246) is a novel anti-CMV compound (EC50: about 5 nM in fibroblast cells). It targets the pUL56 subunit of the viral terminase complex.</p>
    Formula:C29H28F4N4O4
    Purity:99.85% - 99.87%
    Color and Shape:Solid
    Molecular weight:572.55