
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(34 products)
- Cysteine Protease(96 products)
- DPP-4(20 products)
- Glutaminase(40 products)
- HIV Protease(447 products)
- PAI-1(25 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(94 products)
- Serine Protease(50 products)
- p97(14 products)
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Found 1045 products of "Proteases/Proteasome"
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Paritaprevir
CAS:<p>Paritaprevir (ABT450) 是一种非结构蛋白 3/4A 蛋白酶抑制剂,对 HCV 1a 和 HCV 1b 的 EC50 值分别为 1 和 0.21 nM。它也是SARS-CoV 3CLpro 的抑制剂,IC50为 1.31 μM。</p>Formula:C40H43N7O7SPurity:99.72%Color and Shape:SolidMolecular weight:765.88XMD16-5
CAS:<p>XMD16-5 blocks TNK2, linked to advanced lung/prostate cancers and breast cancer metastasis in mice; disrupts signaling in several tumors.</p>Formula:C23H24N6O2Purity:98.89% - 99.98%Color and Shape:SolidMolecular weight:416.48Sofosbuvir
CAS:<p>Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment</p>Formula:C22H29FN3O9PPurity:99.77% - 99.82%Color and Shape:SolidMolecular weight:529.454-Butylresorcinol
CAS:<p>4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.</p>Formula:C10H14O2Purity:98.64% - ≥95%Color and Shape:Light Beige Solid PowderMolecular weight:166.22Odanacatib
CAS:<p>Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.</p>Formula:C25H27F4N3O3SPurity:98.53% - 99.53%Color and Shape:SolidMolecular weight:525.56Ximelagatran
CAS:<p>Ximelagatran, oral direct thrombin inhibitor, transforms to active melagatran in body.</p>Formula:C24H35N5O5Purity:95.48% - 99.60%Color and Shape:SolidMolecular weight:473.57Daclatasvir dihydrochloride
CAS:<p>Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; rare liver enzyme elevation, seldom causes jaundice.</p>Formula:C40H52Cl2N8O6Purity:99.67%Color and Shape:SolidMolecular weight:811.8TAPI-1 trifluoroacetate (163847-77-6(free base))
<p>TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.</p>Formula:C28H38F3N5O7Purity:98.06%Color and Shape:SolidMolecular weight:613.62Elbasvir
CAS:<p>Elbasvir (MK-8742) is an NS5A inhibitor developed for chronic HCV treatment.</p>Formula:C49H55N9O7Purity:98.95% - 99.85%Color and Shape:SolidMolecular weight:882.02Ixazomib citrate
CAS:<p>Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).</p>Formula:C20H23BCl2N2O9Purity:98.37% - >99.99%Color and Shape:SolidMolecular weight:517.12Tegobuvir
CAS:<p>Tegobuvir (GS 333126) is a specific and covalent HCV NS5B polymerase inhibitor.</p>Formula:C25H14F7N5Purity:99.21%Color and Shape:SolidMolecular weight:517.4Voxilaprevir
CAS:<p>Voxilaprevir is an inhibitor of hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease.</p>Formula:C40H52F4N6O9SPurity:99.83% - 99.93%Color and Shape:SolidMolecular weight:868.93Grazoprevir
CAS:<p>Grazoprevir (MK-5172) is a protease inhibitor targeting hepatitis C virus NS3/4A used for treating chronic HCV genotypes 1 or 4 infections. Cost-effective and quality-assured.</p>Formula:C38H50N6O9SPurity:99.36% - >99.99%Color and Shape:SolidMolecular weight:766.9Ac-DEVD-AMC
CAS:<p>Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .</p>Formula:C30H37N5O13Purity:98.20%Color and Shape:White PowderMolecular weight:675.644-Phenoxybenzylamine
CAS:<p>4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .</p>Formula:C13H13NOPurity:97.26%Color and Shape:SolidMolecular weight:199.25(R)-MG-132
CAS:<p>(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.</p>Formula:C26H41N3O5Purity:98.45%Color and Shape:SolidMolecular weight:475.62Dolutegravir sodium
CAS:<p>Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature</p>Formula:C20H18F2N3NaO5Purity:98% - 99.46%Color and Shape:SolidMolecular weight:441.36Peptide T acetate(106362-32-7 free base)
<p>Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120.</p>Formula:C37H59N9O18Purity:99.47%Color and Shape:SolidMolecular weight:917.91CA-074 methyl ester
CAS:<p>CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!</p>Formula:C19H31N3O6Purity:97.26% - 99.58%Color and Shape:SolidMolecular weight:397.47Letermovir
CAS:<p>Letermovir (AIC246) (AIC246) is a novel anti-CMV compound (EC50: about 5 nM in fibroblast cells). It targets the pUL56 subunit of the viral terminase complex.</p>Formula:C29H28F4N4O4Purity:99.85% - 99.87%Color and Shape:SolidMolecular weight:572.55
