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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • Ixazomib

    CAS:
    <p>Ixazomib (MLN2238) is a boron-based peptide proteasome inhibitor targeting β5 site (IC50: 3.4 nM), also affecting β1 and β2 sites.</p>
    Formula:C14H19BCl2N2O4
    Purity:98% - 98.92%
    Color and Shape:Solid
    Molecular weight:361.03
  • Batimastat

    CAS:
    <p>Batimastat (BB94) (BB-94) is an effective, broad-spectrum matrix metalloprotease (MMP) inhibitor.</p>
    Formula:C23H31N3O4S2
    Purity:98.15% - 99.5%
    Color and Shape:Solid
    Molecular weight:477.64
  • Elvitegravir

    CAS:
    <p>Elvitegravir (JTK-303) is an HIV integrase inhibitor and CYP2C9 inducer.</p>
    Formula:C23H23ClFNO5
    Purity:98.43% - 99.57%
    Color and Shape:Solid
    Molecular weight:447.88
  • Telaprevir

    CAS:
    <p>Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).</p>
    Formula:C36H53N7O6
    Purity:96.9% - 98.89%
    Color and Shape:Solid
    Molecular weight:679.85
  • 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride

    CAS:
    <p>4-Chloro-2-(trifluoroacetyl)aniline hydrochloride is an inhibitor of HIV-1 RT (HIV reverse transcriptase) .</p>
    Formula:C8H6Cl2F3NO
    Purity:97.15%
    Color and Shape:Solid
    Molecular weight:260.04
  • Ceritinib

    CAS:
    <p>Ceritinib (LDK378) is an ALK inhibitor with selective, ATP-competitive, and oral activity. Ceritinib has antitumor activity. Cost-effective and quality-assured.</p>
    Formula:C28H36ClN5O3S
    Purity:98.52% - 99.77%
    Color and Shape:Solid
    Molecular weight:558.14
  • CGS 27023A

    CAS:
    <p>CGS 27023A is a non-peptidic, potent, and orally active stromelysin inhibitor.</p>
    Formula:C18H24ClN3O5S
    Purity:99.08%
    Color and Shape:Solid
    Molecular weight:429.92
  • Picolamine

    CAS:
    <p>Picolamine acts as a potential inhibitor of DPP-4.</p>
    Formula:C6H8N2
    Purity:98.3%
    Color and Shape:Light Yellow Liquid
    Molecular weight:108.14
  • SB-3CT

    CAS:
    <p>SB-3CT is a potent and specific gelatinase inhibitor for MMP-2(Ki=13.9 nM) and MMP-9(Ki=600 nM).</p>
    Formula:C15H14O3S2
    Purity:98% - 99.38%
    Color and Shape:Solid
    Molecular weight:306.4
  • S-methyl-KE-298

    CAS:
    <p>S-methyl-KE-298 is the second main metabolite in plasma,is a methyl conjugate of deacetyl-KE-298.KE-298 inhibits matrix metalloproteinase (MMP-1) production</p>
    Formula:C13H16O3S
    Purity:97.33%
    Color and Shape:Solid
    Molecular weight:252.33
  • Tenofovir alafenamide hemifumarate

    CAS:
    <p>Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir.</p>
    Formula:C21H29N6O5PC4H4O4
    Purity:99.33% - 99.96%
    Color and Shape:Solid
    Molecular weight:534.51
  • Trelagliptin succinate

    CAS:
    <p>Trelagliptin succinate (SYR-472 succinate) is a long-acting inhibitor of dipeptidyl peptidase-4 (DPP-4), being developed for the treatment of type 2 diabetes (</p>
    Formula:C22H26FN5O6
    Purity:99.27% - 99.92%
    Color and Shape:Solid
    Molecular weight:475.47
  • Ilomastat

    CAS:
    <p>Ilomastat (GM6001) (GM6001, Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor.</p>
    Formula:C20H28N4O4
    Purity:97.04% - 99.51%
    Color and Shape:Solid
    Molecular weight:388.46
  • 2-Benzylsuccinic acid

    CAS:
    <p>2-Benzylsuccinic acid (DL-Benzylsuccinic acid) is a bacterial xenobiotic metabolite.</p>
    Formula:C11H12O4
    Purity:99.01% - ≥95%
    Color and Shape:Solid
    Molecular weight:208.21
  • (R)-MG-132

    CAS:
    <p>(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.</p>
    Formula:C26H41N3O5
    Purity:98.45%
    Color and Shape:Solid
    Molecular weight:475.62
  • NBD-557

    CAS:
    <p>NBD-557 is a potentially HIV-1 inhibitor.</p>
    Formula:C17H24BrN3O2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:382.3
  • Sofosbuvir

    CAS:
    <p>Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment</p>
    Formula:C22H29FN3O9P
    Purity:99.77% - 99.82%
    Color and Shape:Solid
    Molecular weight:529.45
  • Vesnarinone

    CAS:
    <p>Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but</p>
    Formula:C22H25N3O4
    Purity:96.69% - 98.13%
    Color and Shape:Solid
    Molecular weight:395.45
  • Lersivirine

    CAS:
    <p>Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.</p>
    Formula:C17H18N4O2
    Purity:98.01%
    Color and Shape:Solid
    Molecular weight:310.35
  • Boceprevir

    CAS:
    <p>Boceprevir (SCH 503034), an oral HCV NS3 protease inhibitor, has a Ki of 14 nM and EC90 of 350 nM.</p>
    Formula:C27H45N5O5
    Purity:95% - 99.16%
    Color and Shape:Solid
    Molecular weight:519.68