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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • Trovirdine

    CAS:
    <p>Trovirdine (LY300046) is a thiourea non-nucleoside reverse transcriptase inhibitor.</p>
    Formula:C13H13BrN4S
    Purity:98.12% - 98.50%
    Color and Shape:Solid
    Molecular weight:337.24
  • HCV-IN-31

    CAS:
    <p>HCV-IN-31 is a HCV inhibitor with an EC50/EC95 of 15.7 μM.</p>
    Formula:C12H17FN6O3
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:312.3
  • VCH-916

    CAS:
    <p>VCH-916 is a new nonnucleoside inhibitor of HCV NS5B polymerase.</p>
    Formula:C26H36KNO4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:497.73
  • 2-PMPA

    CAS:
    <p>2-PMPA (2-(Phosphonomethyl)pentanedioic acid) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) (IC50=300 pM).</p>
    Formula:C6H11O7P
    Purity:97.4% - 99.5%
    Color and Shape:Solid
    Molecular weight:226.12
  • Bz-RS-ISer(3-Ph)-Ome

    CAS:
    <p>Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle.</p>
    Formula:C17H17NO4
    Purity:99.36% - 99.89%
    Color and Shape:White Crystal
    Molecular weight:299.32
  • Ledipasvir (acetone)

    CAS:
    <p>Ledipasvir (acetone) (GS-5885 acetone) is an HCV NS5A polymerase inhibitor, used for the treatment of hepatitis C virus infection.</p>
    Formula:C52H60F2N8O7
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:947.08
  • (R)-Trolox

    CAS:
    <p>(R)-Trolox is a selective tyrosinase inhibitor used in food, cosmetics, and pharmaceutical products.</p>
    Formula:C14H18O4
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:250.29
  • (1S,2R)-Alicapistat

    CAS:
    <p>(1S,2R)-Alicapistat inhibits calpains 1 and 2, shows promise for Alzheimer's, and has an IC50 of 395 nM.</p>
    Formula:C25H27N3O4
    Purity:99.60%
    Color and Shape:Soild
    Molecular weight:433.5
  • KP-457

    CAS:
    <p>KP-457 is a ADAM17 and a TNFα converting enzyme TACE inhibitor that blocks the production of soluble TNF (sTNF).</p>
    Formula:C21H24N2O7S2
    Purity:98.33%
    Color and Shape:Solid
    Molecular weight:480.56
  • Rilpivirine HCl

    CAS:
    <p>Rilpivirine HCl (Rilpivirine hydrochloride) is an NNRTI inhibitor with antiviral activity that inhibits the HIV virus.</p>
    Formula:C22H19ClN6
    Purity:99.48%
    Color and Shape:Solid
    Molecular weight:402.88
  • Teneligliptin

    CAS:
    <p>Teneligliptin (MP-513), potent DPP-4 inhibitor, IC50 ~1 nM, blocks DPP-4 in human/rat plasma and recombinant forms.</p>
    Formula:C22H30N6OS
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:426.58
  • Methylchloroisothiazolinone/Methylisothiazolinone Mixture

    CAS:
    <p>Methylchloroisothiazolinone/Methylisothiazolinone Mixture (Kathon 886MW),a preservative, activates MMPs in human bronchial epithelial cells.</p>
    Formula:C8H9ClN2O2S2
    Color and Shape:Solid
    Molecular weight:264.75
  • Sitagliptin phosphate monohydrate

    CAS:
    <p>Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.</p>
    Formula:C16H15F6N5O·H3PO4·H2O
    Purity:99.85% - 99.98%
    Color and Shape:White Or Almost White Crystalline Powder
    Molecular weight:523.33
  • Ledipasvir

    CAS:
    <p>Ledipasvir (GS-5885) is a Hepatitis C Virus NS5A Inhibitor.</p>
    Formula:C49H54F2N8O6
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:889
  • Nelfinavir

    CAS:
    <p>Nelfinavir (AG1341), with Ki=2 nM, is an HIV treatment and broad-spectrum anticancer drug.</p>
    Formula:C32H45N3O4S
    Purity:98.16% - 99.5%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:567.78
  • PSI

    CAS:
    <p>PSI is a proteasome inhibitor.</p>
    Formula:C32H50N4O8
    Purity:97% - 98.33%
    Color and Shape:Solid
    Molecular weight:618.76
  • Danoprevir

    CAS:
    <p>Danoprevir (RG7227) is a peptidomimetic inhibitor of the NS3/4A protease(IC50=0.2-3.5 nM) of hepatitis C virus (HCV).</p>
    Formula:C35H46FN5O9S
    Purity:98% - 99.35%
    Color and Shape:Solid
    Molecular weight:731.83
  • Triton X-45(n=4)

    CAS:
    <p>Triton X-45: nonionic, low HLB surfactant, dispersible in water, high Krafft point, relevant for HCV research.</p>
    Formula:C22H38O5
    Color and Shape:Solid
    Molecular weight:382.53
  • Lanadelumab

    CAS:
    <p>Lanadelumab (SHP643), a humanized IgG1 antibody, inhibits plasma kallikrein and its interaction with HMWK, supporting hereditary angioedema research.</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • KZR-504

    CAS:
    KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 nM, 4.274 μM for LMP2 and LMP7, respectively).
    Formula:C21H23N3O6
    Color and Shape:Solid
    Molecular weight:413.42