
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(38 products)
- Cysteine Protease(111 products)
- DPP-4(27 products)
- Glutaminase(46 products)
- HIV Protease(508 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(55 products)
- Proteasome(86 products)
- Serine Protease(54 products)
- p97(15 products)
Show 3 more subcategories
Found 981 products of "Proteases/Proteasome"
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AGLME
CAS:AGLME is used in a direct enzymatic assay for activated Hageman factor measuring the ability of Hageman factor to hydrolyze the cpd.Formula:C11H21N3O4Color and Shape:SolidMolecular weight:259.3Chymase-IN-1
CAS:Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM).Formula:C20H15ClNO4PSPurity:99.17%Color and Shape:SolidMolecular weight:431.83Ref: TM-T10811
1mg146.00€5mg349.00€1mL*10mM (DMSO)384.00€10mg497.00€25mg745.00€50mg999.00€100mg1,341.00€500mg2,655.00€TAPI-0
CAS:TAPI-0 is a matrix metalloprotease (MMP) and TACE inhibitor.Formula:C24H32N4O5Color and Shape:SolidMolecular weight:456.53ADAMTS-5-IN-2
CAS:ADAMTS-5-IN-2 is a potent inhibitor of ADAMTS-5, exhibiting an IC50 of 0.71 µM, and holds potential for osteoarthritis research.Formula:C17H15N3OSColor and Shape:SolidMolecular weight:309.39SJA6017
CAS:SJA6017: inhibits calpain-1/2, cathepsins B/L; prevents apoptosis, protects spinal cord, boosts function. IC50s: 7.5-78 nM.Formula:C17H25FN2O4SPurity:98%Color and Shape:SolidMolecular weight:372.45Safironil
CAS:Safironil, a novel antifibrotic, competitively inhibits collagen synthesis and modulates fibrosis, impacting type I/III collagen levels.Formula:C15H23N3O4Purity:99.83%Color and Shape:SolidMolecular weight:309.36Ref: TM-T67961
1mg64.00€5mg136.00€1mL*10mM (DMSO)137.00€10mg192.00€25mg334.00€50mg477.00€100mg662.00€200mg892.00€NAAA-IN-2
CAS:NAAA-IN-2, a selective inhibitor with 50 nM IC50, targets NAAA, an enzyme hydrolyzing PEA/OEA, and may aid inflammation and pain studies.Formula:C11H13N3O2SColor and Shape:SolidMolecular weight:251.3Gü1303
CAS:Gü1303 is a highly potent and reversible inhibitor of Cathepsin K (CatK), with a Ki value of 0.91 nM for mature CatK (mCatK).Formula:C20H22N4O3Color and Shape:SolidMolecular weight:366.41VEL-0230
CAS:VEL-0230 (NC-2300) is a cathespin K inhibitor boosting bone growth and reducing loss, targeting bone diseases and developed by Velcura Therapeutics.Formula:C14H24NNaO5Color and Shape:SolidMolecular weight:309.33SQ 32602
CAS:SQ 32602 is a cathepsin E inhibitor.Formula:C32H52N3O7PColor and Shape:SolidMolecular weight:621.74Tyrosinase-IN-8
Tyrosinase-IN-8, a potent inhibitor of tyrosinase, demonstrates an inhibitory concentration (IC 50) value of 1.6 µM and exhibits low cytotoxicity whileFormula:C16H12O4Color and Shape:SolidMolecular weight:268.26BC-23
CAS:BC-23 (NSC 45382) is a proteasome inhibitor with antitumor and antimicrobial activity for the study of leukemia and small cell lung cancer.Formula:C21H14ClN3O4SPurity:98%Color and Shape:SolidMolecular weight:439.87MMP-1-IN-1
MMP-1-IN-1 is a highly potent MMP-1 inhibitor with an IC 50 of 0.034 μM .Formula:C14H17ClN2O3Color and Shape:SolidMolecular weight:296.75DPP-4-IN-2
CAS:DPP-4-IN-2, analog of Alogliptin with 79 nM IC50, is a research tool for diabetes.Formula:C18H18N6OColor and Shape:SolidMolecular weight:334.38Alvelestat tosylate
CAS:Alvelestat can inhibit neutrophil elastase (NE), which acts an important role in NET formation.Formula:C32H30F3N5O7S2Purity:98%Color and Shape:SolidMolecular weight:717.73BRD-8899
CAS:BRD-8899 is a STK33 inhibitor, with an IC 50 of 11 nM [1].Formula:C17H22N4O3SColor and Shape:SolidMolecular weight:362.45(3S,4S)-A2-32-01
(3S,4S)-A2-32-01, a less active (S,S)-enantiomer of A2-32-01. A2-32-01 is a potent caseinolytic protein proteases (ClpP) inhibitor .Formula:C19H27NO2Color and Shape:SolidMolecular weight:301.42RWJ-58643 HCl
CAS:RWJ 58643 inhibits beta-tryptase & trypsin; at 100µg with budesonide 200µg, reduces symptoms & IL-5; high doses cause late eosinophilia.Formula:C20H27ClN6O4SColor and Shape:SolidMolecular weight:482.984CA 074
CAS:CA 074 is a potent inhibitor of cathepsin B with a Ki value of 2 to 5 nM.CA 074 inhibits ischemic hippocampal neuronal death in primates and attenuatesFormula:C18H29N3O6Purity:98.81%Color and Shape:SolidMolecular weight:383.44Ref: TM-T21509
1mg75.00€1mL*10mM (DMSO)168.00€5mg200.00€10mg313.00€25mg625.00€50mg868.00€100mg1,153.00€XMU-MP-2
CAS:XMU-MP-2 is a potent and selective protease inhibitor with anticancer activity that inhibits the growth of oncogenic BRK-driven tumors in a mouse xenograft
Formula:C32H33F3N8O2Purity:99.29%Color and Shape:SolidMolecular weight:618.65
