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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 981 products of "Proteases/Proteasome"

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  • AGLME

    CAS:
    AGLME is used in a direct enzymatic assay for activated Hageman factor measuring the ability of Hageman factor to hydrolyze the cpd.
    Formula:C11H21N3O4
    Color and Shape:Solid
    Molecular weight:259.3

    Ref: TM-T25007

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Chymase-IN-1

    CAS:
    Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM).
    Formula:C20H15ClNO4PS
    Purity:99.17%
    Color and Shape:Solid
    Molecular weight:431.83

    Ref: TM-T10811

    1mg
    146.00€
    5mg
    349.00€
    1mL*10mM (DMSO)
    384.00€
    10mg
    497.00€
    25mg
    745.00€
    50mg
    999.00€
    100mg
    1,341.00€
    500mg
    2,655.00€
  • TAPI-0

    CAS:
    TAPI-0 is a matrix metalloprotease (MMP) and TACE inhibitor.
    Formula:C24H32N4O5
    Color and Shape:Solid
    Molecular weight:456.53

    Ref: TM-T70664

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • ADAMTS-5-IN-2

    CAS:
    ADAMTS-5-IN-2 is a potent inhibitor of ADAMTS-5, exhibiting an IC50 of 0.71 µM, and holds potential for osteoarthritis research.
    Formula:C17H15N3OS
    Color and Shape:Solid
    Molecular weight:309.39

    Ref: TM-T72868

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • SJA6017

    CAS:
    SJA6017: inhibits calpain-1/2, cathepsins B/L; prevents apoptosis, protects spinal cord, boosts function. IC50s: 7.5-78 nM.
    Formula:C17H25FN2O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:372.45

    Ref: TM-T28786

    1mg
    239.00€
  • Safironil

    CAS:
    Safironil, a novel antifibrotic, competitively inhibits collagen synthesis and modulates fibrosis, impacting type I/III collagen levels.
    Formula:C15H23N3O4
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:309.36

    Ref: TM-T67961

    1mg
    64.00€
    5mg
    136.00€
    1mL*10mM (DMSO)
    137.00€
    10mg
    192.00€
    25mg
    334.00€
    50mg
    477.00€
    100mg
    662.00€
    200mg
    892.00€
  • NAAA-IN-2

    CAS:
    NAAA-IN-2, a selective inhibitor with 50 nM IC50, targets NAAA, an enzyme hydrolyzing PEA/OEA, and may aid inflammation and pain studies.
    Formula:C11H13N3O2S
    Color and Shape:Solid
    Molecular weight:251.3

    Ref: TM-T60378

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Gü1303

    CAS:
    Gü1303 is a highly potent and reversible inhibitor of Cathepsin K (CatK), with a Ki value of 0.91 nM for mature CatK (mCatK).
    Formula:C20H22N4O3
    Color and Shape:Solid
    Molecular weight:366.41

    Ref: TM-T61413

    25mg
    1,927.00€
    50mg
    2,507.00€
    100mg
    3,168.00€
  • VEL-0230

    CAS:
    VEL-0230 (NC-2300) is a cathespin K inhibitor boosting bone growth and reducing loss, targeting bone diseases and developed by Velcura Therapeutics.
    Formula:C14H24NNaO5
    Color and Shape:Solid
    Molecular weight:309.33

    Ref: TM-T69793

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • SQ 32602

    CAS:
    SQ 32602 is a cathepsin E inhibitor.
    Formula:C32H52N3O7P
    Color and Shape:Solid
    Molecular weight:621.74

    Ref: TM-T26218

    25mg
    2,557.00€
    50mg
    3,831.00€
  • Tyrosinase-IN-8


    Tyrosinase-IN-8, a potent inhibitor of tyrosinase, demonstrates an inhibitory concentration (IC 50) value of 1.6 µM and exhibits low cytotoxicity while
    Formula:C16H12O4
    Color and Shape:Solid
    Molecular weight:268.26

    Ref: TM-T72787

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • BC-23

    CAS:
    BC-23 (NSC 45382) is a proteasome inhibitor with antitumor and antimicrobial activity for the study of leukemia and small cell lung cancer.
    Formula:C21H14ClN3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:439.87

    Ref: TM-T26754

    1mg
    99.00€
    5mg
    187.00€
    10mg
    303.00€
    25mg
    547.00€
    50mg
    817.00€
    100mg
    1,225.00€
  • MMP-1-IN-1


    MMP-1-IN-1 is a highly potent MMP-1 inhibitor with an IC 50 of 0.034 μM .
    Formula:C14H17ClN2O3
    Color and Shape:Solid
    Molecular weight:296.75

    Ref: TM-T73175

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • DPP-4-IN-2

    CAS:
    DPP-4-IN-2, analog of Alogliptin with 79 nM IC50, is a research tool for diabetes.
    Formula:C18H18N6O
    Color and Shape:Solid
    Molecular weight:334.38

    Ref: TM-T61018

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Alvelestat tosylate

    CAS:
    Alvelestat can inhibit neutrophil elastase (NE), which acts an important role in NET formation.
    Formula:C32H30F3N5O7S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:717.73

    Ref: TM-T3107L

    25mg
    1,504.00€
    50mg
    1,963.00€
    100mg
    2,520.00€
  • BRD-8899

    CAS:
    BRD-8899 is a STK33 inhibitor, with an IC 50 of 11 nM [1].
    Formula:C17H22N4O3S
    Color and Shape:Solid
    Molecular weight:362.45

    Ref: TM-T61361

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • (3S,4S)-A2-32-01


    (3S,4S)-A2-32-01, a less active (S,S)-enantiomer of A2-32-01. A2-32-01 is a potent caseinolytic protein proteases (ClpP) inhibitor .
    Formula:C19H27NO2
    Color and Shape:Solid
    Molecular weight:301.42

    Ref: TM-T72657

    25mg
    1,288.00€
    50mg
    1,674.00€
    100mg
    2,250.00€
  • RWJ-58643 HCl

    CAS:
    RWJ 58643 inhibits beta-tryptase & trypsin; at 100µg with budesonide 200µg, reduces symptoms & IL-5; high doses cause late eosinophilia.
    Formula:C20H27ClN6O4S
    Color and Shape:Solid
    Molecular weight:482.984

    Ref: TM-T68474

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • CA 074

    CAS:
    CA 074 is a potent inhibitor of cathepsin B with a Ki value of 2 to 5 nM.CA 074 inhibits ischemic hippocampal neuronal death in primates and attenuates
    Formula:C18H29N3O6
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:383.44

    Ref: TM-T21509

    1mg
    75.00€
    1mL*10mM (DMSO)
    168.00€
    5mg
    200.00€
    10mg
    313.00€
    25mg
    625.00€
    50mg
    868.00€
    100mg
    1,153.00€
  • XMU-MP-2

    CAS:

    XMU-MP-2 is a potent and selective protease inhibitor with anticancer activity that inhibits the growth of oncogenic BRK-driven tumors in a mouse xenograft

    Formula:C32H33F3N8O2
    Purity:99.29%
    Color and Shape:Solid
    Molecular weight:618.65

    Ref: TM-T69980

    1mg
    185.00€
    5mg
    459.00€
    10mg
    657.00€
    25mg
    1,026.00€
    50mg
    1,415.00€
    100mg
    1,872.00€
    500mg
    3,734.00€