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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1044 products of "Proteases/Proteasome"

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  • SP-Chymostatin B

    CAS:
    <p>SP-Chymostatin B inhibits proteases like chymotrypsin and papain; less effective on human elastase; works at 100-200 μg/ml.</p>
    Formula:C30H41N7O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:595.69
  • K 579

    CAS:
    <p>K 579 is a dipeptidyl peptidase IV inhibitor.</p>
    Formula:C17H24N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:328.41
  • Antiviral agent 30

    CAS:
    <p>Antiviral Agent 30 (Example 118) is an active compound against HCV and RSV with an inhibitory concentration (IC 50) of greater than 25μM [1].</p>
    Formula:C21H32N2O3S
    Color and Shape:Solid
    Molecular weight:392.56
  • PTIQ

    CAS:
    <p>MMP-3 expression inhibitor</p>
    Formula:C13H17NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:235.28
  • BAY-678 racemate

    CAS:
    <p>BAY-678 racemate: orally active, selective cell-permeable HNE inhibitor with IC50 of 20 nM.</p>
    Formula:C20H15F3N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:400.35
  • WNK-IN-7

    CAS:
    <p>WNK-IN-7 is a potent and selective WNK1 kinase inhibitor.</p>
    Formula:C26H29N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:399.53
  • ABT-770

    CAS:
    <p>ABT-770: an orally potent and selective MMP inhibitor, shown to reduce tumor growth in animal models.</p>
    Formula:C22H22F3N3O6
    Color and Shape:Solid
    Molecular weight:481.42
  • BR351 precursor

    CAS:
    <p>BR351 precursor is a precursor of BR351. BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).</p>
    Formula:C27H32N2O8S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:576.68
  • CA 074

    CAS:
    <p>CA 074 is a potent inhibitor of cathepsin B with a Ki value of 2 to 5 nM.CA 074 inhibits ischemic hippocampal neuronal death in primates and attenuates</p>
    Formula:C18H29N3O6
    Purity:97.80%
    Color and Shape:Solid
    Molecular weight:383.44
  • XMU-MP-2

    CAS:
    <p>XMU-MP-2 is a potent and selective protease inhibitor with anticancer activity that inhibits the growth of oncogenic BRK-driven tumors in a mouse xenograft</p>
    Formula:C32H33F3N8O2
    Purity:99.29%
    Color and Shape:Solid
    Molecular weight:618.65
  • RS-104966

    CAS:
    <p>RS-104966 is an inhibitor of collagenase that acts by inducing the conformational change in the side-chains of the S1 pocket of MMP-1.</p>
    Formula:C19H21NO6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:391.44
  • Ono-3307 mesylate

    CAS:
    <p>no-3307 mesylate is a protease inhibitor that inhibits a variety of proteases and may be used to study pancreatitis.</p>
    Formula:C15H18N4O7S2
    Purity:97.60% - 98.16%
    Color and Shape:Solid
    Molecular weight:430.46
  • Thrombin inhibitor 6

    CAS:
    <p>Thrombin Inhibitor 6, with an IC 50 of 1 nM, acts as a potent anticoagulant by inhibiting thrombin.</p>
    Formula:C18H19ClN4O2S
    Color and Shape:Solid
    Molecular weight:390.89
  • 2',5-Difluoro-2'-deoxycytidine

    CAS:
    <p>2',5-Difluoro-2'-deoxycytidine has potent anti-HCV activity and toxicity to rRNA.</p>
    Formula:C9H11F2N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:263.2
  • Gü1303

    CAS:
    <p>Gü1303 is a highly potent and reversible inhibitor of Cathepsin K (CatK), with a Ki value of 0.91 nM for mature CatK (mCatK).</p>
    Formula:C20H22N4O3
    Color and Shape:Solid
    Molecular weight:366.41
  • LY 135305

    CAS:
    <p>LY 135305 is a inhibition of spontaneous metastasis.</p>
    Formula:C19H20ClN
    Purity:98%
    Color and Shape:Solid
    Molecular weight:297.82
  • Batimastat sodium salt

    CAS:
    <p>Batimastat (BB-94) sodium salt is a broad-spectrum MMP inhibitor (IC50s: 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7, and MMP-3).</p>
    Formula:C23H31N3NaO4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:500.63
  • HCV-IN-37

    CAS:
    <p>HCV-IN-37: potent HCV inhibitor, stable in rat plasma post-oral dose (15 mg/kg), blocks virus entry phase.</p>
    Formula:C31H35F2N5
    Color and Shape:Solid
    Molecular weight:515.64
  • BrBzGCp2

    CAS:
    <p>BrBzGCp2 (p BrBzGSH(Cp)2) is a GLO1 inhibitor with antitumor activities, relieving anxiety, and is useful in researching neurological disorders.</p>
    Formula:C27H38BrN3O6S
    Purity:98.68% - 98.68%
    Color and Shape:Solid
    Molecular weight:612.58
  • ACH-806

    CAS:
    <p>ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.</p>
    Formula:C19H20F3N3O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:411.44