
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(38 products)
- Cysteine Protease(111 products)
- DPP-4(27 products)
- Glutaminase(46 products)
- HIV Protease(507 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(55 products)
- Proteasome(86 products)
- Serine Protease(54 products)
- p97(15 products)
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Found 978 products of "Proteases/Proteasome"
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(Rac)-Tanomastat
CAS:Tanomastat (BAY 12-9566) is an oral biphenyl MMP inhibitor; blocks MMP-2, -3, -9, -13, with anti-invasive and anti-metastatic properties.Formula:C23H19ClO3SColor and Shape:SolidMolecular weight:410.91Glutaminase-IN-4
CAS:Glutaminase-IN-4 (compound 2a) is a glutaminase (GLS) inhibitor (IC50: 2.3 μM).Formula:C23H22N6O2S2Color and Shape:SolidMolecular weight:478.59L 658758
CAS:L 658758 is an inhibitor of serine proteinase.Formula:C16H20N2O9SColor and Shape:SolidMolecular weight:416.4Efegatran sulfate
CAS:Efegatran sulfate (LY294468 sulfate) is a potent thrombin inhibitor used in the treatment of thrombotic disorders.Formula:C21H34N6O7SPurity:≥98% - ≥98%Color and Shape:SolidMolecular weight:514.6(3S,4S)-A2-32-01
(3S,4S)-A2-32-01, a less active (S,S)-enantiomer of A2-32-01. A2-32-01 is a potent caseinolytic protein proteases (ClpP) inhibitor .Formula:C19H27NO2Color and Shape:SolidMolecular weight:301.42MMP-1-IN-1
MMP-1-IN-1 is a highly potent MMP-1 inhibitor with an IC 50 of 0.034 μM .Formula:C14H17ClN2O3Color and Shape:SolidMolecular weight:296.75NAAA-IN-2
CAS:NAAA-IN-2, a selective inhibitor with 50 nM IC50, targets NAAA, an enzyme hydrolyzing PEA/OEA, and may aid inflammation and pain studies.Formula:C11H13N3O2SColor and Shape:SolidMolecular weight:251.3TAPI-0
CAS:TAPI-0 is a matrix metalloprotease (MMP) and TACE inhibitor.Formula:C24H32N4O5Color and Shape:SolidMolecular weight:456.53Tyrosinase-IN-10
CAS:Tyrosinase-IN-10 serves as a partially competitive inhibitor of tyrosinase, demonstrating an inhibition concentration (IC50) value of 1.6 μM against the enzyme'Formula:C16H12O4Color and Shape:SolidMolecular weight:268.26Calpain-2-IN-1
CAS:Calpain-2-IN-1 is a selective calpain-2 inhibitor with Ki values of 181 nM for calpain-1 and 7.8 nM for calpain-2, applicable for neurodegenerative diseases a.Formula:C28H37N3O7Purity:98.05%Color and Shape:SolidMolecular weight:527.61HCV-IN-35
CAS:HCV-IN-35 is a potent inhibitor of HCV and shows potential for infectious disease research.Formula:C30H36ClN5Color and Shape:SolidMolecular weight:502.09Calpain Inhibitor XI
CAS:Calpain Inhibitor XI, a reversible covalent inhibitor of calpain-1, is utilized in the research of neurodegenerative disorders.Formula:C26H40N4O6Color and Shape:SolidMolecular weight:504.62AM 4299 B
CAS:AM 4299 B is a novel inhibitor of a thiol protease.Formula:C16H27N3O7Purity:98%Color and Shape:SolidMolecular weight:373.4MDL 27399
CAS:MDL 27399 suppresses human neutrophil cathepsin G.Formula:C26H36N4O8Color and Shape:SolidMolecular weight:532.59CAA0225
CAS:CAA0225 is a selective inhibitor of cathepsin L. CAA0225 is a probe for autophagic proteolysis.Formula:C28H29N3O5Color and Shape:SolidMolecular weight:487.55MMP13-IN-4
CAS:MMP13-IN-4 (compound 13) is a potent, selective MMP-13 inhibitor with an IC50 of 14.6 μM, implicated in the pathology of osteoarthritis (OA) [1].Formula:C21H17BrN4O5Purity:98%Color and Shape:SolidMolecular weight:485.29Z-LLF-CHO
CAS:Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) effectively inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex with a Ki value of 460 nM.Formula:C29H39N3O5Purity:98%Color and Shape:SolidMolecular weight:509.64Immunoproteasome inhibitor 1
CAS:Potent, reversible immunoproteasome inhibitor; Ki: β5c 1.18 μM, β1i 0.27 μM, β5i 1.91 μM; potential in treating cancer.Formula:C20H26N2O4Color and Shape:SolidMolecular weight:358.43JO146
CAS:JO146为针对沙眼衣原体高温需要蛋白A(CtHtrA)的蛋白酶抑制剂,其对CtHtrA和人中性粒细胞弹性蛋白酶(HNE)的IC50值分别为21.86 μM和1.15 μM,可应用于细菌感染的抑制。Formula:C31H44N3O7PColor and Shape:SolidMolecular weight:601.67GS-9256
CAS:GS-9256 is a selective inhibitor of the HCV NS3 protease, exhibiting favorable pharmacokinetic properties and antiviral activity [1].Formula:C46H56ClF2N6O8PSPurity:98%Color and Shape:SolidMolecular weight:957.46
