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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 978 products of "Proteases/Proteasome"

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  • (Rac)-Tanomastat

    CAS:
    Tanomastat (BAY 12-9566) is an oral biphenyl MMP inhibitor; blocks MMP-2, -3, -9, -13, with anti-invasive and anti-metastatic properties.
    Formula:C23H19ClO3S
    Color and Shape:Solid
    Molecular weight:410.91

    Ref: TM-T62090

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Glutaminase-IN-4

    CAS:
    Glutaminase-IN-4 (compound 2a) is a glutaminase (GLS) inhibitor (IC50: 2.3 μM).
    Formula:C23H22N6O2S2
    Color and Shape:Solid
    Molecular weight:478.59

    Ref: TM-T63137

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • L 658758

    CAS:
    L 658758 is an inhibitor of serine proteinase.
    Formula:C16H20N2O9S
    Color and Shape:Solid
    Molecular weight:416.4

    Ref: TM-T24311

    25mg
    1,504.00€
    50mg
    1,963.00€
    100mg
    2,520.00€
  • Efegatran sulfate

    CAS:
    Efegatran sulfate (LY294468 sulfate) is a potent thrombin inhibitor used in the treatment of thrombotic disorders.
    Formula:C21H34N6O7S
    Purity:≥98% - ≥98%
    Color and Shape:Solid
    Molecular weight:514.6

    Ref: TM-T25364L

    1mg
    290.00€
    5mg
    648.00€
    10mg
    858.00€
    25mg
    1,288.00€
  • (3S,4S)-A2-32-01


    (3S,4S)-A2-32-01, a less active (S,S)-enantiomer of A2-32-01. A2-32-01 is a potent caseinolytic protein proteases (ClpP) inhibitor .
    Formula:C19H27NO2
    Color and Shape:Solid
    Molecular weight:301.42

    Ref: TM-T72657

    25mg
    1,288.00€
    50mg
    1,674.00€
    100mg
    2,250.00€
  • MMP-1-IN-1


    MMP-1-IN-1 is a highly potent MMP-1 inhibitor with an IC 50 of 0.034 μM .
    Formula:C14H17ClN2O3
    Color and Shape:Solid
    Molecular weight:296.75

    Ref: TM-T73175

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • NAAA-IN-2

    CAS:
    NAAA-IN-2, a selective inhibitor with 50 nM IC50, targets NAAA, an enzyme hydrolyzing PEA/OEA, and may aid inflammation and pain studies.
    Formula:C11H13N3O2S
    Color and Shape:Solid
    Molecular weight:251.3

    Ref: TM-T60378

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • TAPI-0

    CAS:
    TAPI-0 is a matrix metalloprotease (MMP) and TACE inhibitor.
    Formula:C24H32N4O5
    Color and Shape:Solid
    Molecular weight:456.53

    Ref: TM-T70664

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Tyrosinase-IN-10

    CAS:
    Tyrosinase-IN-10 serves as a partially competitive inhibitor of tyrosinase, demonstrating an inhibition concentration (IC50) value of 1.6 μM against the enzyme'
    Formula:C16H12O4
    Color and Shape:Solid
    Molecular weight:268.26

    Ref: TM-T72720

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Calpain-2-IN-1

    CAS:
    Calpain-2-IN-1 is a selective calpain-2 inhibitor with Ki values of 181 nM for calpain-1 and 7.8 nM for calpain-2, applicable for neurodegenerative diseases a.
    Formula:C28H37N3O7
    Purity:98.05%
    Color and Shape:Solid
    Molecular weight:527.61

    Ref: TM-T63708

    1mg
    225.00€
  • HCV-IN-35

    CAS:
    HCV-IN-35 is a potent inhibitor of HCV and shows potential for infectious disease research.
    Formula:C30H36ClN5
    Color and Shape:Solid
    Molecular weight:502.09

    Ref: TM-T63406

    25mg
    1,927.00€
    50mg
    2,507.00€
    100mg
    3,168.00€
  • Calpain Inhibitor XI

    CAS:
    Calpain Inhibitor XI, a reversible covalent inhibitor of calpain-1, is utilized in the research of neurodegenerative disorders.
    Formula:C26H40N4O6
    Color and Shape:Solid
    Molecular weight:504.62

    Ref: TM-T72439

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • AM 4299 B

    CAS:
    AM 4299 B is a novel inhibitor of a thiol protease.
    Formula:C16H27N3O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:373.4

    Ref: TM-T25068

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • MDL 27399

    CAS:
    MDL 27399 suppresses human neutrophil cathepsin G.
    Formula:C26H36N4O8
    Color and Shape:Solid
    Molecular weight:532.59

    Ref: TM-T25783

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • CAA0225

    CAS:
    CAA0225 is a selective inhibitor of cathepsin L. CAA0225 is a probe for autophagic proteolysis.
    Formula:C28H29N3O5
    Color and Shape:Solid
    Molecular weight:487.55

    Ref: TM-T26938

    25mg
    1,783.00€
  • MMP13-IN-4

    CAS:
    MMP13-IN-4 (compound 13) is a potent, selective MMP-13 inhibitor with an IC50 of 14.6 μM, implicated in the pathology of osteoarthritis (OA) [1].
    Formula:C21H17BrN4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:485.29

    Ref: TM-T78774

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Z-LLF-CHO

    CAS:
    Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) effectively inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex with a Ki value of 460 nM.
    Formula:C29H39N3O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:509.64

    Ref: TM-T78640

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Immunoproteasome inhibitor 1

    CAS:
    Potent, reversible immunoproteasome inhibitor; Ki: β5c 1.18 μM, β1i 0.27 μM, β5i 1.91 μM; potential in treating cancer.
    Formula:C20H26N2O4
    Color and Shape:Solid
    Molecular weight:358.43

    Ref: TM-T61320

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • JO146

    CAS:
    JO146为针对沙眼衣原体高温需要蛋白A(CtHtrA)的蛋白酶抑制剂,其对CtHtrA和人中性粒细胞弹性蛋白酶(HNE)的IC50值分别为21.86 μM和1.15 μM,可应用于细菌感染的抑制。
    Formula:C31H44N3O7P
    Color and Shape:Solid
    Molecular weight:601.67

    Ref: TM-T73532

    25mg
    1,224.00€
    50mg
    1,594.00€
    100mg
    2,250.00€
  • GS-9256

    CAS:
    GS-9256 is a selective inhibitor of the HCV NS3 protease, exhibiting favorable pharmacokinetic properties and antiviral activity [1].
    Formula:C46H56ClF2N6O8PS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:957.46

    Ref: TM-T71653

    25mg
    14,013.00€
    50mg
    19,926.00€
    100mg
    28,288.00€