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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1044 products of "Proteases/Proteasome"

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  • Elastase-IN-1

    CAS:
    <p>Elastase-IN-1 (Compound Q11) is a non-toxic elastase inhibitor with an IC 50 of 0.897 μM [1].</p>
    Formula:C17H12N4O3
    Color and Shape:Solid
    Molecular weight:320.3
  • HCV-IN-36

    CAS:
    <p>HCV-IN-36: oral HCV inhibitor, EC50 0.016 μM, CC50 8.78 μM, potent antiviral.</p>
    Formula:C30H36ClN5
    Color and Shape:Solid
    Molecular weight:502.09
  • BRD-8899

    CAS:
    <p>BRD-8899 is a STK33 inhibitor, with an IC 50 of 11 nM [1].</p>
    Formula:C17H22N4O3S
    Color and Shape:Solid
    Molecular weight:362.45
  • Tyrosinase-IN-5

    CAS:
    <p>Tyrosinase-IN-5 (16c) inhibits tyrosinase with 0.02 μM IC50, reduces melanogenesis, and is low-toxicity.</p>
    Formula:C18H13N3O6
    Color and Shape:Solid
    Molecular weight:367.31
  • BMS-363131

    CAS:
    <p>BMS-363131 (BMS363131) is a potent and selective trypsin inhibitor with an IC50 value of &lt;1.7 nM.</p>
    Formula:C28H40N6O5
    Purity:97.99%
    Color and Shape:Solid
    Molecular weight:540.65
  • α-Glucosidase-IN-5

    CAS:
    <p>α-Glucosidase-IN-5 (compound 8) is isolated from a twig extract of Polyalthia cinnamomea which is a potent α-glucosidase inhibitor with an IC50 of 57.9 µM.</p>
    Formula:C15H13NO3
    Color and Shape:Solid
    Molecular weight:255.27
  • SAP2-IN-1

    CAS:
    <p>SAP2-IN-1 inhibits secreted aspartate protease 2 (IC50: 0.92 μM), doesn't work in vitro, and helps research infections.</p>
    Formula:C34H29NO7
    Color and Shape:Solid
    Molecular weight:563.6
  • Elasnin

    CAS:
    <p>Elasnin is a reversible inhibitor of elastase for human granulocyte and pancreatic enzymes with IC50 values of 1.3 and 30 µg/ml, respectively.</p>
    Formula:C24H40O4
    Color and Shape:Solid
    Molecular weight:392.57
  • MMP2-IN-2

    CAS:
    <p>MMP2-IN-2 is an MMP-2 inhibitor that inhibits MMP-13, MMP-9, and MMP-8, and can be used in the study of cancer and immune diseases.</p>
    Formula:C13H8N4O4
    Purity:98.09%
    Color and Shape:Solid
    Molecular weight:284.23
  • Glutaminase-IN-4

    CAS:
    <p>Glutaminase-IN-4 (compound 2a) is a glutaminase (GLS) inhibitor (IC50: 2.3 μM).</p>
    Formula:C23H22N6O2S2
    Color and Shape:Solid
    Molecular weight:478.59
  • L 658758

    CAS:
    <p>L 658758 is an inhibitor of serine proteinase.</p>
    Formula:C16H20N2O9S
    Color and Shape:Solid
    Molecular weight:416.4
  • ASPER-29

    CAS:
    <p>ASPER-29, an Asperphenamate analog, inhibits cathepsins L/S with IC50s of 6.03/5.02 μM, useful in cancer migration/invasion research.</p>
    Formula:C31H29BrN2O5S
    Color and Shape:Solid
    Molecular weight:621.54
  • CAY10704

    CAS:
    <p>CAY10704: Potent HCV inhibitor, EC50=17 nM, low cytotoxicity, good in mice, liver-targeted, not hepatotoxic, weak against dengue.</p>
    Formula:C18H20Cl2N2
    Color and Shape:Solid
    Molecular weight:335.27
  • DPP-4-IN-1

    CAS:
    <p>DPP-4-IN-1 inhibits DPP-4 with 49 nM IC50, ideal for diabetes study, akin to Alogliptin.</p>
    Formula:C19H19ClN6
    Color and Shape:Solid
    Molecular weight:366.85
  • AA10 TG2 inhibitor

    CAS:
    <p>AA10 is an irreversible inhibitor of transglutaminase 2 (TG2).</p>
    Formula:C32H36N4O5
    Color and Shape:Solid
    Molecular weight:556.65
  • BAY8040

    CAS:
    <p>BAY8040 is a potent selective human neutrophilic elastase inhibitor with excellent potency and selectivity with promising pharmacokinetic characteristics.</p>
    Formula:C21H16F3N5O2
    Color and Shape:Solid
    Molecular weight:427.38
  • PK44 phosphate

    CAS:
    <p>PK44 phosphate is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV) (IC50: 15.8 nM).</p>
    Formula:C17H19F5N7O5P
    Color and Shape:Solid
    Molecular weight:527.349
  • VEL-0230

    CAS:
    <p>VEL-0230 (NC-2300) is a cathespin K inhibitor boosting bone growth and reducing loss, targeting bone diseases and developed by Velcura Therapeutics.</p>
    Formula:C14H24NNaO5
    Color and Shape:Solid
    Molecular weight:309.33
  • Alicapistat

    CAS:
    <p>Alicapistat (ABT-957) is a human calpains 1 and 2 inhibitor. It can potentially be used to treat Alzheimer's disease (AD).</p>
    Formula:C25H27N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:433.5
  • Tyrosinase-IN-6

    CAS:
    <p>Tyrosinase-IN-6 (4B) is a potent tyrosinase inhibitor (IC50=3.80 μM) with good antioxidant activity.</p>
    Formula:C24H31N3O2
    Color and Shape:Solid
    Molecular weight:393.52