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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 984 products of "Proteases/Proteasome"

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  • Cyclotheonellazole A

    CAS:
    Cyclotheonellazole A inhibits elastase (IC50=0.034nM) & chymotrypsin (IC50=0.62nM), a natural macrocyclic peptide.
    Formula:C44H54N9NaO14S2
    Color and Shape:Solid
    Molecular weight:1020.07

    Ref: TM-T76231

    5mg
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    50mg
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  • AA74-1

    CAS:
    AA74-1 is a potent, selective APEH inhibitor that significantly enhances T-cell proliferation by inhibiting APEH activity [1].
    Formula:C16H28N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:308.42

    Ref: TM-T78134

    5mg
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    50mg
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  • Inogatran

    CAS:
    Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of venous and arterial thrombotic diseases.
    Formula:C21H38N6O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:438.56

    Ref: TM-T11659

    25mg
    1,908.00€
    50mg
    2,502.00€
    100mg
    3,330.00€
  • JW 480

    CAS:
    JW480 is a potent and selective inhibitor of KIAA1363, a serine hydrolase enzyme.
    Formula:C22H23NO2
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:333.42

    Ref: TM-T22883

    2mg
    35.00€
    5mg
    49.00€
    10mg
    79.00€
    25mg
    160.00€
    50mg
    259.00€
    100mg
    416.00€
    200mg
    587.00€
    1mL*10mM (DMSO)
    57.00€
  • NS5A-IN-3

    CAS:
    NS5A-IN-3 is a potent NS5A inhibitor with high efficacy against HCV 1b, good activity on 3a, and strong metabolic stability; superior to daclatasvir.
    Formula:C44H44N6O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:784.86

    Ref: TM-T73223

    25mg
    1,504.00€
    50mg
    1,963.00€
    100mg
    2,520.00€
  • Petesicatib

    CAS:
    Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.
    Formula:C25H23F6N5O4S
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:603.54

    Ref: TM-T16474

    1mg
    100.00€
    5mg
    236.00€
    10mg
    371.00€
    25mg
    735.00€
    50mg
    1,134.00€
    100mg
    1,468.00€
    200mg
    1,972.00€
    1mL*10mM (DMSO)
    314.00€
  • LU-005i

    CAS:
    LU-005i is a powerful inhibitor targeting the β5i subunit of immunoproteasomes, displaying a high potency with an IC 50 value of 6.6 nM, and exhibits selectivity by preferring β5i over the β5c subunit, which has an IC 50 value of 287 nM [1].
    Formula:C31H46N4O7
    Color and Shape:Solid
    Molecular weight:586.72

    Ref: TM-T84755

    10mg
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    50mg
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  • LY52

    CAS:
    LY52 is a matrix metalloproteinase-2 inhibitor. It acts by suppressing tumor invasion and metastasis.
    Formula:C22H24N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:440.45

    Ref: TM-T25765

    25mg
    1,773.00€
    50mg
    2,322.00€
    100mg
    3,060.00€
  • FK706

    CAS:
    FK706, a human neutrophil elastase inhibitor (IC50: 83 nM, Ki: 4.2 nM), also blocks mouse and porcine elastases. Anti-inflammatory.
    Formula:C26H33F3N4NaO7
    Color and Shape:Solid
    Molecular weight:593.556

    Ref: TM-T15285

    25mg
    1,378.00€
    50mg
    1,791.00€
    100mg
    2,872.00€
  • XL-784

    CAS:
    XL-784 is a selective MMP inhibitor with low IC50s for MMP-1,2,3,8,9,13, modulating extracellular matrix remodeling, tumor invasion, and metastasis in cancer.
    Formula:C42H42Cl2F4MgN6O16S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1122.15

    Ref: TM-T13358

    2mg
    359.00€
    1mL*10mM (DMSO)
    33.00€
  • BMS-538305 HCl

    CAS:
    BMS-538305 is a potent, selective inhibitor of dipeptidyl peptidase IV (DPP-IV).
    Formula:C17H27ClN2O2
    Color and Shape:Solid
    Molecular weight:326.86

    Ref: TM-T26850

    25mg
    1,773.00€
    50mg
    2,322.00€
    100mg
    3,060.00€
  • (Rac)-Neurodegenerative Disorder-Targeting Compound 1

    CAS:
    (Rac)-Neurodegenerative Disorder-Targeting Compound 1 is a calpain inhibitor.
    Formula:C28H28N4O4
    Color and Shape:Solid
    Molecular weight:484.55

    Ref: TM-T83527

    5mg
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    50mg
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  • KCC009

    CAS:
    KCC009 is a potent and selective Transglutaminase 2 Inhibitor.
    Formula:C21H22BrN3O5
    Color and Shape:Solid
    Molecular weight:476.32

    Ref: TM-T27717

    25mg
    690.00€
    50mg
    897.00€
    100mg
    1,341.00€
  • JTK-853

    CAS:
    JTK-853: novel non-nucleoside HCV polymerase inhibitor with strong antiviral activity (EC50: 0.38 μM genotype 1a, 0.035 μM 1b).
    Formula:C28H23F7N6O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:704.64

    Ref: TM-T15631

    25mg
    4,374.00€
    50mg
    5,686.00€
    100mg
    7,397.00€
  • MMP-9-IN-8

    CAS:
    MMP-9-IN-8 (Compound 3), an MMP-9 inhibitor, exhibits inhibitory activities of 42.16% at 10 μM and 58.28% at 50 μM.
    Formula:C20H21F4N7O
    Color and Shape:Solid
    Molecular weight:451.42

    Ref: TM-T81777

    5mg
    To inquire
    50mg
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  • Z-DEVD-CMK

    CAS:
    Z-DEVD-CMK irreversibly inhibits various cathepsins in vitro [1].
    Formula:C27H35ClN4O12
    Color and Shape:Solid
    Molecular weight:643.04

    Ref: TM-T80660

    5mg
    To inquire
    50mg
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  • DCLK1-IN-2

    CAS:
    DCLK1-IN-2 (Compound I-5) is a potent inhibitor of DCLK1, exhibiting an IC50 of 171.3 nM, and demonstrates significant antiproliferative effects on SW1990 cell
    Formula:C26H32N8O3S
    Color and Shape:Solid
    Molecular weight:536.65

    Ref: TM-T79421

    5mg
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    50mg
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  • BMS-189664 HCl

    CAS:
    BMS-189664 HCl is a selective and orally active thrombin active site inhibitor.
    Formula:C22H35ClN6O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:515.07

    Ref: TM-T25165L

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • Ravidasvir HCl

    CAS:
    Ravidasvir, also known as PPI-668 and ASC16, is a second-generation, orally active, potent and selective HCV NS5A protein inhibitor.
    Formula:C42H52Cl2N8O6
    Color and Shape:Solid
    Molecular weight:835.828

    Ref: TM-T71964

    1mg
    132.00€
    5mg
    587.00€
    10mg
    888.00€
    25mg
    1,945.00€
  • Z-LVG

    CAS:
    Z-LVG, an irreversible cysteine protease inhibitor and a tripeptide derivative of cystatin C, serves as an inhibitor of viral replication and is utilized in
    Formula:C21H31N3O6
    Color and Shape:Solid
    Molecular weight:421.49

    Ref: TM-T80722

    5mg
    To inquire
    50mg
    To inquire