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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 984 products of "Proteases/Proteasome"

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  • XL-784 free base

    CAS:
    XL-784 free base selectively inhibits MMPs with IC50: MMP-1 (1.9µM), MMP-2 (0.81nM), MMP-3 (120nM), MMP-8 (10.8nM), MMP-9 (18nM), MMP-13 (0.56nM).
    Formula:C21H22ClF2N3O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:549.93

    Ref: TM-T13357

    25mg
    1,908.00€
    50mg
    2,502.00€
    100mg
    3,330.00€
  • MDL-101146, (R)-

    CAS:
    MDL-101146, (R)- is an effective orally active inhibitor of human neutrophil elastase.
    Formula:C29H37F5N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:632.62

    Ref: TM-T25784

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • SSR 69071

    CAS:
    SSR69071: selective neutrophil elastase inhibitor, stronger for humans (Ki=0.0168 nM), may treat COPD, asthma, and reduce heart injury.
    Formula:C27H32N4O7S
    Color and Shape:Solid
    Molecular weight:556.63

    Ref: TM-T21989

    1mg
    105.00€
    5mg
    388.00€
    10mg
    750.00€
  • Ro 32-7315

    CAS:
    Ro 32-7315 is a selective inhibitor of ADAM17.
    Formula:C22H35N3O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:453.6

    Ref: TM-T26105

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • LM-030

    CAS:
    LM-030, also known as BPR277, is a novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2).
    Formula:C46H72N8O12
    Color and Shape:Solid
    Molecular weight:929.11

    Ref: TM-T71417

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Phe-Pro-Ala-pNA

    CAS:
    Phe-Pro-Ala-pNA is a chromogenic substrate utilized for assessing tripeptidyl peptidase activity.
    Formula:C23H27N5O5
    Color and Shape:Solid
    Molecular weight:453.49

    Ref: TM-T84840

    10mg
    To inquire
    50mg
    To inquire
  • ASP-8497

    CAS:
    ASP8497 is a potent DPP-IV inhibitor enhancing GLP-1, used for type 2 diabetes and glucose intolerance.
    Formula:C18H27FN4O7S
    Color and Shape:Solid
    Molecular weight:462.49

    Ref: TM-T30169

    25mg
    1,908.00€
    50mg
    2,502.00€
    100mg
    3,330.00€
  • MDL 27324

    CAS:
    MDL 27324 is an inhibitor of human neutrophil elastase.
    Formula:C29H38F3N5O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:641.7

    Ref: TM-T25782

    25mg
    1,773.00€
    50mg
    2,322.00€
    100mg
    3,060.00€
  • MMP3 inhibitor 1

    CAS:
    MMP3 inhibitor 1 is a potent and highly selective inhibitor of MMP-3 (IC50 of 1 nM).
    Formula:C23H31N3O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:477.57

    Ref: TM-T12082

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • MMP-7-IN-3

    CAS:
    MMP-7-IN-3 (compound 15) is a potent and selective MMP-7 inhibitor, inhibiting renal fibrosis in a unilateral ureteral obstruction mouse model.
    Formula:C34H43ClF3N7O9S
    Purity:99.915%
    Color and Shape:Solid
    Molecular weight:818.26

    Ref: TM-T81778

    1mg
    92.00€
    5mg
    230.00€
    10mg
    371.00€
    25mg
    605.00€
  • BAY-678

    CAS:
    BAY-678: Oral selective human neutrophil elastase inhibitor; IC50: 20 nM; SGC-approved chemical probe.
    Formula:C20H15F3N4O2
    Purity:99.36%
    Color and Shape:Solid
    Molecular weight:400.35

    Ref: TM-T10473

    5mg
    37.00€
    10mg
    60.00€
    25mg
    119.00€
    50mg
    173.00€
    100mg
    264.00€
    200mg
    374.00€
    1mL*10mM (DMSO)
    42.00€
  • Z-FG-NHO-BzOME

    CAS:
    Z-FG-NHO-BzOME is a chemical compound functioning as a cysteine protease inhibitor, selectively targeting and inhibiting cathepsin B, cathepsin L, cathepsin S,
    Formula:C27H27N3O7
    Color and Shape:Solid
    Molecular weight:505.52

    Ref: TM-T80739

    5mg
    To inquire
    50mg
    To inquire
  • KB-R7785

    CAS:
    KB-R7785 is a novel ADAM12/MMP inhibitor improving heart function and insulin sensitivity by blocking HB-EGF and TNF-alpha.
    Formula:C18H27N3O4
    Color and Shape:Solid
    Molecular weight:349.42

    Ref: TM-T70280

    25mg
    4,483.00€
  • Flovagatran sodium

    CAS:
    Flovagatran sodium, a thrombin inhibitor, is used potentially for the treatment of thrombosis.
    Formula:C27H36BN3NaO7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:548.4

    Ref: TM-T27336

    25mg
    1,773.00€
    50mg
    2,322.00€
    100mg
    3,060.00€
  • MDL 101146

    CAS:
    MDL 101146 is an orally active neutrophil elastase inhibitor.
    Formula:C29H37F5N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:632.62

    Ref: TM-T25781

    25mg
    1,773.00€
    50mg
    2,322.00€
    100mg
    3,060.00€
  • O-Benzoylhydroxylamine

    CAS:
    O-Benzoyl hydroxylamine exhibits properties as a dipeptidyl peptidase-IV (DPP-IV) inhibitor and demonstrates antidiabetic effects[1].
    Formula:C7H7NO2
    Color and Shape:Solid
    Molecular weight:137.14

    Ref: TM-T79911

    5mg
    To inquire
    50mg
    To inquire
  • Mergetpa

    CAS:
    Mergetpa, a carboxypeptidase inhibitor, impedes the conversion of kinins and B2 receptor antagonists into metabolites devoid of the C-terminal arginine [1].
    Formula:C7H15N3O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:237.34

    Ref: TM-T78239

    5mg
    To inquire
    50mg
    To inquire
  • Neurodegenerative Disorder-Targeting Compound 1

    CAS:
    Neurodegenerative Disorder-Targeting Compound 1 is an inhibitor of calpain [1].
    Formula:C28H28N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:484.55

    Ref: TM-T13486

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • LU-002i

    CAS:
    LU-002i is a selective inhibitor targeting the human proteasome subunits β2c and β2i, demonstrating an inhibitory concentration (IC50) of 220 nM for β2i [1].
    Formula:C35H52N4O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:640.81

    Ref: TM-T81909

    5mg
    To inquire
    50mg
    To inquire
  • MMP-145

    CAS:
    MMP-145 is used as a protease inhibitor.
    Formula:C20H20N2O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:432.45

    Ref: TM-T25825

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€